Full Text Journal Articles by
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Thrombolysis in massive and submassive pulmonary embolism during pregnancy and the puerperium: a systematic review.

David Rodriguez, Carlos Jerjes-Sanchez, Sugely Fonseca, Rebeca Garcia-Toto, Jhon Martinez-Alvarado, Jathniel Panneflek, Claudia Ortiz-Ledesma, Francisco Nevarez,

Thrombolysis in high-risk pulmonary embolism (PE) patients is recommended worldwide; however, the evidence for thrombolysis during pregnancy and the immediate puerperium remains unclear. We conducted a systematic review from 1950 to 2019 through PubMed, Ovid/Willey, and Cochrane Library to assess the safety and effectiveness of thrombolysis during pregnancy and the ... Read more >>

J. Thromb. Thrombolysis (Journal of thrombosis and thrombolysis)
[2020, :]

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Recommendations for Clinical Trials in ICH: The Second Hemorrhagic Stroke Academia Industry Roundtable.

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Stroke (Stroke)
[2020, 51(4):1333-1338]

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The Hospital Zambrano Hellion venous thromboembolism rapid response team (PREVENTION-team): Improving pulmonary embolism and deep venous thrombosis patient care.

Raúl Del Toro-Mijares, Carlos Jerjes-Sánchez, David Rodríguez, Jathniel Panneflek, Mauricio Vázquez-Guajardo, Mario A Fabiani, Juan Quintanilla, Luis Manautou, Erasmo de la Peña-Almaguer, Arturo Cadena, Gabriela Cassagne, Guillermo Torre-Amione,

Background:Fast-track worldwide reperfusion programs improve outcomes in ST-elevation myocardial infarction and stroke. Similar programs called Program Evaluation and Review Technique (PERT) focus on submassive and massive pulmonary embolism (PE) excluding deep venous thrombosis (DVT). Methods:PREVENTION-team (Hospital Zambrano Hellion Venous Thromboembolism [VTE] Rapid Response). Primary objective:Fast-track stratification, diagnostics, and treatment (60-90 ... Read more >>

Arch Cardiol Mex (Archivos de cardiologia de Mexico)
[2020, 90(1):28-38]

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Perception of effective access to health services in Territorial Spaces for Training and Reintegration, one year after the peace accords in Colombia: a cross-sectional study

Julián Alfredo Fernández-Niño, Lud Magdy Chaparro, Ana Beatriz Vásquez-Rodríguez, Maylen Liseth Rojas-Botero, Ginna Esmeralda Hernández-Neuta, Ana Maria Peñuela-Poveda, David Alejandro Rodríguez,

Backgrounds : The signing of the peace accords in Colombia created challenges that are inherent to post-conflict transitions. One of those is the process of reintegrating ex-combatants into society, in which ensuring their rights to health is a particularly significant challenge in rural areas affected by armed conflict. These areas, ... Read more >>

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Genetic and morphological variation is associated with differences in cold-water tolerance and geographic expansion among invasive snails (Melanoides tuberculata) in central Texas

Stephen Harding, David Rodriguez, Jacob Jackson, David Huffman,

Abstract Melanoides tuberculata (Thiaridae) is an old-world freshwater snail that is and now circumtropical. After being introduced in the 1960s via the aquarium trade, populations of M. tuberculata are thriving in spring systems of Texas (USA). Field surveys and experimental investigations of temperature tolerance suggest M. tuberculata is stenothermal, and ... Read more >>

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Candida auris: report of an outbreak.

Carme Salvador García, Nuria Tormo Palop, Juan Vicente Mulet Bayona, Mercedes Melero García, David Navalpotro Rodríguez, Manuel Belda Álvarez, María Del Remedio Guna Serrano, Concepción Gimeno Cardona,

Candida auris is an emerging multidrug-resistant yeast that causes serious invasive infections and outbreaks with high mortality. Controlling C. auris is a challenge in which laboratories, clinicians and public health agencies are needed to identify and treat infections and prevent transmission. This review describes the general aspects of the biology, ... Read more >>

Enferm. Infecc. Microbiol. Clin. (Enfermedades infecciosas y microbiologia clinica)
[2020, 38 Suppl 1:39-44]

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Immunosuppression by Mutated Calreticulin Released from Malignant Cells.

