Isabel Fernández de Mera, Francisco Rodríguez del Río, José de la Fuente, Marta Pérez Sancho, Dolores Hervas, Inma Moreno, Mercedes Dominguez, Lucas Domínguez, Christian Gortázar,
Background: Since March 2020, Spain is severely hit by the ongoing pandemic of coronavirus disease 19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Understanding and disrupting the early transmission dynamics of the infection is crucial for impeding sustained transmission. Methods: We recorded all COVID-19 cases and traced ... Read more >>
Cited: 0 times
Jordi Martínez-Guijosa, Beatriz Romero, José Antonio Infantes-Lorenzo, Elena Díez, Mariana Boadella, Ana Balseiro, Miguel Veiga, David Navarro, Inmaculada Moreno, Javier Ferreres, Mercedes Domínguez, Cesar Fernández, Lucas Domínguez, Christian Gortázar,
Attaining and maintaining the Official Tuberculosis Free status continues to be a challenge when several domestic and wild hosts contribute to the maintenance of the Mycobacterium tuberculosis complex (MTC). Local tuberculosis hotspots are sometimes identified in cattle in low-prevalence regions. We have, therefore, studied one such hotspot in depth in ... Read more >>
PLoS ONE (PloS one)
[2020, 15(5):e0233837]
Cited: 0 times
Christian Gortázar, José de la Fuente,
Responses to the ongoing COVID-19 pandemic have included travel bans and social distancing with "shelter in place" orders, resulting in sudden changes in human activity and subsequent effects on the global and national economy. We speculate that animal health will likely be impacted by COVID-19 through the immediate consequences of ... Read more >>
Prev. Vet. Med. (Preventive veterinary medicine)
[2020, 180:105030]
Cited: 0 times
Iván Pacheco, Marinela Contreras, Margarita Villar, María Angeles Risalde, Pilar Alberdi, Alejandro Cabezas-Cruz, Christian Gortázar, José de la Fuente,
The alpha-Gal syndrome (AGS) is associated with tick bites that can induce in humans high levels of IgE antibodies against the carbohydrate Galα1-3Galβ1-(3)4GlcNAc-R (α-Gal) present in glycoproteins and glycolipids from tick saliva that mediate primarily delayed anaphylaxis to mammalian meat consumption. It has been proposed that humans evolved by losing ... Read more >>
Vaccines (Basel) (Vaccines)
[2020, 8(2):]
Cited: 0 times
Xander O'Neill, Andy White, Francisco Ruiz-Fons, Christian Gortázar,
African swine fever (ASF) is a severe viral disease that is currently spreading among domestic pigs and wild boar (Sus scrofa) in large areas of Eurasia. Wild boar play a key role in the spread of ASF, yet despite their significance, little is known about the key mechanisms that drive ... Read more >>
Sci Rep (Scientific reports)
[2020, 10(1):5895]
Cited: 0 times
Jose A Barasona, Sandra Barroso-Arévalo, Belén Rivera, Christian Gortázar, Jose M Sánchez-Vizcaíno,
The presence of Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex (MTC) is a main concern in wildlife populations such as the Eurasian wild boar (Sus scrofa). Tests detecting antibodies against the MTC are valuable for tuberculosis (TB) monitoring and control and particularly useful in suids. The development ... Read more >>
Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(4):]
Cited: 0 times
Ana Águeda-Pinto, Simona Kraberger, Michael C Lund, Christian Gortázar, Grant McFadden, Arvind Varsani, Pedro J Esteves,
Viruses are ubiquitous in nature; however, very few have been identified in the Leporid species. In the fall of 2018, an outbreak of myxomatosis in Iberian hares (Lepus granatensis) was reported in Spain and a novel recombinant myxoma virus strain (MYXV-Tol) was identified. To investigate variability within the recombinant region ... Read more >>
Viruses (Viruses)
[2020, 12(3):]
Cited: 0 times
Pauline Nol, Morgan E Wehtje, Richard A Bowen, Suelee Robbe-Austerman, Tyler C Thacker, Kristina Lantz, Jack C Rhyan, Laurie A Baeten, Ramón A Juste, Iker A Sevilla, Christian Gortázar, Joaquín Vicente,
The wild pig population on Molokai, Hawaii, USA is a possible reservoir for bovine tuberculosis, caused by Mycobacterium bovis, and has been implicated in decades past as the source of disease for the island's domestic cattle. Heat-inactivated vaccines have been effective for reducing disease prevalence in wild boar in Spain ... Read more >>
Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(3):]
Cited: 0 times
Yeong-Seok Jo, Christian Gortázar,
South Korea is the only Asian country where African swine fever (ASF) is spreading in wild boar (Sus scrofa) populations. This rapid communication describes the situation of ASF in South Korea since its first detection on 17 September 2019 with special attention to ASF dynamics and management in wild boar. ... Read more >>
Transbound Emerg Dis (Transboundary and emerging diseases)
[2020, :]
Cited: 0 times
Julio Isla, Mariana Boadella, Jose Antonio Ortiz, Christian Gortázar,
Mycobacterial diseases are important health issues in farmed deer. The single intradermal tuberculin test is the standard test for tuberculosis testing in deer. We studied two factors which might influence the response of deer to skin testing: the inoculation site and the injection device. Deer included in this study were ... Read more >>
