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Author Daren K Heyland

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Relationship Between Nutrition Intake and Outcome After Subarachnoid Hemorrhage: Results From the International Nutritional Survey.

Neeraj Badjatia, Alice Ryan, H Alex Choi, Gunjan Y Parikh, Xuran Jiang, Andrew G Day, Daren K Heyland,

<h4>Background</h4>A previous study suggested an association between low caloric intake(CI), negative nitrogen balance, and poor outcome after subarachnoid hemorrhage(SAH). Objective of this multinational, multicenter study was to investigate whether clinical outcomes vary by protein intake(PI) or CI in SAH patients adjusting for the nutritional risk as judged by the modified ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, 36(10):1141-1148]

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A catalogue of tools and variables from crisis and routine care to support decision-making about allocation of intensive care beds and ventilator treatment during pandemics: Scoping review.

Magnolia Cardona, Claudia C Dobler, Eyza Koreshe, Daren K Heyland, Rebecca H Nguyen, Joan P Y Sim, Justin Clark, Alex Psirides,

<h4>Purpose</h4>This scoping review sought to identify objective factors to assist clinicians and policy-makers in making consistent, objective and ethically sound decisions about resource allocation when healthcare rationing is inevitable.<h4>Materials and methods</h4>Review of guidelines and tools used in ICUs, hospital wards and emergency departments on how to best allocate intensive care ... Read more >>

J Crit Care (Journal of critical care)
[2021, 66:33-43]

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Correlation between gastric residual volumes and markers of gastric emptying: A post hoc analysis of a randomized clinical trial.

Charles Chin Han Lew, Zheng-Yii Lee, Andrew G Day, Daren K Heyland,

<h4>Background</h4>The correlation between gastric residual volumes (GRVs) and markers of gastric emptying (GE) in critically ill patients is unclear. This particularly applies to critically ill surgical patients, as they are underrepresented in previous studies.<h4>Methods</h4>We conducted a post hoc analysis of a multicenter trial that investigated the effectiveness of a promotility ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2021, :]

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The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials.

Zheng-Yii Lee, Cindy Sing Ling Yap, M Shahnaz Hasan, Julia Patrick Engkasan, Mohd Yusof Barakatun-Nisak, Andrew G Day, Jayshil J Patel, Daren K Heyland,

<h4>Background</h4>The optimal protein dose in critical illness is unknown. We aim to conduct a systematic review of randomized controlled trials (RCTs) to compare the effect of higher versus lower protein delivery (with similar energy delivery between groups) on clinical and patient-centered outcomes in critically ill patients.<h4>Methods</h4>We searched MEDLINE, EMBASE, CENTRAL ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):260]

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Randomised trial of a serious illness decision aid (Plan Well Guide) for patients and their substitute decision-makers to improve engagement in advance care planning.

Michelle Howard, Dawn Elston, Sayem Borhan, Abe Hafid, Neha Arora, Ruth Forbes, Carrie Bernard, Daren K Heyland,

<h4>Objective</h4>To evaluate the feasibility and efficacy of a serious illness decision aid (Plan Well Guide) in increasing the engagement of substitute decision-makers (SDM) in advance care planning (ACP).<h4>Methods</h4>This trial was conducted (2017-2019) in outpatient settings in Ontario, Canada, aiming to recruit 90 dyads of patients aged 65 years and older ... Read more >>

BMJ Support Palliat Care (BMJ supportive & palliative care)
[2021, :]

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Initial development and validation of a novel nutrition risk, sarcopenia, and frailty assessment tool in mechanically ventilated critically ill patients: The NUTRIC-SF score.

Zheng-Yii Lee, M Shahnaz Hasan, Andrew G Day, Ching Choe Ng, Su Ping Ong, Cindy Sing Ling Yap, Julia Patrick Engkasan, Mohd Yusof Barakatun-Nisak, Daren K Heyland,

<h4>Background</h4>Nutrition risk, sarcopenia, and frailty are interrelated. They may be due to suboptimal or prevented by optimal nutrition intake. The combination of nutrition risk (modified nutrition risk in the critically ill [mNUTRIC]), sarcopenia (SARC-F combined with calf circumference [SARC-CALF]), and frailty (clinical frailty scale [CFS]) in a single score may ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2021, :]

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Validation of the modified NUTrition Risk Score (mNUTRIC) in mechanically ventilated, severe burn patients: A prospective multinational cohort study.

