Full Text Journal Articles by
Author Cristina Risco

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Ins and Outs of Reovirus: Vesicular Trafficking in Viral Entry and Egress.

Alexa N Roth, Pavithra Aravamudhan, Isabel Fernández de Castro, Raquel Tenorio, Cristina Risco, Terence S Dermody,

Cell entry and egress are essential steps in the viral life cycle that govern pathogenesis and spread. Mammalian orthoreoviruses (reoviruses) are nonenveloped viruses implicated in human disease that serve as tractable models for studies of pathogen-host interactions. In this review we discuss the function of intracellular vesicular transport systems in ... Read more >>

Trends Microbiol (Trends in microbiology)
[2020, :]

Cited: 0 times

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Pilot randomized controlled trial of a Spanish-language Behavioral Activation mobile app (¡Aptívate!) for the treatment of depressive symptoms among united states Latinx adults with limited English proficiency.

Jennifer Dahne, Anahi Collado, C W Lejuez, Cristina M Risco, Vanessa A Diaz, Lisa Coles, Jacob Kustanowitz, Michael J Zvolensky, Matthew J Carpenter,

BACKGROUND:To address the need for disseminable, evidence-based depression treatment options for Latinx adults with limited English proficiency (LEP), our team developed ¡Aptívate!, a Spanish-language Behavioral Activation self-help mobile application. Primary aims of this study were to: 1) examine feasibility and uptake of ¡Aptívate! among depressed Latinx adults with LEP and ... Read more >>

J Affect Disord (Journal of affective disorders)
[2019, 250:210-217]

Cited: 1 time

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¡Aptívate!: A Spanish-language behavioral activation mobile application for delivery via primary care.

Jennifer Dahne, Anahi Collado, C W Lejuez, Cristina Risco, Vanessa A Diaz, Jacob Kustanowitz, Michael Zvolensky, Matthew J Carpenter,

Treatment for depression is a core health disparity for Latino/as in the United States. U.S. Latino/as are most likely to report depressive symptoms to primary care physicians, who often have limited resources for providing evidence-based psychological depression treatment. This limited treatment accessibility is further compounded by additional treatment barriers, including ... Read more >>

Psychol Serv (Psychological services)
[2019, 16(2):271-275]

Cited: 2 times

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Metal-Tagging Transmission Electron Microscopy and Immunogold Labeling on Tokuyasu Cryosections to Image Influenza A Virus Ribonucleoprotein Transport and Packaging.

Martin Sachse, Isabel Fernández de Castro, Guillaume Fournier, Nadia Naffakh, Cristina Risco,

Transmission electron microscopy (TEM) has been instrumental for studying viral infections. In particular, methods for labeling macromolecules at the ultrastructural level, by integrating biochemistry, molecular biology, and morphology, have allowed to study the functions of viral macromolecular complexes within the cellular context. Here, we describe a strategy for imaging influenza ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2018, 1836:281-301]

Cited: 1 time

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Evaluation of the Environmental Supports Scale with a Community Sample of Adolescents.

Cristina M Risco, Anahi D Collado, Elizabeth K Reynolds, Carl W Lejuez, Laura MacPherson,

Environmental sources of psychosocial support have been found to modulate or protect against the development of psychopathology and risk behavior among adolescents. Capturing sources of environmental support across multiple developmental contexts requires the availability of well-validated, concise assessments-of which there are few in the existing literature. In order to address ... Read more >>

Prev Sci (Prevention science : the official journal of the Society for Prevention Research)
[2016, 17(4):493-502]

Cited: 1 time

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Three-dimensional imaging of the intracellular assembly of a functional viral RNA replicase complex.

Isabel Fernández de Castro, José J Fernández, Daniel Barajas, Peter D Nagy, Cristina Risco,

Positive-strand RNA viruses, which can be devastating pathogens in humans, animals and plants, replicate their genomes on intracellular membranes. Here, we describe the three-dimensional ultrastructural organization of a tombusvirus replicase in yeast, a valuable model for exploring virus-host interactions. We visualized the intracellular distribution of a viral replicase protein using ... Read more >>

J. Cell. Sci. (Journal of cell science)
[2017, 130(1):260-268]

Cited: 24 times

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Virus assembly factories in a lipid world.

Isabel Fernández de Castro, Raquel Tenorio, Cristina Risco,

Many viruses build specialized structures known as viral factories, a protected environment in which viral genome replication and morphogenesis take place. Recent findings show that viruses manipulate lipid flows to assemble these replication platforms. Viruses are thus able to create new membranes by interfering with lipid metabolism, targeting and transport; ... Read more >>

Curr Opin Virol (Current opinion in virology)
[2016, 18:20-26]

Cited: 19 times

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Three-Dimensional Imaging of Viral Infections.

