Full Text Journal Articles by
Author Christoph Biehl

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Mortality, Risk Factors and Risk Assessment after Periprosthetic Femoral Fractures-A Retrospective Cohort Study.

Thaqif El Khassawna, Gero Knapp, Nadja Scheibler, Deeksha Malhan, Nike Walter, Christoph Biehl, Volker Alt, Christian Heiss, Markus Rupp,

Periprosthetic femoral fracture (PFF) is a devastating complication. Here, the authors aimed to determine the influence of the timing of surgery as a risk factor for mortality and poor postoperative outcome in patients suffering from PFF. A retrospective descriptive analysis of patients treated for PFF between January 2010 and March ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(19):]

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Ultrasound-accelerated thrombolysis in high-risk perioperative pulmonary embolism: two case reports and review of literature.

Götz Schmidt, Fabian Edinger, Christian Koch, Matthias Wolff, Christoph Biehl, Rüdiger Hörbelt, Michael Sander,

Treatment of high-risk pulmonary embolism (PE) in perioperative patients remains challenging. Systemic thrombolysis is associated with a high risk of major bleedings and intracranial haemorrhage. High mortality rates are reported for open pulmonary embolectomy. Therefore, postoperative surgical patients may benefit substantially from catheter-directed ultrasound-accelerated thrombolysis (USAT). We report two cases ... Read more >>

Perioper Med (Lond) (Perioperative medicine (London, England))
[2021, 10(1):35]

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Resonance vibration interventions in the femur: Experimental-numerical modelling approaches.

Alexandre Presas, David Valentin, Joseph Deering, Marian Kampschulte, Bosco Yu, Kathryn Grandfield, Elisa Mele, Christoph Biehl, Gabriele A Krombach, Christian Heiss, Wolfram A Bosbach,

<h4>Motive</h4>External vibration excitation might be key to many novel non-surgical interventions for pathologies in the musculoskeletal system and in other parts of the human organism. Lack of understanding about vibration patterns, their controllability, and reproducibility are three limitations of ongoing research. This study establishes a bovine vibration model and animal ... Read more >>

J Mech Behav Biomed Mater (Journal of the mechanical behavior of biomedical materials)
[2021, 124:104850]

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Long-Term Results of the Modular Physiological Wrist Prosthesis (MPW®) in Patients with Inflammatory Diseases.

Christoph Biehl, Martin Stoll, Martin Heinrich, Lotta Biehl, Jochen Jung, Christian Heiss, Gabor Szalay,

The wrist is among the predilection sites of over 90% of cases of rheumatoid arthritis (RA). In advanced cases, total wrist arthroplasty (TWA) is an alternative to arthrodesis. The aim of this study is to present the long-term results of the modular physiological wrist prosthesis (MPW<sup>®</sup>) and to match them ... Read more >>

Life (Basel) (Life (Basel, Switzerland))
[2021, 11(4):]

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Titel Treatment of Hand and Wrist Fractures with the Stryker Hand Plating System

Christoph Biehl, Sabine Stötzel, Lydia Schock, Gabor Szalay, Christian Heiss,

<h4>Background: </h4> 10% of all fractures occur in the fingers and metacarpal region. Early mobilization with preservation of grip function is the goal of any therapy for these injuries. Osteosyntheses with plates are used in complex fractures that do not allow any other treatment. The aim of this retrospective study ... Read more >>

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DXA reference values of the humanoid sheep model in preclinical studies.

Christoph Biehl, Jakob Schmitt, Sabine Stoetzel, Deeksha Malhan, Fathi Hassan, Gero Knapp, Christian Heiss, Thaqif El Khassawna,

<h4>Background</h4>Merino land sheep are a popular pre-clinical large animal model in research on systemic skeletal diseases such as osteoporosis. Interpretation of studies is difficult because many reference parameters are missing or not established. This study aims to determine the reference parameters of the skeletal system (peak bone mass = PBM, ... Read more >>

PeerJ (PeerJ)
[2021, 9:e11183]

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Large Animal Model of Osteoporotic Defect Healing: An Alternative to Metaphyseal Defect Model.

