Full Text Journal Articles by
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Accessing new microporous polyspirobifluorenes via a C/Si switch.

Andrei Nesmelov, David Lee, Christopher Bejger, Margaret Kocherga, Zachary Lyles, Madeline K Greenier, Ashley Ariel Vitallo, Ghallia Kaouk, Daniel S Jones, Thomas A Schmedake,

Microporous spirosilabifluorene networks were synthesized via Yamamoto coupling of tetrabromospirosilabifluorene precursors. They exhibit bright fluorescence that is quenched in the presence of nitroaromatics. The C/Si switch has subtle effects on the optical properties of the spirobifluorene network and provides a convenient route to 3,3',6,6'-coupled and other polybifluorenes. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(68):9846-9849]

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Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action.

Nayara Braga Emidio, Hayeon Baik, David Lee, René Stürmer, Jörn Heuer, Alysha G Elliott, Mark A T Blaskovich, Katharina Haupenthal, Nicole Tegtmeyer, Werner Hoffmann, Christina I Schroeder, Markus Muttenthaler,

TFF1 is a key peptide for gastrointestinal protection and repair. Its molecular mechanism of action remains poorly understood with synthetic intractability a recognised bottleneck. Here we describe the synthesis of TFF1 and its homodimer and their interactions with mucins and Helicobacter pylori. Synthetic access to TFF1 is an important milestone ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(47):6420-6423]

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The clinical impact of cirrhosis on the postoperative outcomes of patients undergoing bariatric surgery: propensity score-matched analysis of 2011-2017 US hospitals.

David Uihwan Lee, Gregory Hongyuan Fan, David Jeffrey Hastie, Elyse Ann Addonizio, Vibhav Narayan Prakasam, Ryan Richard Ahern, Julie Suh, Kristen Jin Seog, Raffi Karagozian,

<b>Objectives</b>: Since there is increasing number of patients with cirrhosis who require the bariatric procedure due to obesity and obesity-related nonalcoholic steatohepatitis fibrosis, we evaluate the effect of cirrhosis on post-bariatric surgery outcomes.<b>Methods</b>: 2011-2017 National Inpatient Sample was used to isolate bariatric cases, which were stratified by cirrhosis; controls were ... Read more >>

Expert Rev Gastroenterol Hepatol (Expert review of gastroenterology & hepatology)
[2021, :1-10]

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Neutralization of SARS-CoV-2 variants by convalescent and vaccinated serum

Timothy Bates, Hans Leier, Zoe Lyski, Savannah McBride, Felicity Coulter, Jules Weinstein, James Goodman, Zhengchun Lu, Sarah Siegel, Peter Sullivan, Matt Strnad, Amanda Brunton, David Lee, Marcel Curlin, William Messer, Fikadu Tafesse,

We tested human sera from large, demographically balanced cohorts of BNT162b2 vaccine recipients (n=51) and COVID-19 patients (n=44) for neutralizing antibodies against SARS-CoV-2 variants B.1.1.7 and B.1.351. Although the effect is more pronounced in the vaccine cohort, both B.1.1.7 and B.1.351 show significantly reduced levels of neutralization by vaccinated and ... Read more >>

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The effects of AAC video visual scene display technology on the communicative turns of preschoolers with autism spectrum disorder.

Shelley E Chapin, David McNaughton, Janice Light, Ashley McCoy, Jessica Caron, David L Lee,

Over 40% of children with autism spectrum disorder (ASD) experience difficulty in using speech to meet their daily communication needs. Although augmentative and alternative communication (AAC) can be of benefit, the AAC intervention must support beginning communicators in the early social interactions that provide the foundation for more sophisticated communication ... Read more >>

Assist Technol (Assistive technology : the official journal of RESNA)
[2021, :1-11]

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Physical Therapy Considerations and Recommendations for Patients Following Spinal Cord Stimulator Implant Surgery.

