Full Text Journal Articles by
Author Conrad Tobert

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Comparison of Side Effects and Tolerability Between Intravesical Bacillus Calmette-Guerin, Reduced-Dose BCG, and Gemcitabine for Non-Muscle Invasive Bladder Cancer.

Joshua M Kuperus, Ross D Busman, Susan K Kuipers, Helen T Broekhuizen, Sabrina L Noyes, Christopher M Brede, Conrad M Tobert, Brian R Lane,

<h4>Objectives</h4>To compare patient-reported side effects and tolerability of full-dose Bacillus Calmette-Guérin (BCG), reduced-dose BCG, and gemcitabine one week after administration.<h4>Methods</h4>All patients from July 2019 to November 2020 receiving intravesical therapy (IVT) for non-muscle invasive bladder cancer (NMIBC) at our institution were surveyed before repeat instillation. Survey questions recorded IVT retention ... Read more >>

Urology (Urology)
[2021, :]

Cited: 0 times

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Knowledge and Attitudes Regarding Surgical Castration in Men Receiving Androgen Deprivation Therapy for Metastatic Prostate Cancer and Their Relationship to Health-Related Quality of Life.

Morgan E Schubbe, Paul T Gellhaus, Conrad M Tobert, Sarah L Mott, Rohan Garje, Bradley A Erickson,

<h4>Objective</h4>To determine the attitudes and education regarding surgical castration in men receiving androgen deprivation therapy (ADT) for metastatic prostate cancer (mCaP).<h4>Methods</h4>We identified 142 patients receiving ADT for mCaP at our institution without prior orchiectomy who were then sent 2 surveys via mail: (1) A questionnaire to assess knowledge and understanding ... Read more >>

Urology (Urology)
[2021, :]

Cited: 0 times

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Comparison of the Comprehensive Complication Index and Clavien-Dindo systems in predicting perioperative outcomes following radical nephroureterectomy.

Scott Geiger, Neil Kocher, Dan Illinsky, Evanguelos Xylinas, Peter Chang, Lauren Dewey, Andrew A Wagner, Firas Petros, Surena F Matin, Conrad Tobert, Chad Tracy, Pierre-Marie Patard, Mathieu Roumiguie, Leonardo Lima Monteiro, Wassim Kassouf, Jay D Raman,

<h4>Background</h4>Complications can occur following radical nephroureterectomy (RNU) in 20-40% of patients. The Comprehensive Complication Index (CCI) is an alternative grading system to the Clavien-Dindo (CD) grading system that aggregates all complications experienced by a patient on a continuous (as opposed to categorical) scale. We investigate whether the cumulative nature of ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2020, 9(4):1780-1785]

Cited: 1 time

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Enhancing Identification and Management of Hospitalized Patients Who Are Malnourished: A Pilot Evaluation of Electronic Quality Improvement Measures.

Kenneth G Nepple, Conrad M Tobert, Angel F Valladares, Kristi Mitchell, Martin Yadrick,

Malnutrition in hospitalized patients has long been recognized as a contributor to poor patient outcomes; malnutrition often leads to higher costs of care. Thus, it is important to improve the identification of patients who are at risk for malnutrition or already malnourished and to initiate treatment to optimize outcomes. The ... Read more >>

J Acad Nutr Diet (Journal of the Academy of Nutrition and Dietetics)
[2019, 119(9 Suppl 2):S32-S39]

Cited: 1 time

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Compliance With American Urological Association Guidelines for Nonmuscle Invasive Bladder Cancer Remains Poor: Assessing Factors Associated With Noncompliance and Survival in a Rural State.

Conrad M Tobert, Kenneth G Nepple, Bradley D McDowell, Mary E Charlton, Sarah L Mott, Thomas S Gruca, Laura Quast, Bradley A Erickson,

OBJECTIVE:To identify factors associated with nonmuscle invasive bladder cancer (NMIBC) American Urological Association (AUA) guideline compliance in a rural state, to evaluate compliance rates over time, and to assess the impact of patient and provider rurality on delivery of NMIBC care. METHODS:We identified 847 Iowans in Surveillance, Epidemiology, and End ... Read more >>

Urology (Urology)
[2019, 132:150-155]

Cited: 1 time

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Optimizing Nutrition Prior to Radical Cystectomy.