L Alfonso Ortiz, Xuran Jiang, Alexis F Turgeon, Lucy Wibbenmeyer, Jonathan Pollack, Samuel P Mandell, Andrew G Day, Daren K Heyland,

<h4>Background</h4>Whether nutrition therapy benefits all burn victims equally is unknown. To identify patients who will benefit the most from optimal nutrition, the modified Nutrition Risk in Critically Ill (mNUTRIC) Score has been validated in the Intensive Care Unit. However, the utility of mNUTRIC in severe burn victims is unknown. We ... Read more >>

Burns (Burns : journal of the International Society for Burn Injuries)
[2021, :]

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Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness.

Matthew F Mart, Timothy D Girard, Jennifer L Thompson, Hannah Whitten-Vile, Rameela Raman, Pratik P Pandharipande, Daren K Heyland, E Wesley Ely, Nathan E Brummel,

<h4>Background and aims</h4>Risk factors for poor outcomes after critical illness are incompletely understood. While nutritional risk is associated with mortality in critically ill patients, its association with disability, cognitive, and health-related quality of life is unclear in survivors of critical illness. This study's objective was to determine whether greater nutritional ... Read more >>

Clin Nutr (Clinical nutrition (Edinburgh, Scotland))
[2021, 40(6):3868-3874]

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Combination of enteral and parenteral nutrition in the acute phase of critical illness: An updated systematic review and meta-analysis.

Aileen Hill, Daren K Heyland, Luis A Ortiz Reyes, Elena Laaf, Sebastian Wendt, Gunnar Elke, Christian Stoppe,

<h4>Background</h4>Uncertainty remains about the best route and timing of medical nutrition therapy in the acute phase of critical illness. Early combined enteral nutrition (EN) and parenteral nutrition (PN) may represent an attractive option to achieve recommended energy and protein goals in select patient groups. This meta-analysis aims to update and ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2021, :]

Cited: 1 time

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Translation and adaptation of the modified NUTRIC score for critically ill patients.

Zeinab Javid, Niyaz Mohammad Zadeh Honarvar, Majid Khadem-Rezaiyan, Daren K Heyland, Mahdi Shadnoush, Seyed Hossein Ardehali, Shadi Khalili Lashkami, Vahid Maleki,

<h4>Background & aims</h4>Some critically ill patients are at high nutritional risk, and early identification of these patients is needed to reduce morbidity and mortality related to underfeeding. The Modified NUTrition Risk in Critically ill (mNUTRIC) score is the first nutritional risk assessment tool developed and validated specifically for ICU patients. ... Read more >>

Clin Nutr ESPEN (Clinical nutrition ESPEN)
[2021, 43:348-352]

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Determining the psychometric properties of a novel questionnaire to measure "preparedness for the future" (Prep FQ).

Daren K Heyland, J Paige Pope, Xuran Jiang, Andrew G Day,

<h4>Background</h4>People are living longer than ever before. However, with living longer comes increased problems that negatively impact on quality of life and the quality of death. Tools are needed to help individuals assess whether they are practicing the best attitudes and behaviors that are associated with a future long life, ... Read more >>

Health Qual Life Outcomes (Health and quality of life outcomes)
[2021, 19(1):122]

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Challenges and facilitators in delivering optimal care at the End of Life for older patients: a scoping review on the clinicians' perspective.

Samantha Fien, Emily Plunkett, Claudia Fien, Sally Greenaway, Daren K Heyland, Justin Clark, Magnolia Cardona,

The concepts and elements determining quality of care at the End of Life may vary across professional groups but there is consensus that high-quality care at the End of Life is beneficial for the patient, families, health systems and society at large. This scoping review aimed to elucidate gaps in ... Read more >>

Aging Clin Exp Res (Aging clinical and experimental research)
[2021, :]

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Randomized Controlled Trial of a Decision Support Intervention About Cardiopulmonary Resuscitation for Hospitalized Patients Who Have a High Risk of Death.