Gene Tekmyster, Holly Jonely, David W Lee, Jason Myerson, Melinda Avery, Maxim Moradian, Mehul J Desai,

<h4>Objectives</h4>Spinal cord stimulation (SCS) is an established therapy option in interventional pain medicine. Recent advances in technology have allowed for greater compliance with treatment and improved efficacy in pain control. This article was proposed to fill the gap in the literature addressing this specific patient population and to facilitate further ... Read more >>

Neuromodulation (Neuromodulation : journal of the International Neuromodulation Society)
[2021, :]

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The Impact of Malnutrition on the Hospital and Infectious Outcomes of Patients Admitted With Alcoholic Hepatitis: 2011 to 2017 Analysis of US Hospitals.

David U Lee, Gregory H Fan, David J Hastie, Elyse A Addonizio, Vibhav N Prakasam, Ryan R Ahern, Kristen J Seog, Raffi Karagozian,

<h4>Goals</h4>We specifically evaluate the effect of malnutrition on the infection risks of patients admitted with alcoholic hepatitis using a national registry of hospitalized patients in the United States.<h4>Background</h4>Malnutrition is a common manifestation of alcoholic hepatitis that affects patient outcomes.<h4>Study</h4>2011 to 2017 National Inpatient Sample was used to isolated patients with ... Read more >>

J Clin Gastroenterol (Journal of clinical gastroenterology)
[2021, :]

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A Phase II Study of Autologous Mesenchymal Stromal Cells and c-kit Positive Cardiac Cells, Alone or in Combination, in Patients with Ischemic Heart Failure: The CCTRN CONCERT-HF Trial.

Roberto Bolli, Raul D Mitrani, Joshua M Hare, Carl J Pepine, Emerson C Perin, James T Willerson, Jay H Traverse, Timothy D Henry, Phillip C Yang, Michael P Murphy, Keith L March, Ivonne H Schulman, Sohail Ikram, David P Lee, Connor O'Brien, Joao A Lima, Mohammad R Ostovaneh, Bharath Ambale-Venkatesh, Gregory Lewis, Aisha Khan, Ketty Bacallao, Krystalenia Valasaki, Bangon Longsomboon, Adrian P Gee, Sara Richman, Doris A Taylor, Dejian Lai, Shelly L Sayre, Judy Bettencourt, Rachel W Vojvodic, Michelle L Cohen, Lara Simpson, David Aguilar, Catalin Loghin, Lem Moyé, Ray F Ebert, Barry R Davis, Robert D Simari, ,

<h4>Aims</h4>CONCERT-HF is an NHLBI-sponsored, double-blind, placebo-controlled, Phase II trial designed to determine whether treatment with autologous bone marrow-derived mesenchymal stromal cells (MSCs) and c-kit positive cardiac cells (CPCs), given alone or in combination, is feasible, safe, and beneficial in patients with heart failure (HF) caused by ischemic cardiomyopathy.<h4>Methods and results</h4>Patients ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2021, :]

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Enhanced Weak-Light Detection of Perovskite Photodetectors through Perovskite/Hole-Transport Material Interface Treatment.

David Sunghwan Lee, Jin Hyuck Heo, Jin Kyoung Park, Bong Woo Kim, Hyong Joon Lee, Yun Mi Song, Sang Hyuk Im,

Enhancement in weak-light detection and other photodetection properties was observed for organic-inorganic halide perovskite photodetectors as a result of benzylammonium iodide (BzAI) treatment at the methylammonium lead triiodide (MAPbI<sub>3</sub>) and hole-transport layer (HTL) interface. After treatment, growth of the two-dimensional Ruddlesden-Popper perovskite phase was observed at the MAPbI<sub>3</sub> surface, which ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, :]

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Can eastern wisdom resolve western epidemics? Traditional Chinese medicine therapies and the opioid crisis.

