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Author Christian Apfelbacher

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Incidence and Mortality of Malignant Melanoma in Relation to Dermatologist Density in Bavaria.

Konstantin Drexler, Hans Drexler, Edward K Geissler, Mark Berneburg, Sebastian Haferkamp, Christian Apfelbacher,

<h4>Introduction</h4>Malignant melanoma is an aggressive skin tumor with a good prognosis when treated in an early tumor stage, but has a poor prognosis with distant metastases. The incidence of malignant melanoma has increased continuously over the last decades, with little change in mortality. One explanation for this is that melanomas ... Read more >>

Adv Ther (Advances in therapy)
[2021, :]

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Feasibility of a surveillance programme based on gargle samples and pool testing to prevent SARS-CoV-2 outbreaks in schools.

Catherine M Sweeney-Reed, Doreen Wolff, Sarah Hörnschemeyer, Henriette Faßhauer, Antonia Haase, Dirk Schomburg, Jakob Niggel, Michael Kabesch, Christian Apfelbacher,

School closures have a negative impact on physical and mental well-being, and education, of children and adolescents. A surveillance programme to detect asymptomatic SARS-CoV-2 infection could allow schools to remain open, while protecting the vulnerable. We assessed the feasibility of a programme employing gargle samples and pool testing of individually ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):19521]

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CoronaCare study protocol: an ethnographic study of the risks to and potential for social health during the COVID-19 pandemic.

Joshua Paul, Sibille Merz, Andreas Bergholz, Franziska König, Christian Apfelbacher, Astrid Eich-Krohm, Julia Weigt, Christine Holmberg,

<h4>Introduction</h4>German government regulations such as physical distancing and limited group numbers, designed to curb the spread of COVID-19, have had far-reaching consequences for the very foundations of social life. They have, to name only a few, transformed greetings and goodbyes, blurred private and public worlds, and complicated basic communication with ... Read more >>

BMJ Open (BMJ open)
[2021, 11(10):e048212]

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Determinants of maternal health four weeks after delivery: cross-sectional findings from the KUNO-kids health study.

Veronika Pinker, Susanne Brandstetter, Christina Tischer, Birgit Seelbach-Göbel, Michael Melter, Michael Kabesch, Christian Apfelbacher, ,

<h4>Background</h4>The aim of this study was to examine the interaction of a multitude of socio-economic, lifestyle, environmental, psychosocial and birth related determinants and their effect on maternal health four weeks after delivery.<h4>Methods</h4>We used data from a German birth cohort study, the KUNO-Kids health study. Social determinants, as well as the ... Read more >>

BMC Public Health (BMC public health)
[2021, 21(1):1676]

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Incidence and risk factors for persistent symptoms in adults previously hospitalized for COVID-19.

Daniel Munblit, Polina Bobkova, Ekaterina Spiridonova, Anastasia Shikhaleva, Aysylu Gamirova, Oleg Blyuss, Nikita Nekliudov, Polina Bugaeva, Margarita Andreeva, Audrey DunnGalvin, Pasquale Comberiati, Christian Apfelbacher, Jon Genuneit, Sergey Avdeev, Valentina Kapustina, Alla Guekht, Victor Fomin, Andrey A Svistunov, Peter Timashev, Vladislav S Subbot, Valery V Royuk, Thomas M Drake, Sarah Wulf Hanson, Laura Merson, Gail Carson, Peter Horby, Louise Sigfrid, Janet T Scott, Malcolm G Semple, John O Warner, Theo Vos, Piero Olliaro, Petr Glybochko, Denis Butnaru, ,

<h4>Background</h4>The long-term sequalae of COVID-19 remain poorly characterized. We assessed persistent symptoms in previously hospitalized patients with COVID-19 and assessed potential risk factors.<h4>Methods</h4>Data were collected from patients discharged from 4 hospitals in Moscow, Russia between 8 April and 10 July 2020. Participants were interviewed via telephone using an ISARIC Long-term Follow-up Study questionnaire.<h4>Results</h4>2,649 ... Read more >>

Clin Exp Allergy (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology)
[2021, 51(9):1107-1120]

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Measurement properties of patient-reported outcome measures (PROMs) in hyperhidrosis: a systematic review.

