Full Text Journal Articles by
Author Daniel M Cohen

Advertisement

Find full text journal articles






Age-dependent Interactions Among Clinical Characteristics, Viral Loads and Disease Severity in Young Children With Respiratory Syncytial Virus Infection.

Helena Brenes-Chacon, Cristina Garcia-Mauriño, Melissa Moore-Clingenpeel, Sara Mertz, Fang Ye, Daniel M Cohen, Octavio Ramilo, Asuncion Mejias,

<h4>Background</h4>Age-dependent differences in clinical presentation and viral loads in infants and young children with respiratory syncytial virus (RSV) infection, and their correlation with disease severity are poorly defined.<h4>Methods</h4>Previously healthy children <2 years old with mild (outpatients) and severe (inpatients) RSV infection were enrolled and viral loads measured by polymerase chain ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(2):116-122]

Cited: 0 times

View full text PDF listing >>



Predicting Adverse Outcomes for Shiga Toxin-Producing E. coli Infections in Emergency Departments.

Chu Yang Lin, Jianling Xie, Stephen B Freedman, Ryan McKee, David Schnadower, Phillip I Tarr, Yaron Finkelstein, Neil M Desai, Roni D Lane, Kelly R Bergmann, Ron L Kaplan, Selena Hariharan, Andrea T Cruz, Daniel M Cohen, Andrew Dixon, Sriram Ramgopal, Elizabeth C Powell, Jennifer Kilgar, Kenneth A Michelson, Martin Bitzan, Kenneth Yen, Garth D Meckler, Amy C Plint, Fran Balamuth, Stuart Bradin, Serge Gouin, April J Kam, James Meltzer, Tracy E Hunley, Usha Avva, Robert Porter, Daniel M Fein, Jeffrey P Louie, Gillian A M Tarr, ,

<h4>Objective</h4>To assess the performance of a hemolytic uremic syndrome (HUS) severity score among children with Shiga toxin-producing Escherichia coli (STEC) infections and HUS by stratifying them according to their risk of adverse events. The score has not been previously evaluated in a North American acute care setting.<h4>Study design</h4>We reviewed medical ... Read more >>

J Pediatr (The Journal of pediatrics)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Assessment of Alternative Personal Protective Equipment by Emergency Department Personnel During the SARS-CoV-2 Pandemic: A Simulation-Based Pilot Study.

Danielle Shavit, Oren Feldman, Khetam Hussein, Michal Meir, Asaf Miller, Amichai Gutgold, Ravit Idelman, Noa Kvatinsky, Daniel M Cohen, Itai Shavit,

<h4>Statement</h4>Shortage of personal protective equipment (PPE) for frontline healthcare workers managing the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is a major, global challenge. In this pilot study, we describe a simulation-based method for evaluating the suitability and acceptability of an alternative biological isolation garment (BIG, a gown ... Read more >>

Simul Healthc (Simulation in healthcare : journal of the Society for Simulation in Healthcare)
[2020, 15(6):445-446]

Cited: 0 times

View full text PDF listing >>



Using quality improvement to implement the CNS/AAN quality measure on rescue medication for seizures.

Anup D Patel, James Herbst, Annika Gibson, Mary Karn, Debbie Terry, Andrea Debs, Shannon Yarosz, William Parker, Daniel M Cohen,

<h4>Objective</h4>A multidisciplinary quality improvement (QI) team was established to conduct analysis of data for prescribed seizure rescue medication doses from January 2013 to December 2015 to identify and improve inappropriately low dose prescriptions. The QI team identified areas of focus for improvement opportunities and developed the project objective based on ... Read more >>

Epilepsia (Epilepsia)
[2020, 61(12):2712-2719]

Cited: 0 times

View full text PDF listing >>



1465. Age-Dependent Interactions Among Clinical Characteristics, Viral Loads and Disease Severity in Young Children with Respiratory Syncytial Virus Infection (RSV) Infection

Helena Brenes-Chacon, Cristina Garcia-Maurino, Melissa Moore-Clingenpeel, Sara Mertz, Fang Ye, Daniel M Cohen, Octavio Ramilo, Asuncion Mejias,

Abstract <h4>Background</h4> Differences in clinical presentation and viral loads according to age in young children with RSV, and their correlation with disease severity are poorly defined. The aim of this study was to define age-dependent the differences in demographic, clinical factors and viral loads between children < 2 years of ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(Suppl 1):S734-S735]

Cited: 0 times

View full text PDF listing >>



A Multiyear Cross-sectional Study of Guideline Adherence for the Timeliness of Opioid Administration in Children With Sickle Cell Pain Crisis.

