Full Text Journal Articles by
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RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections.

Richard Wargodsky, Philip Dela Cruz, John LaFleur, David Yamane, Justin Sungmin Kim, Ivy Benjenk, Eric Heinz, Obinna Ome Irondi, Katherine Farrar, Ian Toma, Tristan Jordan, Jennifer Goldman, Timothy A McCaffrey,

Infection with the SARS-CoV2 virus can vary from asymptomatic, or flu-like with moderate disease, up to critically severe. Severe disease, termed COVID-19, involves acute respiratory deterioration that is frequently fatal. To understand the highly variable presentation, and identify biomarkers for disease severity, blood RNA from COVID-19 patient in an intensive ... Read more >>

PLoS One (PloS one)
[2022, 17(1):e0261679]

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Impact of COVID-19 specific simulation training in improving intubators’ level of comfort during intubations of COVID-19 patients - Results from a USA national survey

Reem Qabas Al Shabeeb, Esther Lee, Muhammad El Shatanofy, Collin F. Mulcahy, Marian L. Sherman, Eric R. Heinz, David P. Yamane,

<h4>Background</h4> Tracheal intubation is a hazardous aerosolizing procedure with a potential risk of spreading SAR-CoV-2 between patients and physicians. <h4>Aim</h4> The purpose of this study was to explore the impact of COVID-19 specific simulation training in improving provider level of comfort during the intubation of COVID-19 patients. <h4>Methods</h4> In this ... Read more >>

(Trends in Anaesthesia & Critical Care)
[2022, :]

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The Growth of Palliative Practice and End of Life Care in an Academic Teaching Intensive Care Unit.

Daniel King, Erica Schockett, Ghazi Rizvi, Daniel Fischer, Richard Amdur, Ivy Benjenk, David Yamane, Benjamin DelPrete, Danielle Davison, Michael Seneff,

<h4>Objective</h4>Dying in the intensive care unit (ICU) has changed over the last twenty years due to increased utilization of palliative care. We sought to examine how palliative medicine (PM) integration into critical care medicine has changed outcomes in end of life including the utilization of do not resuscitate (no cardiopulmonary ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2022, :8850666211069031]

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Effects of a single bolus of hydroxocobalamin on hemodynamics in vasodilatory shock.

Lindsay A Ritter, Mary Maldarelli, Michael T McCurdy, David P Yamane, Danielle Davison, Christopher Parrino, David N Yim, Myounghee Lee, Michael A Mazzeffi, Jonathan H Chow,

<h4>Purpose</h4>Hydroxocobalamin has been observed to cause transient hypertension in healthy subjects, but rigorous studies examining its efficacy are lacking.<h4>Materials and methods</h4>Adults in shock who received hydroxocobalamin from 2017 to 2021 were analyzed retrospectively. Hourly hemodynamics from 24 h before and after treatment were collected, and the difference and hourly change of ... Read more >>

J Crit Care (Journal of critical care)
[2022, 67:66-71]

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Metabolic Syndrome and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19.

Joshua L Denson, Aaron S Gillet, Yuanhao Zu, Margo Brown, Thaidan Pham, Yilin Yoshida, Franck Mauvais-Jarvis, Ivor S Douglas, Mathew Moore, Kevin Tea, Andrew Wetherbie, Rachael Stevens, John Lefante, Jeffrey G Shaffer, Donna Lee Armaignac, Katherine A Belden, Margit Kaufman, Smith F Heavner, Valerie C Danesh, Sreekanth R Cheruku, Catherine A St Hill, Karen Boman, Neha Deo, Vikas Bansal, Vishakha K Kumar, Allan J Walkey, Rahul Kashyap, ,

<h4>Importance</h4>Obesity, diabetes, and hypertension are common comorbidities in patients with severe COVID-19, yet little is known about the risk of acute respiratory distress syndrome (ARDS) or death in patients with COVID-19 and metabolic syndrome.<h4>Objective</h4>To determine whether metabolic syndrome is associated with an increased risk of ARDS and death from COVID-19.<h4>Design, ... Read more >>

JAMA Netw Open (JAMA network open)
[2021, 4(12):e2140568]

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Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry.

