Full Text Journal Articles by
Author Chiara Lonati

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Editorial Comment.

Chiara Lonati, Claudio Simeone, Marco Moschini,

J Urol (The Journal of urology)
[2021, :101097JU000000000000171501]

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Oncologic Surveillance for Variant Histology Bladder Cancer after Radical Cystectomy.

Alberto Martini, Luca Afferi, Stefania Zamboni, Julianne G Schultz, Chiara Lonati, Agostino Mattei, R Jeffrey Karnes, Matteo Soligo, Armando Stabile, Ettore Di Trapani, Ottavio De Cobelli, Giuseppe Simone, Claudio Simeone, Mario Alvarez-Maestro, Giorgio Gandaglia, Andrea Gallina, Renzo Colombo, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F Shariat, Marco Moschini,

<h4>Purpose</h4>Presently, major guidelines do not provide specific recommendations on oncologic surveillance for patients who harbor VH BCa at radical cystectomy. We aimed to create a personalized follow-up scheme that dynamically weighs OCM versus the risk of recurrence for VH BCa, and to compare it with a similar one for pUC.<h4>Methods</h4>Within ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001886]

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Accuracy of Transurethral Resection of the Bladder in Detecting Variant Histology of Bladder Cancer Compared with Radical Cystectomy.

Chiara Lonati, Philipp Baumeister, Paola Irene Ornaghi, Ettore Di Trapani, Ottavio De Cobelli, Michael Rink, Robert Jeffrey Karnes, Cédric Poyet, Giuseppe Simone, Luca Afferi, Andrea Necchi, Alberto Briganti, Francesco Montorsi, Wojciech Krajewski, Alessandro Antonelli, Maria Angela Cerruto, Stefania Zamboni, Claudio Simeone, Livio Mordasini, Agostino Mattei, Marco Moschini, ,

<h4>Background</h4>Correct identification of variant histologies (VHs) of bladder cancer (BCa) at transurethral resection of the bladder (TURB) could drive the subsequent treatment.<h4>Objective</h4>To evaluate the concordance in detecting VHs between TURB and radical cystectomy (RC) specimens in BCa patients.<h4>Design, setting, and participants</h4>We retrospectively analyzed 1881 BCa patients who underwent TURB and ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Single staff cystectomy in a low-volume center: Oncological outcomes and complications.

Philipp Baumeister, Davide Galioto, Marco Moschini, Chiara Lonati, Stefania Zamboni, Luca Afferi, Patrick Stucki, Hansjörg Danuser, Dirk Lehnick, Livio Mordasini, Agostino Mattei,

<h4>Introduction</h4>Radical cystectomy (RC) with bilateral pelvic lymph node dissection (PLND) is a complex surgical procedure, associated with substantial perioperative complications. Previous studies suggested reserving it to high-volume centers in order to improve oncological and perioperative outcomes. However, only limited data exist regarding low-volume centers with highly experienced surgeons. We aimed ... Read more >>

Can Urol Assoc J (Canadian Urological Association journal = Journal de l'Association des urologues du Canada)
[2021, :]

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Editorial Comment.

Chiara Lonati, Marco Moschini,

J Urol (The Journal of urology)
[2021, 206(1):21]

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Editorial Comment from Dr Lonati and Dr Moschini to Impact of preoperative sarcopenia and myosteatosis on prognosis after radical cystectomy in patients with bladder cancer.

Chiara Lonati, Marco Moschini,

Int J Urol (International journal of urology : official journal of the Japanese Urological Association)
[2021, :]

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The multifaceted spectrum of liver cirrhosis in older hospitalised patients: analysis of the REPOSI registry.

Antonio De Vincentis, Umberto Vespasiani-Gentilucci, Luisa Costanzo, Alessio Novella, Laura Cortesi, Alessandro Nobili, Pier Mannuccio Mannucci, Raffaele Antonelli Incalzi, ,

<h4>Background</h4>Knowledge on the main clinical and prognostic characteristics of older multimorbid subjects with liver cirrhosis (LC) admitted to acute medical wards is scarce.<h4>Objectives</h4>To estimate the prevalence of LC among older patients admitted to acute medical wards and to assess the main clinical characteristics of LC along with its association with ... Read more >>

Age Ageing (Age and ageing)
[2021, 50(2):498-504]

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A comparison of perioperative outcomes of laparoscopic versus open nephroureterectomy for upper tract urothelial carcinoma: a propensity score matching analysis.

