Full Text Journal Articles by
Author Darlene Taylor

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Highlighting strengths and resources that increase ownership of cervical cancer screening for Indigenous communities in Northern British Columbia: Community-driven approaches.

Alexanne Dick, Travis Holyk, Darlene Taylor, Charlotte Wenninger, Judith Sandford, Laurie Smith, Gina Ogilvie, Alexandra Thomlinson, Sheona Mitchell-Foster,

<h4>Objective</h4>To examine the unique and diverse strengths held by rural and remote Indigenous communities in northern British Columbia, including multi-generational support systems in health and wellness, profound connections to the land, and strong cultural foundations, and harness these strengths, allowing communities to engage in innovative and empowering health and wellness ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, :]

Cited: 0 times

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Using rheology to quantify the effects of localized collagenase treatments on uterine fibroid digestion.

Ria D Corder, Sashi V Gadi, Robert B Vachieri, Friederike L Jayes, John M Cullen, Saad A Khan, Darlene K Taylor,

Uterine fibroids are stiff, benign tumors containing excessive, disordered collagens that occur in 70-80% of women before age 50 and cause bleeding and pain. Collagenase Clostridium histolyticum (CCH) is a bacterial enzyme capable of digesting the collagens present in fibroids. By combining CCH with injectable drug delivery systems to enhance ... Read more >>

Acta Biomater (Acta biomaterialia)
[2021, :]

Cited: 0 times

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Post-test comparison of HIV test knowledge and changes in sexual risk behaviour between clients accessing HIV testing online versus in-clinic.

Travis Salway, Kimberly Thomson, Darlene Taylor, Devon Haag, Elizabeth Elliot, Tom Wong, Christopher K Fairley, Troy Grennan, Jean Shoveller, Gina Ogilvie, Mark Gilbert,

<h4>Objective</h4>Internet-based HIV testing offers the potential to address privacy-related barriers to testing and increase frequency of testing but may result in missed opportunities related to sexual health education and prevention that typically occur in face-to-face encounters. In this study, we assessed the HIV test knowledge and sexual risk behaviour of ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2019, 95(2):102-107]

Cited: 2 times

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Effectiveness of text messaging interventions on prevention, detection, treatment, and knowledge outcomes for sexually transmitted infections (STIs)/HIV: a systematic review and meta-analysis.

Darlene Taylor, Carole Lunny, Petra Lolić, Orion Warje, Jasmina Geldman, Tom Wong, Mark Gilbert, Richard Lester, Gina Ogilvie,

<h4>Background</h4>Rates of STIs continue to rise worldwide, and novel evidence-based interventions such as text messaging aimed at improving client services are needed. We conducted a meta-analysis to evaluate text messaging to support STI/HIV prevention and treatment interventions.<h4>Methods</h4>We included articles that reported findings from randomized controlled trials (RTCs) involving adults and ... Read more >>

Syst Rev (Systematic reviews)
[2019, 8(1):12]

Cited: 10 times

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In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix.

Jodie M Fleming, Susan T Yeyeodu, Ashley McLaughlin, Darren Schuman, Darlene K Taylor,

The extracellular matrix (ECM) contributes to tumor progression through changes induced by tumor and stromal cell signals that promote increased ECM density and stiffness. The increase in ECM stiffness is known to promote tumor cell invasion into surrounding tissues and metastasis. In addition, this scar-like ECM creates a protective barrier ... Read more >>

ACS Chem Biol (ACS chemical biology)
[2018, 13(10):2825-2840]

Cited: 4 times

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Sustained Reduction in Sexual Behavior that May Pose a Risk of HIV Transmission Following Diagnosis During Early HIV Infection Among Gay Men in Vancouver, British Columbia.

Mark Gilbert, Darlene Taylor, Warren Michelow, Daniel Grace, Robert Balshaw, Michael Kwag, Elgin Lim, Benedikt Fischer, David Patrick, Gina Ogilvie, Daniel Coombs, Malcolm Steinberg, Michael Rekart,

Increased viral load during early HIV infection (EHI) disproportionately contributes to HIV transmission among gay men. We examined changes in sexual behavior that may pose a risk of HIV transmission (condomless anal sex (AS) with a serodiscordant or unknown status partner, CAS-SDU) in a cohort of 25 gay men newly ... Read more >>

AIDS Behav (AIDS and behavior)
[2018, 22(7):2068-2078]

Cited: 3 times

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Improving linkage to HIV care at low-threshold STI/HIV testing sites: An evaluation of the Immediate Staging Pilot Project in Vancouver, British Columbia.

