Full Text Journal Articles by
Author Cristina Bosetti

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Factors for Timely Identification of Possible Occurrence of Delirium in Palliative Care: A Prospective Observational Study.

Oscar Corli, Claudia Santucci, Sara Uggeri, Cristina Bosetti, Matteo Cattaneo, Daniela Ermolli, Giustino Varrassi, Dariusz Myrcik, Antonella Paladini, Martina Rekatsina, Cristiana Gerosa, Martina Ornaghi, Alessandra Roccasalva, Paola Santambrogio, Matteo Beretta,

Delirium occurs in 50-80% of end-of-life patients but is often misdiagnosed. Identification of clinical factors potentially associated with delirium onset can lead to a correct early diagnosis. To this aim, we conducted a prospective cohort study on patients from an Italian palliative care unit (PCU) admitted in 2018-2019. We evaluated ... Read more >>

Adv Ther (Advances in therapy)
[2021, :]

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The role of diet on the risk of dementia in the oldest old: The Monzino 80-plus population-based study.

Cristina Nicoli, Alessia Antonella Galbussera, Cristina Bosetti, Carlotta Franchi, Silvano Gallus, Sara Mandelli, Gabriella Marcon, Pierluigi Quadri, Patrizia Riso, Emma Riva, Ugo Lucca, Mauro Tettamanti,

<h4>Background & aims</h4>Longevity also carries its dark side of age-related chronic diseases, dementia being one of the worst and the most prevalent. Since dementia lacks effective treatments, preventing or delaying it is highly desirable. Dietary habits and nutrition have been found to be important modifiable risk factors for many chronic ... Read more >>

Clin Nutr (Clinical nutrition (Edinburgh, Scotland))
[2021, 40(7):4783-4791]

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Coffee consumption and colorectal cancer risk: a multicentre case-control study from Italy and Spain.

Valentina Rosato, Valentina Guercio, Cristina Bosetti, Esther Gracia-Lavedan, Cristina M Villanueva, Jerry Polesel, Federica Toffoluti, Victor Moreno, Vicente Martin, Nuria Aragonés, Trinidad Dierssen-Sotos, Rocío Olmedo-Requena, Marcela Guevara, Pilar Amiano, Dolores Salas, Guillermo Fernandez-Tardon, Juan Alguacil, María Dolores Chirlaque López, Tania Fernandez-Villa, Beatriz Pérez-Gómez, Ines Gomez-Acebo, Jose J Jiménez-Moleón, Conchi Moreno-Iribas, Antonio José Molina, Gemma Castaño Vinyals, Marina Pollan, Manolis Kogevinas, Carlo La Vecchia, Alessandra Tavani,

<h4>Background</h4>Coffee contains many bioactive substances that can play a role on colorectal cancer. Epidemiological evidence of coffee intake and colorectal cancer is, however, inconsistent.<h4>Aim</h4>To provide further information on the risk of colorectal cancer in relation to coffee consumption.<h4>Methods</h4>Data derive from two companion case-control studies conducted in Italy and Spain within ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, 30(3):204-210]

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Risk Factors for Olfactory and Gustatory Dysfunctions in Patients with SARS-CoV-2 Infection.

Francesca Galluzzi, Veronica Rossi, Cristina Bosetti, Werner Garavello,

<h4>Introduction</h4>Smell and taste loss are characteristic symptoms of SARS-CoV-2 infection. The aim of this study is to investigate the prevalence and risk factors associated with olfactory and gustatory dysfunctions in coronavirus disease (COVID-19) patients.<h4>Methods</h4>We conducted an observational, retrospective study on 376 patients with documented SARS-CoV-2 infection admitted to the San ... Read more >>

Neuroepidemiology (Neuroepidemiology)
[2021, 55(2):154-161]

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Factors for a Timely Identification of Possible Occurrence of Delirium in Palliative Care: A Prospective Observational Study