Anthony D Oberle, Jeremy M West, Conrad M Tobert, Gabriel L Conley, Kenneth G Nepple,

<h4>Purpose of review</h4>Malnutrition in a prevalent problem in patients undergoing radical cystectomy. Preoperative malnutrition has been shown to contribute to increased rates of postoperative complications. Given the significant morbidity and mortality of the procedure of radical cystectomy, there is potential for improvement in patient outcomes by nutritional intervention.<h4>Recent findings</h4>Prospective studies ... Read more >>

Curr Urol Rep (Current urology reports)
[2018, 19(12):99]

Cited: 3 times

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Comparison of RENAL, PADUA, CSA, and PAVP Nephrometry Scores in Predicting Functional Outcomes After Partial Nephrectomy.

Ruchir Gupta, Marco Tori, Stephen K Babitz, Conrad M Tobert, John G Anema, Sabrina L Noyes, Brian R Lane,

<h4>Objective</h4>To evaluate the accuracy of radius, exophytic/endophytic, nearness to collecting system/sinus, anterior/posterior, and location relative to polar lines (RENAL), preoperative aspects and dimensions used for anatomical classification (PADUA), contact surface area (CSA), and preoperative assessment of volume preservation (PAVP) nephrometry scores in predicting postoperative renal functional outcomes after partial nephrectomy ... Read more >>

Urology (Urology)
[2019, 124:160-167]

Cited: 1 time

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Growth spurts of small renal masses correlate with pathology.

Conrad M Tobert, Brian R Lane,

BJU Int (BJU international)
[2018, 121(5):678-679]

Cited: 0 times

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Malnutrition Diagnosis during Adult Inpatient Hospitalizations: Analysis of a Multi-Institutional Collaborative Database of Academic Medical Centers.

Conrad M Tobert, Sarah L Mott, Kenneth G Nepple,

<h4>Background</h4>Malnutrition is a significant problem for hospitalized patients. However, the true prevalence of reported malnutrition diagnosis in real-world clinical practice is largely unknown. Using a large collaborative multi-institutional database, the rate of malnutrition diagnosis was assessed and used to assess institutional variables associated with higher rates of malnutrition diagnosis.<h4>Objective</h4>The aim ... Read more >>

J Acad Nutr Diet (Journal of the Academy of Nutrition and Dietetics)
[2018, 118(1):125-131]

Cited: 14 times

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Chronic Kidney Disease Is More Common in Locally Advanced Renal Cell Carcinoma.

Sumi Dey, Zachary Hamilton, Sabrina L Noyes, Conrad M Tobert, Jacob Keeley, Ithaar H Derweesh, Brian R Lane,

<h4>Objective</h4>To retrospectively evaluate clinical predictors of chronic kidney disease (CKD) in renal cell carcinoma (RCC) patients to identify associations between patient- and tumor-specific factors with poorer renal function. CKD and RCC are interrelated, with 26%-44% of RCC patients having concomitant CKD at diagnosis.<h4>Patients and methods</h4>Institutional registries from Spectrum Health and ... Read more >>

Urology (Urology)
[2017, 105:101-107]

Cited: 3 times

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Emerging Impact of Malnutrition on Surgical Patients: Literature Review and Potential Implications for Cystectomy in Bladder Cancer.

Conrad M Tobert, Jill M Hamilton-Reeves, Lyse A Norian, Chermaine Hung, Nathan A Brooks, Jeff M Holzbeierlein, Tracy M Downs, Douglas P Robertson, Ruth Grossman, Kenneth G Nepple,

<h4>Purpose</h4>Malnutrition is emerging as a significant factor in patient outcomes. A contemporary review of malnutrition has not been performed for the urologist. We review the available literature and current standards of care for malnutrition screening, assessment and intervention, focusing on patients with bladder cancer treated with cystectomy.<h4>Materials and methods</h4>Our multidisciplinary ... Read more >>

J Urol (The Journal of urology)
[2017, 198(3):511-519]

Cited: 18 times

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Novel Management of Anastomotic Disruption and Persistent Hematuria Following Robotic Prostatectomy: Case Report and Review of the Literature.

Charles J Paul, Conrad M Tobert, Chad R Tracy,

Vesicourethral anastomosis leaks are not uncommon following radical prostatectomy. We present a case of a 59-year-old male who presented to our ED with hematuria, abdominal pain, and clot retention 17 days after a robotic-assisted laparoscopic prostatectomy. A 50% vesicourethral disruption was ultimately managed endoscopically and with hemostatic agents. At 9-month ... Read more >>

Urol Case Rep (Urology case reports)
[2017, 11:28-29]

Cited: 2 times

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Change in platelet count as a prognostic indicator for response to primary tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma.

