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Transarterial chemoembolization of unresectable systemic chemotherapy refractory liver metastases: a retrospective single-center analysis.

Yanqiao Ren, Lei Chen, Songjiang Huang, Chen Zhou, Jiacheng Liu, Qin Shi, Chongtu Yang, Renwang Chen, Chuansheng Zheng, Ping Han, Bin Xiong,

PURPOSE:The purpose of this study was to evaluate the therapeutic efficacy and safety of transarterial chemoembolization (TACE) in the treatment of patients with unresectable colorectal cancer liver metastases (CRCLM) who had failed systemic chemotherapy. In addition, the role of TACE in the treatment of CRCLM is also worth discussing. METHODS:This ... Read more >>

Abdom Radiol (NY) (Abdominal radiology (New York))
[2020, :]

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Correlation between Chest CT Findings and Clinical Features of 211 COVID-19 Suspected Patients in Wuhan, China.

Songlin Song, Feihong Wu, Yiming Liu, Hongwei Jiang, Fu Xiong, Xiaopeng Guo, Hongsen Zhang, Fan Yang, Chuansheng Zheng,

AbstractBackgroundChest CT has been widely used to assess the pulmonary involvement in COVID-19. We aimed to investigate the correlation between chest CT and clinical features in COVID-19 suspected patients with or without fever.MethodsWe retrospectively enrolled 211 COVID-19 suspected patients who underwent both chest CT and RT-PCR in Wuhan, China. The ... Read more >>

Open Forum Infect Dis (Open Forum Infectious Diseases)
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Spontaneous Pneumomediastinum: A Probable Unusual Complication of Coronavirus Disease 2019 (COVID-19) Pneumonia.

Jing Wang, Xiaoyun Su, Tianjing Zhang, Chuansheng Zheng,

Korean J Radiol (Korean journal of radiology)
[2020, 21(5):627-628]

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Prognostic Value of Baseline Clinical and HRCT Findings in 101 Patients with Severe COVID-19 in Wuhan, China

Yukun Cao, Xiaoyu Han, Jin Gu, Yumin Li, Jia Liu, Osamah Alwalid, Yue Cui, Xin Zhang, Chuansheng Zheng, Yanqing Fan, Hanping Wu, Heshui Shi,

Abstract Background It has been reported that patients with severe Coronavirus disease 2019 (COVID-19) had high mortality rate, but the information about prognostic factors for these patients is unknown. The aim of this study was to assess the prognostic value of baseline clinical and high resolution CT (HRCT) findings in ... Read more >>

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Epidemiological,clinical and radiological findings in medical staff with COVID-19 in Wuhan, China: a single-centered, retrospective cohort study

Jie Liu, Liu Ouyang, Pi Guo, Haisheng Wu, Peng Fu, Yuliang Chen, Dan Yang, Xiaoyu Han, Yukun Cao, Osamah Alwalid, Hanping Wu, Heshui Shi, Fan Yang, Yu Hu, Chuansheng Zheng,

Abstract Backgrounds In December 2019, a pneumonia associated with the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) emerged in Wuhan city, China. As of 20 Feb 2020, a total of 2,055 medical staff infected with SARS-Cov-2 in China had been reported. The predominant cause of the infection and the failure ... Read more >>

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Transarterial Chemoembolization Combined with Iodine 125 Seeds Versus Transarterial Chemoembolization Combined with Radiofrequency Ablation in the Treatment of Early- and Intermediate-stage Hepatocellular Carcinoma

chen lei, Xuefeng Kan, Tao Sun, Yanqiao Ren, Yanyan Cao, Liangliang Yan, Bin Liang, Bin Xiong, Chuansheng Zheng,

Abstract Background: Transarterial chemoembolization (TACE), radiofrequency ablation (RFA), and iodine 125 seeds implantation are options treatments for hepatocellular carcinoma (HCC). The aim of this study is to compare the efficacy of the combined treatment of TACE with iodine 125 seeds implantation (TACE-iodine 125) with TACE with RFA (TACE-RFA) in patients ... Read more >>

