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Author D Coghlan

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What does 'PEWing' or 'PEWsing' mean? A new word in paediatrics.

Catherine Diskin, Rachel MacDonell, Blaize Whelan, Orla O' Shea, John J Fitzsimons, David Vaughan, David Coghlan,

Arch Dis Child (Archives of disease in childhood)
[2020, 105(5):518-519]

Cited: 0 times

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Percutaneous endoscopic gastrostomy for refractory epilepsy and medication refusal.

Caoimhe Howard, William L Macken, Ann Connolly, Maria Keegan, David Coghlan, David W Webb,

OBJECTIVE:Current guidelines for percutaneous endoscopic gastrostomy (PEG) placement focus largely on maintaining enteral feeding when oral feeding is no longer possible or adequate with an emphasis on nutrition and quality of life (QOL). Previous publications have also alluded to potential benefits in medication adherence, for example, in children with HIV, ... Read more >>

Arch Dis Child (Archives of disease in childhood)
[2019, 104(7):690-692]

Cited: 1 time

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Influenza in Children: Is there a link with Medical Complications or Inflammatory Markers?

L Whilta, V Veitch, K O’Halloran, F O’Riordan, E Murphy, D Coghlan, B Elnazir, M Nadeem,

Ir Med J (Irish medical journal)
[2019, 112(4):925]

Cited: 0 times

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Blunted serum 25(OH)D response to vitamin D3 supplementation in children with autism.

Conor P Kerley, Basil Elnazir, Peter Greally, David Coghlan,

<b>Introduction:</b> Data suggest a potential role for vitamin D in autism spectrum disorder (ASD) prevention and treatment. It is likely that the serum response to vitamin D supplementation contributes to its effectiveness. Multiple factors affect serum vitamin D 25(OH)D response to supplementation. <b>Methods:</b> We conducted post-hoc analysis of two double-blind, ... Read more >>

Nutr Neurosci (Nutritional neuroscience)
[2020, 23(7):537-542]

Cited: 2 times

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Peripheral White Blood Cell Differential Counts In Children With UTI, Is There A Link?

E Rutledge, L Whitla, D Coghlan, M Nadeem,

Ir Med J (Irish medical journal)
[2018, 111(6):780]

Cited: 0 times

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Follow Up Chest Radiography In Paediatric Pneumonia: Is It Avoidable?

N Khan, L Whitla, M Kenosi, D Coghlan, M Nadeem,

Ir Med J (Irish medical journal)
[2018, 111(3):721]

Cited: 0 times

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20th Meeting of the Irish Society of Human Genetics : Friday 15th September 2017 Croke Park, Dublin

P Hynds, D Coghlan, C Purcell, A Green, A Ward, SA Lynch, O Hough, M Duff, N Cody, C Carroll, L Bradley, Andrew Green, Sally-Ann Lynch, SA Lynch, E Crushell, N Byrne, K Gorman, M King, A Irvine, A Monavari, I Knerr, M Cotter, V McConnell, A Green, F Browne, D Lambert, J Turner, J Casey, S Doyle, IM Nesbitt, M Fitzgibbon, SA Lynch, G Pastores, R Kirk, EP Treacy, KA Benson, C Kennedy, K Yachnin, G L Cavalleri, P Conlon, Úna M McVeigh, Terri P McVeigh, Nicola Miller, Derek W Morris, Michael J Kerin, R. Irwin, A. Caffrey, M. McLaughlin, H. McNulty, T. Cassidy, K. Pentieva, C. Walsh, S Minguzzi, A MacCooey, J Brosnan, M Brosnan, M Henry, P Meleady, A Parle-McDermott, EH Gilbert, S O’Reilly, M Merrigan, D McGettigan, AM Molloy, LC Brody, W Bodmer, K Hutnik, S Ennis, DJ Lawson, JF Wilson, GL Cavalleri, M Flynn, L Whitton, M Gill, A Corvin, G Donohoe, C Morrison, D Morris, CP. Stapleton, KA. Birdwell, PB. Mark, ML. Sanders, PJ. Phelan, AP. Maxwell, AJ. McKnight, C. Kennedy, A. Jardine, J.P Traynor, F. Chapman, B. Keating, PJ. Conlon, GL. Cavalleri, EA Gunne, A Ward, DM Lambert, SA Lynch, R Martin, DE Donnelly, MB Callaghan, DE Donnelly, PJ Morrison, DO McConville, GP Archbold, A Lewis, P J Morrison, S. Das, D. Kelly, B. Moran, E. Harold, K. Han, N. Mulligan, C. Barrett, P.G. Buckley, P. Mc Mahon, J McCaffrey, H. F. Van Essen, K. Connor, B. Ylstra, D. Lambrechts, W.M. Gallagher, D.P. O’Connor, C.M. Kelly, T O’Neill, C Power, E de Franco, S Ellard, SA Lynch, B Antao, SM O’Connell, V McConnell, T Dabir, S Heggarty, A Dockery, M Carrigan, N Wynne, D Keegan, K Stevenson, G Silvestri, A Green, J McCourt, P Humphries, PF. Kenna, GJ Farrar, R Agbahovbe, ASA Cohen, WT Gibson, AM Cole, R. Bohlender, H Hu, E Heinrich, C Ramirez, Y Yu, F Powell, E Gaio, F. Villafuerte, C Taylor, C Huff, T. Simonson, G. Cavalleri, C Scullion, R Irwin, A Thakur, C Walsh, C Shortall, A Palfi, N Chadderton, PF Kenna, M Carrigan, S Boomkamp, S Shen, AJ Hardcastle, GJ Farrar, DM Maloney, N Chadderton, S Millington-Ward, GJ Farrar, A Thakur, S-J Mackin, R E. Irwin, KM. O’Neill, G Pollin, C Walsh, L Whitton, G Apostolova, G Dechant, G Donohoe, D Morris, SJ Mackin, K O’Neill, CP Walsh, L Whitton, MNA Sohedein, G Donohoe, DW Morris, M Chaudhry, R Segurado, D Shields, AG Wilson, R.L. Watkin, O. Piskareva, S. Das, S. Madden, R. Stallings, S.W. Kerrigan, K M. O’Neill, R Irwin, SJ Mackin, A Thakur, SJ Thursby, C Bertens, L Masala, J Loughery, D McArt, CP Walsh, S. D. Amenyah, A. McMahon, J. Deane, M. Ward, H. McNulty, J.J. Strain, G. Horigan, J. Purvis, D. Lees-Murdock, SM. Lynch, M Ward, H McNulty, G Horigan, J.J. Strain, J Purvis, M Tackett, DJ. McKenna, Z Angel, CP. Walsh, DJ. McKenna,

