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Author Danfeng Zhang

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Decreased bone marrow regulatory innate lymphoid cells show a distinctive miRNA profiling in aplastic anemia.

Yingmei Li, Dingming Wan, Rong Guo, Fang Wang, Lijie Han, Danfeng Zhang, Haizhou Xing, Weijie Cao, Yu Liu, Xinsheng Xie, Jifeng Yu, Zhongxing Jiang,

<h4>Objectives</h4>A new regulatory subpopulation of innate lymphoid cells (ILCs), regulatory innate lymphoid cells (ILCregs), has been identified with both innate lymphoid cells and regulatory cells characteristics. The purpose of this study is to explore ILCregs and its associated miRNAs in patients with aplastic anemia (AA) by evaluating ILCregs frequency, associated ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):37-42]

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An alpha/beta chimeric peptide molecular brush for eradicating MRSA biofilms and persister cells to mitigate antimicrobial resistance.

Ximian Xiao, Si Zhang, Sheng Chen, Yuxin Qian, Jiayang Xie, Zihao Cong, Danfeng Zhang, Jingcheng Zou, Wenjing Zhang, Zhemin Ji, Ruxin Cui, Zhongqian Qiao, Weinan Jiang, Yidong Dai, Yun Wang, Xiaoyan Shao, Yun Sun, Jiang Xia, Jian Fei, Runhui Liu,

Infections involving methicillin-resistant Staphylococcus aureus present great challenges, especially when biofilms and persister cells are involved. In this work, an α/β chimeric polypeptide molecular brush (α/β CPMB) is reported to show excellent performance in inhibiting the formation of biofilms and eradicating established biofilms. Additionally, the polymer brush efficiently killed metabolically ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(24):6883-6889]

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Roles of tolC on tolerance to bile salts and biofilm formation in Cronobacter malonaticus.

Xin Wang, Yaping Wang, Na Ling, Yizhong Shen, Danfeng Zhang, Dengyu Liu, Dexin Ou, Qingping Wu, Yingwang Ye,

Bile salts is one of essential components of bile secreted into the intestine to confer antibacterial protection. Cronobacter species are associated with necrotizing enterocolitis in newborns and show a strong tolerance to bile salts. However, little attempt has been made to focus on the molecular basis of the tolerance to ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, :]

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Chlorogenic acid induces ROS-dependent apoptosis in Fusarium fujikuroi and decreases the postharvest rot of cherry tomato

Kai Kai, Rui Wang, Wanling Bi, Zhitao Ma, Wei Shi, Yingwang Ye, Danfeng Zhang,

Chlorogenic acid is a plant polyphenol with antioxidant and antimicrobial activities. Fusarium fujikuroi is a fungal pathogen that causes many vegetables and fruits, including tomato, to rot. The effects of chlorogenic acid on the development of Fusarium rot of cherry tomato fruit were examined in the present study. Results showed ... Read more >>

World J Microbiol Biotechnol (World journal of microbiology & biotechnology)
[2021, 37(6):93]

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NETs Lead to Sympathetic Hyperactivity After Traumatic Brain Injury Through the LL37-Hippo/MST1 Pathway.

Kaixin Zhu, Yibai Zhu, Xiaoxiang Hou, Wen Chen, Xiaolin Qu, Yelei Zhang, Zhenxing Li, Chunhui Wang, Jigang Chen, Liquan Lv, Junyu Wang, Danfeng Zhang, Lijun Hou,

<b>Background:</b> Paroxysmal sympathetic hyperactivity (PSH) is one of the important reasons for the high mortality and morbidity of traumatic brain injury (TBI). We aim to explore the role of the neutrophil extracellular traps (NETs) in the pathogenesis of sympathetic hyperexcitability after TBI and the underlying mechanisms, providing evidence for clinical ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:621477]

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BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.

Danfeng Zhang, Jingcao Huang, Fangfang Wang, Hong Ding, Yushan Cui, Yan Yang, Juan Xu, Hongmei Luo, Yuhan Gao, Ling Pan, Yu Wu, Yuping Gong, Liping Xie, Zhigang Liu, Ying Qu, Li Zhang, Weiping Liu, Wenyan Zhang, Sha Zhao, Qing Yi, Ting Niu, Yuhuan Zheng,

Multiple myeloma (MM) is an aggressive malignancy characterized by terminally differentiated plasma cells accumulation in the bone marrow (BM). MM BM exhibits elevated MΦs (macrophages) numbers relative to healthy BM. Current evidence indicates that MM-MΦs (MM-associated macrophages) have pro-myeloma functions, and BM MM-MΦs numbers negatively correlate with patient survival. Here, ... Read more >>

Cell Death Dis (Cell death & disease)
[2021, 12(5):495]

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Recombinant Expression of Trametes versicolor Aflatoxin B1-Degrading Enzyme (TV-AFB1D) in Engineering Pichia pastoris GS115 and Application in AFB1 Degradation in AFB1-Contaminated Peanuts.