Bobbi Brownrigg, Darlene Taylor, Felicia Phan, Irvine Sandstra, Rochelle Stimpson, Rolando Barrios, Richard Lester, Gina Ogilvie,

<h4>Objectives</h4>The objective of the Immediate Staging Pilot Project (ISPP) was to improve linkage to human immunodeficiency virus (HIV) care by increasing the number of referrals made to HIV care, and to decrease the time between diagnosis and linkage to care for newly diagnosed HIV clients. This pilot had the potential ... Read more >>

Can J Public Health (Canadian journal of public health = Revue canadienne de sante publique)
[2017, 108(1):e79-e84]

Cited: 2 times

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On the duration of the period between exposure to HIV and detectable infection.

Bernhard P Konrad, Darlene Taylor, Jessica M Conway, Gina S Ogilvie, Daniel Coombs,

HIV infection cannot be detected immediately after exposure because plasma viral loads are too small initially. The duration of this phase of infection (the "eclipse period") is difficult to estimate because precise dates of exposure are rarely known. Therefore, the reliability of clinical HIV testing during the first few weeks ... Read more >>

Epidemics (Epidemics)
[2017, 20:73-83]

Cited: 9 times

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Knowledge and Perceptions of Latent Tuberculosis Infection among Chinese Immigrants in a Canadian Urban Centre.

Jie Gao, Nicole S Berry, Darlene Taylor, Scott A Venners, Victoria J Cook, Maureen Mayhew,

Background. Since most tuberculosis (TB) cases in immigrants to British Columbia (BC), Canada, develop from latent TB infection (LTBI), treating immigrants for LTBI can contribute to the eradication of TB. However, adherence to LTBI treatment is a challenge that is influenced by knowledge and perceptions. This research explores Chinese immigrants' ... Read more >>

Int J Family Med (International journal of family medicine)
[2015, 2015:546042]

Cited: 5 times

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Correlates of women's intentions to be screened for human papillomavirus for cervical cancer screening with an extended interval.

Gina S Ogilvie, Laurie W Smith, Dirk van Niekerk, Fareeza Khurshed, Heather N Pedersen, Darlene Taylor, Katharine Thomson, Sandra B Greene, Suzanne M Babich, Eduardo L Franco, Andrew J Coldman,

<h4>Background</h4>High-risk HPV DNA testing has been proposed as a primary tool for cervical cancer screening (HPV-CCS) as an alternative to the Papanicolaou cytology- method. This study describes factors associated with women's intentions to attend cervical cancer screening if high-risk HPV DNA testing (HPV-CCS) was implemented as a primary screening tool, ... Read more >>

BMC Public Health (BMC public health)
[2016, 16:213]

Cited: 9 times

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Assessment of Capacity to Consent by Nurses Who Deliver Health Care to Patients Who Misuse Substances.

Darlene Taylor, Anita Ho, Louise C Mâsse, Natasha Van Borek, Neville Li, Michelle Patterson, Gina Ogilvie, Jane A Buxton,

This qualitative study explored the current practice that nurses use to assess capacity to consent to health care (CTC-HC) in street outreach settings. Key informant interviews were conducted with a purposive sample of nurses from each of British Columbia's five regional health authorities, allowing nurses to describe their lived experiences ... Read more >>

Glob Qual Nurs Res (Global qualitative nursing research)
[2016, 3:2333393616671076]

Cited: 0 times

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Reorienting risk to resilience: street-involved youth perspectives on preventing the transition to injection drug use.

Kira Tozer, Despina Tzemis, Ashraf Amlani, Larissa Coser, Darlene Taylor, Natasha Van Borek, Elizabeth Saewyc, Jane A Buxton,

<h4>Background</h4>The Youth Injection Prevention (YIP) project aimed to identify factors associated with the prevention of transitioning to injection drug use (IDU) among street-involved youth (youth who had spent at least 3 consecutive nights without a fixed address or without their parents/caregivers in the previous six months) aged 16-24 years in ... Read more >>

BMC Public Health (BMC public health)
[2015, 15:800]

Cited: 4 times

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Self-Collected versus Clinician-Collected Sampling for Chlamydia and Gonorrhea Screening: A Systemic Review and Meta-Analysis.

