Full Text Journal Articles by
Author Daniel Leon

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Urine Biomarker Assessment of Infant Adherence to Isoniazid Prophylaxis.

Sylvia M LaCourse, Daniel Leon, Nuttada Panpradist, Barbra A Richardson, Elizabeth Maleche-Obimbo, Jerphason Mecha, Daniel Matemo, Jaclyn N Escudero, John Kinuthia, Barry Lutz, Grace John-Stewart,

We assessed adherence in an infant tuberculosis prevention trial in Kenya with a urine isoniazid metabolite-detecting dipstick. Ninety-seven infants had 155 assays performed; 77 (49.7%) were found to be positive despite caregiver-reported adherence. Positive assays were associated with maternal secondary education, HIV suppression and no reported missed doses in past ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):e43-e45]

Cited: 0 times

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Correction to: Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model.

Bruno Paun, Daniel García Leon, Alex Claveria Cabello, Roso Mares Pages, Elena de la Calle Vargas, Paola Contreras Muñoz, Vanessa Venegas Garcia, Joan Castell-Conesa, Mario Marotta Baleriola, Jose Raul Herance Camacho,

Eur Radiol Exp (European radiology experimental)
[2020, 4(1):69]

Cited: 0 times

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Pharmacogenetics of hypoglycemia associated with sulfonylurea therapy in usual clinical care.

Sabrina L Mitchell, Daniel A Carranza Leon, Sandip Chaugai, Vivian K Kawai, Rebecca T Levinson, Wei-Qi Wei, C Michael Stein,

Hypoglycemia is a common complication among type 2 diabetes mellitus (T2DM) patients receiving sulfonylurea therapy. The aim of this study was to determine if genetic contributions to sulfonylurea pharmacokinetics or pharmacodynamics substantially affect the risk of hypoglycemia in these patients. In a retrospective case-control study in European American patients with ... Read more >>

Pharmacogenomics J (The pharmacogenomics journal)
[2020, 20(6):831-839]

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Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model.

Bruno Paun, Daniel García Leon, Alex Claveria Cabello, Roso Mares Pages, Elena de la Calle Vargas, Paola Contreras Muñoz, Vanessa Venegas Garcia, Joan Castell-Conesa, Mario Marotta Baleriola, Jose Raul Herance Camacho,

<h4>Background</h4>Skeletal muscle injury characterisation during healing supports trauma prognosis. Given the potential interest of computed tomography (CT) in muscle diseases and lack of in vivo CT methodology to image skeletal muscle wound healing, we tracked skeletal muscle injury recovery using in vivo micro-CT in a rat model to obtain a ... Read more >>

Eur Radiol Exp (European radiology experimental)
[2020, 4(1):33]

Cited: 0 times

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Three-dimensional cardiac fibre disorganization as a novel parameter for ventricular arrhythmia stratification after myocardial infarction.

Daniel G León, Mariña López-Yunta, José Manuel Alfonso-Almazán, Manuel Marina-Breysse, Jorge G Quintanilla, Javier Sánchez-González, Carlos Galán-Arriola, Francisco Castro-Núñez, Juan José González-Ferrer, Borja Ibáñez, Julián Pérez-Villacastín, Nicasio Pérez-Castellano, Valentín Fuster, José Jalife, Mariano Vázquez, Jazmín Aguado-Sierra, David Filgueiras-Rama,

<h4>Aims</h4>Myocardial infarction (MI) alters cardiac fibre organization with unknown consequences on ventricular arrhythmia. We used diffusion tensor imaging (DTI) of three-dimensional (3D) cardiac fibres and scar reconstructions to identify the main parameters associated with ventricular arrhythmia inducibility and ventricular tachycardia (VT) features after MI.<h4>Methods and results</h4>Twelve pigs with established MI ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2019, 21(5):822-832]

Cited: 1 time

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The Power of Patient Norms: Postoperative Pathway Associated With Shorter Hospital Stay After Free Autologous Breast Reconstruction.