Luca Afferi, Mohammad Abufaraj, Francesco Soria, David D'Andrea, Evanguelos Xylinas, Thomas Seisen, Morgan Roupret, Chiara Lonati, Alexandre De la Taille, Benoit Peyronnet, Ekaterina Laukhtina, Benjamin Pradere, Andrea Mari, Wojciech Krajewski, Mario Alvarez-Maestro, Eiji Kikuchi, Keisuke Shigeta, Piotr Chlosta, Francesco Montorsi, Alberto Briganti, Giuseppe Simone, Paola I Ornaghi, Maria Angela Cerruto, Alessandro Antonelli, Kazumasa Matsumoto, Pierre I Karakiewicz, Livio Mordasini, Agostino Mattei, Shahrokh F Shariat, Marco Moschini,

<h4>Background</h4>Radical nephroureterectomy (RNU) with the concomitant excision of the distal ureter and bladder cuff is the current standard of care for the treatment of muscle invasive and/or high-risk upper tract urothelial carcinoma (UTUC). In small uncontrolled studies, laparoscopic RNU has been suggested to be associated with better perioperative outcomes compared ... Read more >>

Minerva Urol Nefrol (Minerva urologica e nefrologica = The Italian journal of urology and nephrology)
[2021, :]

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Underdiagnosis and undertreatment of osteoporotic patients admitted in internal medicine wards in Italy between 2010 and 2016 (the REPOSI Register).

Jessica Pepe, Pasquale Agosti, Cristiana Cipriani, Mauro Tettamanti, Alessandro Nobili, Luciano Colangelo, Rachele Santori, Mirella Cilli, Salvatore Minisola, ,

<h4>Purpose</h4>To evaluate clinical features, treatments, and outcomes of osteoporotic patients admitted to internal medicine and geriatric wards compared with non-osteoporotic patients (REPOSI registry).<h4>Methods</h4>We studied 4714 patients hospitalized between 2010 and 2016. We reported age, sex, educational level, living status, comorbidities and drugs taken, Cumulative Illness Rating Scale (CIRS), Barthel Index, ... Read more >>

Endocrine (Endocrine)
[2021, 71(2):484-493]

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A thigh urinary fistula following radical prostatectomy and external beam radiation therapy for prostate cancer: a case report.

Stefania Zamboni, Chiara Lonati, Giuseppe Mirabella, Maria Furlan, Barbara Frittoli, Claudio Simeone,

Urinary fistula is a rare but severe complication which could occur after radiation therapy for prostate cancer (PCa). We describe the case of an inner thigh urinary fistula in a patient treated with radical prostatectomy and adjuvant radiation therapy for PCa. A 76-year-old man presented to the emergency room complaining ... Read more >>

Urol Case Rep (Urology case reports)
[2021, 36:101558]

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Pain and Frailty in Hospitalized Older Adults.

Ilaria Ardoino, Carlotta Franchi, Alessandro Nobili, Pier Mannuccio Mannucci, Oscar Corli, ,

<h4>Introduction</h4>Pain and frailty are prevalent conditions in the older population. Many chronic diseases are likely involved in their origin, and both have a negative impact on quality of life. However, few studies have analysed their association.<h4>Methods</h4>In light of this knowledge gap, 3577 acutely hospitalized patients 65 years or older enrolled in ... Read more >>

Pain Ther (Pain and therapy)
[2020, 9(2):727-740]

Cited: 2 times

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Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry.

Christiano Argano, Nicola Scichilone, Giuseppe Natoli, Alessandro Nobili, Gino Roberto Corazza, Pier Mannuccio Mannucci, Francesco Perticone, Salvatore Corrao, ,

Currently, chronic obstructive pulmonary disease (COPD) represents the fourth cause of death worldwide with significant economic burden. Comorbidities increase in number and severity with age and are identified as important determinants that influence the prognosis. In this observational study, we retrospectively analyzed data collected from the RePoSI register. We aimed ... Read more >>

Intern Emerg Med (Internal and emergency medicine)
[2021, 16(2):389-400]

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Comorbidities in idiopathic pulmonary fibrosis: an underestimated issue.

Antonella Caminati, Chiara Lonati, Roberto Cassandro, Davide Elia, Giuseppe Pelosi, Olga Torre, Maurizio Zompatori, Elisabetta Uslenghi, Sergio Harari,

Idiopathic pulmonary fibrosis (IPF) is a progressive and fibrosing lung disease with a poor prognosis. Between 60% and 70% of IPF patients die of IPF; the remaining causes of death may be due to comorbidities occurring in this ageing population. Interest in the role played by comorbidities in IPF has ... Read more >>

Eur Respir Rev (European respiratory review : an official journal of the European Respiratory Society)
[2019, 28(153):]

Cited: 7 times

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Patterns of infections in older patients acutely admitted to medical wards: data from the REPOSI register.

