Full Text Journal Articles by
Author Christopher K Fairley

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Brief Report: Changes in PrEP Use, Sexual Practice, and Use of Face Mask During Sex Among MSM During the Second Wave of COVID-19 in Melbourne, Australia.

Eric P F Chow, Jane S Hocking, Jason J Ong, Tiffany R Phillips, Tina Schmidt, Andrew Buchanan, Elena Rodriguez, Kate Maddaford, Christopher K Fairley,

<h4>Background</h4>A second wave of COVID-19 began in late June in Victoria, Australia. Stage 3 then Stage 4 restrictions were introduced in July-August. This study aimed to compare the use of pre-exposure prophylaxis (PrEP) and sexual practices among men who have sex with men taking PrEP between May-June (post-first lockdown) and ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):153-156]

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Brief Report: Group Sex Among Men Who Have Sex With Men in the Era of PrEP: A Cross-Sectional Study.

Tiffany R Phillips, Christopher K Fairley, Catriona S Bradshaw, Jane S Hocking, Edmond P H Choi, Jason J Ong, Marjan Tabesh, Kate Maddaford, Eric P F Chow,

<h4>Background</h4>Group sex has been commonly reported among gay and bisexual men who have sex with men (GBMSM); however, there are limited studies on the factors associated with participating in group sex.<h4>Setting</h4>A cross-sectional study among GBMSM attending a sexual health clinic in Melbourne, Australia.<h4>Methods</h4>Univariable and multivariable logistic regression were performed to ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):e23-e27]

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HIV, Sexually Transmitted Infections and Sexual Practices Among Male Sex Workers Attending a Sexual Health Clinic in Melbourne, Australia: 2010 to 2018.

Evelyn M Turek, Christopher K Fairley, Marjan Tabesh, Tiffany R Phillips, Catriona S Bradshaw, Elena Rodriguez, Eric P F Chow,

<h4>Background</h4>There are limited data on HIV/sexually transmitted infection (STI) positivity and sexual practices among male sex workers (MSWs) both globally and particularly in Australia. This study aimed to explore demographic characteristics, sexual practices, and HIV/STI positivity among MSWs attending a sexual health clinic in Melbourne.<h4>Methods</h4>We analyzed computerized medical records of ... Read more >>

Sex Transm Dis (Sexually transmitted diseases)
[2021, 48(2):103-108]

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Are Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum associated with specific genital symptoms and clinical signs in non-pregnant women?

Erica L Plummer, Lenka A Vodstrcil, Kaveesha Bodiyabadu, Gerald L Murray, Michelle Doyle, Rosie L Latimer, Christopher K Fairley, Matthew Payne, Eric P F Chow, Suzanne M Garland, Catriona S Bradshaw,

<h4>Background</h4>There is limited evidence supporting an association between Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum and symptoms or disease in non-pregnant women. However, testing and reporting of these organisms frequently occurs, in-part due to their inclusion in multiplex-PCR assays for sexually transmitted infection (STI) detection. We investigated if M. hominis, ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, :]

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Comparison of the patterns of chlamydia and gonorrhoea at the oropharynx, anorectum and urethra among men who have sex with men.

Marjan Tabesh, Christopher K Fairley, Jane S Hocking, Deborah A Williamson, Lei Zhang, Xianglong Xu, Catriona S Bradshaw, Marcus Y Chen, Eric Pf Chow,

<h4>Objective</h4>Chlamydia and gonorrhoea are common sexually transmitted infections that infect the oropharynx, anorectum and urethra in men who have sex with men (MSM). This study aimed to examine the pattern of infection at more than one site (multisite) for chlamydia and gonorrhoea among MSM.<h4>Methods</h4>This was a retrospective study of MSM ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2021, :]

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Associations between oral sex practices and frequent mouthwash use in heterosexuals: a cross-sectional survey in Melbourne, Australia.