Danielle H Rochlin, Daniel Sotelo Leon, Caroline Yu, Chao Long, Rahim Nazerali, Gordon K Lee,

<h4>Introduction</h4>Enhanced recovery after surgery pathways designed to optimize postoperative care have become increasingly popular across multiple surgical specialties with proven benefits. In this retrospective cohort study, we present a comparative evaluation of the impact of protocol-based postoperative care on free autologous breast reconstruction patients.<h4>Methods</h4>With institutional review board approval, we performed ... Read more >>

Ann Plast Surg (Annals of plastic surgery)
[2019, 82(5S Suppl 4):S320-S324]

Cited: 0 times

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Upper Extremity Angiographic Patterns in Systemic Sclerosis: Implications for Surgical Treatment.

Jacinta Leyden, Matthew B Burn, Victor Wong, Daniel Sotelo Leon, Yukitoshi Kaizawa, Lorinda Chung, James Chang,

<h4>Purpose</h4>Conventional angiography is often used in the preoperative work-up of hand surgery patients with systemic sclerosis. The goal of this study was to propose a classification system based on the pattern of arterial involvement in a series of upper extremity angiograms. The authors hypothesized that this classification system would demonstrate ... Read more >>

J Hand Surg Am (The Journal of hand surgery)
[2019, 44(11):990.e1-990.e7]

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Implications of bipolar voltage mapping and magnetic resonance imaging resolution in biventricular scar characterization after myocardial infarction.

Mariña López-Yunta, Daniel G León, José Manuel Alfonso-Almazán, Manuel Marina-Breysse, Jorge G Quintanilla, Javier Sánchez-González, Carlos Galán-Arriola, Victoria Cañadas-Godoy, Daniel Enríquez-Vázquez, Carlos Torres, Borja Ibáñez, Julián Pérez-Villacastín, Nicasio Pérez-Castellano, José Jalife, Mariano Vázquez, Jazmín Aguado-Sierra, David Filgueiras-Rama,

<h4>Aims</h4>We aimed to study the differences in biventricular scar characterization using bipolar voltage mapping compared with state-of-the-art in vivo delayed gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) imaging and ex vivo T1 mapping.<h4>Methods and results</h4>Ten pigs with established myocardial infarction (MI) underwent in vivo scar characterization using LGE-CMR imaging and high-density voltage ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2019, 21(1):163-174]

Cited: 2 times

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Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection.

QiPing Feng, Wei-Qi Wei, Sandip Chaugai, Barbara G Carranza Leon, Jonathan D Mosley, Daniel A Carranza Leon, Lan Jiang, Andrea Ihegword, Christian M Shaffer, MacRae F Linton, Cecilia P Chung, C Michael Stein,

<h4>Importance</h4>Whether low levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased risk of sepsis and poorer outcomes is unknown.<h4>Objective</h4>To examine the association between LDL-C levels and risk of sepsis among patients admitted to the hospital with infection.<h4>Design, setting, and participants</h4>Cohort study in which deidentified electronic health records were used ... Read more >>

JAMA Netw Open (JAMA network open)
[2019, 2(1):e187223]

Cited: 3 times

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Urinary Tract Infection After Hysterectomy for Benign Gynecologic Conditions or Pelvic Reconstructive Surgery.

Sherif A El-Nashar, Ruchira Singh, Jennifer J Schmitt, Daniel Carranza Leon, Chetna Arora, John B Gebhart, John A Occhino,

<h4>Objective</h4>To report rates and identify risk factors for urinary tract infection (UTI) after hysterectomy for benign conditions or combined with pelvic reconstructive surgery.<h4>Methods</h4>This is a cohort study that included women who underwent hysterectomy either for benign gynecologic conditions or hysterectomy combined with pelvic reconstructive surgery from January 1, 2012, through ... Read more >>

Obstet Gynecol (Obstetrics and gynecology)
[2018, 132(6):1347-1357]

Cited: 0 times

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Threshold-Based Quantification in a Multiline Lateral Flow Assay via Computationally Designed Capture Efficiency.

