Full Text Journal Articles by
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Supra-Binary Polarization in a Ferroelectric Nanowire.

Wentao Xu, Lihua Wang, David ChangMo Yang, Amir Hajibabaei, Yeongjun Lee, Cheolmin Park, Tae-Woo Lee, Kwang S Kim,

The prediction and observation of supra-binary polarization in a ferroelectric nanowire (FNW) covered with a semicylindrical gate that provides an anisotropic electric field in the FNW are reported. There are gate-voltage-driven transitions between four polarization states in the FNW's cross-section, dubbed vertical-up, vertical-down, radial-in, and radial-out. They are determined by ... Read more >>

Adv Mater (Advanced materials (Deerfield Beach, Fla.))
[2021, :e2101981]

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Biomarkers in Nonmetastatic Castrate-Resistant Prostate Cancer: A Step in the Right Direction.

David D Yang, Brandon A Mahal, Luke R G Pike,

JAMA Oncol (JAMA oncology)
[2021, :]

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Amir Toussi, Matthew Ziegelmann, David Yang, Madeleine Manka, Igor Frank, Stephen A Boorjian, Matthew Tollefson, Tobias Köhler, Landon Trost,

J Urol (The Journal of urology)
[2021, :101097JU000000000000179203]

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Elective Pelvic Lymph Node Radiation in Prostate Cancer Revisited.

David D Yang, Paul L Nguyen, Anthony V D'Amico,

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2021, :JCO2100621]

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Efficacy of a Novel Penile Traction Device in Improving Penile Length and Erectile Function Post Prostatectomy: Results from a Single-Center Randomized, Controlled Trial.

Amir Toussi, Matthew Ziegelmann, David Yang, Madeleine Manka, Igor Frank, Stephen A Boorjian, Matthew Tollefson, Tobias Köhler, Landon Trost,

<h4>Purpose</h4>RestoreX is a novel penile traction therapy device, with randomized, controlled data demonstrating improvements in penile length and erectile function after 30 to 90 minutes of daily use in men with Peyronie's disease. We sought to determine if similar improvements could be achieved post prostatectomy.<h4>Materials and methods</h4>Men post prostatectomy were ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001792]

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Targeting the AXL Receptor in Combating Smoking-related Pulmonary Fibrosis.

David C Yang, Shenwen Gu, Ji-Min Li, Ssu-Wei Hsu, Szu-Jung Chen, Wen-Hsin Chang, Ching-Hsien Chen,

Tobacco smoking is a well-known risk factor for both fibrogenesis and fibrotic progression; however, the mechanisms behind these processes remain enigmatic. RTKs (receptor tyrosine kinases) have recently been reported to drive profibrotic phenotypes in fibroblasts during pulmonary fibrosis (PF). Using a phospho-RTK array screen, we identified the RTK AXL as ... Read more >>

Am J Respir Cell Mol Biol (American journal of respiratory cell and molecular biology)
[2021, 64(6):734-746]

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In-The-Wild Interference Characterization and Modelling for Electro-Quasistatic-HBC with Miniaturized Wearables.

David Yang, Parikha Mehrotra, Scott Weigand, Shreyas Sen,

The emergence of Human Body Communication (HBC) as an alternative to wireless body area networks (WBAN) has led to the development of small sized, energy efficient and more secure wearable and implantable devices forming a network in and around the body. Previous studies claim that though HBC is comparatively more ... Read more >>

IEEE Trans Biomed Eng (IEEE transactions on bio-medical engineering)
[2021, PP:]

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EGR1 Addiction in Diffuse Large B-cell Lymphoma.

Shuichi Kimpara, Li Lu, Nguyet M Hoang, Fen Zhu, Paul D Bates, Anusara Daenthanasanmak, Shanxiang Zhang, David T Yang, Amanda Kelm, Yunxia Liu, Yangguang Li, Alexander Rosiejka, Apoorv Kondapelli, Samantha Bebel, Madelyn Chen, Thomas A Waldmann, Christian M Capitini, Lixin Rui,

Early growth response gene (EGR1) is a transcription factor known to be a downstream effector of B-cell receptor signaling and Janus kinase 1 (JAK1) signaling in diffuse large B-cell lymphoma (DLBCL). While EGR1 is characterized as a tumor suppressor in leukemia and multiple myeloma, the role of EGR1 in lymphoma ... Read more >>

Mol Cancer Res (Molecular cancer research : MCR)
[2021, :]

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Depression and Perceived Social Support in Asian American Medical Students.