Sandeep Tripathi, Imran A Sayed, Heda Dapul, Jeremy S McGarvey, Jennifer A Bandy, Karen Boman, Vishakha K Kumar, Vikas Bansal, Lynn Retford, Sreekanth Cheruku, Margit Kaufman, Smith F Heavner, Valerie C Danesh, Catherine A St Hill, Ashish K Khanna, Utpal Bhalala, Rahul Kashyap, Ognjen Gajic, Allan J Walkey, Katja M Gist,

<h4>Importance</h4>Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population.<h4>Objectives</h4>To describe the epidemiology and outcomes of coronavirus disease 2019 and identify the risk factors associated with critical illness ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(8):e0514]

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EVALUATING APACHE AND SOFA SCORING SYSTEMS IN PATIENTS WITH COVID-19

NIRAJ GOWDA, GIFTY DOMINAH, HAYLEY ROGERS, AMIRA ELSHIKH, SURAJ GOWDA, IVY BENJENK, DAVID YAMANE,

Chest (Chest)
[2021, 160(4):A1077-A1077]

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Frequency and outcomes of gastrointestinal symptoms in patients with Corona Virus Disease-19.

Hayley K Rogers, WonSeok W Choi, Niraj Gowda, Saadia Nawal, Brittney Gordon, Chinelo Onyilofor, Callie M Rogers, David Yamane, Marie L Borum,

<h4>Objectives</h4>To characterize the frequency and association of gastrointestinal (GI) symptoms with outcomes in patients with corona virus disease 2019  (COVID-19) admitted to the hospital.<h4>Methods</h4>Records were retrospectively collected from patients admitted to a tertiary care center in Washington, D.C., with confirmed COVID-19 from March 15, 2020  to July 15, 2020. After adjusting for ... Read more >>

Indian J Gastroenterol (Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology)
[2021, 40(5):502-511]

Cited: 1 time

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Video case review for quality improvement during cardiac arrest resuscitation in the emergency department.

Joseph T Brooks, Ayal Z Pierce, Patrick McCarville, Natalie Sullivan, Anahita Rahimi-Saber, Christopher Payette, Margarita Popova, Narou Koizumi, Ali Pourmand, David Yamane,

<h4>Background</h4>Out-of-hospital cardiac arrests are a leading global cause of mortality. The American Heart Association (AHA) promotes several important strategies associated with improved cardiac arrest (CA) outcomes, including decreasing pulse check time and maintaining a chest compression fraction (CCF) > 0.80. Video review is a potential tool to improve skills and analyse deficiencies ... Read more >>

Int J Clin Pract (International journal of clinical practice)
[2021, 75(10):e14525]

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Association of prehospital antiplatelet therapy with survival in patients hospitalized with COVID-19: A propensity score-matched analysis.

Jonathan H Chow, Ying Yin, David P Yamane, Danielle Davison, Ryan J Keneally, Katrina Hawkins, K Gage Parr, Mustafa Al-Mashat, Jeffery S Berger, Reamer L Bushardt, Michael A Mazzeffi, Stuart J Nelson,

<h4>Purpose</h4>Coronavirus disease 2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk. The impact of prehospital antiplatelet therapy on in-hospital mortality is uncertain.<h4>Methods</h4>This was an observational cohort study of 34 675 patients ≥50 years old from 90 health systems in the United States. Patients were hospitalized with laboratory-confirmed COVID-19 between February 2020 and ... Read more >>

J Thromb Haemost (Journal of thrombosis and haemostasis : JTH)
[2021, 19(11):2814-2824]

Cited: 2 times

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Sedation, narcotic and neuromuscular blockade in mechanically ventilated patients with COVID-19

Ghazi Rizvi, David Yamane, Danielle Davison, Jeffrey Williams, Eric R. Heinz,

<h4>Objective</h4> To describe the sedation, narcotic and neuromuscular blockade usage in ventilated patients with COVID-19 pneumonia. <h4>Design</h4> Single-Center Retrospective Review. <h4>Setting</h4> George Washington University Hospital in Washington, D.C. <h4>Patients</h4> 62 patients with COVID-19 respiratory failure requiring mechanical ventilation admitted from March 2020 to June 2020. <h4>Intervention</h4> None. <h4>Measurements and main ... Read more >>

(Trends in Anaesthesia & Critical Care)
[2021, 39:19-20]

Cited: 0 times

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Hospital-Based Health Care Worker Perceptions of Personal Risk Related to COVID-19.

Everett Chu, Kyung-Min Lee, Ronnie Stotts, Ivy Benjenk, Geoffrey Ho, David Yamane, Billy Mullins, Eric R Heinz,

<h4>Background</h4>Health care workers treating Coronavirus disease 2019 (COVID-19) patients face significant stressors such as caring for critically ill and dying patients, physically demanding care requiring new degrees of personal protective equipment use, risk of contracting the disease, and putting loved ones at risk. This study investigates the stress impact from ... Read more >>

J Am Board Fam Med (Journal of the American Board of Family Medicine : JABFM)
[2021, 34(Suppl):S103-S112]

Cited: 3 times

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Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019.