Oscar Corli, Claudia Santucci, Sara Uggeri, Cristina Bosetti, Matteo Cattaneo, Daniela Ermolli, Giustino Varrassi, Dariusz Myrcik, Cristiana Gerosa, Martina Ornaghi, Alessandra Roccasalva, Paola Santambrogio, Matteo Beretta,

Delirium occurs in 50-80% of end-of-life patients but it is often misdiagnosed. Identification of clinical factors potentially associated with delirium onset can lead to a correct early diagnosis. To this aim, we conducted an observational prospective study on patients from an Italian Palliative Care Unit (PCU) in 2018-2019 and evaluated ... Read more >>

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Use of preventive drugs during the last year of life in older adults with cancer or chronic progressive diseases.

Cristina Bosetti, Claudia Santucci, Luca Pasina, Ida Fortino, Luca Merlino, Oscar Corli, Alessandro Nobili,

<h4>Purpose</h4>To evaluate the prescription of preventive medications with questionable usefulness in community dwelling elderly adults with cancer or chronic progressive diseases during the last year of life.<h4>Methods</h4>Through the utilization of the healthcare databases of the Lombardy region, Italy, we identified two retrospective cohorts of patients aged 65 years or more, who ... Read more >>

Pharmacoepidemiol Drug Saf (Pharmacoepidemiology and drug safety)
[2021, 30(8):1057-1065]

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Effect of fructose instead of glucose or sucrose on cardiometabolic markers: a systematic review and meta-analysis of isoenergetic intervention trials.

Elena Fattore, Francesca Botta, Cristina Bosetti,

<h4>Context</h4>Free, or added, sugars are considered important determinants in the pandemics of obesity and associated chronic diseases, and fructose has emerged as the sugar of main concern.<h4>Objective</h4>The aim of this review was to assess the evidence of the effects of isoenergetic replacement of fructose or high-fructose corn syrup (HFCS) for ... Read more >>

Nutr Rev (Nutrition reviews)
[2021, 79(2):209-226]

Cited: 1 time

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Risk of COVID 19 in patients with inflammatory bowel diseases compared to a control population.

Giovanni Maconi, Cristina Bosetti, Alberta De Monti, Ray Kiran Boyapati, Edward Shelton, Nicole Piazza, Anna Maria Carvalhas Gabrielli, Marco Vincenzo Lenti, Cristina Bezzio, Chiara Ricci, Salvatore Greco, Samanta Romeo, Francesco Giangregorio, Daniele Gridavilla, Fabio Tagliani, Alessandro Massari, Luca Pastorelli, Antonio Di Sabatino, Simone Saibeni, Saverio Alicante, Francesca Ferretti, Giuliano Rizzardini, Massimo Galli, Sandro Ardizzone,

<h4>Background</h4>It is unclear whether patients with inflammatory bowel disease (IBD) are at increased risk of COVID-19.<h4>Objectives</h4>This observational study compared the prevalence of COVID-19 symptoms, diagnosis and hospitalization in IBD patients with a control population with non-inflammatory bowel disorders.<h4>Methods</h4>This multicentre study, included 2733 outpatients (1397 IBD patients and 1336 controls), from ... Read more >>

Dig Liver Dis (Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver)
[2021, 53(3):263-270]

Cited: 2 times

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National burden of cancer in Italy, 1990-2017: a systematic analysis for the global burden of disease study 2017.

Cristina Bosetti, Eugenio Traini, Tahiya Alam, Christine A Allen, Giulia Carreras, Kelly Compton, Christina Fitzmaurice, Lisa M Force, Silvano Gallus, Giuseppe Gorini, James D Harvey, Jonathan M Kocarnik, Carlo La Vecchia, Alessandra Lugo, Mohsen Naghavi, Alyssa Pennini, Cristiano Piccinelli, Luca Ronfani, Rixing Xu, Lorenzo Monasta,

We monitored the burden of cancer in Italy and its trends over the last three decades, providing estimates of cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years (DALYs), for cancer overall and 30 cancer sites using data from the Global Burden of Disease study ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):22099]

Cited: 2 times

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Smoking and Colorectal Cancer Risk, Overall and by Molecular Subtypes: A Meta-Analysis.

