Full Text Journal Articles by
Author David Backhoff

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Evaluation of age at symptom onset, proband status, and sex as predictors of disease severity in pediatric catecholaminergic polymorphic ventricular tachycardia.

Dania Kallas, Thomas M Roston, Sonia Franciosi, Laura Brett, Krystien V V Lieve, Sit-Yee Kwok, Prince J Kannankeril, Andrew D Krahn, Martin J LaPage, Susan Etheridge, Allison Hill, Christopher Johnsrude, James Perry, Linda Knight, Peter Fischbach, Seshadri Balaji, Svjetlana Tisma-Dupanovic, Ian Law, Joseph Atallah, David Backhoff, Anna Kamp, Peter Kubus, Adam Kean, Peter F Aziz, Joshua Kovach, Yung Lau, Jordana Kron, Sally-Ann Clur, Georgia Sarquella-Brugada, Arthur A M Wilde, Shubhayan Sanatani,

<h4>Background</h4>Children with catecholaminergic polymorphic ventricular tachycardia (CPVT) are at risk for sudden death, and a risk stratification tool does not exist.<h4>Objective</h4>The purpose of this study was to determine whether proband status, age at symptom onset, and/or sex are independent predictors of cardiac events.<h4>Methods</h4>A multicenter, ambispective, cohort of pediatric CPVT patients ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(11):1825-1832]

Cited: 1 time

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Safety of Transseptal Puncture for Access to the Left Atrium in Infants and Children.

Matthias J Müller, David Backhoff, Heike E Schneider, Jana K Dieks, Julia Rieger, Ulrich Krause, Thomas Paul,

Transseptal puncture (TSP) is a standard procedure to obtain access to the left heart. However, data on TSP in infants and children particularly with congenital heart defects (CHD) is sparse. Safety and efficacy of TSP in infants and children < 18 years with normal cardiac anatomy and with CHD were assessed. 327 ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2021, 42(3):685-691]

Cited: 0 times

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Lone Atrial Flutter in Children and Adolescents: Is It Really "Lone"?

Jana-K Dieks, David Backhoff, Heike E Schneider, Matthias J Müller, Ulrich Krause, Thomas Paul,

Atrial flutter (AFL) in children and adolescents beyond the neonatal period in the absence of any underlying myocardial disease ("lone AFL") is rare and data is limited. Our study aims to present clinical and electrophysiological data of presumed "lone AFL" in pediatric patients and discuss the role of endomyocardial biopsy ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2021, 42(2):361-369]

Cited: 0 times

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Epicardial implantation of a leadless pacemaker in a lamb model.

David Backhoff, Teresa Betz, Katja Eildermann, Thomas Paul, Dieter Zenker, Matthew Bonner, Ulrich Krause,

<h4>Background</h4>Pacemaker used in small children typically consist of an abdominally placed generator and epicardially affixed leads, making such a system prone to lead dysfunction during growth. Aim of this study was to investigate the feasibility of epicardial pacing with a leadless pacemaker in a lamb model.<h4>Animals and methods</h4>Seventeen lambs underwent ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2020, 43(12):1481-1485]

Cited: 0 times

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Value of defibrillation threshold testing in children with nontransvenous implantable cardioverter defibrillators: Are routine DFT tests indicated?

David Backhoff, Matthias J Müller, Mohammed Dakna, Andreas Leha, Heike Schneider, Ulrich Krause, Thomas Paul,

<h4>Background</h4>Nontransvenous implanted cardioverter defibrillators (NT-ICD) are used in infants and small children with life-threatening ventricular tachyarrhythmias. With growth, shock vector shift may result in increase of defibrillation threshold (DFT) and fatal ICD failure.<h4>Objectives</h4>To date, the only way to verify ICD function in children with NT-ICD is repetitive DFT testing, which ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2020, 43(8):805-813]

Cited: 0 times

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High density mapping and catheter ablation of atrial tachycardias in adults with congenital heart disease.

Ulrich Krause, Matthias J Müller, Canan Stellmacher, David Backhoff, Heike Schneider, Thomas Paul,

<h4>Aims</h4>We used a new grid-style multi-electrode mapping catheter (Advisor™ HD Grid, Abbott) and investigated its use for high density mapping of atrial tachycardias in adult patients with congenital heart disease.<h4>Patients and methods</h4>All patients with congenital heart disease who had mapping of atrial tachycardias using the new grid-style catheter between March ... Read more >>

Clin Res Cardiol (Clinical research in cardiology : official journal of the German Cardiac Society)
[2020, 109(8):999-1007]

Cited: 0 times

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Double cryoenergy application (freeze-thaw-freeze) at growing myocardium: Lesion volume and effects on coronary arteries late after energy application. Implications for efficacy and safety in pediatric patients.

