Full Text Journal Articles by
Author Colin Carpenter

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Artificial Intelligence in Radiation Oncology Imaging.

Reid F Thompson, Gilmer Valdes, Clifton David Fuller, Colin M Carpenter, Olivier Morin, Sanjay Aneja, William D Lindsay, Hugo J W L Aerts, Barbara Agrimson, Curtiland Deville, Seth A Rosenthal, James B Yu, Charles R Thomas,

Int. J. Radiat. Oncol. Biol. Phys. (International journal of radiation oncology, biology, physics)
[2018, 102(4):1159-1161]

Cited: 2 times

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Artificial intelligence in radiation oncology: A specialty-wide disruptive transformation?

Reid F Thompson, Gilmer Valdes, Clifton D Fuller, Colin M Carpenter, Olivier Morin, Sanjay Aneja, William D Lindsay, Hugo J W L Aerts, Barbara Agrimson, Curtiland Deville, Seth A Rosenthal, James B Yu, Charles R Thomas,

Artificial intelligence (AI) is emerging as a technology with the power to transform established industries, and with applications from automated manufacturing to advertising and facial recognition to fully autonomous transportation. Advances in each of these domains have led some to call AI the "fourth" industrial revolution [1]. In healthcare, AI ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2018, 129(3):421-426]

Cited: 7 times

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The Future of Artificial Intelligence in Radiation Oncology.

Reid F Thompson, Gilmer Valdes, Clifton David Fuller, Colin M Carpenter, Olivier Morin, Sanjay Aneja, William D Lindsay, Hugo J W L Aerts, Barbara Agrimson, Curtiland Deville, Seth A Rosenthal, James B Yu, Charles R Thomas,

Int. J. Radiat. Oncol. Biol. Phys. (International journal of radiation oncology, biology, physics)
[2018, 102(2):247-248]

Cited: 1 time

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Spatial genetic structure in American black bears (Ursus americanus): female philopatry is variable and related to population history.

Thea V Kristensen, Emily E Puckett, Erin L Landguth, Jerrold L Belant, John T Hast, Colin Carpenter, Jaime L Sajecki, Jeff Beringer, Myron Means, John J Cox, Lori S Eggert, Don White, Kimberly G Smith,

Previously, American black bears (Ursus americanus) were thought to follow the pattern of female philopatry and male-biased dispersal. However, recent studies have identified deviations from this pattern. Such flexibility in dispersal patterns can allow individuals greater ability to acclimate to changing environments. We explored dispersal and spatial genetic relatedness patterns ... Read more >>

Heredity (Edinb) (Heredity)
[2018, 120(4):329-341]

Cited: 0 times

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Clinical decision support of radiotherapy treatment planning: A data-driven machine learning strategy for patient-specific dosimetric decision making.

Gilmer Valdes, Charles B Simone, Josephine Chen, Alexander Lin, Sue S Yom, Adam J Pattison, Colin M Carpenter, Timothy D Solberg,

Clinical decision support systems are a growing class of tools with the potential to impact healthcare. This study investigates the construction of a decision support system through which clinicians can efficiently identify which previously approved historical treatment plans are achievable for a new patient to aid in selection of therapy.Treatment ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2017, 125(3):392-397]

Cited: 11 times

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Flexible radioluminescence imaging for FDG-guided surgery.

Martin T King, Cesare H Jenkins, Conroy Sun, Colin M Carpenter, Xiaowei Ma, Kai Cheng, Quynh-Thu Le, John B Sunwoo, Zhen Cheng, Guillem Pratx, Lei Xing,

Flexible radioluminescence imaging (Flex-RLI) is an optical method for imaging 18F-fluorodeoxyglucose (FDG)-avid tumors. The authors hypothesize that a gadolinium oxysulfide: terbium (GOS:Tb) flexible scintillator, which loosely conforms to the body contour, can enhance tumor signal-to-background ratio (SBR) compared with RLI, which utilizes a flat scintillator. The purpose of this paper ... Read more >>

Med Phys (Medical physics)
[2016, 43(10):5298]

Cited: 2 times

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Image guided near-infrared spectroscopy of breast tissue in vivo using boundary element method.