Jonathan H Chow, Ashish K Khanna, Shravan Kethireddy, David Yamane, Andrea Levine, Amanda M Jackson, Michael T McCurdy, Ali Tabatabai, Gagan Kumar, Paul Park, Ivy Benjenk, Jay Menaker, Nayab Ahmed, Evan Glidewell, Elizabeth Presutto, Shannon Cain, Naeha Haridasa, Wesley Field, Jacob G Fowler, Duy Trinh, Kathleen N Johnson, Aman Kaur, Amanda Lee, Kyle Sebastian, Allison Ulrich, Salvador Peña, Ross Carpenter, Shruti Sudhakar, Pushpinder Uppal, Benjamin T Fedeles, Aaron Sachs, Layth Dahbour, William Teeter, Kenichi Tanaka, Samuel M Galvagno, Daniel L Herr, Thomas M Scalea, Michael A Mazzeffi,

<h4>Background</h4>Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ventilation, intensive care unit (ICU) admission, and in-hospital mortality.<h4>Methods</h4>A retrospective, observational cohort study of adult patients admitted with ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, 132(4):930-941]

Cited: 104 times

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Video Case Review for Quality Improvement During Cardiac Arrest Resuscitation in the Emergency Department

Joseph Brooks, Ayal Pierce, Patrick McCarville, Natalie Sullivan, Anahita Rahimi-Saber, Christopher Payette, Margarita Popova, Narou Koizumi, Ali Pourmand, David Yamane,

<h4>Background: </h4> Cardiac arrests (CA) are a leading global cause of mortality. The American Heart Association (AHA) promotes several important strategies associated with improved cardiac arrest outcomes, including decreasing pulse check time and maintaining a chest compression fraction (CCF) > 0.80. Video review is a potential tool to improve skills ... Read more >>

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YouTube to Teach Central Lines, The Expert vs Learner Perspective.

Daniel King, Danielle Davison, Ivy Benjenk, Eric Heinz, Khashayar Vaziri, Katrina Hawkins, David Yamane,

<h4>Purpose</h4>Instructional videos of medical procedures can be a useful guide for learners, demonstrating proper and safe technique. Open publishing sites such as YouTube are readily accessible, however the content is not peer reviewed and quality of videos vary greatly. Our aim was to evaluate a learner's ability to interpret the ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, :885066621999979]

Cited: 0 times

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Outcomes of Patients With Coronavirus Disease 2019 Receiving Organ Support Therapies: The International Viral Infection and Respiratory Illness Universal Study Registry.

Juan Pablo Domecq, Amos Lal, Christopher R Sheldrick, Vishakha K Kumar, Karen Boman, Scott Bolesta, Vikas Bansal, Michael O Harhay, Michael A Garcia, Margit Kaufman, Valerie Danesh, Sreekanth Cheruku, Valerie M Banner-Goodspeed, Harry L Anderson, Patrick S Milligan, Joshua L Denson, Catherine A St Hill, Kenneth W Dodd, Greg S Martin, Ognjen Gajic, Allan J Walkey, Rahul Kashyap, ,

<h4>Objectives</h4>To describe the outcomes of hospitalized patients in a multicenter, international coronavirus disease 2019 registry.<h4>Design</h4>Cross-sectional observational study including coronavirus disease 2019 patients hospitalized with laboratory-confirmed severe acute respiratory syndrome coronavirus-2 infection between February 15, 2020, and November 30, 2020, according to age and type of organ support therapies.<h4>Setting</h4>About 168 hospitals ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(3):437-448]

Cited: 19 times

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The Impact of Integrating Palliative Medicine Into COVID-19 Critical Care.

Erica Schockett, Mary Ishola, Taylor Wahrenbrock, Annabelle Croskey, Shannon Cain, Ivy Benjenk, Danielle Davison, David Yamane,

<h4>Background</h4>Ensuring high-quality patient-centered care for critically ill coronavirus disease 2019 (COVID-19) patients presents unprecedented challenges. Many patients become critically ill unexpectedly and have not previously discussed their health-care wishes. Clinicians lack experience with this illness and therefore struggle to predict patient outcomes.<h4>Measures</h4>Critical care medicine (CCM) providers were surveyed about the ... Read more >>

J Pain Symptom Manage (Journal of pain and symptom management)
[2021, 62(1):153-158.e1]

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Minimizing Pulse Check Duration Through Educational Video Review.