Carole Lunny, Darlene Taylor, Linda Hoang, Tom Wong, Mark Gilbert, Richard Lester, Mel Krajden, Gina Ogilvie,

<h4>Background</h4>The increases in STI rates since the late 1990s in Canada have occurred despite widespread primary care and targeted public health programs and in the setting of universal health care. More innovative interventions are required that would eliminate barriers to STI testing such as internet-based or mail-in home and community ... Read more >>

PLoS One (PloS one)
[2015, 10(7):e0132776]

Cited: 52 times

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Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management.

Darlene K Taylor, Kristine Holthouser, James H Segars, Phyllis C Leppert,

Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female reproductive tract, but there are few non-surgical treatment options. Although many advances in the understanding of the molecular components of these tumors have occurred over the past five years, an effective pharmaceutical approach remains elusive. Further, there is ... Read more >>

F1000Res (F1000Research)
[2015, 4(F1000 Faculty Rev):183]

Cited: 8 times

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Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management

Darlene Taylor, Kristine Holthouser, James Segars, Phyllis Leppert,

Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female reproductive tract, but there are few non-surgical treatment options. Although many advances in the understanding of the molecular components of these tumors have occurred over the past five years, an effective pharmaceutical approach remains elusive. Further, there is ... Read more >>

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Cited: 2 times

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A cross-sectional survey exploring attitudes towards provincial electronic health record implementation among clients attending the Provincial Sexually Transmitted Infections Clinic in British Columbia.

Heather Pedersen, Darlene Taylor, Mark Gilbert, Melanie Achen, Richard Lester, Gina Ogilvie,

<h4>Introduction</h4>To support control of sexually transmitted infections (STI), British Columbia is exploring data sharing through a provincial electronic health record (EHR). Increased electronic data sharing among healthcare providers may be a barrier for clients of STI clinics where expectations of privacy and confidentiality are heightened.<h4>Methods</h4>A survey to assess attitudes towards ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2015, 91(1):44-48]

Cited: 2 times

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Probability of a false-negative HIV antibody test result during the window period: a tool for pre- and post-test counselling.

Darlene Taylor, Monica Durigon, Heather Davis, Chris Archibald, Bernhard Konrad, Daniel Coombs, Mark Gilbert, Darrel Cook, Mel Krajden, Tom Wong, Gina Ogilvie,

Failure to understand the risk of false-negative HIV test results during the window period results in anxiety. Patients typically want accurate test results as soon as possible while clinicians prefer to wait until the probability of a false-negative is virtually nil. This review summarizes the median window periods for third-generation ... Read more >>

Int J STD AIDS (International journal of STD & AIDS)
[2015, 26(4):215-224]

Cited: 19 times

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The effect of weekly text-message communication on treatment completion among patients with latent tuberculosis infection: study protocol for a randomised controlled trial (WelTel LTBI).

Mia L van der Kop, Jasmina Memetovic, Anik Patel, Fawziah Marra, Mohsen Sadatsafavi, Jan Hajek, Kirsten Smillie, Lehana Thabane, Darlene Taylor, James Johnston, Richard T Lester,

<h4>Introduction</h4>Interventions to improve adherence to treatment for latent tuberculosis infection (LTBI) are necessary to improve treatment completion rates and optimise tuberculosis (TB) control efforts. The high prevalence of cell phone use presents opportunities to develop innovative ways to engage patients in care. A randomised controlled trial (RCT), WelTel Kenya1, demonstrated ... Read more >>

BMJ Open (BMJ open)
[2014, 4(4):e004362]

Cited: 12 times

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Finding a voice: participatory research with street-involved youth in the youth injection prevention project.

Larissa Rodrigues Coser, Kira Tozer, Natasha Van Borek, Despina Tzemis, Darlene Taylor, Elizabeth Saewyc, Jane A Buxton,

This article uses a Positive Youth Development framework to explore the experiences of six experiential youth coresearchers (YCs) in the Youth Injection Prevention (YIP) participatory research project, and the parallel track process of empowerment and capacity building that developed. The YIP project was conducted in Metro Vancouver at the BC ... Read more >>

Health Promot Pract (Health promotion practice)
[2014, 15(5):732-738]

Cited: 8 times

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Short message service (SMS) interventions for the prevention and treatment of sexually transmitted infections: a systematic review protocol.