Peizhou Yang, Wei Xiao, Shuhua Lu, Suwei Jiang, Zhi Zheng, Danfeng Zhang, Min Zhang, Shaotong Jiang, Shuying Jiang,

Aflatoxins seriously threaten the health of humans and animals due to their potential carcinogenic properties. Enzymatic degradation approach is an effective and environmentally friendly alternative that involves changing the structure of aflatoxins. In this study, <i>Trametes versicolor</i> aflatoxin B<sub>1</sub>-degrading enzyme gene (TV-AFB<sub>1</sub>D) was integrated into the genome of <i>Pichia pastoris</i> ... Read more >>

Toxins (Basel) (Toxins)
[2021, 13(5):]

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Chlorogenic acid induces ROS-dependent apoptosis in Fusarium fujikuroi and decreases the postharvest rot of cherry tomato.

Kai Kai, Rui Wang, Wanling Bi, Zhitao Ma, Wei Shi, Yingwang Ye, Danfeng Zhang,

Chlorogenic acid is a plant polyphenol with antioxidant and antimicrobial activities. Fusarium fujikuroi is a fungal pathogen that causes many vegetables and fruits, including tomato, to rot. The effects of chlorogenic acid on the development of Fusarium rot of cherry tomato fruit were examined in the present study. Results showed ... Read more >>

World J Microbiol Biotechnol (World journal of microbiology & biotechnology)
[2021, 37(6):93]

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Pantoea vagans strain BWL1 controls blue mold in mandarin fruit by inhibiting ergosterol biosynthesis in Penicillium expansum

Wanling Bi, Rui Wang, Youyang Yang, Yu Wang, Zhitao Ma, Qi Wang, Danfeng Zhang,

Penicillium expansum is a major postharvest fungal pathogen of a variety of fruits. Recently, Pen. expansum has been reported to infect citrus fruit; however, the management of Pen. expansum on citrus has not been studied. Pantoea vagans strain BWL1 was isolated from the surface of mandarin fruit. Here, its inhibitory ... Read more >>

Biol Control (Biological control.)
[2021, :Not Available]

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Oxidative Phosphorylation-Mediated E-Selectin Upregulation Is Associated With Endothelia-Monocyte Adhesion in Human Coronary Artery Endothelial Cells Treated With Sera From Patients With Kawasaki Disease.

Danfeng Zhang, Lingjuan Liu, Yuxing Yuan, Tiewei Lv, Xupei Huang, Jie Tian,

<b>Background and aims:</b> E-selectin is a cell adhesion molecule of the vascular endothelium that mediates leukocyte rolling in the early inflammatory responses in many diseases including Kawasaki disease (KD). Previous studies have demonstrated that the expression levels of E-selectin was significantly increased in the sera of KD patients and in ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2021, 9:618267]

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The Alteration of M6A-Tagged Transcript Profiles in the Retina of Rats After Traumatic Optic Neuropathy.

Xiaolin Qu, Kaixin Zhu, Zhenxing Li, Danfeng Zhang, Lijun Hou,

Messager RNA (mRNA) can be modified in a variety of ways, among which the modification of N6-methyladenosine (m6A) is one of the most common ones. Recent studies have found that the m6A modification in mRNA could functionally regulate the splicing, localization, translation, and stability of mRNA, which might be closely ... Read more >>

Front Genet (Frontiers in genetics)
[2021, 12:628841]

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Hemodynamics is associated with vessel wall remodeling in patients with middle cerebral artery stenosis.

Danfeng Zhang, Xinying Wu, Jie Tang, Peng Wang, Guo Zhong Chen, Xindao Yin,

<h4>Objectives</h4>To evaluate the relationship between hemodynamics and vessel wall remodeling patterns in middle cerebral artery (MCA) stenosis based on high-resolution magnetic resonance imaging and computational fluid dynamics (CFD).<h4>Methods</h4>Forty consecutive patients with recent ischemic stroke or transient ischemic attack attributed to unilateral atherosclerotic MCA stenosis (50-99%) were prospectively recruited. All patients ... Read more >>

Eur Radiol (European radiology)
[2021, 31(7):5234-5242]

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Role of fliC on biofilm formation, adhesion, and cell motility in Cronobacter malonaticus and regulation of luxS.