Prev. Vet. Med. (Preventive veterinary medicine)
[2020, 176:104932]
Cited: 0 times
José Antonio Infantes-Lorenzo, Christian Gortázar, Lucas Domínguez, Marta Muñoz-Mendoza, Mercedes Domínguez, Ana Balseiro,
Recent studies show that sheep could be considered to be a maintenance host for the causative agents of animal tuberculosis (TB). The performance of diagnostic tests is not well established, and new tests need to be developed for this species. In addition, information about TB prevalence in sheep is scarce. ... Read more >>
Res. Vet. Sci. (Research in veterinary science)
[2020, 129:96-98]
Cited: 0 times
Maria Angeles Risalde, Álvaro Roy, Javier Bezos, Carmen Pineda, Carmen Casal, Alberto Díez-Guerrier, Ignacio Lopez-Villalba, Álvaro Fernández-Manzano, Inmaculada Moreno, Lucía De Juan, Lucas Domínguez, Christian Gortazar,
BACKGROUND:There is evidence for a link between vitamin D deficiency and active tuberculosis (TB). In human beings, several trials have evaluated the role of vitamin D supplementation in TB treatment with conflicting results. However, the role of vitamin D supplementation in animal TB control has received less attention. The authors ... Read more >>
Vet. Rec. (The Veterinary record)
[2019, 185(24):759]
Cited: 0 times
José de la Fuente, Marinela Contreras, Paul D Kasaija, Christian Gortazar, Jose F Ruiz-Fons, Rafael Mateo, Fredrick Kabi,
A meeting and course supported by the Vice-Presidency for International Affairs of the Spanish National Research Council (CSIC) and the National Agricultural Research Organization of Uganda (NARO) were held at the National Livestock Resources Research Institute (NaLIRRI) in Nakyesasa, Wakiso, Uganda on September 2-9, 2019. The activities were conducted within ... Read more >>
Vaccines (Basel) (Vaccines)
[2019, 7(4):]
Cited: 0 times
Alvaro Roy, Irene Tomé, Beatriz Romero, Víctor Lorente-Leal, José A Infantes-Lorenzo, Mercedes Domínguez, Carlos Martín, Nacho Aguiló, Eugenia Puentes, Esteban Rodríguez, Lucía de Juan, María A Risalde, Christian Gortázar, Lucas Domínguez, Javier Bezos,
Effective vaccines against tuberculosis (TB) are needed in order to prevent TB transmission in human and animal populations. Evaluation of TB vaccines may be facilitated by using reliable animal models that mimic host pathophysiology and natural transmission of the disease as closely as possible. In this study, we evaluated the ... Read more >>
Vet. Res. (Veterinary research)
[2019, 50(1):82]
Cited: 0 times
Michele A Miller, Christian Gortazar, Eduard O Roos, Maria A Risalde, Ashley Johnathan-Lee, Archana A Sridhara, Konstantin P Lyashchenko,
Domestic pigs and wild suids are susceptible to Mycobacterium bovis (M. bovis) infection and may even serve as reservoir hosts in some situations. Therefore, detection of infected animals is important for understanding their role in the epidemiology of the disease as well as for management and control of bovine tuberculosis. ... Read more >>
Vet. Microbiol. (Veterinary microbiology)
[2019, 235:285-288]
Cited: 0 times
Iratxe Díez-Delgado, Iker A Sevilla, Joseba M Garrido, Beatriz Romero, María V Geijo, Lucas Dominguez, Ramón A Juste, Alicia Aranaz, José de la Fuente, Christian Gortazar,
The Eurasian wild boar (Sus scrofa) is a reservoir for tuberculosis (TB) in which vaccination is a valuable tool for control. We evaluated the protection and immune response achieved by homologous and heterologous regimes administering BCG and heat-inactivated Mycobacterium bovis (IV). Twenty-one wild boar piglets were randomly allocated in five ... Read more >>
Comp. Immunol. Microbiol. Infect. Dis. (Comparative immunology, microbiology and infectious diseases)
[2019, 66:101329]
Cited: 0 times
Alba Fresco-Taboada, María A Risalde, Christian Gortázar, Istar Tapia, Isabel González, Ángel Venteo, Antonio Sanz, Paloma Rueda,
The native Eurasian wild boar (Sus scrofa) is a reservoir of Mycobacterium bovis, the causative agent of animal tuberculosis (TB), a chronic disease in livestock, companion animals and wild mammals. Cases of M. bovis infection in wild boar or feral pig have been reported worldwide, making early detection a priority in ... Read more >>
Transbound Emerg Dis (Transboundary and emerging diseases)
[2019, 66(5):2175-2179]
Cited: 0 times
Jose Angel Barasona, Christian Gortázar, José de la Fuente, Joaquín Vicente,
Current scientific debate addresses whether species richness in animal communities may negatively moderate pathogen transmission and disease outcome (dilution effect), or to the contrary, if disease emergence benefits from more diverse community assemblages (amplification effect). The result may not depend exclusively on patterns of host species biodiversity but may depend ... Read more >>
Microorganisms (Microorganisms)
[2019, 7(6):]
Cited: 0 times
Joaquín Vicente, Marco Apollonio, Jose A Blanco-Aguiar, Tomasz Borowik, Francesca Brivio, Jim Casaer, Simon Croft, Göran Ericsson, Ezio Ferroglio, Dolores Gavier-Widen, Christian Gortázar, Patrick A Jansen, Oliver Keuling, Rafał Kowalczyk, Karolina Petrovic, Radim Plhal, Tomasz Podgórski, Marie Sange, Massimo Scandura, Krzysztof Schmidt, Graham C Smith, Ramon Soriguer, Hans-Hermann Thulke, Stefania Zanet, Pelayo Acevedo,
Science (Science (New York, N.Y.))