Peng Liu, Liwei Zhao, Friedemann Loos, Caroline Marty, Wei Xie, Isabelle Martins, Sylvie Lachkar, Bo Qu, Emmanuelle Waeckel-Énée, Isabelle Plo, William Vainchenker, Franck Perez, David Rodriguez, Carlos López-Otin, Peter van Endert, Laurence Zitvogel, Oliver Kepp, Guido Kroemer,

Mutations affecting exon 9 of the CALR gene lead to the generation of a C-terminally modified calreticulin (CALR) protein that lacks the KDEL endoplasmic reticulum (ER) retention signal and consequently mislocalizes outside of the ER where it activates the thrombopoietin receptor in a cell-autonomous fashion, thus driving myeloproliferative diseases. Here, we ... Read more >>

Mol. Cell (Molecular cell)
[2020, 77(4):748-760.e9]

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Oversedation Zero as a tool for comfort, safety and intensive care unit management.

J Caballero, M García-Sánchez, E Palencia-Herrejón, T Muñoz-Martínez, J M Gómez-García, I Ceniceros-Rozalén, , ,

Sedation is necessary in the management of critically ill patients, both to alleviate suffering and to cure patients with diseases that require admission to the intensive care unit. Such sedation should be appropriate to the patient needs at each timepoint during clinical evolution, and neither too low (undersedation) nor too ... Read more >>

Med Intensiva (Medicina intensiva)
[2020, 44(4):239-247]

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Publisher Correction: An actin-based viscoplastic lock ensures progressive body-axis elongation.

Alicia Lardennois, Gabriella Pásti, Teresa Ferraro, Flora Llense, Pierre Mahou, Julien Pontabry, David Rodriguez, Samantha Kim, Shoichiro Ono, Emmanuel Beaurepaire, Christelle Gally, Michel Labouesse,

An Amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nature (Nature)
[2019, 574(7778):E17]

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Exercise for Nonagenarians: A Systematic Review.

Kyle J Miller, David Suárez-Iglesias, Silvia Varela, David Rodríguez, Carlos Ayán,

BACKGROUND:Physical exercise has been identified as a health promotion strategy for the oldest old. However, scientific evidence regarding the benefits of exercise on nonagenarians is scarce. This systematic review aimed to evaluate the characteristics and methodological quality of investigations that have examined the effects of physical exercise on nonagenarians. METHODS:A ... Read more >>

J Geriatr Phys Ther (Journal of geriatric physical therapy (2001))
[2019, :]

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Low-load pathogen spillover predicts shifts in skin microbiome and survival of a terrestrial-breeding amphibian.

C Guilherme Becker, Molly C Bletz, Sasha E Greenspan, David Rodriguez, Carolina Lambertini, Thomas S Jenkinson, Paulo R Guimarães, Ana Paula A Assis, Robert Geffers, Michael Jarek, Luís Felipe Toledo, Miguel Vences, Célio F B Haddad,

Wildlife disease dynamics are strongly influenced by the structure of host communities and their symbiotic microbiota. Conspicuous amphibian declines associated with the waterborne fungal pathogen Batrachochytrium dendrobatidis (Bd) have been observed in aquatic-breeding frogs globally. However, less attention has been given to cryptic terrestrial-breeding amphibians that have also been declining ... Read more >>

Proc. Biol. Sci. (Proceedings. Biological sciences)
[2019, 286(1908):20191114]

Cited: 2 times

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Pre-emptive deceased-donor kidney transplant: A matched cohort study.

Antonio Franco, Patricio Más-Serrano, Yussel González, Noelia Balibrea, David Rodríguez, María Isabel López, Francisco Javier Pérez Contreras,

INTRODUCTION:Currently, kidney transplantation is the treatment of choice for patients with kidney disease who require replacement therapy. Dialysis is a necessary step, but not mandatory prior to transplantation. There is the possibility of pre-emptive transplantation or transplantation in pre-dialysis, that is, without previous dialysis. The aim of the present study ... Read more >>

Nefrologia (Nefrologia)
[2020, 40(1):32-37]

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Publisher Correction: An actin-based viscoplastic lock ensures progressive body-axis elongation.

