Full Text Journal Articles by
Author Danielle Shaked

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Vitamin D, Folate, and Cobalamin Serum Concentrations Are Related to Brain Volume and White Matter Integrity in Urban Adults.

May A Beydoun, Danielle Shaked, Sharmin Hossain, Hind A Beydoun, Leslie I Katzel, Christos Davatzikos, Rao P Gullapalli, Stephen L Seliger, Guray Erus, Michele K Evans, Alan B Zonderman, Shari R Waldstein,

Background and objectives: Lower vitamin status has been linked to cognitive deficits, pending mechanistic elucidation. Serum 25-hydroxyvitamin D [25(OH)D], folate and cobalamin were explored against brain volumes and white matter integrity (WMI). Methods: Three prospective waves from Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) study were ... Read more >>

Front Aging Neurosci (Frontiers in aging neuroscience)
[2020, 12:140]

Cited: 0 times

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Accelerated epigenetic age and cognitive decline among urban-dwelling adults.

May A Beydoun, Danielle Shaked, Salman M Tajuddin, Jordan Weiss, Michele K Evans, Alan B Zonderman,

OBJECTIVES:Epigenetic modifications are closely linked with aging, but their relationship with cognition remains equivocal. Given known sex differences in epigenetic aging, we explored sex-specific associations of 3 DNA methylation (DNAm)-based measures of epigenetic age acceleration (EAA) with baseline and longitudinal change in cognitive performance among middle-aged urban adults. METHODS:We used ... Read more >>

Neurology (Neurology)
[2020, 94(6):e613-e625]

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Red Cell Distribution Width Is Directly Associated with Poor Cognitive Performance among Nonanemic, Middle-Aged, Urban Adults.

May A Beydoun, Sharmin Hossain, Hind A Beydoun, Danielle Shaked, Jordan Weiss, Michele K Evans, Alan B Zonderman,

BACKGROUND:Epidemiological evidence suggests that both anemia and elevated red cell distribution width (RDW) are associated with cognitive impairment. However, the interplay between these 2 predictors has been understudied. OBJECTIVES:We examined sex- and anemia-specific associations between RDW and cognitive performance among urban adults in the United States. METHODS:Data from the Healthy ... Read more >>

J. Nutr. (The Journal of nutrition)
[2020, 150(1):128-139]

Cited: 0 times

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Modification of everyday activities and its association with self-awareness in cognitively diverse older adults.

Danielle Shaked, Preeti Sunderaraman, Jennifer Piscitello, Sarah Cines, Christiane Hale, Davangere Devanand, Jason Karlawish, Stephanie Cosentino,

Cognitive impairment (CI) in older adults is frequently accompanied by difficulty performing complex everyday activities (e.g., managing finances). However, it is unclear if and how older adults with CI modify their activities (i.e., Do individuals continue, monitor, seek help with, change their approach to, or stop different activities?). In the ... Read more >>

PLoS ONE (PloS one)
[2019, 14(11):e0222769]

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Telomere length and cognitive function: Differential patterns across sociodemographic groups.

Daniel K Leibel, Danielle Shaked, Danielle L Beatty Moody, Hans B Liu, Nan-Ping Weng, Michele K Evans, Alan B Zonderman, Shari R Waldstein,

OBJECTIVE:The present study investigates whether associations between telomere length (TL) and cognitive performance across multiple domains are moderated by poverty status and race. METHOD:Participants were 325 African American and White urban-dwelling adults (M age = 47.9 years; 49.5% African American; 50.2% female; 48.9% living in poverty) from the Healthy Aging ... Read more >>

Neuropsychology (Neuropsychology)
[2020, 34(2):186-198]

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Disparities in Diffuse Cortical White Matter Integrity Between Socioeconomic Groups.

Danielle Shaked, Daniel K Leibel, Leslie I Katzel, Christos Davatzikos, Rao P Gullapalli, Stephen L Seliger, Guray Erus, Michele K Evans, Alan B Zonderman, Shari R Waldstein,

There is a growing literature demonstrating a link between lower socioeconomic status (SES) and poorer neuroanatomical health, such as smaller total and regional gray and white matter volumes, as well as greater white matter lesion volumes. Little is known, however, about the relation between SES and white matter integrity. Here ... Read more >>

(Frontiers in human neuroscience)
[2019, 13:198]

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One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.