Thomas Efferth, An-Long Xu, Roxana Damiescu, Mita Banerjee, Norbert W Paul, David Y W Lee,

The widespread use of opioids to treat chronic pain led to a nation-wide crisis in the United States. Tens of thousands of deaths annually occur mainly due to respiratory depression, the most dangerous side effect of opioids. Non-opioid drugs and non-pharmacological treatments without addictive potential are urgently required. Traditional Chinese ... Read more >>

J Integr Med (Journal of integrative medicine)
[2021, :]

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Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19

Monique G.P. van der Wijst, Sara Vazquez, George Hartoularos, Paul Bastard, Tianna Grant, Raymund Bueno, David Lee, John Greenland, Yang Sun, Richard Perez, Anton Ogorodnikov, Alyssa Ward, Sabrina Mann, Kara Lynch, Cassandra Yun, Diane Havlir, Gabriel Chamie, Carina Marquez, Bryan Greenhouse, Michail Lionakis, Philip Norris, Larry Dumont, Kathleen Kelly, Peng Zhang, Qian Zhang, Adrian Gervais, Tom Le Voyer, Alexander Whatley, Yichen Si, Ashley Byrne, Alexis Combes, Arjun Arkal Rao, Yun Song, Gabriela Fragiadakis, Kirsten Kangelaris, Carolyn Calfee, David Erle, Carolyn Hendrickson, Matthew Krummel, Prescott Woodruff, Charles Langelier, Jean-Laurent Casanova, Joseph Derisi, Mark Anderson, Chun Jimmie Ye, ,

Type I interferon (IFN-I) neutralizing autoantibodies have been found in some critical COVID-19 patients; however, their prevalence and longitudinal dynamics across the disease severity scale, and functional effects on circulating leukocytes remain unknown. Here, in 284 COVID-19 patients, we found IFN-I autoantibodies in 19% of critical, 6% of severe and ... Read more >>

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Correlative analysis between two commercially available post-prostatectomy genomic tests.

Mohammed Shahait, Mohammed Alshalalfa, Paul L Nguyen, Ayah Al-Fahmawi, Ryan W Dobbs, Priti Lal, David I Lee,

<h4>Background</h4>Multiple genomic tests are available following radical prostatectomy (RP), however, there is a lack of head-to-head evidence for these tests. We sought to compare the performance of two genomic tests in predicting post-RP oncological outcomes.<h4>Methods</h4>A cohort of 16 post-RP patients with adverse pathological features who had obtained both Decipher (D) ... Read more >>

Prostate Cancer Prostatic Dis (Prostate cancer and prostatic diseases)
[2021, :]

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Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy.

Megan E Rosa-Caldwell, Seongkyun Lim, Wesley A Haynie, Jacob L Brown, John William Deaver, Francielly Morena Da Silva, Lisa T Jansen, David E Lee, Michael P Wiggs, Tyrone A Washington, Nicholas P Greene,

<h4>Background</h4>Muscle atrophy is a common pathology associated with disuse, such as prolonged bed rest or spaceflight, and is associated with detrimental health outcomes. There is emerging evidence that disuse atrophy may differentially affect males and females. Cellular mechanisms contributing to the development and progression of disuse remain elusive, particularly protein ... Read more >>

J Cachexia Sarcopenia Muscle (Journal of cachexia, sarcopenia and muscle)
[2021, :]

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Factors Associated With Self-Perceived Hearing Handicap in Adults From Hispanic/Latino Background: Findings From the Hispanic Community Health Study/Study of Latinos.

Michelle L Arnold, Kathryn Hyer, Brent J Small, Theresa Chisolm, Gabrielle H Saunders, Cathy L McEvoy, David J Lee, Sumitrajit Dhar, Kathleen E Bainbridge,

<h4>Objectives</h4>We sought to determine what factors, including acculturation (language and social contact preferences), were associated with self-perceived hearing handicap among adults from Hispanic/Latino background. We utilized the Aday-Andersen behavioral model of health services utilization to frame our hypotheses that predisposing characteristics (age, sex, education, city of residence, Hispanic/Latino background, and ... Read more >>

Ear Hear (Ear and hearing)
[2021, :]

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Current Smoking Raises Risk of Incident Hypertension: Hispanic Community Health Study-Study of Latinos.

