Full Text Journal Articles by
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QualDash: Adaptable Generation of Visualisation Dashboards for Healthcare Quality Improvement.

Mai Elshehaly, Rebecca Randell, Matthew Brehmer, Lynn McVey, Natasha Alvarado, Chris P Gale, Roy A Ruddle,

Adapting dashboard design to different contexts of use is an open question in visualisation research. Dashboard designers often seek to strike a balance between dashboard adaptability and ease-of-use, and in hospitals challenges arise from the vast diversity of key metrics, data models and users involved at different organizational levels. In ... Read more >>

IEEE Trans Vis Comput Graph (IEEE transactions on visualization and computer graphics)
[2020, PP:]

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Impact of COVID19 Pandemic on the Incidence and Management of Out of Hospital Cardiac Arrest in Patients Presenting with Acute Myocardial Infarction in England.

Muhammad Rashid, Chris P Gale, Nick Curzen, Peter Ludman, Mark De Belder, Adam Timmis, Mohamed O Mohamed, Thomas F Lüscher, Julian Hains, Jianhua Wu, Ahmad Shoaib, Evangelos Kontopantelis, Chris Roebuck, Tom Denwood, John Deanfield, Mamas A Mamas,

Background Studies have reported significant reduction in acute myocardial infarction (AMI) related hospitalizations during the COVID19 pandemic. However, whether these trends are associated with increased incidence of Out of Hospital Cardiac Arrest (OHCA) in this population is unknown. Methods and Results AMI hospitalizations with OHCA during the COVID19 period (1st ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2020, :e018379]

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Prescription of oral anticoagulants and antiplatelets for stroke prophylaxis in atrial fibrillation: nationwide time series ecological analysis.

Jianhua Wu, Eman S Alsaeed, James Barrett, Marlous Hall, Campbell Cowan, Chris P Gale,

AIMS:To investigate trends in the prescription of oral anticoagulants (OACs) and antiplatelet agents for atrial fibrillation (AF). METHODS AND RESULTS:Prescription data for 450 518 patients with AF from 3352 General Practices in England, was obtained from the GRASP-AF registry, 2009-2018. Annualized temporal trends for OAC and antiplatelet prescription were reported according ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2020, 22(9):1311-1319]

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Place and causes of acute cardiovascular mortality during the COVID-19 pandemic.

Jianhua Wu, Mamas A Mamas, Mohamed O Mohamed, Chun Shing Kwok, Chris Roebuck, Ben Humberstone, Tom Denwood, Thomas Luescher, Mark A de Belder, John E Deanfield, Chris P Gale,

OBJECTIVE:To describe the place and causes of acute cardiovascular death during the COVID-19 pandemic. METHODS:Retrospective cohort of adult (age ≥18 years) acute cardiovascular deaths (n=5 87 225) in England and Wales, from 1 January 2014 to 30 June 2020. The exposure was the COVID-19 pandemic (from onset of the first COVID-19 death ... Read more >>

Heart (Heart (British Cardiac Society))
[2020, :]

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Association between Statins Prescribed for Primary and Secondary Prevention and Major Adverse Cardiac Events among Older Adults with Frailty: A Systematic Review.

Matthew Hale, Hadar Zaman, David Mehdizadeh, Oliver Todd, Harriet Callaghan, Chris P Gale, Andrew Clegg,

BACKGROUND:Statins reduce the risk of major adverse cardiovascular events (MACE), however their clinical benefit for primary and secondary prevention among older adults with frailty is uncertain. This systematic review investigates whether statins prescribed for primary and secondary prevention are associated with reduced MACE among adults aged ≥ 65 years with frailty. METHODS:We conducted ... Read more >>

Drugs Aging (Drugs & aging)
[2020, :]

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Exploring variation in the use of feedback from national clinical audits: a realist investigation.

Natasha Alvarado, Lynn McVey, Joanne Greenhalgh, Dawn Dowding, Mamas Mamas, Chris Gale, Patrick Doherty, Rebecca Randell,

BACKGROUND:National Clinical Audits (NCAs) are a well-established quality improvement strategy used in healthcare settings. Significant resources, including clinicians' time, are invested in participating in NCAs, yet there is variation in the extent to which the resulting feedback stimulates quality improvement. The aim of this study was to explore the reasons ... Read more >>

BMC Health Serv Res (BMC health services research)
[2020, 20(1):859]

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Impact of COVID-19 on percutaneous coronary intervention for ST-elevation myocardial infarction.