Subhadra Srinivasan, Colin M Carpenter, Hamid R Ghadyani, Senate J Taka, Peter A Kaufman, Roberta M Diflorio-Alexander, Wendy A Wells, Brian W Pogue, Keith D Paulsen,

We demonstrate quantitative functional imaging using image-guided near-infrared spectroscopy (IG-NIRS) implemented with the boundary element method (BEM) for reconstructing 3-D optical property estimates in breast tissue in vivo. A multimodality MRI-NIR system was used to collect measurements of light reflectance from breast tissue. The BEM was used to model light ... Read more >>

J Biomed Opt (Journal of biomedical optics)
[2010, 15(6):061703]

Cited: 5 times

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MR water quantitative priors improves the accuracy of optical breast imaging.

Colin M Carpenter, Brian W Pogue, Shudong Jiang, Jia Wang, Brian A Hargreaves, Rebecca Rakow-Penner, Bruce L Daniel, Keith D Paulsen,

Magnetic resonance (MR) guided optical breast imaging is a promising modality to improve the specificity of breast imaging, because it provides high-resolution quantitative maps of total hemoglobin, oxygen saturation, water content, and optical scattering. These properties have been shown to distinguish malignant from benign lesions. However, the optical detection hardware ... Read more >>

IEEE Trans Med Imaging (IEEE transactions on medical imaging)
[2011, 30(1):159-168]

Cited: 4 times

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Inspired gas-induced vascular change in tumors with magnetic-resonance-guided near-infrared imaging: human breast pilot study.

Colin M Carpenter, Rebecca Rakow-Penner, Shudong Jiang, Bruce L Daniel, Brian W Pogue, Gary H Glover, Keith D Paulsen,

This study investigates differences in the response of breast tumor tissue versus healthy fibroglandular tissue to inspired gases. Cycles of carbogen and oxygen gas are administered while measuring the changes with magnetic-resonance-guided near-infrared imaging in a pilot study of breast cancers. For two patients, analyses are performed with cross-correlation techniques, ... Read more >>

J Biomed Opt (Journal of biomedical optics)
[2010, 15(3):036026]

Cited: 11 times

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Tomographic molecular imaging of x-ray-excitable nanoparticles.

Guillem Pratx, Colin M Carpenter, Conroy Sun, Ravi P Rao, Lei Xing,

X-ray luminescence computed tomography (XLCT) is proposed as a new dual molecular/anatomical imaging modality. XLCT is based on the selective excitation and optical detection of x-ray-excitable nanoparticles. As a proof of concept, we built a prototype XLCT system and imaged near-IR-emitting Gd(2)O(2)S:Eu phosphors in various phantoms. Imaging in an optically ... Read more >>

Opt Lett (Optics letters)
[2010, 35(20):3345-3347]

Cited: 45 times

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Evaluation of breast tumor response to neoadjuvant chemotherapy with tomographic diffuse optical spectroscopy: case studies of tumor region-of-interest changes.

Shudong Jiang, Brian W Pogue, Colin M Carpenter, Steven P Poplack, Wendy A Wells, Christine A Kogel, Jorge A Forero, Lori S Muffly, Gary N Schwartz, Keith D Paulsen, Peter A Kaufman,

To evaluate two methods of summarizing tomographic diffuse optical spectroscopic (DOS) data through region-of-interest (ROI) analysis to differentiate complete from incomplete responses in patients with locally advanced breast cancer undergoing neoadjuvant treatment and to estimate the standard deviations of these methods for power analysis of larger study designs in the ... Read more >>

Radiology (Radiology)
[2009, 252(2):551-560]

Cited: 64 times

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OPTIMIZATION OF 3-D IMAGE-GUIDED NEAR INFRARED SPECTROSCOPY USING BOUNDARY ELEMENT METHOD.

Subhadra Srinivasan, Colin Carpenter, Brian W Pogue, Keith D Paulsen,

Multimodality imaging systems combining optical techniques with MRI/CT provide high-resolution functional characterization of tissue by imaging molecular and vascular biomarkers. To optimize these hybrid systems for clinical use, faster and automatable algorithms are required for 3-D imaging. Towards this end, a boundary element model was used to incorporate tissue boundaries ... Read more >>

Proc IEEE Int Symp Biomed Imaging (Proceedings. IEEE International Symposium on Biomedical Imaging)
[2009, 2009:1075-1078]

Cited: 0 times

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Sensitivity of hemoglobin concentration on optical probe positioning in image-guided near infrared spectroscopy.