May A Beydoun, Salman M Tajuddin, Danielle Shaked, Hind A Beydoun, Michele K Evans, Alan B Zonderman,

The sex-specific link between longitudinal annual rate of cognitive change (LARCC) and polymorphisms in one-carbon metabolism enzymatic genes remains unclear, particularly among African-American adults. We tested associations of 14 single nucleotide polymorphisms (SNPs) from MTHFR, MTRR, MTR, and SHMT genes and select MTHFR haplotypes and latent classes (SNPHAP/SNPLC) with LARCC. ... Read more >>

Neurobiol. Aging (Neurobiology of aging)
[2019, 84:238.e5-238.e18]

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Sociodemographic disparities in corticolimbic structures.

Danielle Shaked, Zachary B Millman, Danielle L Beatty Moody, William F Rosenberger, Hui Shao, Leslie I Katzel, Christos Davatzikos, Rao P Gullapalli, Stephen L Seliger, Guray Erus, Michele K Evans, Alan B Zonderman, Shari R Waldstein,

This study sought to examine the interactive relations of socioeconomic status and race to corticolimbic regions that may play a key role in translating stress to the poor health outcomes overrepresented among those of lower socioeconomic status and African American race. Participants were 200 community-dwelling, self-identified African American and White ... Read more >>

PLoS One (PloS one)
[2019, 14(5):e0216338]

Cited: 2 times

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Reliability and validity of the Conners' Continuous Performance Test.

Danielle Shaked, Lauren M D Faulkner, Kathryn Tolle, Carrington R Wendell, Shari R Waldstein, Robert J Spencer,

The Conners' Continuous Performance Test-Second Edition (CCPT-2) is a widely used measure of attention and impulsivity, however, only a minimal amount is known about its reliability. To clarify the psychometric properties of the CCPT-2, we assessed its performance stability and related it to criterion measures. A total of 91 undergraduate ... Read more >>

Appl Neuropsychol Adult (Applied neuropsychology. Adult)
[2020, 27(5):478-487]

Cited: 1 time

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Dorsolateral prefrontal cortex volume as a mediator between socioeconomic status and executive function.

Danielle Shaked, Leslie I Katzel, Stephen L Seliger, Rao P Gullapalli, Christos Davatzikos, Guray Erus, Michele K Evans, Alan B Zonderman, Shari R Waldstein,

OBJECTIVE:Lower socioeconomic status (SES) is related to poorer cognitive performance, but the neural underpinnings of this relation are not fully understood. This study examined whether SES-linked decrements in executive function were mediated by smaller dorsolateral prefrontal cortex (DLPFC) volumes. Given the literature demonstrating that SES-brain relations differ by race, we ... Read more >>

Neuropsychology (Neuropsychology)
[2018, 32(8):985-995]

Cited: 4 times

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Trends, Predictors, and Outcomes of Healthcare Resources Used in Patients Hospitalized with Alzheimer's Disease with at Least One Procedure: The Nationwide Inpatient Sample.

May A Beydoun, Alyssa A Gamaldo, Hind A Beydoun, Danielle Shaked, Alan B Zonderman, Shaker M Eid,

We assessed trends, predictors and outcomes of resource utilization in hospital inpatient discharges with a principal diagnosis of Alzheimer's disease (AD) with at least one procedure. Using Nationwide Inpatient Sample data (NIS, 2002-2012), discharges primarily diagnosed with AD, aged ≥60 y and with ≥1 procedure, were selected (Weighted N = 92,300). Hospital ... Read more >>

J Alzheimers Dis (Journal of Alzheimer's disease : JAD)
[2017, 57(3):813-824]

Cited: 0 times

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Sex, Race, and Socioeconomic Disparities in Patients With Aortic Stenosis (from a Nationwide Inpatient Sample).

Hind A Beydoun, May A Beydoun, Hailun Liang, Greg A Dore, Danielle Shaked, Alan B Zonderman, Shaker M Eid,

Aortic stenosis (AS) is the third most prevalent cardiovascular disease following hypertension and coronary artery disease. The primary objective of this cross-sectional study is to examine gender, racial, and socioeconomic disparities in AS-related health care utilization in patients aged ≥50 years using data from the Healthcare Cost and Utilization Project ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2016, 118(6):860-865]

Cited: 4 times

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Indicators of subjective social status: Differential associations across race and sex.