Daniel Kobewka, Daren K Heyland, Peter Dodek, Aman Nijjar, Nick Bansback, Michelle Howard, Peter Munene, Elizabeth Kunkel, Alan Forster, Jamie Brehaut, John J You,

<h4>Background</h4>Many seriously ill hospitalized patients have cardiopulmonary resuscitation (CPR) as part of their care plan, but CPR is unlikely to achieve the goals of many seriously ill hospitalized patients.<h4>Objective</h4>To determine if a multicomponent decision support intervention changes documented orders for CPR in the medical record, compared to usual care.<h4>Design</h4>Open-label randomized ... Read more >>

J Gen Intern Med (Journal of general internal medicine)
[2021, 36(9):2593-2600]

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Correction: Hill, A.; et al. Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis. Nutrients 2019, 11, 2103.

Aileen Hill, Kai C Clasen, Sebastian Wendt, Ádám G Majoros, Christian Stoppe, Neill Kj Adhikari, Daren K Heyland, Carina Benstoem,

The authors thank the readers for pointing out the issues [...]. ... Read more >>

Nutrients (Nutrients)
[2020, 12(12):]

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Impact of malnutrition on survival in adult patients after elective cardiac surgery: Long-term follow up data.

Sergey M Efremov, Tatiana I Ionova, Tatiana P Nikitina, Pavel E Vedernikov, Timur A Dzhumatov, Timofey S Ovchinnikov, Abduvahhob A Rashidov, Alexandr E Khomenko, Christian Stoppe, Daren K Heyland, Vladimir V Lomivorotov,

The data article refers to the paper titles "Impact of malnutrition on long-term survival in adult patients after elective cardiac surgery" [1]. The data refer to the analysis of the relationship between baseline malnutrition and long-term mortality after cardiac surgery. Baseline demographic, nutritional, and medical history data were collected for ... Read more >>

Data Brief (Data in brief)
[2021, 34:106651]

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Longitudinal Outcomes in Octogenarian Critically Ill Patients with a Focus on Frailty and Cardiac Surgery.

Aileen Hill, Daren K Heyland, Rolf Rossaint, Rakesh C Arora, Daniel T Engelman, Andrew G Day, Christian Stoppe,

Cardiac surgery (CSX) can be lifesaving in elderly patients (age ≥ 80 years) but may still be associated with complications and functional decline. Frailty represents a determinant to outcomes in critically ill patients, but little is known about its influence on elderly CSX-patients. This is a secondary exploratory analysis of ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 10(1):]

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Incidence, Risk Factors, and Clinical Consequence of Enteral Feeding Intolerance in the Mechanically Ventilated Critically Ill: An Analysis of a Multicenter, Multiyear Database.

Daren K Heyland, Alfonso Ortiz, Christian Stoppe, Jayshil J Patel, D Dante Yeh, George Dukes, Yaozhu J Chen, Cristina Almansa, Andrew G Day,

<h4>Objectives</h4>To determine the incidence of enteral feed intolerance, identify factors associated with enteral feed intolerance, and assess the relationship between enteral feed intolerance and key nutritional and clinical outcomes in critically ill patients.<h4>Design</h4>Analysis of International Nutrition Survey database collected prospectively from 2007 to 2014.<h4>Setting</h4>Seven-hundred eighty-five ICUs from around the world.<h4>Patients</h4>Mechanically ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(1):49-59]

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Application of the modified Nutrition Risk in Critically Ill score to nutritional risk stratification of trauma victims: A multicenter observational study.

Chinenye Iwuchukwu, Grant E O'Keefe, Andrew G Day, Xuran Jiang, Daren K Heyland,

<h4>Background</h4>The modified Nutrition Risk in Critically Ill (mNUTRIC) score was developed to identify patients most likely to benefit from nutritional therapies and to stratify or select study subjects for clinical trials. The score is not validated in trauma victims in whom adequate nutritional support is important and difficult to achieve. ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2020, 89(6):1143-1148]

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Effect of "Speak Up" educational tools to engage patients in advance care planning in outpatient healthcare settings: A prospective before-after study.

Michelle Howard, Carole A Robinson, Michael McKenzie, Gillian Fyles, Louise Hanvey, Doris Barwich, Carrie Bernard, Dawn Elston, Amy Tan, Lorenz Yeung, Daren K Heyland,

<h4>Background</h4>Tools for advance care planning (ACP) are advocated to help ensure patient values guide healthcare decisions. Evaluation of the effect of tools introduced to patients in clinical settings is needed.<h4>Objective</h4>To evaluate the effect of the Canadian Speak Up Campaign tools on engagement in advance care planning (ACP), with patients attending ... Read more >>

Patient Educ Couns (Patient education and counseling)
[2021, 104(4):709-714]

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Effects of malnutrition on long-term survival in adult patients after elective cardiac surgery.