David J Gasperino, Daniel Leon, Barry Lutz, David M Cate, Kevin P Nichols, David Bell, Bernhard H Weigl,

Lateral flow assays (LFAs) are widely used for yes/no detection of analytes, but they are not well-suited for quantification. We show that the sensitivity of the test line in a lateral flow assay can be tuned to appear at a specific sample concentration by varying the density of capture molecules ... Read more >>

Anal Chem (Analytical chemistry)
[2018, 90(11):6643-6650]

Cited: 0 times

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Sorting out the phytoprostane and phytofuran profile in vegetable oils

Raúl Domínguez-Perles, Alexander Guy, Ángel Abellán, Ángel Gil-Izquierdo, Camille Oger, Daniel León, Federico Ferreres, Jean Marie Galano, Thierry Durand,

Phytoprostanes (PhytoPs) and phytofurans (PhytoFs) are prostaglandin-like compounds, contributing to defense signaling and prevention of cellular damage. These plant oxylipins result from autoxidation of α-linolenic acid (ALA) and have been proposed as new bioactive compounds due to their structural analogies with isoprostanes (IsoPs) and prostanoids derived from arachidonic acid in ... Read more >>

Food Res Int (Food research international (Ottawa, Ont.))
[2018, 107:619-628]

Cited: 1 time

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Using Mesh to Reinforce the Abdominal Wall in Abdominal Free Flaps for Breast Reconstruction: Is There a Benefit? What are the Risks?

Daniel Sotelo Leon, Rahim Nazerali, Gordon Kwanlyp Lee,

INTRODUCTION:Abdominal wall integrity may be compromised after abdominal flap harvest for breast reconstruction, leading to bulging or herniation due to weakening of the abdominal wall and dissection through the rectus muscle. Mesh can be used to reinforce the abdominal wall to reduce the risk of hernia formation postoperatively, especially in ... Read more >>

Ann Plast Surg (Annals of plastic surgery)
[2018, 80(5S Suppl 5):S295-S298]

Cited: 0 times

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Sorting out the phytoprostane and phytofuran profile in vegetable oils.

Raúl Domínguez-Perles, Ángel Abellán, Daniel León, Federico Ferreres, Alexander Guy, Camille Oger, Jean Marie Galano, Thierry Durand, Ángel Gil-Izquierdo,

Phytoprostanes (PhytoPs) and phytofurans (PhytoFs) are prostaglandin-like compounds, contributing to defense signaling and prevention of cellular damage. These plant oxylipins result from autoxidation of α-linolenic acid (ALA) and have been proposed as new bioactive compounds due to their structural analogies with isoprostanes (IsoPs) and prostanoids derived from arachidonic acid in ... Read more >>

Food Res Int (Food research international (Ottawa, Ont.))
[2018, 107:619-628]

Cited: 2 times

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Modulation of motor cortex excitability by paired peripheral and transcranial magnetic stimulation.

Hatice Kumru, Sergiu Albu, John Rothwell, Daniel Leon, Cecilia Flores, Eloy Opisso, Josep Maria Tormos, Josep Valls-Sole,

<h4>Objective</h4>Repetitive application of peripheral electrical stimuli paired with transcranial magnetic stimulation (rTMS) of M1 cortex at low frequency, known as paired associative stimulation (PAS), is an effective method to induce motor cortex plasticity in humans. Here we investigated the effects of repetitive peripheral magnetic stimulation (rPMS) combined with low frequency ... Read more >>

Clin Neurophysiol (Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology)
[2017, 128(10):2043-2047]

Cited: 6 times

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Determining Optimal Route of Hysterectomy for Benign Indications: Clinical Decision Tree Algorithm.

Jennifer J Schmitt, Daniel A Carranza Leon, John A Occhino, Amy L Weaver, Sean C Dowdy, Jamie N Bakkum-Gamez, Kalyan S Pasupathy, John B Gebhart,

<h4>Objective</h4>To evaluate practice change after initiation of a robotic surgery program using a clinical algorithm to determine the optimal surgical approach to benign hysterectomy.<h4>Methods</h4>A retrospective postrobot cohort of benign hysterectomies (2009-2013) was identified and the expected surgical route was determined from an algorithm using vaginal access and uterine size as ... Read more >>

Obstet Gynecol (Obstetrics and gynecology)
[2017, 129(1):130-138]

Cited: 4 times

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tDCS does not enhance the effects of robot-assisted gait training in patients with subacute stroke.

Daniel Leon, Mar Cortes, Jessica Elder, Hatice Kumru, Sara Laxe, Dylan James Edwards, Josep Maria Tormos, Montserrat Bernabeu, Alvaro Pascual-Leone,

<h4>Background</h4>Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique, which can modulate cortical excitability and combined with rehabilitation therapies may improve motor recovery after stroke.<h4>Objective</h4>Our aim was to study the feasibility of a 4-week robotic gait training protocol combined with tDCS, and to study tDCS to the leg ... Read more >>

Restor Neurol Neurosci (Restorative neurology and neuroscience)
[2017, 35(4):377-384]

Cited: 5 times

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Coca cultivation and crop eradication in Colombia: The challenges of integrating rural reality into effective anti-drug policy.