Robert C Kaplan, Pedro L Baldoni, Garrett M Strizich, Eliseo J Pérez-Stable, Nancy L Saccone, Carmen A Peralta, Krista M Perreira, Marc D Gellman, Jessica S Williams-Nguyen, Carlos J Rodriguez, David J Lee, Martha Daviglus, Gregory A Talavera, James P Lash, Jianwen Cai, Nora Franceschini,

<h4>Background</h4>Hypertension has been implicated as a smoking-related risk factor for cardiovascular disease but the dose-response relationship is incompletely described. Hispanics, who often have relatively light smoking exposures, have been understudied in this regard.<h4>Methods</h4>We used data from a 6-year follow-up study of US Hispanic adults aged 18-76 to address the dose-response ... Read more >>

Am J Hypertens (American journal of hypertension)
[2021, 34(2):190-197]

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A Comprehensive Update of the Superior Hypogastric Block for the Management of Chronic Pelvic Pain.

Ivan Urits, Ruben Schwartz, Jared Herman, Amnon A Berger, David Lee, Christopher Lee, Alec M Zamarripa, Annabel Slovek, Kelly Habib, Laxmaiah Manchikanti, Alan D Kaye, Omar Viswanath,

<h4>Purpose of review</h4>This is a comprehensive review of the superior hypogastric block for the management of chronic pelvic pain. It reviews the background, including etiology, epidemiology, and current treatment available for chronic pelvic pain. It then presents the superior hypogastric block and reviews the seminal and most recent evidence about ... Read more >>

Curr Pain Headache Rep (Current pain and headache reports)
[2021, 25(3):13]

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Relationship communication and the course of psychological outcomes among couples coping with localised prostate cancer.

Sharon L Manne, Deborah Kashy, Shannon Myers-Virtue, Talia Zaider, David W Kissane, Carolyn J Heckman, Isaac Kim, Frank Penedo, David Lee,

<h4>Objective</h4>How couples communicate about cancer is an important predictor of psychological outcomes for men diagnosed with localised prostate cancer and their spouses. We examined the predictive role of disclosure, responsiveness, mutual avoidance, and holding back on depressive symptoms, psychological adjustment, cancer-specific distress, and cancer concerns.<h4>Methods</h4>Eighty-one prostate cancer patients and their ... Read more >>

Eur J Cancer Care (Engl) (European journal of cancer care)
[2021, :e13401]

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Previously reward-associated sounds interfere with goal-directed auditory processing.

Andy J Kim, David S Lee, Brian A Anderson,

Previously reward-associated stimuli have consistently been shown to involuntarily capture attention in the visual domain. Although previously reward-associated but currently task-irrelevant sounds have also been shown to interfere with visual processing, it remains unclear whether such stimuli can interfere with the processing of task-relevant auditory information. To address this question, ... Read more >>

Q J Exp Psychol (Hove) (Quarterly journal of experimental psychology (2006))
[2021, :1747021821990033]

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Triple-Phase Computed Tomography May Replace Dual-Energy X-ray Absorptiometry Scan for Evaluation of Osteoporosis in Liver Transplant Candidates.

Manhal Izzy, Benyam D Addissie, Juan Pablo Arab, Moira B Hilscher, Amanda Cartee, David C Lee, Yong Lee, Joel G Fletcher, Tony M Keaveny, William Sanchez,

Assessment of bone density is an important part of liver transplantation (LT) evaluation for early identification and treatment of osteoporosis. Dual-energy X-ray absorptiometry (DXA) is currently the standard clinical test for osteoporosis; however, it may contribute to the appointment burden on LT candidates during the cumbersome evaluation process, and there ... Read more >>

Liver Transpl (Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society)
[2021, 27(3):341-348]

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Frequency-specific Electrocochleography and Traveling Wave Time as a Clinical Test for Menière's Disease.

Robert M Conway, Eric M Sugihara, David M Lee, Jaclyn Renker, Pedrom C Sioshansi, Seilesh C Babu,

<h4>Introduction</h4>Menière's disease is a clinical entity with no definitive objective testing. It has been hypothesized that underlying endolymphatic hydrops stiffens the basilar membrane leading to increased speed of the acoustic stimulus, therefore traveling wave velocity has been proposed as an objective test to aid in the diagnosis. The objective of ... Read more >>

Otol Neurotol (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2021, 42(2):290-293]

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Chronic caloric restriction maintains a youthful phosphoproteome in aged skeletal muscle.

