Full Text Journal Articles by
Author Charles A Herzog

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CKD Progression in Medicare Beneficiaries With Nonvalvular Atrial Fibrillation Treated With Apixaban Versus Warfarin.

James B Wetmore, Heng Yan, Charles A Herzog, Eric Weinhandl, Jorge L Reyes, Nicholas S Roetker,

<h4>Rationale & objectives</h4>Comparing kidney disease progression among patients treated with direct oral anticoagulants (DOACs) versus warfarin has not been well studied. We hypothesized that apixaban, compared with warfarin, would be associated with lower risks of progression of chronic kidney disease (CKD) and progression to incident kidney failure in patients with ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2021, :]

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Response by Wetmore et al to Letter Regarding Article, "Direct-Acting Oral Anticoagulants Versus Warfarin in Medicare Patients With Chronic Kidney Disease and Atrial Fibrillation".

James B Wetmore, Nicholas S Roetker, Charles A Herzog,

Stroke (Stroke)
[2020, 51(12):e363-e364]

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A Novel Radiofrequency Device to Monitor Changes in Pulmonary Fluid in Dialysis Patients.

Jeffrey J Connaire, Matthew L Sundermann, Ramu Perumal, Charles A Herzog,

<h4>Background and objectives</h4>Fluid monitoring is an important management strategy in patients with chronic kidney disease (CKD) and heart failure (HF). The µCor™ Heart Failure and Arrhythmia Management System uses a radiofrequency-based thoracic fluid index (TFI) to track pulmonary edema. During hemodialysis, the acute removal of fluid through ultrafiltration offers a ... Read more >>

Med Devices (Auckl) (Medical devices (Auckland, N.Z.))
[2020, 13:377-383]

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International consensus definitions of clinical trial outcomes for kidney failure: 2020.

Adeera Levin, Rajiv Agarwal, William G Herrington, Hiddo L Heerspink, Johannes F E Mann, Shahnaz Shahinfar, Katherine R Tuttle, Jo-Ann Donner, Vivekanand Jha, Masaomi Nangaku, Dick de Zeeuw, Meg J Jardine, Kenneth W Mahaffey, Aliza M Thompson, Mary Beaucage, Kate Chong, Glenda V Roberts, Duane Sunwold, Hans Vorster, Madeleine Warren, Sandrine Damster, Charu Malik, Vlado Perkovic, ,

Kidney failure is an important outcome for patients, clinicians, researchers, healthcare systems, payers, and regulators. However, no harmonized international consensus definitions of kidney failure and key surrogates of progression to kidney failure exist specifically for clinical trials. The International Society of Nephrology convened an international multi-stakeholder meeting to develop consensus ... Read more >>

Kidney Int (Kidney international)
[2020, 98(4):849-859]

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Acute hyperkalemia in the emergency department: a summary from a Kidney Disease: Improving Global Outcomes conference.

Gregor Lindner, Emmanuel A Burdmann, Catherine M Clase, Brenda R Hemmelgarn, Charles A Herzog, Jolanta Małyszko, Masahiko Nagahama, Roberto Pecoits-Filho, Zubaid Rafique, Patrick Rossignol, Adam J Singer,

Hyperkalemia is a common electrolyte disorder observed in the emergency department. It is often associated with underlying predisposing conditions, such as moderate or severe kidney disease, heart failure, diabetes mellitus, or significant tissue trauma. Additionally, medications, such as inhibitors of the renin-angiotensin-aldosterone system, potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs, succinylcholine, and ... Read more >>

Eur J Emerg Med (European journal of emergency medicine : official journal of the European Society for Emergency Medicine)
[2020, 27(5):329-337]

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Identifying critically important cardiovascular outcomes for trials in hemodialysis: an international survey with patients, caregivers and health professionals.

Emma O'Lone, Martin Howell, Andrea K Viecelli, Jonathan C Craig, Allison Tong, Benedicte Sautenet, William G Herrington, Charles A Herzog, Tazeen H Jafar, Meg Jardine, Vera Krane, Adeera Levin, Jolanta Malyszko, Michael V Rocco, Giovanni Strippoli, Marcello Tonelli, Angela Yee-Moon Wang, Christoph Wanner, Faiez Zannad, Wolfgang C Winkelmayer, David C Wheeler,

<h4>Background</h4>Cardiovascular disease (CVD) is a major contributor to morbidity and mortality in people on hemodialysis (HD). Cardiovascular outcomes are reported infrequently and inconsistently across trials in HD. This study aimed to identify the priorities of patients/caregivers and health professionals (HPs) for CVD outcomes to be incorporated into a core outcome ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2020, 35(10):1761-1769]

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Cardiac Imaging for Coronary Heart Disease Risk Stratification in Chronic Kidney Disease.