Neurofibromatosis (NF1) affects 1/2500 people throughout the world. Children with NF1 require a multidisciplinary service ideally, delivered on a single site. NF1 is a very variable condition with children requiring the expertise of genetics, paediatricians, ophthalmologists, dermatologists, neurologists and other specialities as required. Building such a service concentrates expertise, facilitates ... Read more >>

Ulster Med J (The Ulster medical journal)
[2018, 87(1):54-64]

Cited: 0 times

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Vitamin D receptor variants and uncontrolled asthma.

K Hutchinson, C P Kerley, J Faul, P Greally, D Coghlan, M Louw, B Elnazir, Y Rochev,

Summary:Background. Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate the association between 2 VDR polymorphisms and uncontrolled paediatric asthma. Methods. 44 asthmatic children and 57 healthy volunteers ... Read more >>

Eur Ann Allergy Clin Immunol (European annals of allergy and clinical immunology)
[2018, 50(3):108-116]

Cited: 6 times

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Follow Up Chest Radiography In Paediatric Pneumonia: Is It Avoidable?

N Khan, L Whitla, M Kenosi, D Coghlan, M Nadeem,

Ir Med J (Irish medical journal)
[2018, 111(2):701]

Cited: 0 times

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Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin's Lymphoma.

Joseph M Connors, Wojciech Jurczak, David J Straus, Stephen M Ansell, Won S Kim, Andrea Gallamini, Anas Younes, Sergey Alekseev, Árpád Illés, Marco Picardi, Ewa Lech-Maranda, Yasuhiro Oki, Tatyana Feldman, Piotr Smolewski, Kerry J Savage, Nancy L Bartlett, Jan Walewski, Robert Chen, Radhakrishnan Ramchandren, Pier L Zinzani, David Cunningham, Andras Rosta, Neil C Josephson, Eric Song, Jessica Sachs, Rachael Liu, Hina A Jolin, Dirk Huebner, John Radford, ,

BACKGROUND:Brentuximab vedotin is an anti-CD30 antibody-drug conjugate that has been approved for relapsed and refractory Hodgkin's lymphoma. METHODS:We conducted an open-label, multicenter, randomized phase 3 trial involving patients with previously untreated stage III or IV classic Hodgkin's lymphoma, in which 664 were assigned to receive brentuximab vedotin, doxorubicin, vinblastine, and ... Read more >>

N Engl J Med (The New England journal of medicine)
[2018, 378(4):331-344]

Cited: 105 times

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Unpacking action research and implementation science: Implications for nursing.

Mary Casey, Denise O' Leary, David Coghlan,

<h4>Aim</h4>The aim of this study was to unpack the key concepts of action research and implementation science thereby enabling appropriate use of these methods in nursing.<h4>Background</h4>A key issue in action research is not so much the methodology employed to gather data/evidence but who decides the research agenda and who benefits ... Read more >>

J Adv Nurs (Journal of advanced nursing)
[2018, 74(5):1051-1058]

Cited: 4 times

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Interpretation of pyuria in children with urinary tract infection.