Subhadra Srinivasan, Colin Carpenter, Brian W Pogue,

Multi-modality image-guided near infrared spectroscopy provides volume-based quantification of total hemoglobin, oxygen saturation, water and scatter in various tissue types in-vivo. The accuracy of these parameters depends on the location of the imaging probe and its distance from the tumor. In a numerical study, we have performed simulation to analyze ... Read more >>

Conf Proc IEEE Eng Med Biol Soc (Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference)
[2009, 2009:1994-1996]

Cited: 0 times

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A boundary element approach for image-guided near-infrared absorption and scatter estimation.

Subhadra Srinivasan, Brian W Pogue, Colin Carpenter, Phaneendra K Yalavarthy, Keith Paulsen,

Multimodality NIR spectroscopy systems offer the possibility of region-based vascular and molecular characterization of tissue in vivo. However, computationally efficient 3D image reconstruction algorithms specific to these image-guided systems currently do not exist. Image reconstruction is often based on finite-element methods (FEMs), which require volume discretization. Here, a boundary element ... Read more >>

Med Phys (Medical physics)
[2007, 34(11):4545-4557]

Cited: 19 times

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Near infrared optical tomography using NIRFAST: Algorithm for numerical model and image reconstruction.

Hamid Dehghani, Matthew E Eames, Phaneendra K Yalavarthy, Scott C Davis, Subhadra Srinivasan, Colin M Carpenter, Brian W Pogue, Keith D Paulsen,

Diffuse optical tomography, also known as near infrared tomography, has been under investigation, for non-invasive functional imaging of tissue, specifically for the detection and characterization of breast cancer or other soft tissue lesions. Much work has been carried out for accurate modeling and image reconstruction from clinical data. NIRFAST, a ... Read more >>

Commun Numer Methods Eng (Communications in numerical methods in engineering)
[2008, 25(6):711-732]

Cited: 139 times

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Structural information within regularization matrices improves near infrared diffuse optical tomography.

Phaneendra K Yalavarthy, Brian W Pogue, Hamid Dehghani, Colin M Carpenter, Shudong Jiang, Keith D Paulsen,

Near-Infrared (NIR) tomographic image reconstruction is a non-linear, ill-posed and ill-conditioned problem, and so in this study, different ways of penalizing the objective function with structural information were investigated. A simple framework to incorporate structural priors is presented, using simple weight matrices that have either Laplacian or Helmholtz-type structures. Using ... Read more >>

Opt Express (Optics express)
[2007, 15(13):8043-8058]

Cited: 71 times

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Developments in quantitative oxygen-saturation imaging of breast tissue in vivo using multispectral near-infrared tomography.

Subhadra Srinivasan, Brian W Pogue, Colin Carpenter, Shudong Jiang, Wendy A Wells, Steven P Poplack, Peter A Kaufman, Keith D Paulsen,

Imaging of oxygen saturation provides a spatial map of the tissue metabolic activity and has potential in diagnosis and treatment monitoring of breast cancer. Oxygen-saturation imaging is possible through near-infrared (NIR) tomography, but has low signal-to-noise ratio (SNR). This can be augmented by using NIR tomography as an add-on to ... Read more >>

Antioxid. Redox Signal. (Antioxidants & redox signaling)
[2007, 9(8):1143-1156]

Cited: 15 times

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Image-guided optical spectroscopy provides molecular-specific information in vivo: MRI-guided spectroscopy of breast cancer hemoglobin, water, and scatterer size.

Colin M Carpenter, Brian W Pogue, Shudong Jiang, Hamid Dehghani, Xin Wang, Keith D Paulsen, Wendy A Wells, Jorge Forero, Christine Kogel, John B Weaver, Steven P Poplack, Peter A Kaufman,

A multimodality instrument that integrated optical or near-infrared spectroscopy into a magnetic resonance imaging (MRI) breast coil was used to perform a pilot study of image-guided spectroscopy on cancerous breast tissue. These results are believed to be the first multiwavelength spectroscopic images of breast cancer using MRI-guided constraints, and they ... Read more >>

Opt Lett (Optics letters)
[2007, 32(8):933-935]

Cited: 69 times

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