[2019, 364(6444):943-944]
Cited: 0 times
Eleanor Tanner, Andy White, Peter W W Lurz, Christian Gortázar, Iratxe Díez-Delgado, Mike Boots,
Despite the ubiquity of disease in nature, the role that disease dynamics play in the compensatory growth response to harvesting has been ignored. We use a mathematical approach to show that harvesting can lead to compensatory growth due to a release from disease-induced mortality. Our findings imply that culling in ... Read more >>
Am. Nat. (The American naturalist)
[2019, 194(1):E1-E12]
Cited: 0 times
Ana Águeda-Pinto, Ana Lemos de Matos, Mário Abrantes, Simona Kraberger, Maria Risalde, Christian Gortázar, Grant McFadden, Arvind Varsani, Pedro Esteves,
Abstract Myxomatosis is a lethal disease of wild European and domestic rabbits ( Oryctolagus cuniculus ) caused by a Myxoma virus (MYXV) infection, a leporipoxvirus that is found naturally in some Sylvilagus rabbit species in South America and California. The introduction of MYXV in the early 1950s into feral European ... Read more >>
Cited: 0 times
Marinela Contreras, Paul D Kasaija, Octavio Merino, Ned I de la Cruz-Hernandez, Christian Gortazar, José de la Fuente,
Vaccines are an environmentally friendly alternative to acaracides for the control of tick infestations, to reduce the risk for tick-borne diseases affecting human and animal health worldwide, and to improve animal welfare and production. Subolesin (SUB, also known as 4D8) is the functional homolog of Akirin2 involved in the regulation ... Read more >>
Front Cell Infect Microbiol (Frontiers in cellular and infection microbiology)
[2019, 9:45]
Cited: 1 time
João Queirós, Pelayo Acevedo, João P V Santos, Jose Barasona, Beatriz Beltran-Beck, David González-Barrio, Jose A Armenteros, Iratxe Diez-Delgado, Mariana Boadella, Isabel Fernandéz de Mera, Jose F Ruiz-Fons, Joaquin Vicente, Jose de la Fuente, Christian Gortázar, Jeremy B Searle, Paulo C Alves,
The red deer (Cervus elaphus) is a widespread wild ungulate in Europe that has suffered strong anthropogenic impacts over their distribution during the last centuries, but also at the present time, due its economic importance as a game species. Here we focus on the evolutionary history of the red deer ... Read more >>
PLoS ONE (PloS one)
[2019, 14(1):e0210282]
Cited: 0 times
Jose A Infantes-Lorenzo, Dipesh Dave, Immaculada Moreno, Paul Anderson, Sandrine Lesellier, Eamonn Gormley, Lucas Dominguez, Ana Balseiro, Christian Gortázar, Mercedes Dominguez, Francisco J Salguero,
European badgers (Meles meles) have been identified as wildlife reservoirs for Mycobacterium bovis in the UK and Ireland, and may also have a role in the epidemiology of animal tuberculosis in other European regions. Thus, detection of M. bovis-infected badgers may be required for the purposes of surveillance and monitoring of ... Read more >>
Vet Med Sci (Veterinary medicine and science)
[2019, 5(1):61-69]
Cited: 0 times
João Queirós, Margarita Villar, Angélica Hernández-Jarguín, Vladimir López, Isabel Fernández de Mera, Joaquín Vicente, Paulo C Alves, Christian Gortazar, José de la Fuente,
Constraints in the characterization of microbiota community that circulates in the host have limited the extent of co-infection studies in natural populations. In this study, we used a metaproteomics approach to characterize the mandibular lymph nodes microbiota of wild boar (Sus scrofa) naturally exposed to an increasing trend of Mycobacterium ... Read more >>
Tuberculosis (Edinb) (Tuberculosis (Edinburgh, Scotland))
[2019, 114:103-112]
Cited: 0 times