Michaela Gabes, Helge Knüttel, Gesina Kann, Christina Tischer, Christian J Apfelbacher,

<h4>Purpose</h4>To critically appraise, compare and summarize the quality of all existing PROMs that have been validated in hyperhidrosis to at least some extend by applying the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology. Thereby, we aim to give a recommendation for the use of PROMs in ... Read more >>

Qual Life Res (Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation)
[2021, :]

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The evidence for interventions in early childhood allergy prevention – towards a living systematic review: protocol

Uwe Matterne, Christina Tischer, Jiancong Wang, Helge Knüttel, Jon Genuneit, Michael Perkin, Christian Apfelbacher,

<ns3:p> <h4>Background: </h4> Research in early childhood allergy prevention (ECAP) is flourishing and new intervention strategies have proven to be promising. Due to the dynamic nature of ECAP, gaps between what is known and how guidelines inform practice are likely. A living systematic review (LSR) can narrow this gap by ... Read more >>

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Utilisation of Prenatal Diagnostics During Pregnancy in Germany: Cross-sectional Study Using Data From the KUNO Kids Health Study

Johanna Mayer, Susanne Brandstetter, Christina Tischer, Birgit Seelbach-Göbel, Sara Fill Malfertheiner, Michael Melter, Michael Kabesch, Christian Apfelbacher,

<h4>Background: </h4> Appropriate health system utilisation during pregnancy is fundamental for maintaining maternal and child’s health. This study provides comprehensive data on supplementary prenatal diagnostics use and its influencing factors in Germany. <h4>Methods: </h4>: We obtained data from a recently established prospective German birth cohort study, the KUNO Kids Health ... Read more >>

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Risk factors for long covid in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study.

Ismail M Osmanov, Ekaterina Spiridonova, Polina Bobkova, Aysylu Gamirova, Anastasia Shikhaleva, Margarita Andreeva, Oleg Blyuss, Yasmin El-Taravi, Audrey DunnGalvin, Pasquale Comberiati, Diego G Peroni, Christian Apfelbacher, Jon Genuneit, Lyudmila Mazankova, Alexandra Miroshina, Evgeniya Chistyakova, Elmira Samitova, Svetlana Borzakova, Elena Bondarenko, Anatoliy A Korsunskiy, Irina Konova, Sarah Wulf Hanson, Gail Carson, Louise Sigfrid, Janet T Scott, Matthew Greenhawt, Elizabeth A Whittaker, Elena Garralda, Olivia Swann, Danilo Buonsenso, Dasha E Nicholls, Frances Simpson, Christina Jones, Malcolm G Semple, John O Warner, Theo Vos, Piero Olliaro, Daniel Munblit, ,

<h4>Background</h4>The long-term sequelae of coronavirus disease 2019 (Covid-19) in children remain poorly characterised. This study aimed to assess long-term outcomes in children previously hospitalised with Covid-19 and associated risk factors.<h4>Methods</h4>This is a prospective cohort study of children (≤18 years old) admitted with confirmed Covid-19. Children admitted to the hospital between April ... Read more >>

Eur Respir J (The European respiratory journal)
[2021, :]

Cited: 9 times

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The association of childhood maltreatment, somatization and health-related quality of life in adult age: Results from a population-based cohort study.