Carole Lunny, Darlene Taylor, Jasmina Memetovic, Orion Wärje, Richard Lester, Tom Wong, Kendall Ho, Mark Gilbert, Gina Ogilvie,

<h4>Background</h4>Globally, the incidence of sexually transmitted infections (STI) is rising, posing a challenge to its control and appropriate management. Text messaging has become the most common mode of communication among almost six billion mobile phone users worldwide. Text messaging can be used to remind patients about clinic appointments, to notify ... Read more >>

Syst Rev (Systematic reviews)
[2014, 3:7]

Cited: 13 times

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Factors associated with intention to use internet-based testing for sexually transmitted infections among men who have sex with men.

Mark Gilbert, Travis Salway Hottes, Thomas Kerr, Darlene Taylor, Christopher K Fairley, Richard Lester, Tom Wong, Terry Trussler, Rick Marchand, Jean Shoveller, Gina Ogilvie,

<h4>Background</h4>Internet-based testing programs are being increasingly used to reduce testing barriers for individuals at higher risk of infection, yet the population impact and potential for exacerbation of existing health inequities of these programs are not well understood.<h4>Objective</h4>We used a large online sample of men who have sex with men (MSM) ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2013, 15(11):e254]

Cited: 26 times

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A brief tool to assess capacity to consent for medical care among homeless individuals with problematic substance use: study protocol.

Darlene Taylor, Louise Masse, Anita Ho, Michael L Rekart, Mark Tyndall, Bonnie Henry, Joanne Clifton, Laurenna Peters, Gina Ogilvie, Jane Buxton,

<h4>Background</h4>Public health care increasingly uses outreach models to engage individuals who are marginalized, many of whom misuse substances. Problematic substance use, together with marginalization from the health care system, among homeless adults makes it difficult to assess their capacity to consent to medical care. Tools have been developed to assess ... Read more >>

Arch Public Health (Archives of public health = Archives belges de sante publique)
[2013, 71(1):11]

Cited: 0 times

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Soluble reduced graphene oxide sheets grafted with polypyridylruthenium-derivatized polystyrene brushes as light harvesting antenna for photovoltaic applications.

Zhen Fang, Akitaka Ito, Andrew C Stuart, Hanlin Luo, Zuofeng Chen, Kizhanipuram Vinodgopal, Wei You, Thomas J Meyer, Darlene K Taylor,

Soluble graphene nanosheets, prepared by grafting polystyrene-based polymer chains from the surface of reduced graphene oxide (RGO), have been functionalized with pendant Ru(II) polypyridine chromophores. N-Hydroxysuccinimide (NHS) derivatized p-vinylbenzoic acid polymer chains were grown from methyl bromoisobutyrate initiation sites on the surface of RGO by atom transfer radical polymerization (ATRP). ... Read more >>

ACS Nano (ACS nano)
[2013, 7(9):7992-8002]

Cited: 10 times

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Self-collected versus clinician-collected sampling for sexually transmitted infections: a systematic review and meta-analysis protocol.

Darlene Taylor, Carole Lunny, Tom Wong, Mark Gilbert, Neville Li, Richard Lester, Mel Krajden, Linda Hoang, Gina Ogilvie,

<h4>Background</h4>Three meta-analyses and one systematic review have been conducted on the question of whether self-collected specimens are as accurate as clinician-collected specimens for STI screening. However, these reviews predate 2007 and did not analyze rectal or pharyngeal collection sites. Currently, there is no consensus on which sampling method is the ... Read more >>

Syst Rev (Systematic reviews)
[2013, 2:93]

Cited: 6 times

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Atom transfer radical polymerization preparation and photophysical properties of polypyridylruthenium derivatized polystyrenes.

Zhen Fang, Akitaka Ito, Shahar Keinan, Zuofeng Chen, Zoe Watson, Jason Rochette, Yosuke Kanai, Darlene Taylor, Kirk S Schanze, Thomas J Meyer,

A ruthenium containing polymer featuring a short carbonyl-amino-methylene linker has been prepared by atom transfer radical polymerization (ATRP). The polymer was derived from ATRP of the N-hydroxysuccinimide (NHS) derivative of p-vinylbenzoic acid, followed by an amide coupling reaction of the NHS-polystyrene with Ru(II) complexes derivatized with aminomethyl groups (i.e., [Ru(bpy)2(CH3-bpy-CH2NH2)](2+) ... Read more >>

Inorg Chem (Inorganic chemistry)
[2013, 52(15):8511-8520]

Cited: 8 times

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