Edoardo Botteri, Elisa Borroni, Erica K Sloan, Vincenzo Bagnardi, Cristina Bosetti, Giulia Peveri, Claudia Santucci, Claudia Specchia, Piet van den Brandt, Silvano Gallus, Alessandra Lugo,

<h4>Introduction</h4>The aim of this study was to provide the most comprehensive and up-to-date evidence on the association between cigarette smoking and colorectal cancer (CRC) risk.<h4>Methods</h4>We conducted a systematic review and meta-analysis of epidemiological studies on the association between cigarette smoking and CRC risk published up to September 2018. We calculated ... Read more >>

Am J Gastroenterol (The American journal of gastroenterology)
[2020, 115(12):1940-1949]

Cited: 3 times

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Impact of Palliative Care in Evaluating and Relieving Symptoms in Patients with Advanced Cancer. Results from the DEMETRA Study.

Oscar Corli, Giacomo Pellegrini, Cristina Bosetti, Luca Riva, Matteo Crippa, Emanuele Amodio, Gianlorenzo Scaccabarozzi,

<i>Background:</i> Cancer patients experience multiple symptoms throughout the course of the disease. We aimed to provide a comprehensive analysis of the symptom burden in patients with advanced cancer at admission to specialist palliative care (PC) services and seven days later to estimate the immediate impact of PC intervention. <i>Patient and ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(22):]

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Aspirin and the risk of nondigestive tract cancers: An updated meta-analysis to 2019.

Claudia Santucci, Silvano Gallus, Marco Martinetti, Carlo La Vecchia, Cristina Bosetti,

Aspirin has been associated with a reduced risk of colorectal and other selected digestive tract cancers, but the evidence for other neoplasms is still controversial. To provide an up-to-date quantification of the role of aspirin on lung, breast, endometrium, ovary, prostate, bladder, and kidney cancer, we conducted a systematic review ... Read more >>

Int J Cancer (International journal of cancer)
[2021, 148(6):1372-1382]

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Gallbladder disease, cholecystectomy, and pancreatic cancer risk in the International Pancreatic Cancer Case-Control Consortium (PanC4).

Valentina Rosato, Eva Negri, Cristina Bosetti, Núria Malats, Paulina Gomez-Rubio, PanGenEU Consortium, Patrick Maisonneuve, Anthony B Miller, H Bas Bueno-de-Mesquita, Peter A Baghurst, Witold Zatonski, Gloria M Petersen, Ghislaine Scelo, Ivana Holcatova, Eleonora Fabianova, Diego Serraino, Sara H Olson, Jesús Vioque, Pagona Lagiou, Eric J Duell, Paolo Boffetta, Carlo La Vecchia,

<h4>Background</h4>The association among gallbladder disease, cholecystectomy, and pancreatic cancer is unclear. Moreover, time interval between gallbladder disease or cholecystectomy and pancreatic cancer diagnosis is not considered in most previous studies.<h4>Aim</h4>To quantify the association among gallbladder disease, cholecystectomy, and pancreatic cancer, considering time since first diagnosis of gallbladder disease or cholecystectomy.<h4>Methods</h4>We ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2020, 29(5):408-415]

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Progress in cancer mortality, incidence, and survival: a global overview.

