Full Text Journal Articles by
Author Cheng Zhang

Advertisement

Find full text journal articles






Target-directed enzyme-free dual-amplification DNA circuit for rapid signal amplification.

Chao Xing, Ziyi Chen, Cheng Zhang, Jun Wang, Chunhua Lu,

Dynamic DNA circuits have shown promising potential for amplified biosensing and bioengineering applications at the molecular level. Here, an enzyme-free, single-step and rapid signal amplification DNA circuit was developed by integrating target-directed entropy-driven catalysis (EDC) and hybridization chain reaction (HCR) for analysis of nucleic acids and small molecules. The target ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(47):10770-10775]

Cited: 0 times

View full text PDF listing >>



"Dual-Key-and-Lock" dual drug carrier for dual mode imaging guided chemo-photothermal therapy.

Feng Tian, Bin Chi, Chen Xu, Caixue Lin, Zushun Xu, Andrew K Whittaker, Cheng Zhang, Ling Li, Jing Wang,

Drug resistance and side effects are the two main problems of chemotherapy. In order to address these big challenges, [email protected]<sub>2</sub>, which has the ability to co-deliver both the hydrophobic drug doxorubicin hydrochloride (DOX) and the hydrophilic drug ibuprofen (IBU), is constructed to achieve synergistic treatment. The drug-loaded nanoparticle consists of ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(22):6212-6224]

Cited: 0 times

View full text PDF listing >>



Advertisement

Cu-Catalysed synthesis of benzo[f]indole-2,4,9(3H)-triones by the reaction of 2-amino-1,4-napthoquinones with α-bromocarboxylates.

Fazhou Yang, Ziyan Liu, Hao Liu, Yu Shangguan, Hao Deng, Jiaxing Huang, Yumei Xiao, Hongchao Guo, Cheng Zhang,

A copper-catalysed cascade ester amidation/radical cyclization of 2-amino-1,4-naphthoquinones with α-bromocarboxylates to afford benzo[f]indole-2,4,9(3H)-triones is described, and the reaction has a broad substrate scope and the desired products are obtained in mostly moderate to good yields. Mechanism-probing experiments indicate that the otherwise challenging radical coupling reaction of α-bromocarboxylates with 2-amino-1,4-naphthoquinones is ... Read more >>

Org Biomol Chem (Organic & biomolecular chemistry)
[2020, 18(34):6724-6731]

Cited: 0 times

View full text PDF listing >>



Integration of a porous coordination network and black phosphorus nanosheets for improved photodynamic therapy of tumor.

Miao-Deng Liu, Yun Yu, Deng-Ke Guo, Shi-Bo Wang, Chu-Xin Li, Fan Gao, Cheng Zhang, Bo-Ru Xie, Zhenlin Zhong, Xian-Zheng Zhang,

Selectively attenuating the protection offered by heat shock protein 90 (HSP90), which is indispensable for the stabilization of the essential regulators of cell survival and works as a cell guardian under oxidative stress conditions, is a potential approach to improve the efficiency of cancer therapy. Here, we designed a biodegradable ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(16):8890-8897]

Cited: 0 times

View full text PDF listing >>



LKB1IP promotes pathological cardiac hypertrophy by targeting PTEN/Akt signalling pathway.

Mi Tian, Xiuxin Jiang, Xinyun Li, Jianmin Yang, Cheng Zhang, Wencheng Zhang,

Pathological cardiac hypertrophy represents a leading cause of morbidity and mortality worldwide. Liver kinase B1 interacting protein 1 (LKB1IP) was identified as the binding protein of tumour suppressor LKB1. However, the role of LKB1IP in the development of pathological cardiac hypertrophy has not been explored. The aim of this study ... Read more >>

J Cell Mol Med (Journal of cellular and molecular medicine)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Nano-sized composite improving the insulating performance of insulating paper using low-temperature plasmas.

Shilin Wu, Cheng Zhang, Chuansheng Zhang, Weixin Yu, Qing Yang, Tao Shao,

Nanostructured dielectric composite has been considered as a promising manner in improving the flashover performance of oil-paper which has been widely used in power systems. In this paper, plasma-enhanced chemical vapor deposition (PECVD) is used to deposit SiO2 on the ceramic fiber-reinforced insulating paper. Scanning electron microscope images show a ... Read more >>

Nanotechnology (Nanotechnology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Operando Studies of Iodine Species in an Advanced Oxidative Water Treatment Reactor

Ahmed Moustafa, Alex Evans, Simmon Hofstetter, Jenny Boutros, Parastoo Pourrezaei, Cheng Zhang, Laura Patterson-Fortin, Charles Laing, Carter Goertzen, Richard Smith, Kenneth Code, Ning Cheng, Peter Blanchard, Nathan Bettman, Raquibul Alam, Kerry McPhedran, Zohreh Fallah, Edward Roberts, Michael Gaultois,

We present an electrochemical advanced oxidation process (eAOP) reactor employing expanded graphite, potassium iodide (KI), and electrical current, which demonstrates an exceptionally high rate of inactivation of E. coli (6log reduction in viable cells) at low current density 0.6 mA/cm^2), with low contact time (5 minutes) and low concentration of ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Rational design of a lysosome-targeting and near-infrared absorbing Ru(II)-BODIPY conjugate for photodynamic therapy.