Danielle Shaked, Megan Williams, Michele K Evans, Alan B Zonderman,

Background:Subjective social status (SSS), or perception of rank on the social hierarchy, is an important indicator of various health outcomes. However, the psychosocial influences on this construct are unclear, and how these influences vary across different sociodemographic groups is poorly understood. Methods:Participants were 2077 African-American and Whites (M age=47.85; 57% ... Read more >>

(SSM - population health)
[2016, 2:700-707]

Cited: 7 times

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Alternative Pathway Analyses Indicate Bidirectional Relations between Depressive Symptoms, Diet Quality, and Central Adiposity in a Sample of Urban US Adults.

May A Beydoun, Marie T Fanelli-Kuczmarski, Danielle Shaked, Greg A Dore, Hind A Beydoun, Ola S Rostant, Michele K Evans, Alan B Zonderman,

Temporality between socioeconomic status (SES), depressive symptoms (DS), dietary quality (DQ), and central adiposity (CA) is underexplored.Alternative pathways linking SES to DQ, DS, and CA were tested and models compared, stratified by race and sex.With the use of data from the Healthy Aging in Neighborhoods of Diversity across the Life ... Read more >>

J. Nutr. (The Journal of nutrition)
[2016, 146(6):1241-1249]

Cited: 6 times

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The right insula contributes to memory awareness in cognitively diverse older adults.

Stephanie Cosentino, Adam M Brickman, Erica Griffith, Christian Habeck, Sarah Cines, Meagan Farrell, Danielle Shaked, Edward D Huey, Tamara Briner, Yaakov Stern,

Unawareness of memory loss is a challenging characteristic of Alzheimer's disease (AD) and other age-related neurodegenerative conditions at their earliest stages, adversely affecting important outcomes such as patient decision making and safety. The basis of this metacognitive disturbance has been elusive; however it is almost certainly determined in part by ... Read more >>

Neuropsychologia (Neuropsychologia)
[2015, 75:163-169]

Cited: 27 times

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The Reference Ability Neural Network Study: motivation, design, and initial feasibility analyses.

Yaakov Stern, Christian Habeck, Jason Steffener, Daniel Barulli, Yunglin Gazes, Qolamreza Razlighi, Danielle Shaked, Timothy Salthouse,

We introduce and describe the Reference Ability Neural Network Study and provide initial feasibility data. Based on analyses of large test batteries administered to individuals ranging from young to old, four latent variables, or reference abilities (RAs) that capture the majority of the variance in age-related cognitive change have been ... Read more >>

Neuroimage (NeuroImage)
[2014, 103:139-151]

Cited: 20 times

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Is improved contrast sensitivity a natural consequence of visual training?

Aaron Levi, Danielle Shaked, Duje Tadin, Krystel R Huxlin,

Many studies have shown that training and testing conditions modulate specificity of visual learning to trained stimuli and tasks. In visually impaired populations, generalizability of visual learning to untrained stimuli/tasks is almost always reported, with contrast sensitivity (CS) featuring prominently among these collaterally-improved functions. To understand factors underlying this difference, ... Read more >>

J Vis (Journal of vision)
[2015, 15(10):4]

Cited: 1 time

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Making cognitive latent variables manifest: distinct neural networks for fluid reasoning and processing speed.

Christian Habeck, Jason Steffener, Daniel Barulli, Yunglin Gazes, Qolamreza Razlighi, Danielle Shaked, Timothy Salthouse, Yaakov Stern,

Cognitive psychologists posit several specific cognitive abilities that are measured with sets of cognitive tasks. Tasks that purportedly tap a specific underlying cognitive ability are strongly correlated with one another, whereas performances on tasks that tap different cognitive abilities are less strongly correlated. For these reasons, latent variables are often ... Read more >>

J Cogn Neurosci (Journal of cognitive neuroscience)
[2015, 27(6):1249-1258]

Cited: 4 times

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Cognitive correlates of metamemory in Alzheimer's disease.

Danielle Shaked, Meagan Farrell, Edward Huey, Janet Metcalfe, Sarah Cines, Jason Karlawish, Elizabeth Sullo, Stephanie Cosentino,

Metamemory, or knowledge of one's memory abilities, is often impaired in individuals with Alzheimer's disease (AD), although the basis of this metacognitive deficit has not been fully articulated. Behavioral and imaging studies have produced conflicting evidence regarding the extent to which specific cognitive domains (i.e., executive function; memory) and brain ... Read more >>

Neuropsychology (Neuropsychology)
[2014, 28(5):695-705]

Cited: 9 times

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