Vasken Dilsizian, Henry Gewirtz, Thomas H Marwick, Raymond Y Kwong, Paolo Raggi, Mouaz H Al-Mallah, Charles A Herzog,

Chronic kidney disease (CKD), defined as dysfunction of the glomerular filtration apparatus, is an independent risk factor for the development of coronary artery disease (CAD). Patients with CKD are at a substantially higher risk of cardiovascular mortality compared with the age- and sex-adjusted general population with normal kidney function. The ... Read more >>

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2020, :]

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Direct-Acting Oral Anticoagulants Versus Warfarin in Medicare Patients With Chronic Kidney Disease and Atrial Fibrillation.

James B Wetmore, Nicholas S Roetker, Heng Yan, Jorge L Reyes, Charles A Herzog,

BACKGROUND AND PURPOSE:The comparative effectiveness of direct-acting oral anticoagulants, compared with warfarin, for risks of stroke/systemic embolism, major bleeding, or death have not been studied in Medicare beneficiaries with atrial fibrillation and nondialysis-dependent chronic kidney disease. METHODS:Medicare data from 2011 to 2017 were used to identify patients with stages 3, ... Read more >>

Stroke (Stroke)
[2020, 51(8):2364-2373]

Cited: 1 time

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Outcomes Following Ischemic Stroke in Older Patients With CKD Stages 4 and 5: A Retrospective Cohort Study.

James B Wetmore, Charles A Herzog, Anne Sexter, David T Gilbertson, Jiannong Liu, Scott E Kasner,

<h4>Rationale & objective</h4>The associations between ischemic stroke and time to dialysis initiation and/or death in adults with late-stage chronic kidney disease (CKD) have not been explored. We sought to measure the rate and factors associated with stroke in CKD stages 4 and 5 (CKD4-5) and assess the association of stroke ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2020, 76(6):784-793]

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Establishing Core Cardiovascular Outcome Measures for Trials in Hemodialysis: Report of an International Consensus Workshop.

Emma O'Lone, Andrea K Viecelli, Jonathan C Craig, Allison Tong, Benedicte Sautenet, William G Herrington, Charles A Herzog, Tazeen H Jafar, Meg Jardine, Vera Krane, Adeera Levin, Jolanta Malyszko, Michael V Rocco, Giovanni Strippoli, Marcello Tonelli, Angela Yee Moon Wang, Christoph Wanner, Faiez Zannad, Wolfgang C Winkelmayer, David C Wheeler, ,

Cardiovascular disease (CVD) affects more than two-thirds of patients receiving hemodialysis and is the leading cause of death in this population, yet CVD outcomes are infrequently and inconsistently reported in trials in patients receiving hemodialysis. As part of the Standardised Outcomes in Nephrology-Haemodialysis (SONG-HD) initiative, we convened a consensus workshop ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2020, 76(1):109-120]

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Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.

Marlies Ostermann, Rinaldo Bellomo, Emmanuel A Burdmann, Kent Doi, Zoltan H Endre, Stuart L Goldstein, Sandra L Kane-Gill, Kathleen D Liu, John R Prowle, Andrew D Shaw, Nattachai Srisawat, Michael Cheung, Michel Jadoul, Wolfgang C Winkelmayer, John A Kellum, ,

In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). The guideline was derived from evidence available through February 2011. Since then, new evidence has emerged that has important implications for clinical practice in diagnosing and managing AKI. In ... Read more >>

Kidney Int (Kidney international)
[2020, 98(2):294-309]

Cited: 2 times

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Management of Coronary Disease in Patients with Advanced Kidney Disease.

Sripal Bangalore, David J Maron, Sean M O'Brien, Jerome L Fleg, Evgeny I Kretov, Carlo Briguori, Upendra Kaul, Harmony R Reynolds, Tomasz Mazurek, Mandeep S Sidhu, Jeffrey S Berger, Roy O Mathew, Olga Bockeria, Samuel Broderick, Radoslaw Pracon, Charles A Herzog, Zhen Huang, Gregg W Stone, William E Boden, Jonathan D Newman, Ziad A Ali, Daniel B Mark, John A Spertus, Karen P Alexander, Bernard R Chaitman, Glenn M Chertow, Judith S Hochman, ,

<h4>Background</h4>Clinical trials that have assessed the effect of revascularization in patients with stable coronary disease have routinely excluded those with advanced chronic kidney disease.<h4>Methods</h4>We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an initial invasive strategy consisting of ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(17):1608-1618]