Liping Qiao, Jiangping Liu, Yunhong Han, Fangmian Wei, Xinxing Liao, Cheng Zhang, Lina Xie, Liangnian Ji, Hui Chao,

A Ru(ii)-BODIPY conjugate has been rationally designed and exhibits an intense absorption in the NIR region to boost lysosome-targeted PDT in vitro and in vivo. The advantages of Ru(ii) and BODIPY were successfully instilled into the conjugate to yield highly effective PDT efficacy against malignant melanoma A375 cells (PI = ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, :]

Cited: 0 times

View full text PDF listing >>



Nano-designed carbon monoxide donor SMA/CORM2 exhibits protective effect against acetaminophen induced liver injury through macrophage reprograming and promoting liver regeneration.

Bingdong Song, Cheng Zhang, Weirong Hu, Chunyu Guo, Zhengmei Xia, Wanxia Hu, Mingqiang Qin, Weiying Jiang, Jinwei Lv, Dexiang Xu, Shichen Zhang, Jun Fang,

Acetaminophen (APAP) induced liver injury is the most common drug-induced liver injury, accounting for the top cause of acute liver failure in the United State, however the therapeutic options for it is very limited. Excess generation of reactive oxygen species (ROS) and the subsequent inflammatory responses are the major factors ... Read more >>

J Control Release (Journal of controlled release : official journal of the Controlled Release Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers.

Xiangyu Li, Woonghee Kim, Muhammad Arif, Chunxia Gao, Andreas Hober, David Kotol, Linnéa Strandberg, Björn Forsström, Åsa Sivertsson, Per Oksvold, Hasan Turkez, Morten Grøtli, Yusuke Sato, Haruki Kume, Seishi Ogawa, Jan Boren, Jens Nielsen, Mathias Uhlen, Cheng Zhang, Adil Mardinoglu,

Pyruvate kinase muscle type (<i>PKM</i>) is a key enzyme in glycolysis and plays an important oncological role in cancer. However, the association of <i>PKM</i> expression and the survival outcome of patients with different cancers is controversial. We employed systems biology methods to reveal prognostic value and potential biological functions of ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(2):]

Cited: 0 times

View full text PDF listing >>



Oxidative stress activates NORAD expression by H3K27ac and promotes oxaliplatin resistance in gastric cancer by enhancing autophagy flux via targeting the miR-433-3p.

Jizhao Wang, Yuchen Sun, Xing Zhang, Hui Cai, Cheng Zhang, Hangying Qu, Lin Liu, Mingxin Zhang, Junke Fu, Jia Zhang, Jiansheng Wang, Guangjian Zhang,

Oxaliplatin resistance undermines its curative effects on cancer and usually leads to local recurrence. The oxidative stress induced DNA damage repair response is an important mechanism for inducing oxaliplatin resistance by activating autophagy. ELISA is used to detect target genes expression. TMT-based quantitative proteomic analysis was used to investigate the ... Read more >>

Cell Death Dis (Cell death & disease)
[2021, 12(1):90]

Cited: 0 times

View full text PDF listing >>



Spinal Canal Decompression for Stage III Kummell’s Disease With “Compressing the Posterior Wall of the Vertebral Body” Guided by Intraoperative Ultrasonography - a Preliminary Clinical Study

Guangqing Cao, Jidong Zhang, Cheng Zhang, Howard Ginsberg, Manuel Fuetsch, Jie Zhao, Chunzheng Gao, Dongjin Wu,

<h4>Background: </h4> There is a lot of controversy regarding the treatment of patients with stage III Kummell’s disease (KD). The purpose of this study is to determine feasibility, efficacy and safety of spinal canal decompression via “compressing the posterior wall of the vertebral body”, guided by real time intraoperative ultrasonography ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Plasmons in the van der Waals charge-density-wave material 2H-TaSe2.