Chun Shing Kwok, Chris P Gale, Tim Kinnaird, Nick Curzen, Peter Ludman, Evan Kontopantelis, Jianhua Wu, Tom Denwood, Nadeem Fazal, John Deanfield, Mark A de Belder, Mamas Mamas,

BACKGROUND:The objective of the study was to identify any changes in primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) in England by analysing procedural numbers, clinical characteristics and patient outcomes during the COVID-19 pandemic. METHODS:We conducted a retrospective cohort study of patients who underwent PCI in England between ... Read more >>

Heart (Heart (British Cardiac Society))
[2020, :]

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2020 ESC Guidelines for the management of adult congenital heart disease.

Helmut Baumgartner, Julie De Backer, Sonya V Babu-Narayan, Werner Budts, Massimo Chessa, Gerhard-Paul Diller, Bernard Lung, Jolanda Kluin, Irene M Lang, Folkert Meijboom, Philip Moons, Barbara J M Mulder, Erwin Oechslin, Jolien W Roos-Hesselink, Markus Schwerzmann, Lars Sondergaard, Katja Zeppenfeld, ,

Eur. Heart J. (European heart journal)
[2020, :]

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2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS).

Gerhard Hindricks, Tatjana Potpara, Nikolaos Dagres, Elena Arbelo, Jeroen J Bax, Carina Blomström-Lundqvist, Giuseppe Boriani, Manuel Castella, Gheorghe-Andrei Dan, Polychronis E Dilaveris, Laurent Fauchier, Gerasimos Filippatos, Jonathan M Kalman, Mark La Meir, Deirdre A Lane, Jean-Pierre Lebeau, Maddalena Lettino, Gregory Y H Lip, Fausto J Pinto, G Neil Thomas, Marco Valgimigli, Isabelle C Van Gelder, Bart P Van Putte, Caroline L Watkins, ,

Eur. Heart J. (European heart journal)
[2020, :]

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2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease.

Antonio Pelliccia, Sanjay Sharma, Sabiha Gati, Maria Bäck, Mats Börjesson, Stefano Caselli, Jean-Philippe Collet, Domenico Corrado, Jonathan A Drezner, Martin Halle, Dominique Hansen, Hein Heidbuchel, Jonathan Myers, Josef Niebauer, Michael Papadakis, Massimo Francesco Piepoli, Eva Prescott, Jolien W Roos-Hesselink, A Graham Stuart, Rod S Taylor, Paul D Thompson, Monica Tiberi, Luc Vanhees, Matthias Wilhelm, ,

Eur. Heart J. (European heart journal)
[2020, :]

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2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation.

Jean-Philippe Collet, Holger Thiele, Emanuele Barbato, Olivier Barthélémy, Johann Bauersachs, Deepak L Bhatt, Paul Dendale, Maria Dorobantu, Thor Edvardsen, Thierry Folliguet, Chris P Gale, Martine Gilard, Alexander Jobs, Peter Jüni, Ekaterini Lambrinou, Basil S Lewis, Julinda Mehilli, Emanuele Meliga, Béla Merkely, Christian Mueller, Marco Roffi, Frans H Rutten, Dirk Sibbing, George C M Siontis, ,

Eur. Heart J. (European heart journal)
[2020, :]

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European Society of Cardiology methodology for the development of quality indicators for the quantification of cardiovascular care and outcomes.

Suleman Aktaa, Gorav Batra, Lars Wallentin, Colin Baigent, David Erlinge, Stefan James, Peter Ludman, Aldo P Maggioni, Susanna Price, Clive Weston, Barbara Casadei, Chris P Gale,

AIMS:It is increasingly recognised that tools are required for assessing and benchmarking quality of care in order to improve it. The European Society of Cardiology (ESC) is developing a suite of quality indicators (QIs) to evaluate cardiovascular care and support the delivery of evidence-based care. This paper describes the methodology ... Read more >>

Eur Heart J Qual Care Clin Outcomes (European heart journal. Quality of care & clinical outcomes)
[2020, :]

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Place and causes of acute cardiovascular mortality during the COVID-19 pandemic