Raffaella Rossio, Ilaria Ardoino, Carlotta Franchi, Alessandro Nobili, Pier Mannuccio Mannucci, Flora Peyvandi, ,

Intern Emerg Med (Internal and emergency medicine)
[2019, 14(8):1347-1352]

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Pulmonary hypertension and chronic lung disease: where are we headed?

Davide Elia, Antonella Caminati, Maurizio Zompatori, Roberto Cassandro, Chiara Lonati, Francesca Luisi, Giuseppe Pelosi, Steeve Provencher, Sergio Harari,

Pulmonary hypertension related to chronic lung disease, mainly represented by COPD and idiopathic pulmonary fibrosis, is associated with a worse outcome when compared with patients only affected by parenchymal lung disease. At present, no therapies are available to reverse or slow down the pathological process of this condition and most ... Read more >>

Eur Respir Rev (European respiratory review : an official journal of the European Respiratory Society)
[2019, 28(153):]

Cited: 3 times

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Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients.

Franchi Carlotta, Rossio Raffaella, Ardoino Ilaria, Nobili Alessandro, Mannucci Pier Mannuccio, ,

Eur J Intern Med (European journal of internal medicine)
[2019, 68:e7-e11]

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Incremental prognostic value of global left atrial peak strain in women with new-onset gestational hypertension.

Andrea Sonaglioni, Chiara Lonati, Michele Lombardo, Elisabetta Rigamonti, Giulia Binda, Antonio Vincenti, Gian L Nicolosi, Stefano Bianchi, Sergio Harari, Claudio Anzà,

<h4>Background</h4>Left atrial strain and strain rate parameters, measured by bidimensional-speckle tracking echocardiography, have been proposed as predictors of atrial fibrillation, stroke, congestive heart failure and cardiovascular death. However, they have not yet been tested in hypertensive disorders of pregnancy. The aim of this study was to assess the prognostic role ... Read more >>

J Hypertens (Journal of hypertension)
[2019, 37(8):1668-1675]

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Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled Bronchodilators and Corticosteroids.

Marco Proietti, Pasquale Agosti, Chiara Lonati, Salvatore Corrao, Francesco Perticone, Pier Mannuccio Mannucci, Alessandro Nobili, Sergio Harari, ,

<h4>Objectives</h4>We aimed to analyze the prevalence and impact of COPD in older patients hospitalized in internal medicine or geriatric wards, and to investigate adherence to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, associated clinical factors, and outcomes.<h4>Design</h4>Data were obtained from REgistro POliterapie SIMI (REPOSI), a prospective multicenter ... Read more >>

J Am Med Dir Assoc (Journal of the American Medical Directors Association)
[2019, 20(10):1313-1317.e9]

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Need for Deprescribing in Hospital Elderly Patients Discharged with a Limited Life Expectancy: The REPOSI Study.

Luca Pasina, Barbara Brignolo Ottolini, Laura Cortesi, Mauro Tettamanti, Carlotta Franchi, Alessandra Marengoni, Pier Mannuccio Mannucci, Alessandro Nobili, ,

<h4>Objective</h4>Older people approaching the end of life are at a high risk for adverse drug reactions. Approaching the end of life should change the therapeutic aims, triggering a reduction in the number of drugs.The main aim of this study is to describe the preventive and symptomatic drug treatments prescribed to ... Read more >>

Med Princ Pract (Medical principles and practice : international journal of the Kuwait University, Health Science Centre)
[2019, 28(6):501-508]

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Polypharmacy in older people: lessons from 10 years of experience with the REPOSI register.

Pier Mannuccio Mannucci, Alessandro Nobili, Luca Pasina, ,

As a consequence of population aging, we have witnessed in internal medicine hospital wards a progressive shift from a population of in-patients relatively young and mainly affected by a single ailment to one of ever older and more and more complex patients with multiple chronic diseases, followed as out-patients by ... Read more >>

Intern Emerg Med (Internal and emergency medicine)
[2018, 13(8):1191-1200]

Cited: 8 times

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Nocturnal Blood Pressure Dipping is Abolished in Old-Elderly Hospitalized Patients.