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Liver Injury in patients with COVID-19: Clinical Profiles, CT findings and their Correlation with the Severity

Ping Lei, Lan Zhang, Ping Han, Chuansheng Zheng, Qiaoxia Tong, Haitao Shang, Fan Yang, Yu Hu, Xin Li, Yuhu Song,

Abstract BACKGROUND & AIMS: Liver injury is found in some of patients with COVID-19. Liver injury of patients based on severity grading and abdominal radiological signs have not been reported until now. The aim of our study is to determine clinical profiles of the patients based on severity grading, describe ... Read more >>

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Comparisons of chest computed tomography patterns between survivors and non-survivors with Coronavirus Disease 2019 (COVID-19): a case-control study

Feng Pan, Chuansheng Zheng, Tianhe Ye, Lingli Li, Dehan Liu, Lin Li, Richard Hesketh, Lian Yang,

Abstract Objectives To compare the chest computed tomography (CT) findings between survivors and non-survivors with Coronavirus Disease 2019 (COVID-19). Materials and Methods Between 12 January 2020 to 20 February 2020, the records of 124 consecutive patients diagnosed with COVID-19 were retrospectively reviewed and divided into survivor (83/124) and non-survivor (41/124) ... Read more >>

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The Trends and Efficacy of Surgery in the Treatment of Hepatocellular Carcinoma

Lei Chen, Shi Chen, Tao Sun, Fan Yang, Chuansheng Zheng,

Abstract Background Surgery for the treatment of hepatocellular carcinoma (HCC) is limited. Recently, the possibility was advanced that surgical approach could be applied in HCC patients more widely. To address this issue, the trends in the use of surgery (including liver resection and ablation et, al) and liver resection ... Read more >>

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Radiological and clinical characteristics of 22 suspected COVID-19 patients with multiple negative RT-PCR testing

Wenjun Wu, Heshui Shi, Bo Liang, Feihong Wu, Dongqiao Xiang, Ziji Qin, Hongyan Zhou, Chuansheng Zheng, Lixia Wang,

Abstract This study aims to investigate radiological and clinical characteristics of suspected COVID-19 patients with negative RT-PCR testing. 22 suspected COVID-19 patients with 2-5 negative RT-PCR testing were enrolled. The most common symptoms at onset included fever (18[81.8%] patients), fatigue (16[72.7%]) and cough (12[54.5%]). 20(90.9%) patients were with normal or ... Read more >>

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Novel Coronavirus Pneumonia (COVID-19) Progression Course in 17 Discharged Patients: Comparison of Clinical and Thin-Section CT Features During Recovery.

Xiaoyu Han, Yukun Cao, Nanchuan Jiang, Yan Chen, Osamah Alwalid, Xin Zhang, Jin Gu, Meng Dai, Jie Liu, Wanyue Zhu, Chuansheng Zheng, Heshui Shi,

BACKGROUND:To retrospectively analyze the evolution of clinical features and thin-section CT imaging of novel coronavirus pneumonia (COVID-19) in 17 discharged patients. METHODS:Serial thin-section CT scans of 17 discharged patients with COVID-19 were obtained during recovery. Longitudinal changes of clinical parameters and CT pattern were documented in all patients during 4 ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Severe coronavirus disease 2019: CT changes based on prognosis

Bin Liang, Lingli Xie, Fan Yang, Joyman Makamure, Lijie Zhang, Ran Pang, Peng Du, Wenhui Fan, Chuansheng Zheng,

Abstract Purpose: To determine the characteristics of CT changes in patients with severe coronavirus disease 2019 (COVID-19) based on prognosis. Method: Serial CT scans in 47 patients with severe COVID-19 were reviewed. The patterns, distribution and CT score of lung abnormalities were assessed. Scans were classified according to duration in ... Read more >>