Tiffany R Phillips, Christopher K Fairley, Catriona S Bradshaw, Marjan Tabesh, Kate Maddaford, Jane S Hocking, Eric Pf Chow,

<h4>Objective</h4>This study aimed to determine the frequency of mouthwash use and its association to oral sex practice in heterosexuals.<h4>Design</h4>A cross-sectional study.<h4>Setting</h4>Data obtained from a sexual health clinic in Victoria, Australia, between March 2019 and April 2019.<h4>Participants</h4>Heterosexual men and women attending the sexual health clinic answered a survey using computer-assisted self-interview.<h4>Primary ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041782]

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HIV testing and diagnoses during the COVID-19 pandemic in Melbourne, Australia.

Eric P F Chow, Jason J Ong, Ian Denham, Christopher K Fairley,

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2020, Publish Ahead of Print:]

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Group sex events among female sex workers in Melbourne, Australia.

Evelyn M Turek, Christopher K Fairley, Marjan Tabesh, Tiffany R Phillips, Eric P F Chow,

Background Group sex is associated with increased risk of HIV and sexually transmissible infections (STIs), but there is limited data on group sex among female sex workers (FSW). Understanding current group sex practices among FSW may assist with understanding and addressing the rise in STIs observed among Australian FSW in ... Read more >>

Sex Health (Sexual health)
[2020, 17(6):534-537]

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Validation of a clinical prediction rule to predict asymptomatic chlamydia and gonorrhoea infections among internet-based testers.

Aidan Ablona, Titilola Falasinnu, Michael Irvine, Claudia Estcourt, Paul Flowers, Michelle Murti, Oralia Gómez-Ramírez, Christopher K Fairley, Sharmistha Mishra, Ann Burchell, Troy Grennan, Mark Gilbert,

<h4>Background</h4>Clinical prediction rules (CPRs) can be used in STI testing environments to prioritize individuals at highest risk of infection and optimize resource allocation. We previously derived a CPR to predict asymptomatic chlamydia and/or gonorrhea (CT/NG) infection among women and heterosexual men at in-person STI clinics based on five predictors. Population ... Read more >>

Sex Transm Dis (Sexually transmitted diseases)
[2020, :]

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Effect of age on the association between recreational drug use and sexual risk behaviour: a cross-sectional observational analysis.

Arthur Wong, Garrett P Prestage, I Mary Poynten, Fengyi Jin, Richard J Hillman, Carmella Law, Christopher K Fairley, Suzanne M Garland, Andrew E Grulich, David J Templeton,

Recreational drug use (RDU) among gay and bisexual men (GBM) is associated with higher-risk sexual behaviours, however this has not been well defined among older GBM. We investigated the association between RDU and sexual behaviours among older GBM in Sydney, Australia. 617 GBM aged 35-79 years self-reported their RDU in ... Read more >>

Sex Health (Sexual health)
[2020, 17(6):538-542]

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Modeling the epidemiological impact and cost-effectiveness of a combined schoolgirl HPV vaccination and cervical cancer screening program among Chinese women.

Xiaomeng Ma, Katherine Harripersaud, Kumi Smith, Christopher K Fairley, Huachun Zou, Zhuoru Zou, Yueyun Wang, Guihua Zhuang, Lei Zhang,

Human papillomavirus (HPV) infection is common in women and also the main cause of cervical cancer. Based on a dynamic compartmental model, we aimed to evaluate the population impact and cost-effectiveness of strategies that combined cervical cancer screening and HPV schoolgirl vaccination for Chinese women. The effectiveness of interventions was ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, :1-10]

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HIV, immune dysfunction and the natural history of anal high-risk human papillomavirus infection in gay and bisexual men.

I Mary Poynten, Fengyi Jin, Suzanne M Garland, Richard J Hillman, Monica Molano, Jennifer M Roberts, David J Templeton, Samuel Phillips, Carmella Law, Christopher K Fairley, Annabelle Farnsworth, Andrew E Grulich,

<h4>Objectives</h4>Incidence of anal cancer is highest in gay and bisexual men (GBM). A better understanding of the natural history of anal high-risk human papillomavirus (HRHPV) infection is needed for anal cancer prevention.<h4>Methods</h4>The Study of the Prevention of Anal Cancer was a 3-year study of Australian GBM, aged 35 years or ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2020, :]

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The Impact of Markers of HIV Infection on Change in Liver Stiffness in People With HIV and Hepatitis C Virus Co-infection After Treatment and Cure of Hepatitis C.