Katharina Piontek, Ulrich Wiesmann, Christian Apfelbacher, Henry Völzke, Hans Jörgen Grabe,

<h4>Background</h4>Population-based data regarding the relationship between childhood maltreatment (CM), somatization and health-related quality of life (HRQoL) in adults are limited.<h4>Objective</h4>To investigate the association of CM history (emotional and physical abuse and neglect, sexual abuse) with somatization and with physical and mental HRQoL in adults.<h4>Participants and setting</h4>Data from 2305 participants from ... Read more >>

Child Abuse Negl (Child abuse & neglect)
[2021, 120:105226]

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Families`worries During the First and Second COVID-19 Wave in Germany: Comparative Longitudinal Study in Two Populational Childhood Cohorts

Susanne Brandstetter, Tanja Poulain, Mandy Vogel, Christof Meigen, Michael Melter, Angela Köninger, Christian Apfelbacher, Wieland Kiess, Michael Kabesch, Antje Körner,

<h4>Background: </h4> The present study aimed to compare worries related to the Coronavirus disease 2019 (COVID-19) in families with young children in two regions in Germany differently affected by the pandemic (Regensburg in Southeast Germany, Leipzig in Eastern Germany) during the first and the second wave of the COVID-19 pandemicMethods720 ... Read more >>

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Frequency of hand eczema in the elderly: Cross-sectional findings from the German AugUR study.

Karl Philipp Drewitz, Klaus J Stark, Martina E Zimmermann, Iris M Heid, Christian J Apfelbacher,

<h4>Background</h4>Hand eczema (HE) is a chronic inflammatory skin disease caused by a genetic predisposition and environmental exposures. There is a lack of population-based studies on skin diseases in the elderly.<h4>Objectives</h4>Our aim was to estimate the frequency of HE in the elderly to determine its burden of disease in this particular ... Read more >>

Contact Dermatitis (Contact dermatitis)
[2021, :]

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Experiences, opinions and expectations of health care providers towards an intensive care unit follow-up clinic: Qualitative study and online survey.

Magdalena Rohr, Annette Weiß, Thomas Bein, Christine Bernardi, Susanne Brandstetter, Karl Philipp Drewitz, Christoph Fisser, Julika Loss, Maximilian Malfertheiner, Christian Apfelbacher,

<h4>Objectives</h4>Independent of the underlying disease, intensive care unit survivors often suffer from cognitive, physical and mental impairments, also known as post-intensive care syndrome (PICS). Specific follow-up services are recommended for these patients. This study aims to capture the perspectives of health care providers on the development of the first intensive ... Read more >>

Intensive Crit Care Nurs (Intensive & critical care nursing)
[2021, :103084]

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Evaluation of Undescended Testes in Newborns: It Is Really Simple, Just Not Easy.

Martin Promm, Annika Dittrich, Susanne Brandstetter, Sara Fill-Malfertheiner, Michael Melter, Birgit Seelbach-Göbel, Christian Apfelbacher, Michael Kabesch, Wolfgang H Rösch, ,

<h4>Introduction</h4>The evaluation of the testicular position in newborns is important to ensure timely initiation of therapy. The aim of our study was to assess the reliability of a routinely performed screening examination.<h4>Patients and methods</h4>Newborns were examined by a pediatrician between 48 and 72 h after birth. Boys with suspected cryptorchidism ... Read more >>

Urol Int (Urologia internationalis)
[2021, :1-5]

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Stop COVID Cohort: An Observational Study of 3480 Patients Admitted to the Sechenov University Hospital Network in Moscow City for Suspected Coronavirus Disease 2019 (COVID-19) Infection.

Daniel Munblit, Nikita A Nekliudov, Polina Bugaeva, Oleg Blyuss, Maria Kislova, Ekaterina Listovskaya, Aysylu Gamirova, Anastasia Shikhaleva, Vladimir Belyaev, Peter Timashev, John O Warner, Pasquale Comberiati, Christian Apfelbacher, Evgenii Bezrukov, Mikhail E Politov, Andrey Yavorovskiy, Ekaterina Bulanova, Natalya Tsareva, Sergey Avdeev, Valentina A Kapustina, Yuri I Pigolkin, Emmanuelle A Dankwa, Christiana Kartsonaki, Mark G Pritchard, Victor Fomin, Andrey A Svistunov, Denis Butnaru, Petr Glybochko, ,