Jianhua Wu, Mamas A Mamas, Mohamed O Mohamed, Chun Shing Kwok, Chris Roebuck, Ben Humberstone, Tom Denwood, Thomas Luescher, Mark A de Belder, John E Deanfield, Chris P Gale,

Objective To describe the place and causes of acute cardiovascular death during the COVID-19 pandemic. Methods Retrospective cohort of adult (age ≥18 years) acute cardiovascular deaths (n=5 87 225) in England and Wales, from 1 January 2014 to 30 June 2020. The exposure was the COVID-19 pandemic (from onset of the first ... Read more >>

Heart (Heart (British Cardiac Society))
[2020, :]

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Association of treatments for acute myocardial infarction and survival for seven common comorbidity states: a nationwide cohort study.

Mohammad E Yadegarfar, Chris P Gale, Tatendashe B Dondo, Chris G Wilkinson, Martin R Cowie, Marlous Hall,

BACKGROUND:Comorbidity is common and has a substantial negative impact on the prognosis of patients with acute myocardial infarction (AMI). Whilst receipt of guideline-indicated treatment for AMI is associated with improved prognosis, the extent to which comorbidities influence treatment provision its efficacy is unknown. Therefore, we investigated the association between treatment ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):231]

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Quality indicators for the care and outcomes of adults with atrial fibrillation.

Elena Arbelo, Suleman Aktaa, Andreas Bollmann, André D'Avila, Inga Drossart, Jeremy Dwight, Mellanie True Hills, Gerhard Hindricks, Fred M Kusumoto, Deirdre A Lane, Dennis H Lau, Maddalena Lettino, Gregory Y H Lip, Trudie Lobban, Hui-Nam Pak, Tatjana Potpara, Luis C Saenz, Isabelle C Van Gelder, Paul Varosy, Chris P Gale, Nikolaos Dagres, ,

AIMS:To develop quality indicators (QIs) that may be used to evaluate the quality of care and outcomes for adults with atrial fibrillation (AF). METHODS AND RESULTS:We followed the ESC methodology for QI development. This methodology involved (i) the identification of the domains of AF care for the diagnosis and management ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2020, :]

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Clinical Characteristics and Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England

Muhammad Rashid, Jianhua Wu, Adam Timmis, Nick Curzen, Azfar Zaman, Sarah Clarke, James Nolan, Ahmad Shoiab, Mohamed Mohamed, Mark De Belder, John Deanfield, Chris Gale, Mamas Mamas,

Background: Patients with underlying cardiovascular disease and Coronavirus disease 2019 (COVID-19) infection are at increased risk of morbidity and mortality. However, there is limited information on management and outcomes of patients presenting with acute coronary syndrome (ACS) and concomitant COVID19 infection. Objectives: This multisource national analysis of live data from ... Read more >>

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Association of cardiac rehabilitation and health-related quality of life following acute myocardial infarction.

Ben Hurdus, Theresa Munyombwe, Tatendashe Bernadette Dondo, Suleman Aktaa, Gerrard Oliver, Marlous Hall, Patrick Doherty, Alistair S Hall, Chris P Gale,

OBJECTIVE:To study the association of cardiac rehabilitation and physical activity with temporal changes in health-related quality of life (HRQoL) following acute myocardial infarction (AMI). METHODS:Evaluation of the Methods and Management of Acute Coronary Events-3 is a nationwide longitudinal prospective cohort study of 4570 patients admitted with an AMI between 1 ... Read more >>

Heart (Heart (British Cardiac Society))
[2020, :]

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The cancer patient and cardiology.

José Luis Zamorano, Christer Gottfridsson, Riccardo Asteggiano, Dan Atar, Lina Badimon, Jeroen J Bax, Daniela Cardinale, Antonella Cardone, Elizabeth A M Feijen, Péter Ferdinandy, Teresa López-Fernández, Chris P Gale, John H Maduro, Javid Moslehi, Torbjørn Omland, Juan Carlos Plana Gomez, Jessica Scott, Thomas M Suter, Giorgio Minotti,

Advances in cancer treatments have improved clinical outcomes, leading to an increasing population of cancer survivors. However, this success is associated with high rates of short- and long-term cardiovascular (CV) toxicities. The number and variety of cancer drugs and CV toxicity types make long-term care a complex undertaking. This requires ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, :]

