Full Text Journal Articles by
Author Christopher Alexander

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Dual regulation of the actin cytoskeleton by CARMIL-GAP.

Goeh Jung, Miao Pan, Christopher J Alexander, Tian Jin, John A Hammer,

Capping protein Arp2/3 myosin I linker (CARMIL) proteins are multi-domain scaffold proteins that regulate actin dynamics by regulating the activity of capping protein (CP). Here, we characterize CARMIL-GAP (GAP for GTPase-activating protein), a Dictyostelium CARMIL isoform that contains a ∼130 residue insert that, by homology, confers GTPase-activating properties for Rho-related ... Read more >>

J Cell Sci (Journal of cell science)
[2022, 135(12):jcs258704]

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A Population-Based Study of Patients with Sleep-Wake Disorders Undergoing Elective Instrumented Spinal Surgery.

Kathryn N Becker, Connor S Gifford, Hanan Qaqish, Christopher Alexander, Gang Ren, Andrew Caras, William K Miller, Jason L Schroeder,

<h4>Background</h4>Sleep-wake disorders (SWDs) are associated with multiple systemic pathologies; however, the clinical risk that such disorders carry for spinal surgery patients is not well understood. In the present population-based study, we comprehensively evaluated the significance of sleep-related risk factors on instrumented spinal surgery outcomes.<h4>Methods</h4>National Inpatient Sample data for the hospitalization ... Read more >>

World Neurosurg (World neurosurgery)
[2022, 160:e335-e343]

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