Full Text Journal Articles by
Author Corina Iorgoveanu

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Methylenetetrahydrofolate Reductase Polymorphism and Premature Coronary Artery Disease.

Ahmed Zaghloul, Corina Iorgoveanu, Aakash Desai, Kathir Balakumaran, Kai Chen,

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine re-methylation to methionine. Its deficiency leads to an increased serum level of homocysteine, which is well-known to be associated with premature coronary artery disease (CAD). Our case demonstrates the association of MTHFR polymorphism with premature CAD ... Read more >>

Cureus (Cureus)
[2019, 11(6):e5014]

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Secondary Immune Thrombocytopenic Purpura in Renal Cell Cancer: A Paraneoplastic Syndrome.

Arish Noor, Anam Rehan, Aakash Desai, Corina Iorgoveanu, Jim C Lee,

Secondary immune thrombocytopenic purpura (ITP) as a paraneoplastic syndrome has been reported in literature. It is commonly associated with chronic lymphocytic leukemia (CLL) and hodgkins lymphoma. Its association with solid malignancies, especially renal cell cancer is rare, with only a few documented case reports. Treatment usually consisted of targeting the underlying malignancy ... Read more >>

Cureus (Cureus)
[2019, 11(4):e4398]

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Atypical Arrhythmia Associated with Lithium Therapy: When to Expect the Unexpected?

Corina Iorgoveanu, Ahmed Zaghloul, Teodora Donisan, Dinu Valentin Balanescu, Kathir Balakumaran, Serban Mihai Balanescu,

Acta Cardiol Sin (Acta Cardiologica Sinica)
[2019, 35(2):179-182]

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Hypertensive Crisis in Cardiac Tamponade.

Corina Iorgoveanu, Ahmed Zaghloul, Aakash Desai, Kathir Balakumaran, Kai Chen,

Cardiac tamponade is a potentially life-threatening disorder believed to be commonly associated with hypotension and even shock. However, many patients with subacute tamponade are indeed hypertensive at initial presentation. We present a case of a 76-year-old female with hypertensive crisis in the settings of cardiac tamponade whose blood pressure normalized after ... Read more >>

Cureus (Cureus)
[2018, 10(6):e2873]

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Prosthetic Tricuspid Valve Thrombosis.

Ahmed Zaghloul, Corina Iorgoveanu, Aakash Desai, Molly Silkowski, Kathir Balakumaran,

Prosthetic valve thrombosis, a serious complication of prosthetic valve replacement, can be lethal without proper treatment. Right-sided valve thrombosis is rare but several therapeutic modalities can be considered: anticoagulation therapy, fibrinolysis, or surgery. Here, we report a case of significant tricuspid valve thrombosis which failed fibrinolytic therapy requiring repeat sternotomy with repeat ... Read more >>

Cureus (Cureus)
[2018, 10(7):e2928]

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Limitations of Coronary Computed Tomography Angiography in Predicting Acute Coronary Syndrome in a Low to Intermediate-risk Patient with Chest Pain.

Ahmed Zaghloul, Corina Iorgoveanu, Kathir Balakumaran, Dinu V Balanescu, Teodora Donisan,

The optimal management of patients with chest pain relies on the prognostic information provided by noninvasive cardiovascular testing. Coronary computed tomography angiography (CCTA) is an increasingly utilized, highly accurate noninvasive test for diagnosing coronary artery disease. We illustrate an exceptional limitation of the prognostic information provided by CCTA. A 46-year-old ... Read more >>

Cureus (Cureus)
[2018, 10(5):e2649]

Cited: 1 time

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A Case of Brugada Pattern Associated with Adrenal Insufficiency.

Corina Iorgoveanu, Ahmed Zaghloul, Aakash Desai, Kathir Balakumaran, Muhammad Y Adeel,

Brugada syndrome (BrS) is an inherited channelopathy disease, caused by genetic changes in transmembrane ion channels. It has an increased risk of sudden cardiac death (SCD) in the absence of a structural heart disease. We report a case in which the presenting electrocardiogram (EKG) exhibited a type 1 Brugada-like pattern ... Read more >>

Cureus (Cureus)
[2018, 10(6):e2752]

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Unresponsive Intractable Chronic Headache With Sitagliptin.

