Full Text Journal Articles by
Author Christopher Santas

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Cost-effectiveness of KRAS testing in metastatic colorectal cancer patients in the United States and Germany.

Arthi Vijayaraghavan, Molly B Efrusy, Burkhard Göke, Thomas Kirchner, Christopher C Santas, Richard M Goldberg,

The objective of this study was to determine the cost-effectiveness of testing for KRAS mutations before administering EGFR inhibitors such as cetuximab and panitumumab for patients with advanced metastatic colorectal cancer (mCRC) in the United States and Germany. We developed a lifetime Markov model of costs and survival associated with ... Read more >>

Int J Cancer (International journal of cancer)
[2012, 131(2):438-445]

Cited: 44 times

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Cost-effectiveness of high-risk human papillomavirus testing for cervical cancer screening in Québec, Canada.

Arthi Vijayaraghavan, Molly B Efrusy, Marie-Hélêne Mayrand, Christopher C Santas, Patricia Goggin,

<h4>Objectives</h4>Human papillomavirus (HPV) testing is not widely used for triage of equivocal Pap smears or primary screening in Québec, Canada. Our objective was to evaluate the cost-effectiveness of cervical cancer screening strategies utilizing HPV testing.<h4>Methods</h4>We used a lifetime Markov model to estimate costs, quality of life, and survival associated with ... Read more >>

Can J Public Health (Canadian journal of public health = Revue canadienne de sante publique)
[2010, 101(3):220-225]

Cited: 20 times

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Cost-effectiveness of using human papillomavirus 16/18 genotype triage in cervical cancer screening.

Arthi Vijayaraghavan, Molly B Efrusy, Karyn A Goodman, Christopher C Santas, Warner K Huh,

<h4>Objective</h4>Testing for human papillomavirus (HPV) 16 and 18 genotypes, which are known to cause approximately 65-70% of invasive cervical cancer cases, may allow clinicians to identify women at highest risk for underlying cervical intraepithelial neoplasia missed by Pap cytology. Our objective was to determine the cost-effectiveness of adding HPV-16 and ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2010, 119(2):237-242]

Cited: 10 times

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Cost effectiveness of high-risk HPV DNA testing for cervical cancer screening in South Africa.

Arthi Vijayaraghavan, Molly Efrusy, Gerhard Lindeque, Greta Dreyer, Christopher Santas,

<h4>Objective</h4>To determine the cost effectiveness of several cervical cancer screening strategies utilizing HPV testing in South Africa.<h4>Methods</h4>We developed a lifetime Markov model of the costs, quality of life, and survival associated with screening and treating cervical cancer and its precursors. Screening strategies evaluated included: 1) conventional cytology, 2) cytology followed ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2009, 112(2):377-383]

Cited: 21 times

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An economic analysis of human papillomavirus triage for the management of women with atypical and abnormal Pap smear results in Germany.

Sara K Sheriff, K Ulrich Petry, Hans Ikenberg, Geoffrey Crouse, Peter D Mazonson, Christopher C Santas,

We developed decision-analytic models to determine the cost effectiveness of incorporating human papillomavirus (HPV) testing into the management of atypical and abnormal Pap smear results in Germany. The models compare three management strategies: (1) repeat Pap smear, (2) triage with HPV DNA testing, or (3) immediate treatment. The primary outcome ... Read more >>

Eur J Health Econ (The European journal of health economics : HEPAC : health economics in prevention and care)
[2007, 8(2):153-160]

Cited: 3 times

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Cost-effectiveness of alternative strategies for initiating and monitoring highly active antiretroviral therapy in the developing world.

Arthi Vijayaraghavan, Molly Bates Efrusy, Peter D Mazonson, Osman Ebrahim, Ian M Sanne, Christopher C Santas,

<h4>Objective</h4>Determine the cost-effectiveness of initiating and monitoring highly active antiretroviral therapy (HAART) in developing countries according to developing world versus developed world guidelines.<h4>Design</h4>Lifetime Markov model incorporating costs, quality of life, survival, and transmission to sexual contacts.<h4>Methods</h4>We evaluated treating patients with HIV in South Africa according to World Health Organization (WHO) ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2007, 46(1):91-100]

Cited: 36 times

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