David Yang, Evrim Oral, Jasmine Kim, Timothy Craft, Michelle B Moore,

<h4>Purpose</h4>Recent data reported that 21.5% of medical students in the United States of America (USA) are Asian American (AA). With the growing focus on developing medical school wellness programs, authors conducted a systematic, nationwide survey to assess prevalence of depression among AA medical students with a focus on disaggregating the ... Read more >>

J Racial Ethn Health Disparities (Journal of racial and ethnic health disparities)
[2021, :]

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Advanced Biophysical Model to Capture Channel Variability for EQS Capacitive HBC.

Arunashish Datta, Mayukh Nath, David Yang, Shreyas Sen,

Human Body Communication (HBC) has come up as a promising alternative to traditional radio frequency (RF) Wireless Body Area Network (WBAN) technologies. This is essentially due to HBC providing a broadband communication channel with enhanced signal security in the physical layer due to lower radiation from the human body as ... Read more >>

IEEE Trans Biomed Eng (IEEE transactions on bio-medical engineering)
[2021, PP:]

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Race- and Age-Related Disparities in Cervical Cancer Mortality.

Stephanie Alimena, Suvidya Lakshmi Pachigolla, Sarah Feldman, David Yang, Peter F Orio, Larissa Lee, Martin King,

<h4>Background</h4>Although the incidence of cervical cancer among younger Black women is now equivalent to that of White women, it is unknown whether the reduced incidence has affected survival rates among younger Black women. The goal of this study was to assess differences in survival by age and race.<h4>Patients and methods</h4>A ... Read more >>

J Natl Compr Canc Netw (Journal of the National Comprehensive Cancer Network : JNCCN)
[2021, :1-7]

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MARCKS cooperates with NKAP to activate NF-kB signaling in smoke-related lung cancer.

Jun Liu, Szu-Jung Chen, Ssu-Wei Hsu, Jun Zhang, Ji-Min Li, David C Yang, Shenwen Gu, Kent E Pinkerton, Ching-Hsien Chen,

<b>Rationale:</b> Cigarette smoking is a major risk factor for lung cancer development and progression; however, the mechanism of how cigarette smoke activates signaling pathways in promoting cancer malignancy remains to be established. Herein, we aimed to determine the contribution of a signaling protein, myristoylated alanine-rich C kinase substrate (MARCKS), in ... Read more >>

Theranostics (Theranostics)
[2021, 11(9):4122-4136]

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Patient Attitudes Towards Surgical Management of Peyronie's Disease Prior to Men's Health Consultation.

Raevti Bole, Masaya Jimbo, Niki Parikh, Cameron Britton, Ajay Gopalakrishna, David Yang, Landon Trost, Sevann Helo, Tobias Kohler, Matthew Ziegelmann,

<h4>Objective</h4>To evaluate clinical characteristics associated with patient attitudes toward surgical treatment of Peyronie's disease (PD) prior to consultation in a high-volume male sexual health clinic.<h4>Methods</h4>From 2014-2018 a prospective database was created of patients presenting to the sexual health clinic at our institution. Multivariable regression analysis was conducted to determine factors ... Read more >>

Urology (Urology)
[2021, :]

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Identifying the Best Candidates for Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography as the Primary Staging Approach Among Men with High-risk Prostate Cancer and Negative Conventional Imaging.

Ting Martin Ma, Andrei Gafita, David Shabsovich, Jesus Juarez, Tristan R Grogan, Pan Thin, Wesley Armstrong, Ida Sonni, Kathleen Nguyen, Vincent Lok, Robert E Reiter, Matthew B Rettig, Michael L Steinberg, Patrick A Kupelian, David D Yang, Vinayak Muralidhar, Carissa Chu, Felix Feng, Ricky Savjani, Jie Deng, Neil R Parikh, Nicholas G Nickols, David Elashoff, Johannes Czernin, Jeremie Calais, Amar U Kishan,

Prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) is an emerging imaging modality with greater sensitivity and specificity over conventional imaging for prostate cancer (PCa) staging. Using data from two prospective trials (NCT03368547 and NCT04050215), we explored predictors of overall upstaging (nodal and metastatic) by PSMA PET/CT among ... Read more >>

Eur Urol Oncol (European urology oncology)
[2021, :]

Cited: 1 time

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Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils.