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Place and underlying cause of death during the COVID19 pandemic: retrospective cohort study of 3.5 million deaths in England and Wales, 2014 to 2020

Jianhua Wu, Marion Mafham, Mamas Mamas, Muhammad Rashid, Evangelos Kontopantelis, John Deanfield, Mark de Belder, Chris Gale,

Background The COVID-19 pandemic has resulted in a high death toll. We aimed to describe the place and cause of death during the COVID-19 pandemic. Methods This national death registry included all adult (aged ≥18 years) deaths in England and Wales between 1st January 2014 and 30th June 2020. Analyses ... Read more >>

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Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Severe Aortic Stenosis in England

Glen Martin, Nick Curzen, Andrew Goodwin, James Nolan, Lognathen Balacumaraswami, Peter Ludman, Evangelos Kontopantelis, Jianhua Wu, Chris Gale, Mark de Belder, Mamas Mamas,

Background Aortic stenosis requires timely treatment with either surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). This study aimed to investigate the indirect impact of COVID-19 on national SAVR and TAVR activity and outcomes. Methods The UK TAVR Registry and the National Adult Cardiac Surgery Audit were ... Read more >>

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Research priorities for pregnancy hypertension: a UK priority setting partnership with the James Lind Alliance.

Alison Ho, Louise Webster, Liza Bowen, Fiona Creighton, Sarah Findlay, Chris Gale, Marcus Green, Toto Gronlund, Laura A Magee, Richard J McManus, Hiten D Mistry, Gemma Singleton, Jim Thornton, Rebecca Whybrow, Lucy Chappell,

OBJECTIVES:To identify research priorities for hypertensive disorders of pregnancy from individuals with lived experience and healthcare professionals. DESIGN:Prospective surveys and consensus meetings using principles outlined by the James Lind Alliance. SETTING:UK. METHODS:A steering group was established and 'uncertainties' were gathered using an online survey and literature search. An interim online ... Read more >>

BMJ Open (BMJ open)
[2020, 10(7):e036347]

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Regional differences in ST-segment-elevation myocardial infarction care and outcome: a call for multi-national cardiovascular registries.

Suleman Aktaa, Chris P Gale,

Eur Heart J Qual Care Clin Outcomes (European heart journal. Quality of care & clinical outcomes)
[2020, :]

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Gastric residual volume measurement in British neonatal intensive care units: a survey of practice.

Jon Dorling, Lyvonne Tume, Barbara Arch, Kerry Woolfall, Lynne Latten, Louise Roper, Elizabeth Deja, Nazima Pathan, Helen Eccleson, Helen Hickey, Michaela Brown, Anne Beissel, Izabela Andrzejewska, Frederic Valla, Chris Gale,

Objective:Despite little evidence, the practice of routine gastric residual volume (GRV) measurement to guide enteral feeding in neonatal units is widespread. Due to increased interest in this practice, and to examine trial feasibility, we aimed to determine enteral feeding and GRV measurement practices in British neonatal units. Design and setting:An ... Read more >>

BMJ Paediatr Open (BMJ paediatrics open)
[2020, 4(1):e000601]

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Surgical intervention for paediatric infusion-related extravasation injury: a systematic review.

Max Little, Sophie Dupré, Justin Conrad Rosen Wormald, Matthew Gardiner, Chris Gale, Abhilash Jain,

OBJECTIVES:This systematic review aims to assess the quality of literature supporting surgical interventions for paediatric extravasation injury and to determine whether there is sufficient evidence to support invasive techniques in children. METHODS:We performed a systematic review by searching Ovid MEDLINE and EMBASE as well as AMED, CINAHL, Cochrane Central Register ... Read more >>

BMJ Open (BMJ open)
[2020, 10(8):e034950]

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Trends of in-hospital and 30-day mortality after percutaneous coronary intervention in England before and after the COVID-19 era

Mohamed Mohamed, Tim Kinnaird, Nick Curzen, Peter Ludman, Jianhua Wu, Muhammad Rashid, Ahmad Shoaib, Mark de Belder, John Deanfield, Chris Gale, Mamas Mamas,

Objectives: To examine short-term primary causes of death after percutaneous coronary intervention (PCI) in a national cohort before and during COVID-19. Background: Public reporting of PCI outcomes is a performance metric and a requirement in many healthcare systems. There are inconsistent data on the causes of death after PCI, and ... Read more >>

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