Heike E Schneider, Maja Stahl, Wolfgang Schillinger, Matthias Müller, David Backhoff, Manfred Schill, Nehle Groene, Ulrich Krause, Matthias Sigler, Thomas Paul,

INTRODUCTION:Cryoenergy is accepted as an alternative to radiofrequency ablation (RFA) in childen for ablation of supraventricular tachycardia substrates. Single cryoenergy application has been shown to be inferior to RFA. Double cryoenergy application has therefore been introduced into clinical practice, but experience concerning efficacy is limited. Coronary artery stenosis has been ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2019, 30(7):1127-1134]

Cited: 1 time

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Transvenous and non-transvenous implantable cardioverter-defibrillators in children, adolescents, and adults with congenital heart disease: who is at risk for appropriate and inappropriate shocks?

Ulrich Krause, Matthias J Müller, Yannic Wilberg, Matthias Pietzka, David Backhoff, Wolfgang Ruschewski, Thomas Paul,

<h4>Aims</h4>Non-transvenous implantable cardioverter-defibrillators (ICDs) as used in small patients and in patients with congenital heart disease (CHD) have not been compared with transvenous systems with respect to safety and efficacy yet. Aim of the present study was to describe the prevalence of and to identify contributing factors for appropriate and ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2019, 21(1):106-113]

Cited: 2 times

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Efficacy and safety of non-transvenous cardioverter defibrillators in infants and young children.

Matthias J Müller, Jana K Dieks, David Backhoff, Heike E Schneider, Wolfgang Ruschewski, Theodor Tirilomis, Thomas Paul, Ulrich Krause,

<h4>Background</h4>Implantable cardioverter defibrillators (ICD) protect from sudden cardiac death (SCD). In infants and young children, ICD implantation and programming is challenging due to small body size, elevated heart rates, and high physical activity.<h4>Purpose</h4>We report our experience applying a non-transvenous ICD (NT-ICD) system to infants and children < 12 years of age and ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2019, 54(2):151-159]

Cited: 2 times

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Long-Term Follow-Up After Radiofrequency Catheter Ablation of Accessory Atrioventricular Pathways in Children.

David Backhoff, Sophia Klehs, Matthias J Müller, Heike E Schneider, Jana-Katharina Dieks, Thomas Paul, Ulrich Krause,

<h4>Objectives</h4>The purpose of this study was to evaluate long-term safety and efficacy of catheter ablation of accessory atrioventricular pathways (AP) in a pediatric cohort.<h4>Background</h4>Radiofrequency catheter ablation of accessory AP is the recommended treatment for patients with atrioventricular re-entrant tachycardia. Data on long-term results ≥1 year after AP ablation in pediatric patients ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(4):448-455]

Cited: 2 times

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Radiofrequency Catheter Ablation of Atrial Tachycardias in Congenital Heart Disease: Results With Special Reference to Complexity of Underlying Anatomy.

Sophia Klehs, Heike E Schneider, David Backhoff, Thomas Paul, Ulrich Krause,

<h4>Background</h4>Radiofrequency catheter ablation has become the treatment strategy of choice for atrial tachyarrhythmias in patients with congenital heart disease (CHD). We analyzed results of radiofrequency catheter ablation in a large cohort of patients with CHD with special reference to complexity of underlying anatomy.<h4>Methods and results</h4>One hundred and forty-four patients with ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2017, 10(12):]

Cited: 7 times

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Effects of Triple Cryoenergy Application on Lesion Formation and Coronary Arteries in the Developing Myocardium.

Ulrich Krause, Filipe D Abreu da Cunha, David Backhoff, Claudius Jacobshagen, Sophia Klehs, Heike E Schneider, Thomas Paul,

To improve long-term outcome after cryoablation of substrates of supraventricular tachycardia, application of two and three consecutive freeze-thaw cycles has been performed. The effect of triple freeze-thaw cycles on lesion formation within developing myocardium and coronary arteries, however, has not been studied yet. In eight piglets (mean age 15 weeks, ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2017, 38(4):663-668]

Cited: 0 times

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Long-Term Follow-Up After Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia in Children.

David Backhoff, Sophia Klehs, Matthias J Müller, Heike E Schneider, Thomas Kriebel, Thomas Paul, Ulrich Krause,

<h4>Background</h4>Catheter ablation of the slow conducting pathway (SP) is treatment of choice for atrioventricular nodal reentrant tachycardia (AVNRT). Although there are abundant data on AVNRT ablation in adult patients, little is known about the long-term results ≥3 years after AVNRT ablation in pediatric patients.<h4>Methods and results</h4>Follow-up data from 241 patients ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2016, 9(11):]

Cited: 10 times

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Internal Cardioverter Defibrillator Indications and Therapies after Atrial Baffle Procedure for d-Transposition of the Great Arteries: A Multicenter Analysis.

David Backhoff, Gunter Kerst, Andrea Peters, Monika Lüdemann, Christian Frische, Michaela Horndasch, Gabriele Hessling, Thomas Paul, Ulrich Krause,

<h4>Background</h4>Sudden cardiac death (SCD) is the most important cause of late mortality after atrial baffle procedure for d-transposition of the great arteries (d-TGA). Experience with internal cardioverter defibrillator (ICD) therapy in this population is limited. We conducted a multicenter cohort study to determine the current state of ICD therapy in ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2016, 39(10):1070-1076]

Cited: 5 times

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Radiofrequency Catheter Ablation of Accessory Atrioventricular Pathways in Infants and Toddlers ≤ 15 kg.