Akshay Bareja, James A Draper, Lauren H Katz, David E Lee, Paul A Grimsrud, James P White,

Caloric restriction (CR) can prolong aged skeletal muscle function, yet the molecular mechanisms are not completely understood. We performed phosphoproteomic analysis on muscle from young and old mice fed an ad libitum diet, and old mice fed a CR diet. CR promoted a youthful phosphoproteomic signature, suppressing several known "pro-aging" ... Read more >>

Mech Ageing Dev (Mechanisms of ageing and development)
[2021, 195:111443]

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The effect of malnutrition on the infectious outcomes of hospitalized patients with cirrhosis: analysis of the 2011-2017 hospital data.

David Uihwan Lee, Greg Hongyuan Fan, Ryan Richard Ahern, Raffi Karagozian,

<h4>Background</h4>In patients with cirrhosis, there is a clinical concern that the development of protein-calorie malnutrition will affect the immune system and predispose these patients to increased infectious outcomes.<h4>Aims</h4>In this study, we evaluate the effects of malnutrition on the infectious outcomes of patients admitted with cirrhosis.<h4>Materials and methods</h4>This study used the ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2021, 32(2):269-278]

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Global absence and targeting of protective immune states in severe COVID-19.

Alexis J Combes, Tristan Courau, Nicholas F Kuhn, Kenneth H Hu, Arja Ray, William S Chen, Nayvin W Chew, Simon J Cleary, Divyashree Kushnoor, Gabriella C Reeder, Alan Shen, Jessica Tsui, Kamir J Hiam-Galvez, Priscila Muñoz-Sandoval, Wandi S Zhu, David S Lee, Yang Sun, Ran You, Mélia Magnen, Lauren Rodriguez, K W Im, Nina K Serwas, Aleksandra Leligdowicz, Colin R Zamecnik, Rita P Loudermilk, Michael R Wilson, Chun J Ye, Gabriela K Fragiadakis, Mark R Looney, Vincent Chan, Alyssa Ward, Sidney Carrillo, , Michael Matthay, David J Erle, Prescott G Woodruff, Charles Langelier, Kirsten Kangelaris, Carolyn M Hendrickson, Carolyn Calfee, Arjun Arkal Rao, Matthew F Krummel,

Although infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has pleiotropic and systemic effects in some individuals<sup>1-3</sup>, many others experience milder symptoms. Here, to gain a more comprehensive understanding of the distinction between severe and mild phenotypes in the pathology of coronavirus disease 2019 (COVID-19) and its origins, we ... Read more >>

Nature (Nature)
[2021, 591(7848):124-130]

Cited: 5 times

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Fast and Frugal: Information Processing Related to The Coronavirus Pandemic.

Jody Chin Sing Wong, Janet Zheng Yang, Zhuling Liu, David Lee, Zhiying Yue,

This research focuses on three factors that influence how individuals cognitively process information related to the coronavirus outbreak. Guided by dual-process theories of information processing, we establish how the two different information processing modes (system 1: heuristic processing; system 2: systematic processing) are influenced by individuals' responsibility attribution, discrete negative ... Read more >>

Risk Anal (Risk analysis : an official publication of the Society for Risk Analysis)
[2021, :]

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Greater fuel efficiency is potentially preferable to reducing NOx emissions for aviation's climate impacts.

Agnieszka Skowron, David S Lee, Rubén Rodríguez De León, Ling L Lim, Bethan Owen,

Aviation emissions of nitrogen oxides (NO<sub>x</sub>) alter the composition of the atmosphere, perturbing the greenhouse gases ozone and methane, resulting in positive and negative radiative forcing effects, respectively. In 1981, the International Civil Aviation Organization adopted a first certification standard for the regulation of aircraft engine NO<sub>x</sub> emissions with subsequent ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):564]

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