<h4>Background</h4>The epidemiology, clinical course, and outcomes of patients with coronavirus disease 2019 (COVID-19) in the Russian population are unknown. Information on the differences between laboratory-confirmed and clinically diagnosed COVID-19 in real-life settings is lacking.<h4>Methods</h4>We extracted data from the medical records of adult patients who were consecutively admitted for suspected COVID-19 ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, 73(1):1-11]

Cited: 12 times

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Quality of life in atopic dermatitis in Asian countries: a systematic review.

Jinghui Huang, Yue Jia Choo, Helen Elizabeth Smith, Christian Apfelbacher,

Atopic dermatitis (AD) is a common chronic inflammatory skin condition which impacts psychological wellbeing and social relationships. There have been studies of AD's impact on quality of life (QoL) in Western countries, but these findings cannot be directly extrapolated to Asian populations with genetic, environmental and cultural differences. Therefore, we ... Read more >>

Arch Dermatol Res (Archives of dermatological research)
[2021, :]

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Reply to Russo et al.

Daniel Munblit, Nikita A Nekliudov, Polina Bugaeva, Oleg Blyuss, Peter Timashev, John O Warner, Pasquale Comberiati, Christian Apfelbacher, Mikhail E Politov, Andrey Yavorovskiy, Sergey Avdeev, Valentina A Kapustina, Victor Fomin, Andrey A Svistunov, Denis Butnaru, Petr Glybochko,

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, 72(12):e1159-e1160]

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Measurement properties of patient-reported outcome measures (PROMs) in patients with hyperhidrosis: protocol for a systematic review.

Michaela Gabes, Helge Knüttel, Christian J Apfelbacher,

<h4>Background</h4>Hyperhidrosis is a chronic skin condition that impairs the patient's quality of life (QoL). There are several patient-reported outcome measures (PROMs) for patients affected by hyperhidrosis available; however an evidence-based assessment of their quality has not been undertaken so far.<h4>Objective</h4>In our systematic review, we aim to identify all existing PROMs ... Read more >>

Syst Rev (Systematic reviews)
[2021, 10(1):163]

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Stigmatization from Work-Related COVID-19 Exposure: A Systematic Review with Meta-Analysis.

Melanie Schubert, Julia Ludwig, Alice Freiberg, Taurai Monalisa Hahne, Karla Romero Starke, Maria Girbig, Gudrun Faller, Christian Apfelbacher, Olaf von dem Knesebeck, Andreas Seidler,

Stigmatization from work-related COVID-19 exposure has not been investigated in detail yet. Therefore, we systematically searched three databases: Medline, Embase, and PsychInfo (until October 2020), and performed a grey literature search (until February 2021). We identified 46 suitable articles from 24 quantitative and 11 qualitative studies, 6 systematic reviews, 3 ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2021, 18(12):]

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Pool Testing as a Strategy for Prevention of SARS-CoV-2 Outbreaks in Schools: Protocol for a Feasibility Study.

Catherine M Sweeney-Reed, Doreen Wolff, Jakob Niggel, Michael Kabesch, Christian Apfelbacher,

<h4>Background</h4>School closures are a widely implemented strategy for limiting infection spread in the current COVID-19 pandemic. The negative impact of school closures on children and young people is increasingly apparent, however.<h4>Objective</h4>We aim to evaluate the feasibility of an infection monitoring program in schools to enable targeted quarantining to replace school ... Read more >>

JMIR Res Protoc (JMIR research protocols)
[2021, 10(5):e28673]

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Validation of the German Day-to-Day Impact of Vaginal Aging (DIVA) Questionnaire in Peri- and Postmenopausal Women.