Alexander Rincón-Ruiz, Hyarold Leonardo Correa, Daniel Oswaldo León, Stewart Williams,

This paper examines the positive and negative (or intended and unintended) impacts of anti-drug policies such as the aerial spraying of coca crops in Colombia. It provides spatial analysis of coca cultivation and crop eradication at a fine scale of resolution using the latest UNODC data. The findings suggest that ... Read more >>

Int J Drug Policy (The International journal on drug policy)
[2016, 33:56-65]

Cited: 1 time

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The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling.

Laurence Booth, Jane L Roberts, Mehrad Tavallai, Timothy Webb, Daniel Leon, Jesse Chen, William P McGuire, Andrew Poklepovic, Paul Dent,

We generated afatinib resistant clones of H1975 lung cancer cells by transient exposure of established tumors to the drug and collected the re-grown tumors. Afatinib resistant H1975 clones did not exhibit any additional mutations in proto-oncogenes when compared to control clones. Afatinib resistant H1975 tumor clones expressed less PTEN than ... Read more >>

Oncotarget (Oncotarget)
[2016, 7(15):19620-19630]

Cited: 27 times

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[Description of functional outcome in pediatric traumatic brain injury after a comprehensive rehabilitation programme].

Sara Laxe, Daniel León, Dalila Salgado, Mikel Zabaleta,

<h4>Introduction</h4>Traumatic brain injury is the leading cause of mortality and disability in children in the developed countries. Despite the plasticity of an infant's brain, injury at this early stage can lead to important sequelae that will affect functioning later in life. The understanding of the functional profile after a traumatic ... Read more >>

Neurocirugia (Astur) (Neurocirugia (Asturias, Spain))
[2015, 26(2):84-89]

Cited: 1 time

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How does dysautonomia influence the outcome of traumatic brain injured patients admitted in a neurorehabilitation unit?

Sara Laxe, Rosa Terré, Daniel León, Montserrat Bernabeu,

<h4>Background</h4>Patients surviving severe traumatic brain injury (TBI) may suffer from symptoms presumed to be related to an excessive sympathetic production known as paroxysmal sympathetic hyperactivity (PSH). While this condition is more common in the acute phase, prognosis is less clear in rehabilitation settings.<h4>Aim</h4>The goal of this study is to describe ... Read more >>

Brain Inj (Brain injury)
[2013, 27(12):1383-1387]

Cited: 5 times

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An observational report of intensive robotic and manual gait training in sub-acute stroke.

Lucas Conesa, Úrsula Costa, Eva Morales, Dylan J Edwards, Mar Cortes, Daniel León, Montserrat Bernabeu, Josep Medina,

<h4>Background</h4>The use of automated electromechanical devices for gait training in neurological patients is increasing, yet the functional outcomes of well-defined training programs using these devices and the characteristics of patients that would most benefit are seldom reported in the literature. In an observational study of functional outcomes, we aimed to ... Read more >>

J Neuroeng Rehabil (Journal of neuroengineering and rehabilitation)
[2012, 9:13]

Cited: 12 times

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[Changes in the functional magnetic resonance imaging of the sensorimotor cortex in traumatic brain injury after intensive rehabilitation].

Fernanda P S Lima, Mário O Lima, Daniel León, Carles Falcon, Jose Carlos Cogo, Paulo R G Lucareli, Núria Bargalló, Joan Vidal, Montserrat Bernabeu-Guitart, Natacha León-Álvarez, Juliane G A Lucareli, Carmen Junqué,

<h4>Aim</h4>To evaluate the potential reorganization of the sensorimotor cortex in a patient with traumatic brain injury after an intensive motor rehabilitation.<h4>Patients and methods</h4>A 17-year-old male with severe traumatic brain injury was submitted to functional magnetic resonance imaging (fMRI) analyses of motor control before and after motor rehabilitation. The motor tasks ... Read more >>

Rev Neurol (Revista de neurologia)
[2010, 51(7):403-411]

Cited: 0 times

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