Daniela K van Santen, Paul A Agius, Joseph Sasadeusz, Christopher K Fairley, William Sievert, Edward Gane, David Iser, Mark O'Reilly, Nicholas A Medland, Richard Moore, Margaret E Hellard, Jennifer F Hoy, Joseph S Doyle, ,

<h4>Background</h4>Markers of HIV disease severity are associated with increased liver fibrosis in HIV/Hepatitis C virus (HCV) co-infected individuals. HCV treatment may reverse liver fibrosis, but evidence among HIV/HCV-co-infected populations and the impact of HIV parameters on fibrosis regression is limited. We aimed to assess the influence of surrogate markers of ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2020, 85(5):e81-e89]

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Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study.

Eric P F Chow, Lenka A Vodstrcil, Deborah A Williamson, Kate Maddaford, Jane S Hocking, Melinda Ashcroft, Vesna De Petra, Catriona S Bradshaw, Christopher K Fairley,

<h4>Objectives</h4>This prospective cohort study aimed to determine the natural history and incidence of oropharyngeal gonorrhoea and chlamydia among a cohort of men who have sex with men (MSM) over a 12-week period, and to examine risk factors associated with incident oropharyngeal infections.<h4>Methods</h4>MSM either aged ≥18 years and had a diagnosis ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2020, :]

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Pre-exposure Prophylaxis for HIV - an opportunity for the global control of sexually transmitted infections.

Megan J Ung, Christopher K Fairley, Sarah J Martin, Jason J Ong,

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2020, :]

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Modelling the contribution that different sexual practices involving the oropharynx and saliva have on Neisseria gonorrhoeae infections at multiple anatomical sites in men who have sex with men.

Xianglong Xu, Eric P F Chow, Jason J Ong, Christian J P A Hoebe, Deborah Williamson, Mingwang Shen, Fabian Yuh Shiong Kong, Jane S Hocking, Christopher K Fairley, Lei Zhang,

<h4>Background</h4>The spectrum of sexual practices that transmit <i>Neisseria gonorrhoeae</i> in men who have sex with men (MSM) is controversial. No studies have modelled potential <i>Neisseria gonorrhoeae</i> transmission when one sexual practice follows another in the same sexual encounter ('sequential sexual practices'). Our aim was to test what sequential practices were ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2020, :]

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"Moving from one environment to another, it doesn't automatically change everything". Exploring the transnational experience of Asian-born gay and bisexual men who have sex with men newly arrived in Australia.

Tiffany R Phillips, Nicholas Medland, Eric P F Chow, Kate Maddaford, Rebecca Wigan, Christopher K Fairley, Jason J Ong, Jade E Bilardi,

Asian-born gay, bisexual and other men who have sex with men (gbMSM) who are newly arrived in Australia are at a higher risk of acquiring HIV than Australian-born gbMSM. We used a social constructionist framework to explore HIV knowledge and prevention strategies used by newly-arrived Asian-born gbMSM. Twenty four Asian-born ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242788]

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Chlamydia trachomatis transmission between the oropharynx, urethra and anorectum in men who have sex with men: a mathematical model.

Xianglong Xu, Eric P F Chow, Jason J Ong, Christian J P A Hoebe, Zhuoru Zou, Jane S Hocking, Christopher K Fairley, Lei Zhang,

<h4>Background</h4>It has been presumed that Chlamydia trachomatis is transmitted between men only through anal or oral sex, but no mathematical models have tested this presumption.<h4>Methods</h4>To test this presumption, we created 20 compartmental mathematical models of different sexual practices that included both oral and anal sex and calibrated these models to ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):326]

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Predicting the diagnosis of HIV and sexually transmitted infections among men who have sex with men using machine learning approaches.

Yining Bao, Nicholas A Medland, Christopher K Fairley, Jinrong Wu, Xianwen Shang, Eric P F Chow, Xianglong Xu, Zongyuan Ge, Xun Zhuang, Lei Zhang,

<h4>Objectives</h4>We aimed to develop machine learning models and evaluate their performance in predicting HIV and sexually transmitted infections (STIs) diagnosis based on a cohort of Australian men who have sex with men (MSM).<h4>Methods</h4>We collected clinical records of 21,273 Australian MSM during 2011-2017. We compared accuracies for predicting HIV and STIs ... Read more >>

J Infect (The Journal of infection)
[2021, 82(1):48-59]

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Treating male partners of women with bacterial vaginosis (StepUp): a protocol for a randomised controlled trial to assess the clinical effectiveness of male partner treatment for reducing the risk of BV recurrence.