David Backhoff, Sophia Klehs, Matthias J Müller, Heike Schneider, Thomas Kriebel, Thomas Paul, Ulrich Krause,

Accessory atrioventricular pathways (AP) are the most common substrate for paroxysmal supraventricular tachycardia in infants and small children. Up-to-date data on AP ablation in infants and small children are limited. The aim of the present study was to gain additional insight into radiofrequency (RF) catheter ablation of AP in infants ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2016, 37(5):892-898]

Cited: 6 times

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Contact force monitoring during catheter ablation of intraatrial reentrant tachycardia in patients with congenital heart disease.

Ulrich Krause, David Backhoff, Sophia Klehs, Heike E Schneider, Thomas Paul,

<h4>Background</h4>Monitoring of catheter contact force during catheter ablation of atrial fibrillation has been shown to increase efficacy and safety. However, almost no data exists on the use of this technology in catheter ablation of intraatrial reentrant tachycardia in patients with congenital heart disease. The aim of the present study was ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2016, 46(2):191-198]

Cited: 2 times

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Transbaffle catheter ablation of atrial re-entrant tachycardia within the pulmonary venous atrium in adult patients with congenital heart disease.

Ulrich Krause, David Backhoff, Sophia Klehs, Heike E Schneider, Thomas Paul,

Catheter ablation of atrial re-entrant tachycardia in patients after atrial switch procedure for transposition of the great arteries or with a Fontan circulation is technically challenging if the critical part of the re-entry circuit is located within the pulmonary venous atrium (PVA). We report our experience in transbaffle access (TBA) ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2016, 18(7):1055-1060]

Cited: 5 times

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Catheter ablation of pediatric AV nodal reentrant tachycardia: results in small children.

Ulrich Krause, David Backhoff, Sophia Klehs, Thomas Kriebel, Thomas Paul, Heike E Schneider,

<h4>Background</h4>AV nodal reentrant tachycardia (AVNRT) is commonly encountered in pediatric patients. Definite treatment can be achieved by catheter ablation. The purpose of the study was to evaluate the efficacy and safety of AVNRT ablation focusing on children with a body weight ≤25 kg.<h4>Patients and results</h4>Catheter ablation of AVNRT was attempted in ... Read more >>

Clin Res Cardiol (Clinical research in cardiology : official journal of the German Cardiac Society)
[2015, 104(11):990-997]

Cited: 7 times

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Catheter-based ablation of supraventricular tachycardias in a paediatric population – a decade of experience at a single centre

Backhoff David, Bahrke Sophia, Kriebel Thomas, Müller Matthias, Schneider Heike, Paul Thomas, Krause Ulrich,

Mol Cell Pediatr (Molecular and cellular pediatrics)
[2014, 1(Suppl 1):]

Cited: 0 times

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Formation of multiple conduit aneurysms following Matrix P conduit implantation in a boy with tetralogy of Fallot and pulmonary atresia.

David Backhoff, Michael Steinmetz, Matthias Sigler, Heike Schneider,

We report on a 6-year old boy with tetralogy of Fallot and pulmonary atresia in whom a 16 m Matrix P conduit was implanted between the pulmonary artery and the right ventricle at the age of 16 months. Five years later he developed severe stenosis of the distal conduit anastomosis. ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2014, 46(3):500-502]

Cited: 2 times

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ICD therapy for primary prevention of sudden cardiac death after Mustard repair for d-transposition of the great arteries.

David Backhoff, Matthias Müller, Wolfgang Ruschewski, Thomas Paul, Ulrich Krause,

<h4>Background</h4>Years and decades after the Mustard atrial switch repair for d-Transposition of the great arteries, there is a subset of patients at increased risk for sudden cardiac death due to ventricular tachyarrhythmias. To date, little is known about indications, efficacy and benefit of internal cardioverter defibrillator (ICD) therapy indication in ... Read more >>

Clin Res Cardiol (Clinical research in cardiology : official journal of the German Cardiac Society)
[2014, 103(11):894-901]

Cited: 12 times

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Severe constrictive pericarditis after parvovirus B19 and human herpes virus 6 infection in a 9-year-old girl.

David Backhoff, Michael Steinmetz, Wolfgang Ruschewski, Barbara Stastny, Reinhard Kandolf, Ulrich Krause,

We report on a 9-year-old girl who developed signs of congestive heart failure with significant ascites due to constrictive pericarditis. Cardiac catheterization was performed to establish the diagnosis and to rule out restrictive cardiomyopathy. Endomyocardial biopsies were positive for activated macrophages and small-vessel disease, but no viral genomes were detected. ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2013, 34(8):2089-2092]

Cited: 2 times

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