Full Text Journal Articles by
Author Dante A Suffredini

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The Long Road to Normalcy Following Survival From COVID-19-Associated Acute Respiratory Distress Syndrome.

Dante A Suffredini,

Crit Care Med (Critical care medicine)
[2021, 49(11):1996-1999]

Cited: 0 times

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Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis.

Ahmad Al-Abdouh, Sadam Haddadin, Atul Matta, Ahmad Jabri, Mahmoud Barbarawi, Waiel Abusnina, Qais Radideh, Mohammed Mhanna, Dante A Suffredini, Erin D Michos,

<h4>Purpose</h4>To evaluate the efficacy and safety of midodrine use in intensive care units (ICU) to facilitate weaning off intravenous vasopressors (IVV).<h4>Methods</h4>We searched PubMed/MEDLINE, Cochrane library, and Google Scholar (inception through October 18<sup>th</sup>, 2020) for studies evaluating adjuvant use of midodrine to IVV in the ICU. The outcomes of interest were ... Read more >>

Crit Care Res Pract (Critical care research and practice)
[2021, 2021:5588483]

Cited: 0 times

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Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan.

Yan Li, Xizhong Cui, Joseph Shiloach, Jeffrey Wang, Dante A Suffredini, Wanying Xu, Wancang Liu, Yvonne Fitz, Junfeng Sun, Peter Q Eichacker,

<h4>Background</h4>Lethal B. anthracis infection produces high proinflammatory peptidoglycan (PGN) burdens in hosts. We investigated whether the lethality and inflammation anthrax PGN can produce are related.<h4>Methods</h4>At 6 h before and the start of 24 h anthrax PGN infusions, rats (n = 198) were treated with diluent (controls) or one of three IV-doses of either hydrocortisone ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2020, 8(1):67]

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Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab.

Dante A Suffredini, Jung-Min Lee, Cody J Peer, Drew Pratt, David E Kleiner, Jason M Elinoff, Michael A Solomon,

<h4>Background</h4>Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare cause of pulmonary hypertension that is associated with malignancies and is marked by the presence of non-occlusive tumor emboli and fibrocellular intimal proliferation of small pulmonary arteries leading to increased pulmonary vascular resistance and right heart failure. The diagnosis of PTTM is ... Read more >>

BMC Pulm Med (BMC pulmonary medicine)
[2018, 18(1):112]

Cited: 3 times

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Management of Antiretrovirals in Critically Ill Patients: Great Progress But Potential Pitfalls.

Dante A Suffredini, Jomy M George, Henry Masur,

Crit Care Med (Critical care medicine)
[2018, 46(5):663-665]

Cited: 1 time

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Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support.

Dante A Suffredini, Xizhong Cui, Dharmvir Jaswal, Kenneth E Remy, Yan Li, Junfeng Sun, Steven B Solomon, Yvonne Fitz, Mahtab Moayeri, Stephen Leppla, Peter Q Eichacker,

BACKGROUND:Although anthrax immune globulin (AIG) improved survival in antibiotic-treated Bacillus anthracis-challenged animal models, whether it adds to the benefit of conventional hemodynamic support for B. anthracis toxin-associated shock is unknown. METHODS:We therefore tested AIG in sedated, mechanically ventilated canines challenged with 24-h B. anthracis lethal and edema toxin infusions and ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2017, 5(1):48]

Cited: 1 time

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Shock and lethality with anthrax edema toxin in rats are associated with reduced arterial responsiveness to phenylephrine and are reversed with adefovir.

Dante A Suffredini, Yan Li, Wanying Xu, Mahtab Moayeri, Stephen Leppla, Yvonne Fitz, Xizhong Cui, Peter Q Eichacker,

Although edema toxin (ETx) and lethal toxin (LTx) contribute to <i>Bacillus anthracis</i> shock and lethality, the mechanisms underlying their cardiovascular effects are unclear. We have previously shown that ETx but not LTx inhibited phenylephrine-stimulated contraction of aortic rings prepared from healthy rats and that adefovir, a selective inhibitor of ETx ... Read more >>

Am J Physiol Heart Circ Physiol (American journal of physiology. Heart and circulatory physiology)
[2017, 313(5):H946-H958]

Cited: 3 times

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Parenteral irons versus transfused red blood cells for treatment of anemia during canine experimental bacterial pneumonia.

Dante A Suffredini, Wanying Xu, Junfeng Sun, Jesús Barea-Mendoza, Steven B Solomon, Samuel L Brashears, Andreas Perlegas, Daniel B Kim-Shapiro, Harvey G Klein, Charles Natanson, Irene Cortés-Puch,

<h4>Background</h4>No studies have been performed comparing intravenous (IV) iron with transfused red blood cells (RBCs) for treating anemia during infection. In a previous report, transfused older RBCs increased free iron release and mortality in infected animals when compared to fresher cells. We hypothesized that treating anemia during infection with transfused ... Read more >>

Transfusion (Transfusion)
[2017, 57(10):2338-2347]

Cited: 7 times

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Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies.

Dante A Suffredini, Hanish Sampath-Kumar, Yan Li, Lernik Ohanjanian, Kenneth E Remy, Xizhong Cui, Peter Q Eichacker,

The US outbreak of B.anthracis infection in 2001 and subsequent cases in the US and Europe demonstrate that anthrax is a continuing risk for the developed world. While several bacterial components contribute to the pathogenesis of B. anthracis, production of lethal toxin (LT) is strongly associated with the development of ... Read more >>

Toxins (Basel) (Toxins)
[2015, 7(12):5417-5434]

Cited: 6 times

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Long-term outcomes following alemtuzumab induction in lung transplantation.

Brody Wehman, Bartley P Griffith, Akshu Balwan, Zachary N Kon, Dante A Suffredini, Charles Evans, Jose P Garcia, Aldo Iacono,

<h4>Objectives</h4>Alemtuzumab is a commonly used induction agent for solid-organ transplantation. Its use in lung transplantation with reduced immunosuppressive regimens, however, has yet to be well characterized.<h4>Methods</h4>From November 2006 to March 2008, 20 consecutive lung transplantation patients received alemtuzumab induction with a reduced maintenance immunosuppression regimen. Twenty consecutive case-controls who underwent ... Read more >>

Heart Surg Forum (The heart surgery forum)
[2013, 16(5):E252-6]

Cited: 3 times

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At the twisted heart of nicotine addiction.

Dante A Suffredini, Robert Michael Reed,

This case report reviews the ECG manifestations of chronic obstructive pulmonary disease (COPD). Distinct changes of the P-wave axis, QRS axis and morphology are a direct result of the pathophysiological and anatomical changes associated with COPD. These changes are illustrated in a patient with a history of COPD presenting with ... Read more >>

BMJ Case Rep (BMJ case reports)
[2012, 2012:]

Cited: 0 times

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Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells.

Takehito Igarashi, Jason Wynberg, Ramprasad Srinivasan, Brian Becknell, J Phillip McCoy, Yoshiyuki Takahashi, Dante A Suffredini, W Marston Linehan, Michael A Caligiuri, Richard W Childs,

Cellular inactivation through killer immunoglobulin-like receptors (KIRs) may allow neoplastic cells to evade host natural killer (NK) cell-mediated immunity. Recently, alloreactive NK cells were shown to mediate antileukemic effects against acute myelogenous leukemia (AML) after mismatched transplantation, when KIR ligand incompatibility existed in the direction of graft-versus-host disease (GVHD). Therefore, ... Read more >>

Blood (Blood)
[2004, 104(1):170-177]

Cited: 97 times

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