Zachary Hamilton, Hak J Lee, Juan Jimenez, Brian R Lane, Song Wang, Alp T Beksac, Kyle Gillis, Amy Alagh, Conrad Tobert, James M Randall, Christopher J Kane, Frederick Millard, Steven C Campbell, Ithaar H Derweesh,

<h4>Objective</h4>To evaluate change in platelet count as an indicator of response to primary tyrosine kinase inhibitor (TKI) therapy for metastatic renal cell carcinoma (mRCC).<h4>Patients and methods</h4>We conducted a multicentre retrospective analysis of patients with mRCC undergoing primary TKI therapy from May 2005 to August 2014. Change in platelet count was ... Read more >>

BJU Int (BJU international)
[2016, 118(6):927-934]

Cited: 4 times

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Impact of Reduced Glomerular Filtration Rate and Proteinuria on Overall Survival of Patients with Renal Cancer.

Mouafak Tourojman, Samer Kirmiz, Bradley Boelkins, Sabrina L Noyes, Alan T Davis, Kelly O'Donnell, Conrad M Tobert, Brian R Lane,

<h4>Purpose</h4>Although it is commonly staged according to glomerular filtration rate, an international work group recommended classifying chronic kidney disease by cause, glomerular filtration rate and albuminuria. Data on nonsurgical patients with chronic kidney disease indicate proteinuria to be an independent predictor of renal function decrease and mortality. We evaluated whether ... Read more >>

J Urol (The Journal of urology)
[2016, 195(3):588-593]

Cited: 8 times

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Proteinuria is a Predictor of Renal Functional Decline in Patients with Kidney Cancer.

Kelly O'Donnell, Mouafak Tourojman, Conrad M Tobert, Samer W Kirmiz, Christopher B Riedinger, Sevag Demirjian, Brian R Lane,

<h4>Purpose</h4>Prior studies have shown that 26% to 34% of patients with suspected renal cancers have a glomerular filtration rate less than 60 ml/minute/1.73 m(2) but limited information exists regarding proteinuria. We investigated the extent of proteinuria in patients with renal tumors to determine the impact on the classification and progression ... Read more >>

J Urol (The Journal of urology)
[2016, 196(3):658-663]

Cited: 8 times

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Treatment of renal angiomyolipoma: pooled analysis of individual patient data.

Teele Kuusk, Fausto Biancari, Brian Lane, Conrad Tobert, Steven Campbell, Uri Rimon, Vito D'Andrea, Aare Mehik, Markku H Vaarala,

<h4>Background</h4>This study was performed to evaluate the impact of baseline characteristics and treatment methods on the outcome of sporadic renal angiomyolipoma (AML).<h4>Methods</h4>This was a pooled analysis of individual data of 441 patients with AML retrieved from 58 studies and 3 institutional series.<h4>Results</h4>Ninety-three patients underwent nephrectomy, 163 partial nephrectomy/enucleation, 128 embolisation, ... Read more >>

BMC Urol (BMC urology)
[2015, 15:123]

Cited: 24 times

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Multicenter Validation of Surgeon Assessment of Renal Preservation in Comparison to Measurement With 3D Image Analysis.

Conrad M Tobert, Toshio Takagi, Michael A Liss, Hak Lee, Ithaar H Derweesh, Steven C Campbell, Brian R Lane,

<h4>Objective</h4>To validate the findings of a prior single-surgeon series with a multi-institutional comparison of three-dimensional imaging of volume preservation (3DVP) and surgeon assessment of volume preservation (SAVP) as predictors of renal function after partial nephrectomy (PN). Baseline renal function and preservation of functioning renal parenchyma are the strongest predictors of ... Read more >>

Urology (Urology)
[2015, 86(3):534-538]

Cited: 6 times

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Modification of Technique for Suprapubic Catheter Placement After Robot-assisted Radical Prostatectomy Reduces Catheter-associated Complications.

Muhammad Zubair Afzal, Conrad M Tobert, Emi Bulica, Sabrina L Noyes, Brian R Lane,

<h4>Objective</h4>To compare the outcomes of patients undergoing robot-assisted radical prostatectomy (RARP) with urinary drainage using a modified technique for suprapubic catheter (SPC) placement with those undergoing a previously described technique for SPC placement and those with urethral catheter (UC) alone.<h4>Materials and methods</h4>We reviewed the records of 225 consecutive patients who ... Read more >>

Urology (Urology)
[2015, 86(2):401-406]

Cited: 3 times

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Critical appraisal of first-generation renal tumor complexity scoring systems: Creation of a second-generation model of tumor complexity.