David S Yang, Arash Saeedi, Aram Davtyan, Mohsen Fathi, Michael B Sherman, Mohammad S Safari, Alena Klindziuk, Michelle C Barton, Navin Varadarajan, Anatoly B Kolomeisky, Peter G Vekilov,

The protein p53 is a crucial tumor suppressor, often called "the guardian of the genome"; however, mutations transform p53 into a powerful cancer promoter. The oncogenic capacity of mutant p53 has been ascribed to enhanced propensity to fibrillize and recruit other cancer fighting proteins in the fibrils, yet the pathways ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2021, 118(10):]

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Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children.

Naïm Ouldali, Julie Toubiana, Denise Antona, Etienne Javouhey, Fouad Madhi, Mathie Lorrot, Pierre-Louis Léger, Caroline Galeotti, Caroline Claude, Arnaud Wiedemann, Noémie Lachaume, Caroline Ovaert, Morgane Dumortier, Jean-Emmanuel Kahn, Alexis Mandelcwajg, Lucas Percheron, Blandine Biot, Jeanne Bordet, Marie-Laure Girardin, David Dawei Yang, Marion Grimaud, Mehdi Oualha, Slimane Allali, Fanny Bajolle, Constance Beyler, Ulrich Meinzer, Michael Levy, Ana-Maria Paulet, Corinne Levy, Robert Cohen, Alexandre Belot, François Angoulvant, ,

<h4>Importance</h4>Multisystem inflammatory syndrome in children (MIS-C) is the most severe pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection, potentially life-threatening, but the optimal therapeutic strategy remains unknown.<h4>Objective</h4>To compare intravenous immunoglobulins (IVIG) plus methylprednisolone vs IVIG alone as initial therapy in MIS-C.<h4>Design, setting, and participants</h4>Retrospective cohort study drawn ... Read more >>

JAMA (JAMA)
[2021, 325(9):855-864]

Cited: 6 times

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Association Between Travel Distance and Use of Postoperative Radiation Therapy Among Men With Organ-Confined Prostate Cancer: Does Geography Influence Treatment Decisions?

Melaku A Arega, David D Yang, Trevor J Royce, Brandon A Mahal, Edward Christopher Dee, Santino S Butler, Sybil Sha, Kent W Mouw, Paul L Nguyen, Vinayak Muralidhar,

<h4>Purpose</h4>After radical prostatectomy, men with adverse pathologic features or a persistent postoperative detectable prostate-specific antigen (PSA) are candidates for postoperative radiation therapy (PORT). Previous data have suggested disparities in receipt of adjuvant radiation therapy for adverse pathologic features according to travel distance. Among patients without adverse pathologic features (pT2 disease ... Read more >>

Pract Radiat Oncol (Practical radiation oncology)
[2021, :]

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Disparities in Refusal of Locoregional Treatment for Prostate Adenocarcinoma.

Edward Christopher Dee, Melaku A Arega, David D Yang, Santino S Butler, Brandon A Mahal, Nina N Sanford, Paul L Nguyen, Vinayak Muralidhar,

<h4>Purpose</h4>We assessed sociodemographic factors associated with and survival implications of refusal of potentially survival-prolonging locoregional treatment (LT, including radiotherapy and surgery) despite provider recommendation among men with localized prostate adenocarcinoma.<h4>Methods</h4>The National Cancer Database (2004-2015) identified men with TxN0M0 prostate cancer who either received or refused LT despite provider recommendation. Multivariable ... Read more >>

JCO Oncol Pract (JCO oncology practice)
[2021, :OP2000839]

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Therapeutic targeting of argininosuccinate synthase 1 (ASS1)-deficient pulmonary fibrosis.