Markus Rupp, Christoph Biehl, Deeksha Malhan, Fathi Hassan, Sameh Attia, Sebastian Rosch, Annemarie B Schäfer, Erin McMahon, Marian Kampschulte, Christian Heiss, Thaqif El Khassawna,

Osteoporosis is a common metabolic disorder diagnosed by lower bone density and higher risk of fracture. Fragility fractures because of osteoporosis are associated with high mortality rate. Deep understanding of fracture healing in osteoporosis is important for successful treatment. Therefore, the FDA approved the use of small and large animal ... Read more >>

Life (Basel) (Life (Basel, Switzerland))
[2021, 11(3):]

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Correction: On the quantification of local power densities in a new vibration bioreactor.

David Valentin, Alexandre Presas, Charline Müntze-Röhr, Elisa Mele, Christoph Biehl, Christian Heiss, Wolfram A Bosbach,

[This corrects the article DOI: 10.1371/journal.pone.0245768.]. ... Read more >>

PLoS One (PloS one)
[2021, 16(3):e0248640]

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On the quantification of local power densities in a new vibration bioreactor.

David Valentin, Alexandre Presas, Charline Roehr, Elisa Mele, Christoph Biehl, Christian Heiss, Wolfram A Bosbach,

We investigate the power densities which are obtainable locally in a vibration bioreactor. These reactor systems are of great relevance for research about oncological or antibacterial therapies. Our focus lies on the local liquid pressure caused by resonance vibration in the fluid contained by the reactor's petri dish. We use ... Read more >>

PLoS One (PloS one)
[2021, 16(1):e0245768]

Cited: 1 time

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Ultrasound-Accelerated Thrombolysis in High-Risk Perioperative Pulmonary Embolism: Two Case Reports and Review of Literature

Götz Schmidt, Fabian Edinger, Christian Koch, Matthias Wolff, Christoph Biehl, Rüdiger Hörbelt, Michael Sander,

<h4>Background: </h4> Treatment of high-risk pulmonary embolism (PE) in perioperative patients remains challenging. Systemic thrombolysis is associated with a high risk of major bleedings and intracranial haemorrhage. High mortality rates are reported for open pulmonary embolectomy. Therefore, postoperative surgical patients may benefit substantially from catheter-directed ultrasound-accelerated thrombolysis (USAT). Case summary: ... Read more >>

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Evidence of Prolonged Monitoring of Trauma Patients Admitted via Trauma Resuscitation Unit without Primary Proof of Severe Injuries.

Martin Heinrich, Matthias Lany, Lydia Anastasopoulou, Christoph Biehl, Gabor Szalay, Florian Brenck, Christian Heiss,

Introductio: Although management of severely injured patients in the Trauma Resuscitation Unit (TRU) follows evidence-based guidelines, algorithms for treatment of the slightly injured are limited.<h4>Methods</h4>All trauma patients in a period of eight months in a Level I trauma center were followed. Retrospective analysis was performed only in patients ≥18 years ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(8):]

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Peri-Prosthetic Joint Infection after Finger Joint Arthroplasty.

Christoph Biehl, Markus Rupp, Volker Alt, Christian Heiss, Thaqif El Khasswana, Gabor Szalay,

<b><i>Background:</i></b> Endoprosthetic treatment of finger joints is an established procedure. However, data on peri-prosthetic finger joint infections (PJI) are rare. The goal of this retrospective study was to assess infection rates and treatment outcomes after PJI of the finger joints. <b><i>Methods:</i></b> Between 1984 and 2014, 1,195 finger joints (978 metacarpal ... Read more >>

Surg Infect (Larchmt) (Surgical infections)
[2020, 21(5):445-450]

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Treatment of proximal fifth metatarsal fractures with an ulna hook plate.

Abdullah Ismat, Markus Rupp, Gero Knapp, Christian Heiss, Gabor Szalay, Christoph Biehl,

<h4>Introduction</h4>Fractures of the base of the fifth metatarsal bone present one of the commonest fractures of the metatarsal bones. Conventionally intramedullary screws and tension band wiring have been used as internal fixation methods. Lately hook plates have also served as an alternative fixation method. We hereby report on our experience ... Read more >>

Foot (Edinb) (Foot (Edinburgh, Scotland))
[2020, 42:101653]

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Computed tomography for managing periprosthetic femoral fractures. A retrospective analysis.