David C Brousseau, Elizabeth R Alpern, James M Chamberlain, Angela M Ellison, Lalit Bajaj, Daniel M Cohen, Selena Hariharan, Lawrence J Cook, Monica Harding, Julie Panepinto, ,

<h4>Study objective</h4>The National Heart, Lung, and Blood Institute evidence-based guidelines for timeliness of opioid administration for sickle cell disease (SCD) pain crises recommend an initial opioid within 1 hour of arrival, with subsequent dosing every 30 minutes until pain is controlled. No multisite studies have evaluated guideline adherence, to our ... Read more >>

Ann Emerg Med (Annals of emergency medicine)
[2020, 76(3S):S6-S11]

Cited: 0 times

View full text PDF listing >>



Considerations for Designing EHR-Embedded Clinical Decision Support Systems for Antimicrobial Stewardship in Pediatric Emergency Departments.

Mustafa Ozkaynak, Noel Metcalf, Daniel M Cohen, Larissa S May, Peter S Dayan, Rakesh D Mistry,

<h4>Objective</h4>This study was aimed to explore the intersection between organizational environment, workflow, and technology in pediatric emergency departments (EDs) and how these factors impact antibiotic prescribing decisions.<h4>Methods</h4>Semistructured interviews with 17 providers (1 fellow and 16 attending faculty), and observations of 21 providers (1 physician assistant, 5 residents, 3 fellows, and ... Read more >>

Appl Clin Inform (Applied clinical informatics)
[2020, 11(4):589-597]

Cited: 0 times

View full text PDF listing >>



Radiographic Pneumonia in Febrile Infants 60 Days and Younger.

Todd A Florin, Octavio Ramilo, John D Hoyle, David M Jaffe, Leah Tzimenatos, Shireen M Atabaki, Daniel M Cohen, John M VanBuren, Prashant Mahajan, Nathan Kuppermann, ,

<h4>Objective</h4>Few prospective studies have assessed the occurrence of radiographic pneumonia in young febrile infants. We analyzed factors associated with radiographic pneumonias in febrile infants 60 days or younger evaluated in pediatric emergency departments.<h4>Study design</h4>We conducted a planned secondary analysis of a prospective cohort study within 26 emergency departments in a ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2020, :]

Cited: 0 times

View full text PDF listing >>



IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies.

Christian Leborgne, Elena Barbon, Jeffrey M Alexander, Hayley Hanby, Sandrine Delignat, Daniel M Cohen, Fanny Collaud, Saghana Muraleetharan, Dan Lupo, Joseph Silverberg, Karen Huang, Laetitia van Wittengerghe, Béatrice Marolleau, Adeline Miranda, Anna Fabiano, Victoria Daventure, Heena Beck, Xavier M Anguela, Giuseppe Ronzitti, Sean M Armour, Sebastien Lacroix-Desmazes, Federico Mingozzi,

Neutralizing antibodies to adeno-associated virus (AAV) vectors are highly prevalent in humans1,2, and block liver transduction3-5 and vector readministration6; thus, they represent a major limitation to in vivo gene therapy. Strategies aimed at overcoming anti-AAV antibodies are being studied7, which often involve immunosuppression and are not efficient in removing pre-existing ... Read more >>

Nat Med (Nature medicine)
[2020, 26(7):1096-1101]

Cited: 2 times

View full text PDF listing >>



Corticosteroids to prevent kidney scarring in children with a febrile urinary tract infection: a randomized trial.

Nader Shaikh, Timothy R Shope, Alejandro Hoberman, Gysella B Muniz, Sonika Bhatnagar, Andrew Nowalk, Robert W Hickey, Marian G Michaels, Diana Kearney, Howard E Rockette, Martin Charron, Ruth Lim, Massoud Majd, Eglal Shalaby-Rana, Marcia Kurs-Lasky, Daniel M Cohen, Ellen R Wald, Greg Lockhart, Hans G Pohl, Judith M Martin,

<h4>Background</h4>To evaluate the efficacy of adjuvant systemic corticosteroids in reducing kidney scarring. A previous study suggested that use of adjuvant systemic corticosteroids reduces kidney scarring in children radiologically confirmed to have extensive pyelonephritis. Efficacy of corticosteroids for children with febrile urinary tract infection (UTI) has not been studied.<h4>Methods</h4>Children aged 2 months ... Read more >>

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2020, 35(11):2113-2120]

Cited: 0 times

View full text PDF listing >>



Post-Acute Cortical Thickness in Children with Mild Traumatic Brain Injury versus Orthopedic Injury.