Na Ling, Xin Wang, Dengyu Liu, Yizhong Shen, Danfeng Zhang, Dexin Ou, Hongying Fan, Juan Wang, Yu Ding, Jumei Zhang, Qingping Wu, Yingwang Ye,

Cronobacter malonaticus is one of the important foodborne pathogens causing infections mainly in adults. Biofilm formation, adhesion, and motility in Cronobacter have been documented, but the implying molecular mechanism has received little attention. Here, a comparison in biofilm formation, adhesion ability, and cell motility among wild type (WT), △luxS, and ... Read more >>

Food Chem Toxicol (Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association)
[2021, 149:111940]

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Cytotoxic and anti-tumor effects of 3,4-seco-lupane triterpenoids from the leaves of Eleutherococcus sessiliflorus against hepatocellular carcinoma.

Haohao Wang, Wenliu Yu, Danfeng Zhang, Yan Zhao, Chen Chen, Hongyan Zhu, Enbo Cai, Zhaowei Yan,

A rich of 3,4-<i>seco</i>-lupane triterpenoids (3,4-SLT), including chiisanoside (CSS), divaroside (DVS), sessiloside-A1 (SSA), chiisanogenin (CSG), sessiligenin (SSG), were isolated from the ethanol extract of the leaves of <i>Eleutherococcus sessiliflorus</i> (LES). The present study was performed to explore the cytotoxic and anti-tumor effects of the isolated five ones, as well as ... Read more >>

Nat Prod Res (Natural product research)
[2020, :1-5]

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Identification of a Novel Six-Long Noncoding RNA Signature for Molecular Diagnosis of Dilated Cardiomyopathy.

Hui Zhang, Xiajing Chen, Danfeng Zhang, Lingjuan Liu, Jing Song, Yinyin Xu, Jie Tian,

Long noncoding RNAs (lncRNAs) may serve as potential molecular diagnostic markers to improve the capacity of earlier and more accurate diagnosis of dilated cardiomyopathy (DCM). We integrated five independent transcriptomic datasets (<i>n</i> = 504) from Gene Expression Omnibus for systematic identification of lncRNA-based diagnostic biomarkers in DCM. The multivariate logistic regression model ... Read more >>

DNA Cell Biol (DNA and cell biology)
[2020, :]

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Improving the yield of Anoectochilus roxburghii by Bacillus licheniformis cultured in Agaricus bisporus industrial wastewater

Jiafu Huang, Axian Huang, Luanmei Lu, Weikang Jiang, Danfeng Zhang, Qici Wu, Peng Li, Xiuyan Zhong,

There is a large amount of industrial wastewater produced by the mushroom industry during the canning processing each year, which could provide abundant carbon, nitrogen and inorganic salts for microbial growth. The aim of this study was to optimize the culture conditions for Bacillus licheniformis cultured in the Agaricus bisporus ... Read more >>

Electron J Biotechnol (Electronic Journal of Biotechnology.)
[2020, 48:13-22]

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Normal Structure and Function of Endothecium Chloroplasts Maintained by ZmMs33-Mediated Lipid Biosynthesis in Tapetal Cells Are Critical for Anther Development in Maize.

Taotao Zhu, Ziwen Li, Xueli An, Yan Long, Xiaofeng Xue, Ke Xie, Biao Ma, Danfeng Zhang, Yijian Guan, Canfang Niu, Zhenying Dong, Quancan Hou, Lina Zhao, Suowei Wu, Jinping Li, Weiwei Jin, Xiangyuan Wan,

Genic male sterility (GMS) is critical for heterosis utilization and hybrid seed production. Although GMS mutants and genes have been studied extensively in plants, it has remained unclear whether chloroplast-associated photosynthetic and metabolic activities are involved in the regulation of anther development. In this study, we characterized the function of ... Read more >>

Mol Plant (Molecular plant)
[2020, 13(11):1624-1643]

Cited: 2 times

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Effect of chlorogenic acid on controlling kiwifruit postharvest decay caused by Diaporthe sp.