Chaoyu Song, Xiang Yuan, Ce Huang, Shenyang Huang, Qiaoxia Xing, Chong Wang, Cheng Zhang, Yuangang Xie, Yuchen Lei, Fanjie Wang, Lei Mu, Jiasheng Zhang, Faxian Xiu, Hugen Yan,

Plasmons in two-dimensional (2D) materials beyond graphene have recently gained much attention. However, the experimental investigation is limited due to the lack of suitable materials. Here, we experimentally demonstrate localized plasmons in a correlated 2D charge-density-wave (CDW) material: 2H-TaSe<sub>2</sub>. The plasmon resonance can cover a broad spectral range from the ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):386]

Cited: 0 times

View full text PDF listing >>



Effects of Sevoflurane Exposure on Apoptosis and Cell Cycle of Peripheral Blood Lymphocytes, and Immunologic Function

zhimin ji, Wanjun Wu, Fan zhou, Junfang Hu, Qiuping Xu, Weibin Yang, Xueyong Peng, XInguo Wang, Cheng Zhang, Li Li,

<h4>Background: </h4> Waste anesthetic gases (WAGS) leaked from new-type halogenated inhalational anesthetics such as sevoflurane were reported to pose a risk for the health of operation room personnel. The effects of WAGS on peripheral blood lymphocytes remain yet controversial. Purpose: The present study was undertaken to examine whether occupational exposure ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Melatonin Alleviates Cardiac Dysfunction Via Increasing Sirt1-Mediated Beclin-1 Deacetylation and Autophagy During Sepsis.

Qiang-Zhong Pi, Xiao-Wen Wang, Zhao-Lei Jian, Dan Chen, Cheng Zhang, Qing-Chen Wu,

Cardiac dysfunction is a major cause leading to multiple organ failure in sepsis. Beclin-1-dependent autophagy has been evidenced to exert protective effects on hearts in sepsis. However, the mechanisms on how Beclin-1 and autophagy are regulated remains enigmatic. To explore the detailed mechanisms controlling Beclin-1-dependent autophagy in septic heart and ... Read more >>

Inflammation (Inflammation)
[2021, :]

Cited: 0 times

View full text PDF listing >>



IGLL5 expression is correlated with tumor-infiltrating immune cells in clear cell renal cell carcinoma.

Zhi-Nan Xia, Xing-Yuan Wang, Li-Cheng Cai, Wen-Gang Jian, Cheng Zhang,

RCCs (renal cell carcinomas) account for about 90% of renal tumors, and their major histological subtype is ccRCC (clear cell RCC). Increasing evidence has indicated that the TME (tumor microenvironment) plays a significant role in the occurrence and development of ccRCC. In the present study, we employed ESTIMATE and CIBERSORT ... Read more >>

FEBS Open Bio (FEBS open bio)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Parameterizing the Yellow River Delta tidal creek morphology using automated extraction from remote sensing images.

Zhaoning Gong, Kuinan Mou, Qiwei Wang, Huachang Qiu, Cheng Zhang, Demin Zhou,

The tidal creek is an important part of the intertidal zone, which maintains the balance between depositional processes and a given hydrodynamic environment. Much can be inferred about the development and evolution of a tidal creek by examining its morphometry characteristics; this information can also provide scientific decision support for ... Read more >>

Sci Total Environ (The Science of the total environment)
[2021, 769:144572]

Cited: 0 times

View full text PDF listing >>



Verbascoside Attenuates Acute Inflammatory Injury Caused by an Intracerebral Hemorrhage Through the Suppression of NLRP3.

Hongwei Zhou, Cheng Zhang, Changren Huang,

Intracerebral hemorrhage (ICH) is a devastating cerebrovascular disease with a high mortality rate affecting individuals worldwide. After ICH, persistent inflammation results in the death of brain cells, as well as the promotion of secondary brain injury. Verbascoside (VB), an active component in herbal medicine, possesses antioxidant, anti-inflammatory and neuroprotective properties. ... Read more >>

Neurochem Res (Neurochemical research)
[2021, :]

Cited: 0 times

View full text PDF listing >>



A comparative study on the NOx storage and reduction performance of Pt/Ni1Mg2Al1Ox and Pt/Mn1Mg2Al1Ox catalysts.

Cheng Zhang, Yanshan Gao, Naveed Altaf, Qiang Wang,

A series of Ni1Mg2Al1Ox, Mn1Mg2Al1Ox, 0.5Pt/Ni1Mg2Al1Ox and 0.5Pt/Mn1Mg2Al1Ox catalysts were carefully prepared and their NOx storage and reduction (NSR) performance including NOx oxidation efficiency (NOE), NOx storage capacity (NSC), NOx conversion rate (XNO), N2 selectivity (SN2), N2O selectivity (SN2O) and NH3 selectivity (SNH3), was systematically investigated. A SO2 resistance test ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2020, 49(13):3970-3980]

Cited: 0 times

View full text PDF listing >>



Randomized Trial of Aspirin Versus Warfarin After Transcatheter Aortic Valve Replacement in Low-Risk Patients.