Claudia Santucci, Greta Carioli, Paola Bertuccio, Matteo Malvezzi, Ugo Pastorino, Paolo Boffetta, Eva Negri, Cristina Bosetti, Carlo La Vecchia,

Cancer mortality has declined over the last three decades in most high-income countries reflecting improvements in cancer prevention, diagnosis, and management. However, there are persisting and substantial differences in mortality, incidence, and survival worldwide. In order to provide an up-to-date overview of trends in mortality, incidence, and survival, we retrieved ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2020, 29(5):367-381]

Cited: 5 times

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Impact of Palliative Care in Evaluating and Relieving Symptoms in Patients with Advanced Cancer. The DEMETRA Study

Oscar Corli, Giacomo Pellegrini, Cristina Bosetti, Luca Riva, Matteo Crippa, Gianlorenzo Scaccabarozzi,

<h4>Background: </h4> Cancer patients experience a number of symptoms throughout the course of the disease. We aimed to provide a comprehensive analysis of the symptom burden in patients with advanced cancer at admission to specialist palliative care (PC) services and seven days later, to estimate the immediate impact of PC ... Read more >>

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Covid-19 and the role of smoking: the protocol of the multicentric prospective study COSMO-IT (COvid19 and SMOking in ITaly).

Maria Sofia Cattaruzza, Giuseppe Gorini, Cristina Bosetti, Roberto Boffi, Alessandra Lugo, Chiara Veronese, Giulia Carreras, Claudia Santucci, Chiara Stival, Roberta Pacifici, Vincenzo Zagà, Silvano Gallus, Federico Giulietti, Riccardo Sarzani, Francesco Spannella, Mario Del Donno, Stefania Tartaglione, Giuseppina Marrazzo, Girolamo Pelaia, Vincenzo D'Agosto, Alice Berti, Fabio Voller, Salvatore Cardellicchio, Chiara Cresci, Maria Pia Foschino Barbaro, Raffaele De Palma, Simone Negrini, Vera Sicbaldi, Antonella Serafini, Mario Bisconti, Leonida Refolo, Giovanni Landoni, Patrizia Rovere, Giulia Veronesi, Paola Faverio, Werner Garavello, Alberto Pesci, Raffaella Giacobbe, Paola Martucci, Roberto Parrella, Francesco Scarano, Marina Aiello, Alfredo Chetta, Cosimo Franco, Angelo Mangia, Laura Carrozzi, Fabrizio Maggi, Fabio Monzani, Francesco Pistelli, Patrizia Russo, Antonio Sanna, Filippo Maria Barreca, Valentina Conti, Enrico Rossi, Mei Ruli, Silvana Ruli, Shokoofe Eslami Varzaneh, Rosastella Principe, Simone Guerrini, Alfredo Sebastiani, Giovanni Galluccio, Aldo Pezzuto, Alberto Ricci, Elena Casali, Claudio Mastroianni, Pietro Pirina, Francesca Polo, Fabio Beatrice, Micaela Romagnoli, Massimo Baraldo, Pier Giorgio Cojutti, Carlo Tascini, Davide Pecori, Elena Graziano, Biagio Tinghino,

The emergency caused by Covid-19 pandemic raised interest in studying lifestyles and comorbidities as important determinants of poor Covid-19 prognosis. Data on tobacco smoking, alcohol consumption and obesity are still limited, while no data are available on the role of e-cigarettes and heated tobacco products (HTP). To clarify the role ... Read more >>

Acta Biomed (Acta bio-medica : Atenei Parmensis)
[2020, 91(3):e2020062]

Cited: 2 times

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COVID-19 lockdown impact on lifestyle habits of Italian adults.

Anna Odone, Alessandra Lugo, Andrea Amerio, Elisa Borroni, Cristina Bosetti, Giulia Carreras, Luca Cavalieri d'Oro, Paolo Colombo, Tiziana Fanucchi, Simone Ghislandi, Giuseppe Gorini, Licia Iacoviello, Roberta Pacifici, Claudia Santucci, Gianluca Serafini, Carlo Signorelli, Chiara Stival, David Stuckler, Carlo Alberto Tersalvi, Silvano Gallus,

In March 2020, when the Government imposed nation-wide lockdown measures to contrast the COVID-19 outbreak, the life of Italians suddenly changed. In order to evaluate the impact of lockdown on lifestyle habits and behavioral risk factors of the general adult population in Italy, we set up the Lost in Italy ... Read more >>

Acta Biomed (Acta bio-medica : Atenei Parmensis)
[2020, 91(9-S):87-89]

Cited: 9 times

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Detection of TP53 Clonal Variants in Papanicolaou Test Samples Collected up to 6 Years Prior to High-Grade Serous Epithelial Ovarian Cancer Diagnosis.