David Yamane, Patrick McCarville, Natalie Sullivan, Evan Kuhl, Carolyn Robin Lanam, Christopher Payette, Anahita Rahimi-Saber, Jennifer Rabjohns, Andrew D Sparks, Keith Boniface, Aaran Drake,

<h4>Introduction</h4>The American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) recommend pulse checks of less than 10 seconds. We assessed the effect of video review-based educational feedback on pulse check duration with and without point-of-care ultrasound (POCUS).<h4>Methods</h4>Cameras recorded cases of CPR in the emergency department (ED). Investigators reviewed resuscitation videos for ... Read more >>

West J Emerg Med (The western journal of emergency medicine)
[2020, 21(6):276-283]

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Association of Hyperchloremia and Acute Kidney Injury in Patients With Traumatic Brain Injury.

David P Yamane, Sam Maghami, Ada Graham, Khashayar Vaziri, Danielle Davison,

<h4>Introduction</h4>Hypertonic saline is often used to treat patients with traumatic brain injury. It carries the undesired side effect of hyperchloremia, which has been linked to acute kidney injury (AKI). We sought to evaluate the relationship of hyperchloremia and AKI in this population and whether the absolute exposure to hyperchloremia, including ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2022, 37(1):128-133]

Cited: 1 time

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Mortality in patients with hepatic gas on point-of-care ultrasound in cardiac arrest: Does location matter?

Pradip Ramamurti, David Yamane, Sajani Desai, Keith Boniface, Aaran Drake,

<h4>Purpose</h4>Prior research has suggested an association of hepatic venous gas with mortality in cardiac arrest. As point of care ultrasound (POCUS) is frequently used in the context of resuscitation, we sought to evaluate if the presence of hepatic gas on POCUS had a similar mortality association.<h4>Methods</h4>A retrospective review was conducted ... Read more >>

J Clin Ultrasound (Journal of clinical ultrasound : JCU)
[2021, 49(3):205-211]

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Safety and efficacy of vasopressor administration through midline catheters.

Nivedita Prasanna, David Yamane, Naeha Haridasa, Danielle Davison, Andrew Sparks, Katrina Hawkins,

<h4>Context</h4>Vasopressors are commonly administered through Central Venous Catheters (CVCs) as it is considered unsafe to administer them via peripheral IVs, mainly due to the concern of local tissue injury. Unlike peripheral IVs, midline catheters provide a wider lumen with the catheter tip ending in a large peripheral vein. The use ... Read more >>

J Crit Care (Journal of critical care)
[2021, 61:1-4]

Cited: 1 time

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COVID-19 Intubation Safety: A Multidisciplinary, Rapid-Cycle Model of Improvement.

Amy Tronnier, Collin F Mulcahy, Ayal Pierce, Ivy Benjenk, Marian Sherman, Eric R Heinz, Scott Honeychurch, Geoffrey Ho, Kendarius Talton, David Yamane,

The COVID-19 pandemic has forced the health care industry to develop dynamic protocols to maximize provider safety as aerosolizing procedures, specifically intubation, increase the risk of contracting SARS-CoV-2. The authors sought to create a quality improvement framework to ensure safe practices for intubating providers, and describe a multidisciplinary model developed ... Read more >>

Am J Med Qual (American journal of medical quality : the official journal of the American College of Medical Quality)
[2020, 35(6):450-457]

Cited: 1 time

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Pearls and Pitfalls in the Crashing Geriatric Patient.

David P Yamane,

The geriatric population is growing and is the largest utilizer of emergency and critical care services; the emergency clinician should be comfortable in the management of the acutely ill geriatric patient. There are important physiologic changes in geriatric patients, which alters their clinical presentation and management. Age alone should not ... Read more >>

Emerg Med Clin North Am (Emergency medicine clinics of North America)
[2020, 38(4):919-930]

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Double sequential external defibrillation.

Vishak Kumar, David Yamane, Bandar Aljohani, Awad Alsabban, Ali Pourmand,

Resuscitation (Resuscitation)
[2020, 152:212-213]

Cited: 0 times

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A comparison of bivalirudin and heparin for patients on extracorporeal membrane oxygenation.

Matthew A Brown, Farzad Najam, Elizabeth S Pocock, Peter F Munoz, Katherine A Farrar, David P Yamane,

Thromb Res (Thrombosis research)
[2020, 190:76-78]

Cited: 4 times

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