Alicia Lardennois, Gabriella Pásti, Teresa Ferraro, Flora Llense, Pierre Mahou, Julien Pontabry, David Rodriguez, Samantha Kim, Shoichiro Ono, Emmanuel Beaurepaire, Christelle Gally, Michel Labouesse,

An Amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nature (Nature)
[2019, 573(7775):E4]

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An actin-based viscoplastic lock ensures progressive body-axis elongation.

Alicia Lardennois, Gabriella Pásti, Teresa Ferraro, Flora Llense, Pierre Mahou, Julien Pontabry, David Rodriguez, Samantha Kim, Shoichiro Ono, Emmanuel Beaurepaire, Christelle Gally, Michel Labouesse,

Body-axis elongation constitutes a key step in animal development, laying out the final form of the entire animal. It relies on the interplay between intrinsic forces generated by molecular motors1-3, extrinsic forces exerted by adjacent cells4-7 and mechanical resistance forces due to tissue elasticity or friction8-10. Understanding how mechanical forces ... Read more >>

Nature (Nature)
[2019, 573(7773):266-270]

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Aspergillus lentulus.

David Rodríguez, Paulette Legarraga,

Rev Chilena Infectol (Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia)
[2019, 36(4):521-522]

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The Central Contributions of Breast Cancer Stem Cells in Developing Resistance to Endocrine Therapy in Estrogen Receptor (ER)-Positive Breast Cancer.

David Rodriguez, Marc Ramkairsingh, Xiaozeng Lin, Anil Kapoor, Pierre Major, Damu Tang,

Breast cancer stem cells (BCSC) play critical roles in the acquisition of resistance to endocrine therapy in estrogen receptor (ER)-positive (ER + ve) breast cancer (BC). The resistance results from complex alterations involving ER, growth factor receptors, NOTCH, Wnt/β-catenin, hedgehog, YAP/TAZ, and the tumor microenvironment. These mechanisms are likely converged ... Read more >>

Cancers (Basel) (Cancers)
[2019, 11(7):]

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Sphenopalatine Ganglion Stimulation to Augment Cerebral Blood Flow.

Natan M Bornstein, Jeffrey L Saver, Hans-Christoph Diener, Philip B Gorelick, Ashfaq Shuaib, Yoram Solberg, Thomas Devlin, Thomas Leung, Carlos A Molina, , ,

Background and Purpose- Many patients with acute ischemic stroke are not eligible for thrombolysis or mechanical reperfusion therapies due to contraindications, inaccessible vascular occlusions, late presentation, or large infarct core. Sphenopalatine ganglion (SPG) stimulation to enhance collateral flow and stabilize the blood-brain barrier offers an alternative, potentially more widely deliverable, ... Read more >>

Stroke (Stroke)
[2019, :STROKEAHA118024582]

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"That's Not His Regular Formula": A Case of Organophosphate Poisoning in an Infant.

Jeannette Dodson, Sing-Yi Feng, David Rodriguez,

INTRODUCTION:Organophosphates (OPs) are the basis of many insecticides and herbicides and are also used as nerve agents. Approximately 1 million unintentional and 2 million suicidal poisonings as well as more than 300,000 fatalities that are reportedly due to OPs are reported each year worldwide. The mortality rate from OP toxicity ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2019, :]

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The prevalence of Leptospira among invasive small mammals on Puerto Rican cattle farms.

Kathryn M Benavidez, Trina Guerra, Madison Torres, David Rodriguez, Joseph A Veech, Dittmar Hahn, Robert J Miller, Fred V Soltero, Alejandro E Pérez Ramírez, Adalberto Perez de León, Iván Castro-Arellano,

Leptospirosis, an emerging infectious disease caused by bacteria of the genus Leptospira, is thought to be the most widespread zoonotic disease in the world. A first step in preventing the spread of Leptospira is delineating the animal reservoirs that maintain and disperse the bacteria. Quantitative PCR (qPCR) methods targeting the ... Read more >>

PLoS Negl Trop Dis (PLoS neglected tropical diseases)
[2019, 13(5):e0007236]

Cited: 1 time

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Trajectory Tracking on Uncertain Complex Networks via NN-Based Inverse Optimal Pinning Control.