Ji-Min Li, David C Yang, Justin Oldham, Angela Linderholm, Jun Zhang, Jun Liu, Nicholas J Kenyon, Ching-Hsien Chen,

Argininosuccinate synthase 1 (ASS1) serves as a critical enzyme in arginine biosynthesis; however, its role in interstitial lung diseases, particularly idiopathic pulmonary fibrosis (IPF), remains largely unknown. This study aims at characterization and targeting of ASS1 deficiency in pulmonary fibrosis. We find that ASS1 was significantly decreased and inversely correlated ... Read more >>

Mol Ther (Molecular therapy : the journal of the American Society of Gene Therapy)
[2021, 29(4):1487-1500]

Cited: 1 time

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Genome-wide functional screen of 3’UTR variants uncovers causal variants for human disease and evolution

Dustin Griesemer, James Xue, Steven Reilly, Jacob Ulirsch, Kalki Kukreja, Joe Davis, Masahiro Kanai, David Yang, Stephen Montgomery, Carl Novina, Ryan Tewhey, Pardis Sabeti,

3’ untranslated region (3’UTR) variants are strongly associated with human traits and diseases, yet few have been causally identified. We developed the Massively Parallel Reporter Assay for 3’UTRs (MPRAu) to sensitively assay 12,173 3’UTR variants. We applied MPRAu to six human cell lines, focusing on genetic variants associated with genome-wide ... Read more >>

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Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing.

Hyeonu Heo, Yuqi Jin, David Yang, Christopher Wier, Aaron Minard, Narendra B Dahotre, Arup Neogi,

The advent of 3D digital printers has led to the evolution of realistic anatomical organ shaped structures that are being currently used as experimental models for rehearsing and preparing complex surgical procedures by clinicians. However, the actual material properties are still far from being ideal, which necessitates the need to ... Read more >>

Polymers (Basel) (Polymers)
[2020, 13(1):]

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Metabolic reprogramming: A driver of cigarette smoke-induced inflammatory lung diseases.

Linhui Li, David C Yang, Ching-Hsien Chen,

Cigarette smoking is a well-known risk factor for pulmonary diseases, including chronic obstructive pulmonary disease (COPD), asthma and pulmonary fibrosis. Despite major progress in dissecting the mechanisms associated with disease development and progression, findings only represent one aspect of multifaceted disease. A crucial consequence of this approach is that many ... Read more >>

Free Radic Biol Med (Free radical biology & medicine)
[2021, 163:392-401]

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Coronavirus Disease 2019 Pandemic: Impact Caused by School Closure and National Lockdown on Pediatric Visits and Admissions for Viral and Nonviral Infections-a Time Series Analysis.

François Angoulvant, Naïm Ouldali, David Dawei Yang, Mathilde Filser, Vincent Gajdos, Alexis Rybak, Romain Guedj, Valérie Soussan-Banini, Romain Basmaci, Alain Lefevre-Utile, Dominique Brun-Ney, Laure Beaujouan, David Skurnik,

A time series analysis of 871 543 pediatric emergency visits revealed that the coronavirus disease 2019 (COVID-19) lockdown and school closures were associated with a significant decrease in infectious diseases disseminated through airborne or fecal-oral transmission: common cold, gastroenteritis, bronchiolitis, and acute otitis. No change was found for urinary tract ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, 72(2):319-322]

Cited: 8 times

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Rehabilitation therapies in Rett syndrome across the lifespan: A scoping review of human and animal studies.

David Yang, Helen Lee Robertson, Elizabeth G Condliffe, Melissa T Carter, Tammie Dewan, Vithya Gnanakumar,

<h4>Purpose</h4>To perform a scoping review of the evidence for therapeutic interventions to manage functional impairments associated with Rett syndrome (RTT) throughout the lifespan.<h4>Methods</h4>MEDLINE, EMBASE, PsycINFO, CENTRAL, CINAHL, Scopus and Index to Chiropractic Literature were searched systematically up to December 2019. Two investigators independently reviewed all search results and extracted those ... Read more >>

J Pediatr Rehabil Med (Journal of pediatric rehabilitation medicine)
[2021, 14(1):69-96]

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Unexpected lessons from the COVID-19 lockdowns in France: Low impact of school opening on common communicable pediatric airborne diseases.

David Skurnik, Alexis Rybak, David Dawei Yang, Stéphanie Pons, Romain Guedj, Corinne Levy, Robert Cohen, Vincent Gajdos, Loganayagi Vasante, Naïm Ouldali, François Angoulvant,

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

Cited: 1 time

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