Michaela Gabes, Petra Stute, Christian Apfelbacher,

<h4>Background</h4>The Day-to-Day Impact of Vaginal Aging (DIVA) questionnaire is a validated patient-reported outcome measure (PROM) capturing the impacts of vaginal symptoms in postmenopausal women.<h4>Aim</h4>We aimed to psychometrically validate the German version of the DIVA questionnaire.<h4>Methods</h4>Data was collected online and by paper-pencil. We ran confirmatory factor analyses to confirm the a ... Read more >>

Sex Med (Sexual medicine)
[2021, 9(4):100382]

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Food allergy in infants assessed in two German birth cohorts 10 years after the EuroPrevall Study

Daniela Roehrl, Susanne Brandstetter, Linda Siziba, Dietrich Rothenbacher, Vincent Gaertner, Susanne Harner, Angela Köninger, Christian Apfelbacher, Michael Melter, Jon Genuneit, Michael Kabesch,

<h4>Background: </h4> The prevalence of food allergies (FA) in children increased rapidly at the turn of the century. The EuroPrevall study identified Germany as a country with very high prevalence of FA at that time. Using two large German birth cohorts we provide an update of the status quo ten ... Read more >>

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Breastfeeding behavior is not associated with health literacy: evidence from the German KUNO-Kids birth cohort study.

Teresa M Graus, Susanne Brandstetter, Birgit Seelbach-Göbel, Michael Melter, Michael Kabesch, Christian Apfelbacher, Sara Fill Malfertheiner, ,

<h4>Purpose</h4>Despite the health benefits of full breastfeeding for both infants and mothers, less than 50% of mothers in Germany practice this method for at least 4 months after childbirth. Because of the growing importance of health literacy to improve public health, we investigated the role of maternal health literacy in breastfeeding ... Read more >>

Arch Gynecol Obstet (Archives of gynecology and obstetrics)
[2021, 304(5):1161-1168]

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Depression Partially Mediates the Association of Adverse Childhood Experiences with Pain Intensity in Patients with Chronic Pelvic Pain Syndrome: Results from a Cross-Sectional Patient Survey.

Katharina Piontek, Christian Apfelbacher, Gesche Ketels, Christian Brünahl, Bernd Löwe,

<h4>Objective</h4>Adverse childhood experiences (ACEs), such as emotional and physical maltreatment, are linked to chronic pelvic pain syndrome (CPPS) in adults. Psychological factors are important in understanding CPPS. We aimed to determine the nature and frequency of ACEs in male and female patients with CPPS and to investigate whether somatic symptoms ... Read more >>

Pain Med (Pain medicine (Malden, Mass.))
[2021, 22(5):1174-1184]

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Risk factors for long covid in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study

Ismail Osmanov, Ekaterina Spiridonova, Polina Bobkova, Aysylu Gamirova, Anastasia Shikhaleva, Margarita Andreeva, Oleg Blyuss, Yasmin El-Taravi, Audrey DunnGalvin, Pasquale Comberiati, Diego Peroni, Christian Apfelbacher, Jon Genuneit, Lyudmila Mazankova, Alexandra Miroshina, Evgeniya Chistyakova, Elmira Samitova, Svetlana Borzakova, Elena Bondarenko, Anatoliy Korsunskiy, Irina Konova, Sarah Wulf Hanson, Gail Carson, Louise Sigfrid, Janet Scott, Matthew Greenhawt, Elizabeth Whittaker, Elena Garralda, Olivia Swann, Danilo Buonsenso, Dasha Nicholls, Frances Simpson, Christina Jones, Malcolm Semple, John Warner, Theo Vos, Piero Olliaro, Daniel Munblit, ,

<h4>Background: </h4> The long-term sequelae of coronavirus disease 2019 (Covid-19) in children remain poorly characterised. This study aimed to assess long-term outcomes in children previously hospitalised with Covid-19 and associated risk factors. Methods This is a prospective cohort study of children (18 years old and younger) admitted with confirmed ... Read more >>

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