Carlos J Vega, Oscar J Suarez, Edgar N Sanchez, Guanrong Chen, Santiago Elvira-Ceja, David I Rodriguez,

A new approach for trajectory tracking on uncertain complex networks is proposed. To achieve this goal, a neural controller is applied to a small fraction of nodes (pinned ones). Such controller is composed of an on-line identifier based on a recurrent high-order neural network, and an inverse optimal controller to ... Read more >>

IEEE Trans Neural Netw Learn Syst (IEEE transactions on neural networks and learning systems)
[2020, 31(3):854-864]

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Downregulation of CYB5D2 is associated with breast cancer progression.

Diane Ojo, David Rodriguez, Fengxiang Wei, Anita Bane, Damu Tang,

We report here that CYB5D2 is associated with tumor suppression function in breast cancer (BC). CYB5D2 expression was significantly reduced in tamoxifen resistant MCF7 cells and in MCF7 cell-derived xenografts treated with TAM. CYB5D2 overexpression induced apoptosis in MCF7 cells; CYB5D2 knockdown enhanced MCF7 cell proliferation. Using the TCGA and ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):6624]

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Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma.

Kim Wong, Carla Daniela Robles-Espinoza, David Rodriguez, Saskia S Rudat, Susana Puig, Miriam Potrony, Chi C Wong, James Hewinson, Paula Aguilera, Joan Anton Puig-Butille, Brigitte Bressac-de Paillerets, Hélène Zattara, Louise van der Weyden, Christopher D M Fletcher, Thomas Brenn, Mark J Arends, Víctor Quesada, Julia A Newton-Bishop, Carlos Lopez-Otin, D Timothy Bishop, Paul W Harms, Timothy M Johnson, Alison B Durham, David B Lombard, David J Adams,

Importance:The protection of telomeres 1 protein (POT1) is a critical component of the shelterin complex, a multiple-protein machine that regulates telomere length and protects telomere ends. Germline variants in POT1 have been linked to familial melanoma, and somatic mutations are associated with a range of cancers including cutaneous T-cell lymphoma ... Read more >>

JAMA Dermatol (JAMA dermatology)
[2019, 155(5):604-609]

Cited: 1 time

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Role of age and comorbidities in mortality of patients with infective endocarditis.