Francesco Salvo, Chiara Lonati, Michele Berardi, Andrea Riccardo Errani, Carlo Lorenzo Muzzulini, Alberto Morganti,

<h4>Introduction</h4>During sleep there is reduction of blood pressure (BP) caused by a decrease of the sympathetic nervous tone. This nocturnal "dipping" phenomenon, assessable with ambulatory blood pressure monitoring (ABPM), is blunted with increasing age.<h4>Aim</h4>To assess the effect of hospitalization on night-time BP fall in old-elderly patients.<h4>Methods</h4>We analysed 78 ABPM of ... Read more >>

High Blood Press Cardiovasc Prev (High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension)
[2017, 24(4):413-417]

Cited: 1 time

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ABPM Induced Alarm Reaction: A Possible Cause of Overestimation of Daytime Blood Pressure Values Reduced By Treatment with Beta-Blockers.

Francesco Salvo, Chiara Lonati, Monica Albano, Paolo Fogliacco, Andrea Riccardo Errani, Cinzia Vallo, Michele Berardi, Vito Meinero, Carlo Lorenzo Muzzulini, Alberto Morganti,

<h4>Introduction</h4>Alarm reaction to clinical blood pressure (BP) measurement, defined white-coat effect (WCE), can cause overestimation of true BP values.<h4>Aim</h4>To assess whether ambulatory blood pressure monitoring (ABPM) can similarly affect BP values during the initial hours of recording.<h4>Methods</h4>In 420 ABPMs selected for a first systolic BP (SBP) reading at least 10 mmHg ... Read more >>

High Blood Press Cardiovasc Prev (High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension)
[2016, 23(3):255-258]

Cited: 1 time

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Association Between Lifestyle and Systemic Arterial Hypertension in Young Adults: A National, Survey-Based, Cross-Sectional Study.

Rosa Maria Bruno, Giacomo Pucci, Martina Rosticci, Laura Guarino, Chiara Guglielmo, Claudia Agabiti Rosei, Silvia Monticone, Alessandra Giavarini, Chiara Lonati, Camilla Torlasco, Massimiliano Fedecostante, Maria Virginia Manzi, Francesca Pezzutto, Marina Di Pilla, Nathan Artom, Allegra Battistoni, Giulia Pignatelli, Viola Sanga, Martino Francesco Pengo,

<h4>Introduction</h4>The prevalence of systemic arterial hypertension in young adults is increasing worldwide in association with modifiable risk factors.<h4>Aim</h4>To assess the prevalence of high blood pressure (BP) in young adults participating to a screening campaign during the World Hypertension Day (17/05/2014), and to determine the possible association with lifestyle factors.<h4>Methods</h4>493 individuals ... Read more >>

High Blood Press Cardiovasc Prev (High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension)
[2016, 23(1):31-40]

Cited: 11 times

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Hypovitaminosis D and organ damage in patients with arterial hypertension: a multicenter double blind randomised controlled trial of cholecalciferol supplementation (HYPODD) : study design, clinical procedures and treatment protocol.

Domenico Rendina, Renato Ippolito, Lanfranco D'Elia, Gilberta Giacchetti, Chiara Lonati, Fernando Gianfrancesco, Francesco Fallo, Andrea Rebellato, Carmelinda Ruggiero, Speranza Rubattu, Speranza Rubattu, Massimo Volpe, Luigi Gennari, Daniela Merlotti, Gian Carlo Isaia, Patrizia D'Amelio, Elena Spertino, Bruno Fabris, Leonardo A Sechi, Cristiana Catena, Andrea M Maresca, Vera Gessi, Andrea Dalbeni, Pasquale Strazzullo,

<h4>Introduction</h4>At this time, good quality randomized clinical trials assessing the effects of vitamin D supplementation on cardiometabolic outcomes are lacking in the international literature.<h4>Aim</h4>To fill this gap, the Working Group on Vitamin D and Cardiorenal Disorders established jointly by the Italian Society of Hypertension (SIIA) and the Forum in Bone ... Read more >>

High Blood Press Cardiovasc Prev (High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension)
[2015, 22(2):135-142]

Cited: 2 times

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Are the antagonists of the renin-angiotensin system also anticancer agents?

Chiara Lonati, Alberto Morganti,

The antagonists of the renin-angiotensin system (RAS) have gained increasing popularity in the last two decades due to their indisputable efficacy in a number of cardiovascular disorders, coupled with an unsurpassed tolerability. However some years ago a partial and non-predefined meta-analysis raised the possibility that angiotensin receptor antagonists in particular ... Read more >>

High Blood Press Cardiovasc Prev (High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension)
[2015, 22(2):99-102]

Cited: 1 time

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