Lenka A Vodstrcil, Erica L Plummer, Michelle Doyle, Christopher K Fairley, Colette McGuiness, Deborah Bateson, Jane S Hocking, Matthew G Law, Kathy Petoumenos, Basil Donovan, Eric P F Chow, Catriona S Bradshaw, ,

<h4>Background</h4>Bacterial vaginosis (BV) is estimated to affect 1 in 3 women globally and is associated with obstetric and gynaecological sequelae. Current recommended therapies have good short-term efficacy but 1 in 2 women experience BV recurrence within 6 months of treatment. Evidence of male carriage of BV-organisms suggests that male partners may ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2020, 20(1):834]

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An open-label, parallel-group, randomised controlled trial of antiseptic mouthwash versus antibiotics for oropharyngeal gonorrhoea treatment (OMEGA2).

Eric P F Chow, Kate Maddaford, Jane S Hocking, Catriona S Bradshaw, Rebecca Wigan, Marcus Y Chen, Benjamin P Howden, Deborah A Williamson, Christopher K Fairley,

New treatments for oropharyngeal gonorrhoea are required to address rising antimicrobial resistance. We aimed to examine the efficacy of a 14-day course of mouthwash twice daily compared to standard treatment (antibiotic) for the treatment of oropharyngeal gonorrhoea. The OMEGA2 trial was a parallel-group and open-labelled randomised controlled trial among men ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):19386]

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Treatment efficacy for pharyngeal Neisseria gonorrhoeae: a systematic review and meta-analysis of randomized controlled trials.

Fabian Y S Kong, Christina L Hatzis, Andrew Lau, Deborah A Williamson, Eric P F Chow, Christopher K Fairley, Jane S Hocking,

<h4>Background</h4>Rising gonorrhoea rates require highly effective treatments to reduce transmission and prevent development of antimicrobial resistance. Currently the most effective treatments for pharyngeal gonorrhoea remain unclear. This review aimed to estimate treatment efficacy for pharyngeal gonorrhoea.<h4>Methods</h4>Online bibliographic databases were searched for the period 1 January 2000 to 17 September 2019 ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2020, 75(11):3109-3119]

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Characteristics Analysis and Implications on the COVID-19 Reopening of Victoria, Australia.

Lei Zhang, Yusha Tao, Guihua Zhuang, Christopher K Fairley,

Innovation (N Y) (Innovation (New York, N.Y.))
[2020, 1(3):100049]

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Domestic HPV vaccine price and economic returns for cervical cancer prevention in China: a cost-effectiveness analysis.

Zhuoru Zou, Christopher K Fairley, Jason J Ong, Jane Hocking, Karen Canfell, Xiaomeng Ma, Eric P F Chow, Xianglong Xu, Lei Zhang, Guihua Zhuang,

<h4>Background</h4>Coinciding with the release of the first Chinese domestic human papillomavirus (HPV) vaccine Cecolin in 2019, and the substantial advancements in cervical cancer screening technology, we aimed to evaluate the cost-effectiveness of the combined strategies of cervical cancer screening programmes and universal vaccination of girls (aged 9-14 years) with Cecolin ... Read more >>

Lancet Glob Health (The Lancet. Global health)
[2020, 8(10):e1335-e1344]

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Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia.

Mario Martín-Sánchez, Christopher K Fairley, Jason J Ong, Kate Maddaford, Marcus Y Chen, Deborah A Williamson, Catriona S Bradshaw, Eric P F Chow,

Gonorrhoea cases in women have been rising in Australia in the 2010s but the cause of the increase is not well understood. This cross-sectional study aimed to describe the characteristics of genital gonorrhoea infection in women attending the Melbourne Sexual Health Centre, Australia. Gonorrhoea cases were diagnosed by nucleic acid ... Read more >>

Epidemiol Infect (Epidemiology and infection)
[2020, 148:e240]

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