Lara Paracchini, Chiara Pesenti, Martina Delle Marchette, Luca Beltrame, Tommaso Bianchi, Tommaso Grassi, Alessandro Buda, Fabio Landoni, Lorenzo Ceppi, Cristina Bosetti, Mariachiara Paderno, Marco Adorni, Debora Vicini, Patrizia Perego, Biagio Eugenio Leone, Maurizio D'Incalci, Sergio Marchini, Robert Fruscio,

<h4>Importance</h4>The low 5-year survival rate of women with high-grade serous epithelial ovarian cancer (HGS-EOC) is related to its late diagnosis; thus, improvement in diagnosis constitutes a crucial step to increase the curability of this disease.<h4>Objective</h4>To determine whether the presence of the clonal pathogenic TP53 variant detected in matched primary tumor ... Read more >>

JAMA Netw Open (JAMA network open)
[2020, 3(7):e207566]

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Histologic subtyping affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis.

Francesca Sanges, Matteo Floris, Paolo Cossu-Rocca, Maria R Muroni, Giovanna Pira, Silvana Anna Maria Urru, Renata Barrocu, Silvano Gallus, Cristina Bosetti, Maurizio D'Incalci, Alessandra Manca, Maria Gabriela Uras, Ricardo Medda, Elisabetta Sollai, Alma Murgia, Dolores Palmas, Francesco Atzori, Angelo Zinellu, Francesca Cambosu, Tiziana Moi, Massimo Ghiani, Vincenzo Marras, Maria Cristina Santona, Luisa Canu, Enrichetta Valle, Maria Giuseppina Sarobba, Daniela Onnis, Anna Asunis, Sergio Cossu, Sandra Orrù, Maria Rosaria De Miglio,

<h4>Background</h4>Triple Negative breast cancer (TNBC) includes a heterogeneous group of tumors with different clinico-pathological features, molecular alterations and treatment responsivity. Our aim was to evaluate the clinico-pathological heterogeneity and prognostic significance of TNBC histologic variants, comparing "special types" to high-grade invasive breast carcinomas of no special type (IBC-NST).<h4>Methods</h4>This study was ... Read more >>

BMC Cancer (BMC cancer)
[2020, 20(1):491]

Cited: 1 time

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A data mining approach to investigate food groups related to incidence of bladder cancer in the BLadder cancer Epidemiology and Nutritional Determinants International Study.

Evan Y W Yu, Anke Wesselius, Christoph Sinhart, Alicja Wolk, Mariana Carla Stern, Xuejuan Jiang, Li Tang, James Marshall, Eliane Kellen, Piet van den Brandt, Chih-Ming Lu, Hermann Pohlabeln, Gunnar Steineck, Mohamed Farouk Allam, Margaret R Karagas, Carlo La Vecchia, Stefano Porru, Angela Carta, Klaus Golka, Kenneth C Johnson, Simone Benhamou, Zuo-Feng Zhang, Cristina Bosetti, Jack A Taylor, Elisabete Weiderpass, Eric J Grant, Emily White, Jerry Polesel, Maurice P A Zeegers,

At present, analysis of diet and bladder cancer (BC) is mostly based on the intake of individual foods. The examination of food combinations provides a scope to deal with the complexity and unpredictability of the diet and aims to overcome the limitations of the study of nutrients and foods in ... Read more >>

Br J Nutr (The British journal of nutrition)
[2020, 124(6):611-619]

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Who Smokes in Europe? Data From 12 European Countries in the TackSHS Survey (2017-2018).