Toby Rogers, Christian Shults, Rebecca Torguson, Corey Shea, Puja Parikh, Thomas Bilfinger, Thomas Cocke, Mariano E Brizzio, Robert Levitt, Chiwon Hahn, Nicholas Hanna, George Comas, Paul Mahoney, Joseph Newton, Maurice Buchbinder, Ricardo Moreno, Cheng Zhang, Paige Craig, Federico M Asch, Gaby Weissman, Hector M Garcia-Garcia, Itsik Ben-Dor, Lowell F Satler, Ron Waksman,

<h4>Background</h4>The optimal antithrombotic regimen after transcatheter aortic valve replacement remains unclear.<h4>Methods</h4>In this randomized open-label study, low-risk patients undergoing transfemoral transcatheter aortic valve replacement at 7 centers in the United States were randomized 1:1 to low-dose aspirin or warfarin plus low-dose aspirin for 30 days. Patients who could not be randomized ... Read more >>

Circ Cardiovasc Interv (Circulation. Cardiovascular interventions)
[2021, 14(1):e009983]

Cited: 0 times

View full text PDF listing >>



Decoding the single-cell landscape and intercellular crosstalk in the transplanted liver: a 4-dimension mouse model

Haitao Huang, Xueyou Zhang, Hui Chen, Shi Feng, Cheng Zhang, Ruihan Chen, Yimou Lin, Qinghua Ji, Qi Ling,

<h4>ABSTRACT</h4> Graft remodeling after transplantation maintains graft functionality and determines graft survival. However, a comprehensive understanding of cellular diversity and interplay during graft remodeling remains to be fully characterized. In this study, we established a well tolerant C57BL/6 to C57BL/6 orthotopic liver transplantation (LT) mice model and observed two stages ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Tandem autologous hematopoietic stem cell transplantation for treatment of adult T-cell lymphoblastic lymphoma: a multiple center prospective study in China.

Yao Liu, Jun Rao, Jiali Li, Qin Wen, Sanbin Wang, Shifeng Lou, Tonghua Yang, Bin Li, Lei Gao, Cheng Zhang, Peiyan Kong, Li Gao, Maihong Wang, Lidan Zhu, Xixi Xiang, Sha Zhou, Xue Liu, Xiangui Peng, Jiangfan Zhong, Xi Zhang,

T-cell lymphoblastic lymphoma (T-LBL) is a highly aggressive form of lymphoma with poor clinical outcomes and lacks of a standard treatment regimen. In this study, we assessed the safety and efficacy of tandem autologous hematopoietic stem cell transplantation (auto-HSCT) strategy for adult T-LBL and evaluated prognostic factors affecting survival. 181 ... Read more >>

Haematologica (Haematologica)
[2021, 106(1):163-172]

Cited: 1 time

View full text PDF listing >>



Conjugation-broken thiophene-based electropolymerized polymers with well-defined structures: effect of conjugation lengths on electrochromic properties.

Ling Zhang, Feifei Luo, Weijun Li, Shuanma Yan, Zhangxin Chen, Ruiyang Zhao, Ning Ren, Yizhao Wu, Yuliang Chen, Cheng Zhang,

A series of monomers containing tetraphenylsilane connected to different thiophenes such as thiophene, bithiophene and terthiophene were designed and synthesized and were further used to prepare the corresponding polymers via electrochemical polymerization (pSiTPTP, pSiTPBTP and pSiTPTTP). From the polymers, the effective conjugate elements were well defined as bithiophene, quaterthiophene and ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2019, 21(43):24092-24100]

Cited: 1 time

View full text PDF listing >>



CCR2 improves homing and engraftment of adipose-derived stem cells in dystrophic mice.

Liang Wang, Huan Li, Jinfu Lin, Ruojie He, Menglong Chen, Yu Zhang, Ziyu Liao, Cheng Zhang,

<h4>Background</h4>Dystrophinopathy, a common neuromuscular disorder caused by the absence of dystrophin, currently lacks effective treatments. Systemic transplantation of adipose-derived stem cells (ADSCs) is a promising treatment approach, but its low efficacy remains a challenge. Chemokine system-mediated stem cell homing plays a critical role in systemic transplantation. Here, we investigated whether ... Read more >>

Stem Cell Res Ther (Stem cell research & therapy)
[2021, 12(1):12]

Cited: 0 times

View full text PDF listing >>



Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors

XinZhuang Wang, Qiuyi Jiang, Cheng Zhang, Quan Yang, Lixiang Wang, Jian Zhang, Ligang Wang, Xin Chen, Xu Hou, Dayong Han, Jianing Wu, Shi Guang Zhao,

<h4>Background: </h4> Tumors are the second most common cause of death in humans worldwide, second only to cardiovascular and cerebrovascular diseases. Although methods and techniques for the treatment of tumors continue to improve, the effect is not satisfactory. These may lack effective therapeutic targets. This study aimed to evaluate the ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.0025 s