Markus Rupp, Stefanie Kern, Abdullah Ismat, Thaqif El Khassawna, Gero Knapp, Gabor Szalay, Christian Heiss, Christoph Biehl,

<h4>Background</h4>Periprosthetic fractures (PPF) present a common cause for revision surgery after arthroplasty. The choice of performing either an osteosynthesis or revision arthroplasty depends on the orthopedic implant anchored and loosening. Standard diagnostics include x-ray imaging. CT is usually performed to confirm implant loosening in case of ambiguous diagnosis on standard ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2019, 20(1):258]

Cited: 1 time

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Radiocarpal fusion and midcarpal resection interposition arthroplasty: long-term results in severely destroyed rheumatoid wrists.

Christoph Biehl, Thomas Braun, Ulrich Thormann, Amir Oda, Gabor Szalay, Stefan Rehart,

<h4>Background</h4>The aim of this retrospective study is to evaluate distal resection interposition arthroplasty of the wrist as a tool to restore mobility as well as to restore stability in severely destroyed wrist joints.<h4>Methods</h4>Thirty-four wrists in 28 rheumatoid arthritis patients were included. The mean follow-up time was 9 years after surgical treatment ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2018, 19(1):286]

Cited: 3 times

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Osteocytes.

Markus Rupp, Felix Merboth, Diaa Eldin Daghma, Christoph Biehl, Thaqif El Khassawna, Christian Heiß,

For a long time, osteocytes were regarded as passive bystanders of bone metabolism. Bone remodeling was considered to be an interplay between bone forming osteoblasts and bone degrading osteoclasts. However, the dogma of osteocytes as bystanders within the bone has changed fundamentally since the turn of the millenium. Rather than ... Read more >>

Z Orthop Unfall (Zeitschrift fur Orthopadie und Unfallchirurgie)
[2019, 157(2):154-163]

Cited: 1 time

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Diaphyseal long bone nonunions - types, aetiology, economics, and treatment recommendations.

Markus Rupp, Christoph Biehl, Matthäus Budak, Ulrich Thormann, Christian Heiss, Volker Alt,

The intention of the current article is to review the epidemiology with related socioeconomic costs, pathophysiology, and treatment options for diaphyseal long bone delayed unions and nonunions. Diaphyseal nonunions in the tibia and in the femur are estimated to occur 4.6-8% after modern intramedullary nailing of closed fractures with an ... Read more >>

Int Orthop (International orthopaedics)
[2018, 42(2):247-258]

Cited: 27 times

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Strontium and bisphosphonate coated iron foam scaffolds for osteoporotic fracture defect healing.

Seemun Ray, Ulrich Thormann, Marlen Eichelroth, Matthäus Budak, Christoph Biehl, Markus Rupp, Ursula Sommer, Thaqif El Khassawna, Francisca I Alagboso, Marian Kampschulte, Marcus Rohnke, Anja Henß, Klaus Peppler, Vanessa Linke, Peter Quadbeck, Axel Voigt, Florian Stenger, Daniel Karl, Reinhard Schnettler, Christian Heiss, Katrin S Lips, Volker Alt,

The purpose of this work was to investigate new bone formation in macroporous iron foams coated with strontium (FeSr) or bisphosphonate (FeBiP) compared to plain iron foam (Fe) and empty defect in a critical size metaphyseal bone defect model in ovariectomized rats. 60 female rats were subjected to bilateral ovariectomy ... Read more >>

Biomaterials (Biomaterials)
[2018, 157:1-16]

Cited: 6 times

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Pilot study for the registry of complications in rheumatic diseases from the German Society of Surgery (DGORh): evaluation of methods and data from the first 1000 patients.

Tanja Kostuj, Stefan Rehart, Ronald Matta-Hurtado, Christoph Biehl, Roland E Willburger, Klaus Schmidt, ,

<h4>Objective</h4>Most patients suffering with rheumatic diseases who undergo surgical treatment are receiving immune-modulating therapy. To determine whether these medications affect their outcomes a national registry was established in Germany by the German Society of Surgery (DGORh). Data from the first 1000 patients were used in a pilot study to identify ... Read more >>

BMJ Open (BMJ open)
[2017, 7(10):e015987]

Cited: 0 times

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