Cristina Risco, Isabel Fernández de Castro, Laura Sanz-Sánchez, Kedar Narayan, Giovanna Grandinetti, Sriram Subramaniam,

Three-dimensional (3D) imaging technologies are beginning to have significant impact in the field of virology, as they are helping us understand how viruses take control of cells. In this article we review several methodologies for 3D imaging of cells and show how these technologies are contributing to the study of ... Read more >>

Annu Rev Virol (Annual review of virology)
[2014, 1(1):453-473]

Cited: 17 times

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Brief report: The interaction of impulsivity with risk-taking is associated with early alcohol use initiation.

Kristen R Hamilton, Julia W Felton, Cristina M Risco, C W Lejuez, Laura MacPherson,

Early alcohol use initiation is a well-established risk factor for the subsequent development of alcohol abuse and dependence. Separate lines of research indicate that impulsivity and risk-taking each are associated with early alcohol use. In this research, the association of the interaction of risk-taking and impulsivity with early alcohol initiation ... Read more >>

J Adolesc (Journal of adolescence)
[2014, 37(8):1253-1256]

Cited: 7 times

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Metallothioneins for correlative light and electron microscopy.

Isabel Fernández de Castro, Laura Sanz-Sánchez, Cristina Risco,

Structural biologists have been working for decades on new strategies to identify proteins in cells unambiguously. We recently explored the possibilities of using the small metal-binding protein, metallothionein (MT), as a tag to detect proteins in transmission electron microscopy. It had been reported that, when fused with a protein of ... Read more >>

Methods Cell Biol (Methods in cell biology)
[2014, 124:55-70]

Cited: 8 times

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Cultural adaptation and individual tailoring: two approaches to the development of culturally responsive treatment.

Anahi Collado, Laura Macpherson, Cristina Risco, C W Lejuez,

Prim Care Companion CNS Disord (The primary care companion for CNS disorders)
[2013, 15(5):]

Cited: 1 time

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Self-protection and survival of arbovirus-infected mosquito cells.

Noelia López-Montero, Cristina Risco,

Arboviruses are serious pathogens for men but cause little damage to their arthropod vectors. We have studied how a mosquito cell line derived from one of the relevant vectors for arboviruses responds to Bunyamwera virus, a well-characterized arbovirus. Confocal, live cell microscopy and electron microscopy showed that Bunyamwera virus induces ... Read more >>

Cell. Microbiol. (Cellular microbiology)
[2011, 13(2):300-315]

Cited: 10 times

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The coat protein of Rabbit hemorrhagic disease virus contains a molecular switch at the N-terminal region facing the inner surface of the capsid.

Juan Bárcena, Nuria Verdaguer, Ramón Roca, Mónica Morales, Iván Angulo, Cristina Risco, José L Carrascosa, Juan M Torres, José R Castón,

To function adequately, many if not all proteins involved in macromolecular assemblies show conformational polymorphism as an intrinsic feature. This general strategy has been described for many essential cellular processes. Here we describe this structural polymorphism in a viral protein, the coat protein of Rabbit hemorrhagic disease virus (RHDV), which ... Read more >>

Virology (Virology)
[2004, 322(1):118-134]

Cited: 33 times

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Multiple regulatory mechanisms act on the 5' untranslated region of the S-layer gene from Thermus thermophilus HB8.

P Castán, M A de Pedro , C Risco, C Vallés, L A Fernández, H Schwarz, J Berenguer,

The role of the 5' untranslated region (5'UTR) of the S-layer gene from Thermus thermophilus was analyzed through the isolation of Delta 5'UTR mutants. In these mutants the half-life of splA mRNA was strongly reduced and slpA transcription was no longer subjected to growth phase-dependent repression. Overproduction and detachment of ... Read more >>

J. Bacteriol. (Journal of bacteriology)
[2001, 183(4):1491-1494]

Cited: 10 times

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Cooperation between transmissible gastroenteritis coronavirus (TGEV) structural proteins in the in vitro induction of virus-specific antibodies.

I M Antón, S González, M J Bullido, M Corsín, C Risco, J P Langeveld, L Enjuanes,

Following infection of haplotype defined NIH-miniswine with virulent transmissible gastroenteritis coronavirus (TGEV), isolated mesenteric lymph node CD4+ T-cells mounted a specific proliferative response against infectious or inactivated purified virus in secondary in vitro stimulation. A specific, dose-dependent response to the three major recombinant viral proteins: spike (S), membrane (M), and ... Read more >>

Virus Res. (Virus research)
[1996, 46(1-2):111-124]

Cited: 27 times

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