Ashley L Ware, Naomi J Goodrich-Hunsaker, Catherine Lebel, Ayushi Shukla, Elisabeth A Wilde, Tracy J Abildskov, Erin D Bigler, Daniel M Cohen, Leslie K Mihalov, Ann Bacevice, Barbara A Bangert, H Gerry Taylor, Keith Owen Yeates,

Studies of brain morphometry may illuminate the effects of pediatric mild traumatic brain injury (TBI; e.g., concussion). However, no published studies have examined cortical thickness in the early injury phases of pediatric mild TBI using an appropriate comparison group. The current study used an automated approach (i.e., FreeSurfer) to determine ... Read more >>

J Neurotrauma (Journal of neurotrauma)
[2020, 37(17):1892-1901]

Cited: 0 times

View full text PDF listing >>



National Imaging Trends of Recurrent Pediatric Urolithiasis.

Lindsey Barrick, Daniel M Cohen, Megan S Schober, Andrew Schwaderer,

OBJECTIVES:The aim of this study was to examine computed tomography (CT) and ultrasound (US) utilization trends in incident and prevalent pediatric emergency department (ED) urolithiasis patients before and after imaging guideline release. METHODS:We reviewed imaging modalities for children with 2 or more ED encounters between January 1, 2006, and September ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2020, 36(4):e217-e221]

Cited: 1 time

View full text PDF listing >>



Clinical Impact of Warmed Intravenous Saline in Sickle Cell Patients With Vasoocclusive Episodes.

Renee P Quarrie, Michael J Stoner, Julie M Choueiki, Bema K Bonsu, Daniel M Cohen,

<h4>Objectives</h4>In children with sickle cell disease treated for vasoocclusive episodes (VOEs), it is unknown if the temperature of infused fluids impacts clinical outcomes. We compared infusions of warmed and nonwarmed saline for treatment of VOE. We also assessed the tolerability and feasibility of infusing warmed saline in patients with VOEs.<h4>Methods</h4>Patients ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2020, 36(5):229-235]

Cited: 0 times

View full text PDF listing >>



Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.

James M Chamberlain, Jaideep Kapur, Shlomo Shinnar, Jordan Elm, Maija Holsti, Lynn Babcock, Alex Rogers, William Barsan, James Cloyd, Daniel Lowenstein, Thomas P Bleck, Robin Conwit, Caitlyn Meinzer, Hannah Cock, Nathan B Fountain, Ellen Underwood, Jason T Connor, Robert Silbergleit, , ,

<h4>Background</h4>Benzodiazepine-refractory, or established, status epilepticus is thought to be of similar pathophysiology in children and adults, but differences in underlying aetiology and pharmacodynamics might differentially affect response to therapy. In the Established Status Epilepticus Treatment Trial (ESETT) we compared the efficacy and safety of levetiracetam, fosphenytoin, and valproate in established ... Read more >>

Lancet (Lancet (London, England))
[2020, 395(10231):1217-1224]

Cited: 1 time

View full text PDF listing >>



Immune profiles provide insights into respiratory syncytial virus disease severity in young children.

Santtu Heinonen, Victoria M Velazquez, Fang Ye, Sara Mertz, Santiago Acero-Bedoya, Bennett Smith, Eleonora Bunsow, Cristina Garcia-Mauriño, Silvia Oliva, Daniel M Cohen, Melissa Moore-Clingenpeel, Mark E Peeples, Octavio Ramilo, Asuncion Mejias,

Respiratory syncytial virus (RSV) is associated with major morbidity in infants, although most cases result in mild disease. The pathogenesis of the disease is incompletely understood, especially the determining factors of disease severity. A better characterization of these factors may help with development of RSV vaccines and antivirals. Hence, identification ... Read more >>

Sci Transl Med (Science translational medicine)
[2020, 12(540):]

Cited: 5 times

View full text PDF listing >>



Predicting Hemolytic Uremic Syndrome and Renal Replacement Therapy in Shiga Toxin-producing Escherichia coli-infected Children.