Danfeng Zhang, Wanling Bi, Kai Kai, Yingwang Ye, Jia Liu,

Chlorogenic acid (CGA) is a phenolic compound derived from plants that has anti-microbial activity. Effect of CGA toward Diaporthe sp. infection in kiwifruit was evaluated in the present study. Results demonstrated that fungal spore germination, germ tube elongation, and mycelial growth were all significantly inhibited by CGA. Exposure of Diaporthe ... Read more >>

Lebensm Wiss Technol (Lebensmittel-Wissenschaft + [i.e. und] Technologie.)
[2020, 132:Not Available]

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Prevalence and population analysis of Vibrio parahaemolyticus in retail aquatic products from the southern Fujian coast, China

Yuanqing Hu, Fengxia Li, Ying Zheng, Zhichao Zeng, Guoguang Zhang, Danfeng Zhang, Xinan Jiao, Liqing Guo,

Vibrio parahaemolyticus is one of the most hazardous pathogens causing seafood‐borne diseases in the southern Fujian coast, China. From June to October 2016, a total of 250 samples were collected from retail markets in the Xiamen, Quanzhou, and Zhangzhou regions. Seventy‐seven V. parahaemolyticus isolates were identified using polymerase chain reaction ... Read more >>

(Journal of food safety.)
[2020, 40(5):Not Available]

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Molecular regulation of ZmMs7 required for maize male fertility and development of a dominant male-sterility system in multiple species.

Xueli An, Biao Ma, Meijuan Duan, Zhenying Dong, Ruogu Liu, Dingyang Yuan, Quancan Hou, Suowei Wu, Danfeng Zhang, Dongcheng Liu, Dong Yu, Yuwen Zhang, Ke Xie, Taotao Zhu, Ziwen Li, Simiao Zhang, Youhui Tian, Chang Liu, Jinping Li, Longping Yuan, Xiangyuan Wan,

Understanding the molecular basis of male sterility and developing practical male-sterility systems are essential for heterosis utilization and commercial hybrid seed production in crops. Here, we report molecular regulation by genic male-sterility gene <i>maize male sterility 7</i> (<i>ZmMs7</i>) and its application for developing a dominant male-sterility system in multiple species. ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2020, 117(38):23499-23509]

Cited: 1 time

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A Novel Immune-Related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia.

Shujuan Wang, Lu Yang, Yajun Liu, Yan Xu, Danfeng Zhang, Zhongxing Jiang, Chong Wang, Yanfang Liu,

<h4>Background</h4>Acute myeloid leukemia (AML) is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow (BM) microenvironment. Infiltrated immune cells and stromal cells are an important part of the BM microenvironment and significantly affect the progression of AML. Recently, the competing endogenous RNA hypothesis ... Read more >>

Front Oncol (Frontiers in oncology)
[2020, 10:1579]

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Insights Into Coronary Artery Lesions in Kawasaki Disease.

Danfeng Zhang, Lingjuan Liu, Xupei Huang, Jie Tian,

This review summarizes recent advances in understanding the development of coronary arteritis in Kawasaki disease. Kawasaki disease is the most common cause of acquired heart disease among children characterized with coronary artery abnormalities, which can cause myocardial ischemia, infarction, and even death. The pathogenic factors of Kawasaki disease and the ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:493]

Cited: 1 time

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Alterations in effective connectivity within the Papez circuit are correlated with insulin resistance in T2DM patients without mild cognitive impairment.

Wenqing Xia, Yu-Chen Chen, Yong Luo, Danfeng Zhang, Huiyou Chen, Jianhua Ma, Xindao Yin,

Insulin resistance (IR) can significantly affect the hippocampus, a component of a larger memory circuit called the Papez circuit. This study was performed to identify altered effective connectivity within the Papez circuit in type 2 diabetes mellitus (T2DM) patients without mild cognitive impairment (MCI) and to determine the relationships between ... Read more >>

Brain Imaging Behav (Brain imaging and behavior)
[2020, 14(4):1238-1246]

Cited: 1 time

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A Novel Immune-related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia

Shujuan Wang, Lu Yang, Yajun Liu, Yan Xu, Danfeng Zhang, Zhongxing Jiang, Chong Wang, Yanfang Liu,

<h4>Background: </h4> Acute myeloid leukemia is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow microenvironment. Infiltrated immune cells and stromal cells are an important part of the bone marrow microenvironment and significantly affect the progression of acute myeloid leukemia. Recently, the competing ... Read more >>

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Proteomic interrogation of antibiotic resistance and persistence in Escherichia coli - progress and potential for medical research.

Danfeng Zhang, Yuanqing Hu, Qiuqiang Zhu, Jiafu Huang, Yiyun Chen,

Introduction Escherichia coli strains possess two survival strategies to endure lethal antibiotic exposure including antibiotic resistance and persistence, in which persistence can contribute to the emergence of antibiotic resistance and increasing the risk of multidrug resistance. Using high-throughput proteomics for the comprehensive understanding of mechanisms of antibiotic resistance and persistence ... Read more >>

Expert Rev Proteomics (Expert review of proteomics)
[2020, 17(5):393-409]

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