Sergey M Efremov, Tatiana I Ionova, Tatiana P Nikitina, Pavel E Vedernikov, Timur A Dzhumatov, Timofey S Ovchinnikov, Abduvahhob A Rashidov, Christian Stoppe, Daren K Heyland, Vladimir V Lomivorotov,

<h4>Objectives</h4>The aim of this study was to investigate the relationship between malnutrition and long-term survival in patients who underwent cardiopulmonary bypass (CPB).<h4>Methods</h4>This study analyzed the long-term survival data of a mixed cohort of 1187 cardiac patients previously enrolled in a prospective observational study of nutritional screening in cardiac surgery. Nutritional ... Read more >>

Nutrition (Nutrition (Burbank, Los Angeles County, Calif.))
[2021, 83:111057]

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Supporting decision-making on allocation of ICU beds and ventilators in pandemics

Magnolia Cardona, Claudia Dobler, Eyza Koreshe, Daren Heyland, Rebecca Nguyen, Joan P.Y. Sim, Justin Clark, Alex Psirides,

As the world struggles with the COVID-19 pandemic, health service demands have increased to a point where healthcare resources may prove inadequate to meet demand. Guidelines and tools on how to best allocate intensive care beds and ventilators developed during previous epidemics can assist clinicians and policy-makers to make consistent, ... Read more >>

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Validity and Reliability of a Thai Version of Family Satisfaction with Care in the Intensive Care Unit Survey.

Pattraporn Tajarernmuang, Kaweesak Chittawatanarat, Peter Dodek, Daren K Heyland, Panida Chanayat, Juthamas Inchai, Chaicharn Pothirat, Chalerm Liwsrisakun, Chaiwat Bumroongkit, Athavuth Deesomchok, Theerakorn Theerakittikul, Atikun Limsukon,

<h4>Purpose</h4>To examine reliability and validity of a Thai version of the Family Satisfaction with Intensive Care Unit (FS-ICU 24) questionnaire and use this survey in intensive care units (ICUs) in Thailand.<h4>Materials and methods</h4>The standard English FS-ICU questionnaire was translated into the Thai language using translation and culture adaptation guidelines. After ... Read more >>

Indian J Crit Care Med (Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine)
[2020, 24(10):946-954]

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The initial validation of a novel outcome measure in severe burns- the Persistent Organ Dysfunction +Death: Results from a multicenter evaluation.

Christian Stoppe, Aileen Hill, Andrew G Day, Arnold S Kristof, Gabriel Hundeshagen, Ulrich Kneser, Justus Beier, David Lumenta, Bong-Sung Kim, Jan Plock, Declan P Collins, Jochen Gille, Xuran Jiang, Daren K Heyland,

<h4>Introduction</h4>A need exists to improve the efficiency of clinical trials in burn care. The objective of this study was to validate "Persistent Organ Dysfunction" plus death as endpoint in burn patients and to demonstrate its statistical efficiency.<h4>Methods</h4>This secondary outcome analysis of a dataset from a prospective international multicenter RCT (RE-ENERGIZE) ... Read more >>

Burns (Burns : journal of the International Society for Burn Injuries)
[2021, 47(4):765-775]

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Association between ultrasound quadriceps muscle status with premorbid functional status and 60-day mortality in mechanically ventilated critically ill patient: A single-center prospective observational study.

Zheng-Yii Lee, Su Ping Ong, Ching Choe Ng, Cindy Sing Ling Yap, Julia Patrick Engkasan, Mohd Yusof Barakatun-Nisak, Daren K Heyland, M Shahnaz Hasan,

<h4>Background & aims</h4>In critically ill patients, direct measurement of skeletal muscle using bedside ultrasound (US) may identify a patient population that might benefit more from optimal nutrition practices. When US is not available, survey measures of nutrition risk and functional status that are associated with muscle status may be used ... Read more >>

Clin Nutr (Clinical nutrition (Edinburgh, Scotland))
[2021, 40(3):1338-1347]

Cited: 4 times

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Commentary: Nutrition Support After Cardiac Surgery - How to Dine?

Aileen Hill, Daren K Heyland, Christian Stoppe,

Semin Thorac Cardiovasc Surg (Seminars in thoracic and cardiovascular surgery)
[2021, 33(1):118-120]

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