Ryan S McKee, David Schnadower, Phillip I Tarr, Jianling Xie, Yaron Finkelstein, Neil Desai, Roni D Lane, Kelly R Bergmann, Ron L Kaplan, Selena Hariharan, Andrea T Cruz, Daniel M Cohen, Andrew Dixon, Sriram Ramgopal, Annie Rominger, Elizabeth C Powell, Jennifer Kilgar, Kenneth A Michelson, Darcy Beer, Martin Bitzan, Christopher M Pruitt, Kenneth Yen, Garth D Meckler, Amy C Plint, Stuart Bradin, Thomas J Abramo, Serge Gouin, April J Kam, Abigail Schuh, Fran Balamuth, Tracy E Hunley, John T Kanegaye, Nicholas E Jones, Usha Avva, Robert Porter, Daniel M Fein, Jeffrey P Louie, Stephen B Freedman, ,

<h4>Background</h4>Shiga toxin-producing Escherichia coli (STEC) infections are leading causes of pediatric acute renal failure. Identifying hemolytic uremic syndrome (HUS) risk factors is needed to guide care.<h4>Methods</h4>We conducted a multicenter, historical cohort study to identify features associated with development of HUS (primary outcome) and need for renal replacement therapy (RRT) (secondary ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(8):1643-1651]

Cited: 1 time

View full text PDF listing >>



A Paucity of Code Status Documentation Despite Increasing Complex Chronic Disease in Pediatrics.

Katherine A Battisti, Daniel M Cohen, Tran Bourgeois, David Kline, Songzhu Zhao, Maya S Iyer,

<b><i>Objectives:</i></b> An increasing number of children are living with complex chronic diseases (CCDs) due to medical advances. Despite a need for code status discussions (CSDs), there is great variability in the frequency and documentation of such conversations. The objective was to identify gaps in the documentation of CSDs within the ... Read more >>

J Palliat Med (Journal of palliative medicine)
[2020, 23(11):1452-1459]

Cited: 0 times

View full text PDF listing >>



Post-acute white matter microstructure predicts post-acute and chronic post-concussive symptom severity following mild traumatic brain injury in children.

Ashley L Ware, Ayushi Shukla, Naomi J Goodrich-Hunsaker, Catherine Lebel, Elisabeth A Wilde, Tracy J Abildskov, Erin D Bigler, Daniel M Cohen, Leslie K Mihalov, Ann Bacevice, Barbara A Bangert, H Gerry Taylor, Keith O Yeates,

<h4>Introduction</h4>Mild traumatic brain injury (TBI) is a global public health concern that affects millions of children annually. Mild TBI tends to result in subtle and diffuse alterations in brain tissue, which challenges accurate clinical detection and prognostication. Diffusion tensor imaging (DTI) holds promise as a diagnostic and prognostic tool, but ... Read more >>

Neuroimage Clin (NeuroImage. Clinical)
[2020, 25:102106]

Cited: 0 times

View full text PDF listing >>



Effect of a Motivational Interviewing-Based Intervention on Initiation of Mental Health Treatment and Mental Health After an Emergency Department Visit Among Suicidal Adolescents: A Randomized Clinical Trial.

Jacqueline Grupp-Phelan, Jack Stevens, Stephanie Boyd, Daniel M Cohen, Robert T Ammerman, Stacey Liddy-Hicks, Kendra Heck, Steven C Marcus, Lara Stone, John V Campo, Jeffrey A Bridge,

<h4>Importance</h4>Emergency department (ED) visits present opportunities to identify and refer suicidal youth for outpatient mental health care, although this practice is not routine.<h4>Objective</h4>To examine whether a motivational interviewing-based intervention increases linkage of adolescents to outpatient mental health services and reduces depression symptoms and suicidal ideation in adolescents seeking emergency care ... Read more >>

JAMA Netw Open (JAMA network open)
[2019, 2(12):e1917941]

Cited: 1 time

View full text PDF listing >>



What is the effect of a decision aid in potentially vulnerable parents? Insights from the head CT choice randomized trial.

Rachel M Skains, Nathan Kuppermann, James L Homme, Anupam B Kharbanda, Leah Tzimenatos, Jeffrey P Louie, Daniel M Cohen, Lise E Nigrovic, Jessica J Westphal, Nilay D Shah, Jonathan Inselman, Michael J Ferrara, Jeph Herrin, Victor M Montori, Erik P Hess,

<h4>Objective</h4>To test the hypotheses that use of the Head CT Choice decision aid would be similarly effective in all parent/patient dyads but parents with high (vs low) numeracy experience a greater increase in knowledge while those with low (vs high) health literacy experience a greater increase in trust.<h4>Methods</h4>This was a ... Read more >>

Health Expect (Health expectations : an international journal of public participation in health care and health policy)
[2020, 23(1):63-74]

Cited: 0 times

View full text PDF listing >>



Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus.