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Development and Evaluation of an AI System for COVID-19 Diagnosis

Cheng Jin, Weixiang Chen, Yukun Cao, Zhanwei Xu, Xin Zhang, Lei Deng, Chuansheng Zheng, Jie Zhou, Heshui Shi, Jianjiang Feng,

Early detection of COVID-19 based on chest CT will enable timely treatment of patients and help control the spread of the disease. With rapid spreading of COVID-19 in many countries, however, CT volumes of suspicious patients are increasing at a speed much faster than the availability of human experts. Here, ... Read more >>

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Clinical manifestations, CT features and outcome of 39 patients with COVID-19: retrospective case analysis

Haohao Lu, Chuansheng Zheng, Qiaoxia Tong, Jin Tian,

Abstract 1. BackgroundTo explore the manifestations and evolution of the pulmonary CT in COVID-19, and to analyze the causes and countermeasures of “Recurrent positive” in discharged patients.2. MethodsData of 39 patients with COVID-19 were collected. RT-PCR was positive at admission.From onset to discharge, pulmonary CT was performed regularly.During the treatment,Blood-RT,CRP ... Read more >>

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The Efficacy of Surgery in Advanced Hepatocellular Carcinoma: A Cohort Study

Lei Chen, Tao Sun, Shi Chen, Yanqiao Ren, Fan Yang, Chuansheng Zheng,

Abstract Background It is still controversial that whether hepatocellular carcinoma (HCC) patients with lymph node invasion should receive surgery treatment. This study aimed to evaluate the efficacy of surgery (liver resection and local tumor destruction treatments[l陈1] ) in HCC patients with regional lymph node metastasis. Methods The study utilized data ... Read more >>

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Use of Magnetic Resonance Neurography for Evaluating the Distribution and Patterns of Chronic Inflammatory Demyelinating Polyneuropathy.

Xiaoyun Su, Xiangquan Kong, Zuneng Lu, Min Zhou, Jing Wang, Xiaoming Liu, Xiangchuang Kong, Huiting Zhang, Chuansheng Zheng,

OBJECTIVE:To evaluate the distribution and characteristics of peripheral nerve abnormalities in chronic inflammatory demyelinating polyneuropathy (CIDP) using magnetic resonance neurography (MRN) and to examine the diagnostic efficiency. MATERIALS AND METHODS:Thirty-one CIDP patients and 21 controls underwent MR scans. Three-dimensional sampling perfections with application-optimized contrasts using different flip-angle evolutions and T1-/T2- ... Read more >>

Korean J Radiol (Korean journal of radiology)
[2020, 21(4):483-493]

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Exploration of interventional therapy strategy for portal vein occlusion: a case series study.

Jiacheng Liu, Chen Zhou, Qin Shi, Jinqiang Ma, Tianhe Ye, Chuansheng Zheng, Gansheng Feng, Bin Xiong,

OBJECTIVES:To explore the candidates, efficacy and safety of interventional therapies in the treatment of portal vein occlusion (PVO). METHODS:In our study, 13 patients diagnosed with PVO were included. Of all 13 patients, two received percutaneous portal vein recanalization (PVR), 10 received PVR and transjugular intrahepatic portosystemic shunt (PVR-TIPS), and one ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2020, 32(4):507-516]

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CT screening for early diagnosis of SARS-CoV-2 infection - Authors' reply.

Heshui Shi, Xiaoyu Han, Yukun Cao, Osamah Alwalid, Chuansheng Zheng,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2020, :]

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Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis.