Carlos Armiñanzas, Concepción Fariñas-Alvarez, Jesús Zarauza, Patricia Muñoz, Víctor González Ramallo, Manuel Martínez Sellés, José Mª Miró Meda, Juan Manuel Pericás, Miguel Ángel Goenaga, Guillermo Ojeda Burgos, Regino Rodríguez Álvarez, Laura Castelo Corral, Juan Gálvez-Acebal, Francisco Javier Martínez Marcos, Maria Carmen Fariñas, , Fernando Fernández Sánchez, Mariam Noureddine, Gabriel Rosas, Javier de la Torre Lima, José Aramendi, Elena Bereciartua, María José Blanco, Roberto Blanco, María Victoria Boado, Marta Campaña Lázaro, Alejandro Crespo, Josune Goikoetxea, José Ramón Iruretagoyena, Josu Irurzun Zuazabal, Leire López-Soria, Miguel Montejo, Javier Nieto, David Rodrigo, David Rodríguez, Regino Rodríguez, Yolanda Vitoria, Roberto Voces, Mª Victoria García López, Radka Ivanova Georgieva, Guillermo Ojeda, Isabel Rodríguez Bailón, Josefa Ruiz Morales, Ana María Cuende, Tomás Echeverría, Ana Fuerte, Eduardo Gaminde, Miguel Ángel Goenaga, Pedro Idígoras, José Antonio Iribarren, Alberto Izaguirre Yarza, Xabier Kortajarena Urkola, Carlos Reviejo, Rafael Carrasco, Vicente Climent, Patricio Llamas, Esperanza Merino, Joaquín Plazas, Sergio Reus, Nemesio Álvarez, José María Bravo-Ferrer, Laura Castelo, José Cuenca, Pedro Llinares, Enrique Miguez Rey, María Rodríguez Mayo, Efrén Sánchez, Dolores Sousa Regueiro, Francisco Javier Martínez, Mª Del Mar Alonso, Beatriz Castro, Dácil García Rosado, Mª Del Carmen Durán, Mª Antonia Miguel Gómez, Juan Lacalzada, Ibrahim Nassar, Antonio Plata Ciezar, José Mª Reguera Iglesias, Víctor Asensi Álvarez, Carlos Costas, Jesús de la Hera, Jonnathan Fernández Suárez, Lisardo Iglesias Fraile, Víctor León Arguero, José López Menéndez, Pilar Mencia Bajo, Carlos Morales, Alfonso Moreno Torrico, Carmen Palomo, Begoña Paya Martínez, Ángeles Rodríguez Esteban, Raquel Rodríguez García, Mauricio Telenti Asensio, Manuel Almela, Juan Ambrosioni, Manuel Azqueta, Mercè Brunet, Marta Bodro, Ramón Cartañá, Carlos Falces, Guillermina Fita, David Fuster, Cristina García de la Mària, Marta Hernández-Meneses, Jaume Llopis Pérez, Francesc Marco, José M Miró, Asunción Moreno, David Nicolás, Salvador Ninot, Eduardo Quintana, Carlos Paré, Daniel Pereda, Juan M Pericás, José L Pomar, José Ramírez, Irene Rovira, Elena Sandoval, Marta Sitges, Dolors Soy, Adrián Téllez, José M Tolosana, Bárbara Vidal, Jordi Vila, Iván Adán, Javier Bermejo, Emilio Bouza, Daniel Celemín, Gregorio Cuerpo Caballero, Antonia Delgado Montero, Ana Fernández Cruz, Ana García Mansilla, Mª Eugenia García Leoni, Víctor González Ramallo, Martha Kestler Hernández, Amaia Mari Hualde, Mercedes Marín, Manuel Martínez-Sellés, Mª Cruz Menárguez, Patricia Muñoz, Cristina Rincón, Hugo Rodríguez-Abella, Marta Rodríguez-Créixems, Blanca Pinilla, Ángel Pinto, Maricela Valerio, Pilar Vázquez, Eduardo Verde Moreno, Isabel Antorrena, Belén Loeches, Alejandro Martín Quirós, Mar Moreno, Ulises Ramírez, Verónica Rial Bastón, María Romero, Araceli Saldaña, Jesús Agüero Balbín, Cristina Amado, Carlos Armiñanzas Castillo, Ana Arnaiz García, Manuel Cobo Belaustegui, María Carmen Fariñas, Concepción Fariñas-Álvarez, Rubén Gómez Izquierdo, Iván García, Claudia González-Rico, Manuel Gutiérrez-Cuadra, José Gutiérrez Díez, Marcos Pajarón, José Antonio Parra, Aurelio Sarralde, Ramón Teira, Jesús Zarauza, Fernando Domínguez, Pablo García Pavía, Jesús González, Beatriz Orden, Antonio Ramos, Tomasa Centella, José Manuel Hermida, José Luis Moya, Pilar Martín-Dávila, Enrique Navas, Enrique Oliva, Alejandro Del Río, Soledad Ruiz, Carmen Hidalgo Tenorio, Manuel Almendro Delia, Omar Araji, José Miguel Barquero, Román Calvo Jambrina, Marina de Cueto, Juan Gálvez Acebal, Irene Méndez, Isabel Morales, Luis Eduardo López-Cortés, Arístides de Alarcón, Emilio García, Juan Luis Haro, José Antonio Lepe, Francisco López, Rafael Luque, Luis Javier Alonso, Pedro Azcárate, José Manuel Azcona Gutiérrez, José Ramón Blanco, Lara García-Álvarez, José Antonio Oteo, Mercedes Sanz, Natividad de Benito, Mercé Gurguí, Cristina Pacho, Roser Pericas, Guillem Pons, M Álvarez, A L Fernández, Amparo Martínez, A Prieto, Benito Regueiro, E Tijeira, Marino Vega, Andrés Canut Blasco, José Cordo Mollar, Juan Carlos Gainzarain Arana, Oscar García Uriarte, Alejandro Martín López, Zuriñe Ortiz de Zárate, José Antonio Urturi Matos, Gloria García Domínguez, Antonio Sánchez-Porto, José Mª Arribas Leal, Elisa García Vázquez, Alicia Hernández Torres, Ana Blázquez, Gonzalo de la Morena Valenzuela, Ángel Alonso, Javier Aramburu, Felicitas Elena Calvo, Anai Moreno Rodríguez, Paola Tarabini-Castellani, Eva Heredero Gálvez, Carolina Maicas Bellido, José Largo Pau, Mª Antonia Sepúlveda, Pilar Toledano Sierra, Sadaf Zafar Iqbal-Mirza, Eva Cascales Alcolea, Pilar Egea Serrano, José Joaquín Hernández Roca, Ivan Keituqwa Yañez, Ana Peláez Ballesta, Víctor Soriano, Eduardo Moreno Escobar, Alejandro Peña Monje, Valme Sánchez Cabrera, David Vinuesa García, María Arrizabalaga Asenjo, Carmen Cifuentes Luna, Juana Núñez Morcillo, Mª Cruz Pérez Seco, Aroa Villoslada Gelabert, Carmen Aured Guallar, Nuria Fernández Abad, Pilar García Mangas, Marta Matamala Adell, Mª Pilar Palacián Ruiz, Juan Carlos Porres, Begoña Alcaraz Vidal, Nazaret Cobos Trigueros, María Jesús Del Amor Espín, José Antonio Giner Caro, Roberto Jiménez Sánchez, Amaya Jimeno Almazán, Alejandro Ortín Freire, Monserrat Viqueira González, Pere Pericás Ramis, Mª Ángels Ribas Blanco, Enrique Ruiz de Gopegui Bordes, Laura Vidal Bonet, Mª Carmen Bellón Munera, Elena Escribano Garaizabal, Antonia Tercero Martínez, Juan Carlos Segura Luque,