Jaideep Kapur, Jordan Elm, James M Chamberlain, William Barsan, James Cloyd, Daniel Lowenstein, Shlomo Shinnar, Robin Conwit, Caitlyn Meinzer, Hannah Cock, Nathan Fountain, Jason T Connor, Robert Silbergleit, ,

BACKGROUND:The choice of drugs for patients with status epilepticus that is refractory to treatment with benzodiazepines has not been thoroughly studied. METHODS:In a randomized, blinded, adaptive trial, we compared the efficacy and safety of three intravenous anticonvulsive agents - levetiracetam, fosphenytoin, and valproate - in children and adults with convulsive ... Read more >>

N Engl J Med (The New England journal of medicine)
[2019, 381(22):2103-2113]

Cited: 8 times

View full text PDF listing >>



Methodology and Demographics of a Brief Adolescent Alcohol Screen Validation Study.

Julie R Bromberg, Anthony Spirito, Thomas Chun, Michael J Mello, T Charles Casper, Fahd Ahmad, Lalit Bajaj, Kathleen M Brown, Lauren S Chernick, Daniel M Cohen, Joel Fein, Tim Horeczko, Michael N Levas, Brett McAninch, Michael Monuteaux, Colette C Mull, Jackie Grupp-Phelan, Elizabeth C Powell, Alexander Rogers, Rohit P Shenoi, Brian Suffoletto, Cheryl Vance, James G Linakis, ,

OBJECTIVE:The aim of this study was to determine the psychometric properties of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) 2-question alcohol screen within 16 Pediatric Emergency Care Applied Research Network pediatric emergency departments. This article describes the study methodology, sample characteristics, and baseline outcomes of the NIAAA 2-question ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2019, 35(11):737-744]

Cited: 3 times

View full text PDF listing >>



2619. Clinical Characteristics and Etiology of Community-Acquired Pneumonia in Children: A Contemporary, Prospective, Multicenter Study in Ohio, 2015–2018.

Ki Wook Yun, Rebecca Wallihan, Ankita P Desai, Sherman J Alter, Lilliam Ambroggio, Daniel M Cohen, Osama El-Assal, Sarah Marzec, Todd A Florin, Todd A Florin, Meghan Keaton, Samir S Shah, Asuncion Mejias, Octavio Ramilo, Octavio Ramilo,

AbstractBackgroundWorldwide, pneumonia is the leading cause of death in children <5 years of age and the second most common reason for hospitalization in children in the United States and Europe. This study was designed to describe the clinical characteristics and etiology of community-acquired pneumonia (CAP) in children.MethodsWe conducted a prospective, ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S911-S912]

Cited: 0 times

View full text PDF listing >>



Radiologic common data elements rates in pediatric mild traumatic brain injury.

Andrew R Mayer, Daniel M Cohen, Christopher J Wertz, Andrew B Dodd, Jody Shoemaker, Charles Pluto, Nicholas A Zumberge, Grace Park, Barbara A Bangert, Cindy Lin, Nori M Minich, Ann M Bacevice, Erin D Bigler, Richard A Campbell, Faith M Hanlon, Timothy B Meier, Scott J Oglesbee, John P Phillips, Amy Pottenger, Nicholas A Shaff, H Gerry Taylor, Ronald A Yeo, Kristy B Arbogast, John J Leddy, Christina L Master, Rebekah Mannix, Roger L Zemek, Keith Owen Yeates,

OBJECTIVE:The nosology for classifying structural MRI findings following pediatric mild traumatic brain injury (pmTBI) remains actively debated. Radiologic common data elements (rCDE) were developed to standardize reporting in research settings. However, some rCDE are more specific to trauma (probable rCDE). Other more recently proposed rCDE have multiple etiologies (possible rCDE), ... Read more >>

Neurology (Neurology)
[2020, 94(3):e241-e253]

Cited: 0 times

View full text PDF listing >>



A Quality Initiative Reducing Adverse Outcomes in Pediatric Patients with DKA During Intrafacility Transit.

Michael J Stoner, Kelli S Burkey, Daniel M Cohen,

Introduction:Treatment of diabetic ketoacidosis (DKA) requires close and timely monitoring to prevent serious adverse events. This quality improvement project details how our institution improved blood glucose monitoring around hospital admission. The project aimed to increase the blood glucose assessments for children with DKA receiving insulin in the emergency department (ED) ... Read more >>

Pediatr Qual Saf (Pediatric quality & safety)
[2019, 4(4):e194]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1117 s