Dehan Liu, Lin Li, Xin Wu, Dandan Zheng, Jiazheng Wang, Lian Yang, Chuansheng Zheng,

OBJECTIVE. The purpose of this study was to describe the clinical manifestations and CT features of coronavirus disease (COVID-19) pneumonia in 15 pregnant women and to provide some initial evidence that can be used for guiding treatment of pregnant women with COVID-19 pneumonia. MATERIALS AND METHODS. We reviewed the clinical ... Read more >>

AJR Am J Roentgenol (AJR. American journal of roentgenology)
[2020, :1-6]

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Deep Learning-based Detection for COVID-19 from Chest CT using Weak Label

Chuansheng Zheng, Xianbo Deng, Qing Fu, Qiang Zhou, Jiapei Feng, Hui Ma, Wenyu Liu, Xinggang Wang,

Accurate and rapid diagnosis of COVID-19 suspected cases plays a crucial role in timely quarantine and medical treatment. Developing a deep learning-based model for automatic COVID-19 detection on chest CT is helpful to counter the outbreak of SARS-CoV-2. A weakly-supervised deep learning-based software system was developed using 3D CT volumes ... Read more >>

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Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study.

Heshui Shi, Xiaoyu Han, Nanchuan Jiang, Yukun Cao, Osamah Alwalid, Jin Gu, Yanqing Fan, Chuansheng Zheng,

BACKGROUND:A cluster of patients with coronavirus disease 2019 (COVID-19) pneumonia caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were successively reported in Wuhan, China. We aimed to describe the CT findings across different timepoints throughout the disease course. METHODS:Patients with COVID-19 pneumonia (confirmed by next-generation sequencing or ... Read more >>

Lancet Infect Dis (The Lancet. Infectious diseases)
[2020, 20(4):425-434]

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Evolution of CT Manifestations in a Patient Recovered from 2019 Novel Coronavirus (2019-nCoV) Pneumonia in Wuhan, China.

Heshui Shi, Xiaoyu Han, Chuansheng Zheng,

Radiology (Radiology)
[2020, 295(1):20]

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Time Course of Lung Changes at Chest CT during Recovery from Coronavirus Disease 2019 (COVID-19).

Feng Pan, Tianhe Ye, Peng Sun, Shan Gui, Bo Liang, Lingli Li, Dandan Zheng, Jiazheng Wang, Richard L Hesketh, Lian Yang, Chuansheng Zheng,

Background Chest CT is used to assess the severity of lung involvement in coronavirus disease 2019 (COVID-19). Purpose To determine the changes in chest CT findings associated with COVID-19 from initial diagnosis until patient recovery. Materials and Methods This retrospective review included patients with real-time polymerase chain reaction-confirmed COVID-19 who ... Read more >>

Radiology (Radiology)
[2020, 295(3):715-721]

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Transarterial chemoembolization combined with apatinib for treatment of advanced hepatocellular carcinoma: analysis of survival and prognostic factors

Ziyi Liu, Xuefeng Kan, Lijie Zhang, Joyman Makamure, Qing Li, Dan Zhao, Guofeng Zhou, Gansheng Feng, Chuansheng Zheng, Bin Liang,

Abstract Backgroud: To evaluate the overall survival (OS) after transarterial chemoembolization (TACE) combined with apatinib in patients with advanced hepatocellular carcinoma (HCC), and to identify the factors affecting patient survival. Methods: Fifty-one patients with HCC who received TACE combined with apatinib in our hospital from June 2015 to May 2017 ... Read more >>

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Platelet-to-lymphocyte ratio predicts therapy outcomes of transarterial chemoembolization plus apatinib in the treatment of advanced hepatocellular carcinoma.

Lei Chen, Zunqian Ke, Fu Xiong, Xuefeng Kan, Yanqiao Ren, Yanyan Cao, Tao Sun, Liangliang Yan, Guofeng Zhou, Chuansheng Zheng,

To evaluate the predictive value of preoperative biochemical marker [platelet-to-lymphocyte ratio (PLR)] in patients with advanced hepatocellular cancer receiving transarterial chemoembolization (TACE) plus targeted molecular therapy (apatinib) treatment. Clinical records of 134 patients receiving the treatment of TACE + apatinib (TACE-A) and the treatment of TACE alone were compared in ... Read more >>

Anticancer Drugs (Anti-cancer drugs)
[2020, :]

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