PURPOSE:The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. METHODS:Prospective cohort study of all patients with IE included in the GAMES Spanish database between ... Read more >>

Eur. J. Intern. Med. (European journal of internal medicine)
[2019, 64:63-71]

Cited: 2 times

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Double-blind, randomized, placebo-controlled trial of allergen-specific immunotherapy with the major allergen Alt a 1.

Ana Isabel Tabar, Luis Prieto, Pilar Alba, Antonio Nieto, Mercedes Rodríguez, Miguel Torrecillas, Beatriz Huertas, Elisa Gómez, Francisco Javier Fernández, Miguel Blanca, David Rodríguez, Ricardo Palacios,

BACKGROUND:There have been few studies conducted on the efficacy and safety of specific immunotherapy with allergen extracts of fungi compared with other allergen extracts, and there are no data on the major allergen Alt a 1 of the fungus Alternaria alternata. OBJECTIVES:We sought to evaluate the efficacy and safety of ... Read more >>

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2019, 144(1):216-223.e3]

Cited: 0 times

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Envarsus, a novelty for transplant nephrologists: Observational retrospective study.

Antonio Franco, Patricio Más-Serrano, Noelia Balibrea, David Rodriguez, Aurora Javaloyes, Marcos Díaz, Isabel Gascón, Amelia Ramon-Lopez, Javier Perez-Contreras, Juan Selva, Ricardo Nalda-Molina,

The aim of this study was to evaluate the trough concentrations (Cptrough) and the tacrolimus dosage regimen after the conversion of Prograf or Advagraf to Envarsus (new pharmaceutical form with MeltDose technology that improves the absorption of fat-soluble drugs) in patients with stable renal transplantation, and their renal function. We ... Read more >>

Nefrologia (Nefrologia)
[2019, 39(5):506-512]

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