Silvano Gallus, Alessandra Lugo, Xiaoqiu Liu, Panagiotis Behrakis, Roberto Boffi, Cristina Bosetti, Giulia Carreras, Liliane Chatenoud, Luke Clancy, Xavier Continente, Ruaraidh Dobson, Tobias Effertz, Filippos T Filippidis, Marcela Fu, Gergana Geshanova, Giuseppe Gorini, Sheila Keogan, Hristo Ivanov, María J Lopez, Angel Lopez-Nicolas, José Precioso, Krzysztof Przewozniak, Cornel Radu-Loghin, Ario Ruprecht, Sean Semple, Joan B Soriano, Polina Starchenko, Marta Trapero-Bertran, Olena Tigova, Anna S Tzortzi, Constantine Vardavas, Vergina K Vyzikidou, Paolo Colombo, Esteve Fernandez, ,

<h4>Background</h4>Population data on tobacco use and its determinants require continuous monitoring and careful inter-country comparison. We aimed to provide the most up-to-date estimates on tobacco smoking from a large cross-sectional survey, conducted in selected European countries.<h4>Methods</h4>Within the TackSHS Project, a face-to-face survey on smoking was conducted in 2017-2018 in 12 ... Read more >>

J Epidemiol (Journal of epidemiology)
[2021, 31(2):145-151]

Cited: 3 times

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The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

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<h4>Background</h4>Oesophageal cancer is a common and often fatal cancer that has two main histological subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma. Updated statistics on the incidence and mortality of oesophageal cancer, and on the disability-adjusted life-years (DALYs) caused by the disease, can assist policy makers in allocating resources for ... Read more >>

Lancet Gastroenterol Hepatol (The lancet. Gastroenterology & hepatology)
[2020, 5(6):582-597]

Cited: 15 times

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Exposure to secondhand aerosol of electronic cigarettes in indoor settings in 12 European countries: data from the TackSHS survey.

Beladenta Amalia, Xiaoqiu Liu, Alessandra Lugo, Marcela Fu, Anna Odone, Piet A van den Brandt, Sean Semple, Luke Clancy, Joan B Soriano, Esteve Fernández, Silvano Gallus, ,

<h4>Introduction</h4>Exposure to secondhand aerosol from e-cigarette (SHA) may pose harmful effects to bystanders. This study aims to investigate the prevalence, duration and determinants of SHA exposure in various indoor settings in 12 European countries.<h4>Methods</h4>In 2017-2018, we conducted a cross-sectional study, the TackSHS survey, on a representative sample of the population ... Read more >>

Tob Control (Tobacco control)
[2021, 30(1):49-56]

Cited: 1 time

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The Complex Balance between Analgesic Efficacy, Change of Dose and Safety Profile Over Time, in Cancer Patients Treated with Opioids: Providing the Clinicians with an Evaluation Tool.

Oscar Corli, Luca Porcu, Claudia Santucci, Cristina Bosetti,

BACKGROUND:Scanty data exist on the integration between the analgesic effect of opioids, dose changes, and adverse events in cancer patients. METHODS:To provide further information on this issue, we analysed data on 498 advanced-stage cancer patients treated with strong opioids. At baseline and three visits (at days 7, 14, and 21), ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(2):]

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Global trends in oral and pharyngeal cancer incidence and mortality.

Cristina Bosetti, Greta Carioli, Claudia Santucci, Paola Bertuccio, Silvano Gallus, Werner Garavello, Eva Negri, Carlo La Vecchia,

To provide an up-to-date overview of recent trends in mortality from oral and pharyngeal cancer, we analyzed death certification data for 61 countries worldwide provided by the World Health Organization in 2010-2015, and, for selected most populous countries, over the period 1970-2016. For 12 largest countries, we analyzed incidence derived ... Read more >>

Int J Cancer (International journal of cancer)
[2020, 147(4):1040-1049]

Cited: 4 times

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