Conrad M Tobert, Allen Shoemaker, Richard J Kahnoski, Brian R Lane,

<h4>Objective</h4>To investigate whether a combination of variables from each nephrometry system improves performance. There are 3 first-generation systems that quantify tumor complexity: R.E.N.A.L. nephrometry score (RNS), preoperative aspects and dimensions used for an anatomical (PADUA) classification (PC), and centrality index (CI). Although each has been subjected to validation and comparative ... Read more >>

Urol Oncol (Urologic oncology)
[2015, 33(4):167.e1-6]

Cited: 9 times

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Investigation of forces involved in closure of the renal remnant after simulated partial nephrectomy.

Donald M Endres, Robert W Bossemeyer, Conrad M Tobert, William H Baer, Brian R Lane,

<h4>Objective</h4>To investigate the potential biomechanical causes of the complications of partial nephrectomy (PN) in a preclinical model of sliding-clip renorrhaphy. PN is a reference standard for amenable small renal masses. One disadvantage of PN, however, is the risk of postoperative bleeding and/or urinary leak.<h4>Materials and methods</h4>Simulated tumor excision and reconstruction ... Read more >>

Urology (Urology)
[2014, 84(4):971-975]

Cited: 6 times

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Do we know (or just believe) that partial nephrectomy leads to better survival than radical nephrectomy for renal cancer?

Conrad M Tobert, Christopher B Riedinger, Brian R Lane,

<h4>Purpose</h4>Partial nephrectomy (PN) has become the gold standard for treating small renal masses amenable to such an approach. Surprisingly, the single randomized controlled trial of PN versus radical nephrectomy (RN) indicated an overall survival benefit for RN over PN. Recent studies have shed light on this discordance, and this review ... Read more >>

World J Urol (World journal of urology)
[2014, 32(3):573-579]

Cited: 18 times

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Surgeon assessment of renal preservation with partial nephrectomy provides information comparable to measurement of volume preservation with 3-dimensional image analysis.

Conrad M Tobert, Bradley Boelkins, Shannon Culver, Leena Mammen, Richard J Kahnoski, Brian R Lane,

<h4>Purpose</h4>The strongest predictors of renal function after partial nephrectomy are the preoperative glomerular filtration rate and the amount of preserved parenchyma. Measuring volume preservation by 3-dimensional imaging is accurate but time-consuming. Percent functional volume preservation was designed to replace surgeon assessment of volume preservation with a less labor intensive, objective ... Read more >>

J Urol (The Journal of urology)
[2014, 191(5):1218-1224]

Cited: 13 times

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Differential use of partial nephrectomy for intermediate and high complexity tumors may explain variability in reported utilization rates.

Brian R Lane, Shay Golan, Scott Eggener, Conrad M Tobert, Richard J Kahnoski, Alexander Kutikov, Marc Smaldone, Christopher M Whelan, Arieh Shalhav, Robert G Uzzo,

<h4>Purpose</h4>Partial nephrectomy has become a reference standard for tumors amenable to a kidney sparing approach but reported utilization rates vary widely. The R.E.N.A.L. (radius, exophytic/endophytic, nearness of tumor to collecting system or sinus, anterior/posterior, location relative to polar lines and hilar tumor touching main renal artery or vein) nephrometry score ... Read more >>

J Urol (The Journal of urology)
[2013, 189(6):2047-2053]

Cited: 20 times

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Growth kinetics and active surveillance for small renal masses.

Brian R Lane, Conrad M Tobert, Christopher B Riedinger,

<h4>Purpose of review</h4>Management options for small renal masses (SRMs) include excision, ablation, and active surveillance. Increasing interest in active surveillance, particularly for tumors of limited oncologic potential, in patients with other significant health concerns continues to rise, but precise protocols are still lacking.<h4>Recent findings</h4>A review of 18 retrospective series of ... Read more >>

Curr Opin Urol (Current opinion in urology)
[2012, 22(5):353-359]

Cited: 19 times

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Adjuvant and neoadjuvant therapy for renal cell carcinoma: a survey of the Society of Urologic Oncology.

Conrad M Tobert, Robert G Uzzo, Christopher G Wood, Brian R Lane,

<h4>Objective</h4>Several systemic agents have been approved for patients with advanced renal cell carcinoma (RCC) and others are in various stages of development. We surveyed members of the Society of Urologic Oncology (SUO) regarding the importance of adjuvant and neoadjuvant systemic therapy for RCC and their participation in such trials.<h4>Materials and ... Read more >>

Urol Oncol (Urologic oncology)
[2013, 31(7):1316-1320]

Cited: 11 times

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