Ahmed Zaghloul, Corina Iorgoveanu, Andrew Polio, Aakash Desai,

Sitagliptin is an anti-diabetic medication within the dipeptidyl peptidase 4 (DPP4) inhibitor class used as a single agent or in combination therapy. It is a well-studied and well-tolerated medication with commonly reported adverse events of upper respiratory tract infections, nasopharyngitis, headache, and gastrointestinal (GI) upset. Post-marketing reports have also identified associations ... Read more >>

Cureus (Cureus)
[2018, 10(4):e2537]

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Bilateral Earlobe Crease as a Marker of Premature Coronary Artery Disease.

Corina Iorgoveanu, Ahmed Zaghloul, Aakash Desai, Anand M Krishnan, Kathir Balakumaran,

Cardiovascular diseases, including heart disease and stroke, are the world's largest killers. More than 800,000 people die from cardiovascular disease each year in the United States (US). Heart disease is estimated to cost 200 billion US Dollars (USD) annually. Early identification of an inexpensive marker which allows for early intervention ... Read more >>

Cureus (Cureus)
[2018, 10(5):e2616]

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Lyme Meningoencephalitis Masquerading as Normal Pressure Hydrocephalus.

Aakash Desai, Gaurav Manek, Anand M Krishnan, Corina Iorgoveanu, Ahmed Zaghloul,

Lyme disease is a tick-borne illness caused primarily by the spirochete Borrelia burgdorferi. The disease is most prevalent in forested areas endemic for Ixodes tick, which transmits the spirochete. Here, we describe a case of Lyme meningoencephalitis masquerading as normal pressure hydrocephalus (NPH) which initially presented with urinary incontinence, gait ... Read more >>

Cureus (Cureus)
[2018, 10(4):e2417]

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Kikuchi-Fujimoto Disease in a Young African American Male.

Ahmed Zaghloul, Corina Iorgoveanu, Andrew Polio, Aakash Desai,

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is an extremely rare, self-limiting disorder which typically presents with fever and painful, unilateral cervical lymphadenopathy in previously healthy individuals. Here, we describe a case of KFD which initially presented with fever of unknown origin. Due to its non-specific symptoms and ... Read more >>

Cureus (Cureus)
[2018, 10(4):e2508]

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Case Report: A rare case of prosthetic valve infective endocarditis caused by Aerococcus urinae

Muhammad Adeel, Saman Tariq, Hisham Akthar, Ahmed Zaghloul, Corina Iorgoveanu, Carina Dehner,

Infective endocarditis (IE) is a serious and life-threatening cardiac condition, most commonly caused by staphylococci, Streptococcus viridans, and enterococci. However, in special settings, IE can be caused by rare organisms. Here we present a case of IE caused by Aerococcus urinae in a 75-year-old man with a bioprosthetic aortic valve.  ... Read more >>

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Case Report: A rare case of prosthetic valve infective endocarditis caused by Aerococcus urinae.

Muhammad Adeel, Saman Tariq, Hisham Akthar, Ahmed Zaghloul, Corina Iorgoveanu, Carina Dehner,

Infective endocarditis (IE) is a serious and life-threatening cardiac condition, most commonly caused by staphylococci, Streptococcus viridans, and enterococci. However, in special settings, IE can be caused by rare organisms. Here we present a case of IE caused by Aerococcus urinae in a 75-year-old man with a bioprosthetic aortic valve.  ... Read more >>

F1000Res (F1000Research)
[2017, 6:1998]

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New perspective in heart failure management: could myosin activators be the answer?

Stefan Andrei, Corina Iorgoveanu,

Heart failure is a worldwide leading cause of hospital admissions. There is a critical need for new methods of management in acute heart failure. The current drug panel available in the treatment of hemodinamically unstable patients is not only limited, but it is also associated with deleterious side effects. Discoveries ... Read more >>

Discoveries (Craiova) (Discoveries (Craiova, Romania))
[2014, 2(4):e33]

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