M Kenosi, L Whitla, N Khan, E Carty, D Coghlan, M Nadeem,

Acta Paediatr (Acta paediatrica (Oslo, Norway : 1992))
[2018, 107(2):358]

Cited: 0 times

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Lack of effect of vitamin D3 supplementation in autism: a 20-week, placebo-controlled RCT.

Conor P Kerley, Clare Power, Louise Gallagher, David Coghlan,

<h4>Objectives</h4>Data suggest a potential role for vitamin D in autism spectrum disorder (ASD). We wanted to assess the effect of vitamin D<sub>3</sub> supplementation compared with placebo in children with ASD.<h4>Design</h4>This was a double-blind, randomised, placebo-controlled trial.<h4>Setting</h4>A paediatric outpatient centre at high latitude over the winter season in Dublin, Ireland (53°N).<h4>Patients</h4>42 ... Read more >>

Arch Dis Child (Archives of disease in childhood)
[2017, 102(11):1030-1036]

Cited: 8 times

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Heart failure following blood cancer therapy in pediatric and adult populations.

Julie Franzon, Narelle M Berry, Shahid Ullah, Vincent L Versace, Alexandra L McCarthy, John Atherton, David Roder, Bogda Koczwara, Douglas Coghlan, Robyn A Clark,

<h4>Aim</h4>The link between chemotherapy treatment and cardiotoxicity is well established, particularly for adults with blood cancers. However, it is less clear for children. This analysis aimed to compare the trajectory and mortality of children and adults who received chemotherapy for blood cancers and were subsequently hospitalized for heart failure.<h4>Methods</h4>Linked data ... Read more >>

Asia Pac J Clin Oncol (Asia-Pacific journal of clinical oncology)
[2018, 14(3):224-230]

Cited: 1 time

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Life After the Event: A Review of Basic Life Support Training for Parents Following Apparent Life-Threatening Events and Their Experience and Practices Following Discharge.

W L Macken, N Clarke, M Nadeem, D Coghlan,

Apparent Life-Threatening Events (ALTEs) are a common presentation to paediatric hospitals and represent a significant cause of parental anxiety. Basic Life Support (BLS) training is recommended for all caregivers following ALTEs. This study aimed to assess the rate of caregiver BLS training and reviewed parents experience following discharge. Parents were ... Read more >>

Ir Med J (Irish medical journal)
[2017, 110(5):572]

Cited: 0 times

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Urinary Tract Infection in Childhood and Inflammatory Markers>.

S Tamgumus, J Geoghan, D Coghlan, M Nadeem,

Acute urinary tract infections are common in children. Our aim was to establish whether peripheral blood tests correlate with urinary culture. We also examined the relationship between peripheral blood results and the length of stay (LOS) in children and adolescents with UTI. We studied 135 patients admitted with UTI, mean ... Read more >>

Ir Med J (Irish medical journal)
[2016, 109(7):442]

Cited: 0 times

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Vitamin D3 for uncontrolled childhood asthma: A pilot study.

Conor P Kerley, Katrina Hutchinson, Liam Cormican, John Faul, Peter Greally, David Coghlan, Basil Elnazir,

<h4>Background</h4>Observational and mechanistic data suggest a role for vitamin D in childhood asthma. However, subsequent interventional trials have been inconsistent. We aimed to assess the effect of 15 weeks of vitamin D3 supplementation compared with placebo (PL) in Irish children with asthma.<h4>Methods</h4>We conducted a double-blind, randomized, PL-controlled trial of vitamin ... Read more >>

Pediatr Allergy Immunol (Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology)
[2016, 27(4):404-412]

Cited: 13 times

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Does this child really have a penicillin allergy?

K Murphy, B Scanlan, D Coghlan,

Penicillins, the most prescribed paediatric medications worldwide, are also the most commonly reported cause of medication allergy, although this is rarely confirmed. An oral penicillin challenge is considered the gold standard in assessing children with suspected allergy but is seldom performed due to lack of appropriately trained staff and insufficient ... Read more >>

Ir Med J (Irish medical journal)
[2015, 108(4):103, 105-6]

Cited: 0 times

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Understanding the challenges of palliative care in everyday clinical practice: an example from a COPD action research project.

Geralyn Hynes, Fiona Kavanagh, Christine Hogan, Kitty Ryan, Linda Rogers, Jenny Brosnan, David Coghlan,

Palliative care seeks to improve the quality of life for patients suffering from the impact of life-limiting illnesses. Palliative care encompasses but is more than end-of-life care, which is defined as care during the final hours/days/weeks of life. Although palliative care policies increasingly require all healthcare professionals to have at ... Read more >>

Nurs Inq (Nursing inquiry)
[2015, 22(3):249-260]

Cited: 3 times

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Special care dentistry: how prepared are we?

S Yeaton, A Moorthy, J Rice, D Coghlan, L O'Dwyer, E Green, A Sultan, S Guray, N A Mohamad, N Aslam, L Freedman,

<h4>Aim</h4>To assess and evaluate the confidence of the undergraduate dental team in Irish dental schools regarding their training in the field of special care dentistry (SCD).<h4>Method</h4>A questionnaire was distributed amongst the undergraduate dental teams within Cork University Dental School and Hospital (CUDSH) and Dublin Dental University Hospital (DDUH). The data ... Read more >>

Eur J Dent Educ (European journal of dental education : official journal of the Association for Dental Education in Europe)
[2016, 20(1):9-13]

Cited: 0 times

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Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma.

Lotfi Benboubker, Meletios A Dimopoulos, Angela Dispenzieri, John Catalano, Andrew R Belch, Michele Cavo, Antonello Pinto, Katja Weisel, Heinz Ludwig, Nizar Bahlis, Anne Banos, Mourad Tiab, Michel Delforge, Jamie Cavenagh, Catarina Geraldes, Je-Jung Lee, Christine Chen, Albert Oriol, Javier de la Rubia, Lugui Qiu, Darrell J White, Daniel Binder, Kenneth Anderson, Jean-Paul Fermand, Philippe Moreau, Michel Attal, Robert Knight, Guang Chen, Jason Van Oostendorp, Christian Jacques, Annette Ervin-Haynes, Hervé Avet-Loiseau, Cyrille Hulin, Thierry Facon, ,

<h4>Background</h4>The combination melphalan-prednisone-thalidomide (MPT) is considered a standard therapy for patients with myeloma who are ineligible for stem-cell transplantation. However, emerging data on the use of lenalidomide and low-dose dexamethasone warrant a prospective comparison of the two approaches.<h4>Methods</h4>We randomly assigned 1623 patients to lenalidomide and dexamethasone in 28-day cycles until ... Read more >>

N Engl J Med (The New England journal of medicine)
[2014, 371(10):906-917]

Cited: 298 times

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Infants with FPIES to solid food proteins--chicken, rice and oats.

K Cunningham, B Scanlan, D Coghlan, S Quinn,

We present two cases of Food Protein Induced Enterocolitis Syndrome (FPIES), a non-IgE mediated food hypersensitivity. FPIES induces severe vomiting 1.5-to-3 hours post ingestion of the offending food, and may be associated with diarrhoea, hypovolemic shock and acidosis. Avoidance of that food will lead to resolution of symptoms and prevents ... Read more >>

Ir Med J (Irish medical journal)
[2014, 107(5):151]

Cited: 0 times

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Acute leukaemia presenting with isolated bone pain.

Barry Scanlan, Montasser Nadeem, Martin Ryan, Owen Smith, Aengus O'Marcaigh, David Coghlan,

Arch Dis Child (Archives of disease in childhood)
[2013, 98(10):771]

Cited: 0 times

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Girl with xanthogranulomatous pyelonephritis and bronchiectasis: case report.

Montasser Nadeem, Oluwole A Oni, Martin Ryan, Prem Puri, David Coghlan, Peter Greally,

Xanthogranulomatous pyelonephritis (XGP) is a rare chronic inflammatory disorder of the kidney. Infiltration to lung and liver can occur. We present a rare complication of locally invasive XGP extending beyond the diaphragm to the lung to cause bronchiectasis in an adolescent girl with chronic productive cough, weight loss and no ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2013, 55(2):e17-9]

Cited: 1 time

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Oral rivaroxaban for the treatment of symptomatic pulmonary embolism.

, Harry R Büller, Martin H Prins, Anthonie W A Lensin, Hervé Decousus, Barry F Jacobson, Erich Minar, Jaromir Chlumsky, Peter Verhamme, Phil Wells, Giancarlo Agnelli, Alexander Cohen, Scott D Berkowitz, Henri Bounameaux, Bruce L Davidson, Frank Misselwitz, Alex S Gallus, Gary E Raskob, Sebastian Schellong, Annelise Segers,

BACKGROUND:A fixed-dose regimen of rivaroxaban, an oral factor Xa inhibitor, has been shown to be as effective as standard anticoagulant therapy for the treatment of deep-vein thrombosis, without the need for laboratory monitoring. This approach may also simplify the treatment of pulmonary embolism. METHODS:In a randomized, open-label, event-driven, noninferiority trial ... Read more >>

N Engl J Med (The New England journal of medicine)
[2012, 366(14):1287-1297]

Cited: 899 times

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