Cited: 8 times

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Chronic kidney disease and valvular heart disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Thomas H Marwick, Kerstin Amann, Sripal Bangalore, João L Cavalcante, David M Charytan, Jonathan C Craig, John S Gill, Mark A Hlatky, Alan G Jardine, Ulf Landmesser, L Kristin Newby, Charles A Herzog, Michael Cheung, David C Wheeler, Wolfgang C Winkelmayer, Mark J Sarnak, ,

Chronic kidney disease (CKD) is a major risk factor for valvular heart disease (VHD). Mitral annular and aortic valve calcifications are highly prevalent in CKD patients and commonly lead to valvular stenosis and regurgitation, as well as complications including conduction system abnormalities and endocarditis. VHD, especially mitral regurgitation and aortic ... Read more >>

Kidney Int (Kidney international)
[2019, 96(4):836-849]

Cited: 1 time

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Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Catherine M Clase, Juan-Jesus Carrero, David H Ellison, Morgan E Grams, Brenda R Hemmelgarn, Meg J Jardine, Csaba P Kovesdy, Gregory A Kline, Gregor Lindner, Gregorio T Obrador, Biff F Palmer, Michael Cheung, David C Wheeler, Wolfgang C Winkelmayer, Roberto Pecoits-Filho, ,

Potassium disorders are common in patients with kidney disease, particularly in patients with tubular disorders and low glomerular filtration rate. A multidisciplinary group of researchers and clinicians met in October 2018 to identify evidence and address controversies in potassium management. The issues discussed encompassed our latest understanding of the regulation ... Read more >>

Kidney Int (Kidney international)
[2020, 97(1):42-61]

Cited: 6 times

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Chronic Kidney Disease and Coronary Artery Disease: JACC State-of-the-Art Review.

Mark J Sarnak, Kerstin Amann, Sripal Bangalore, João L Cavalcante, David M Charytan, Jonathan C Craig, John S Gill, Mark A Hlatky, Alan G Jardine, Ulf Landmesser, L Kristin Newby, Charles A Herzog, Michael Cheung, David C Wheeler, Wolfgang C Winkelmayer, Thomas H Marwick, ,

Chronic kidney disease (CKD) is a major risk factor for coronary artery disease (CAD). As well as their high prevalence of traditional CAD risk factors, such as diabetes and hypertension, persons with CKD are also exposed to other nontraditional, uremia-related cardiovascular disease risk factors, including inflammation, oxidative stress, and abnormal ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2019, 74(14):1823-1838]

Cited: 5 times

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Comparative Effectiveness of Medical Therapy, Percutaneous Revascularization, and Surgical Coronary Revascularization in Cardiovascular Risk Subgroups of Patients With CKD: A Retrospective Cohort Study of Medicare Beneficiaries.

David M Charytan, Tanya Natwick, Craig A Solid, Shuling Li, Tingting Gong, Charles A Herzog,

RATIONALE & OBJECTIVE:Prior studies suggesting that medical therapy is inferior to percutaneous (percutaneous coronary intervention [PCI]) or surgical (coronary artery bypass grafting [CABG]) coronary revascularization in chronic kidney disease (CKD) have not adequately considered medication optimization or baseline cardiovascular risk and have infrequently evaluated progression to kidney failure. We compared, ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2019, 74(4):463-473]

Cited: 1 time

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Congestive Heart Failure and Chronic Kidney Disease: The CardioRenal/NephroCardiology Connection.

Charles A Herzog,

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2019, 73(21):2701-2704]

Cited: 0 times

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Heart failure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Andrew A House, Christoph Wanner, Mark J Sarnak, Ileana L Piña, Christopher W McIntyre, Paul Komenda, Bertram L Kasiske, Anita Deswal, Christopher R deFilippi, John G F Cleland, Stefan D Anker, Charles A Herzog, Michael Cheung, David C Wheeler, Wolfgang C Winkelmayer, Peter A McCullough, ,

The incidence and prevalence of heart failure (HF) and chronic kidney disease (CKD) are increasing, and as such a better understanding of the interface between both conditions is imperative for developing optimal strategies for their detection, prevention, diagnosis, and management. To this end, Kidney Disease: Improving Global Outcomes (KDIGO) convened ... Read more >>

Kidney Int (Kidney international)
[2019, 95(6):1304-1317]

Cited: 6 times

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Canadian-Australasian Randomised trial of screening kidney transplant candidates for coronary artery disease-A trial protocol for the CARSK study.

Tracey Ying, Jagbir Gill, Angela Webster, S Joseph Kim, Rachael Morton, Scott W Klarenbach, Patrick Kelly, Timothy Ramsay, Gregory A Knoll, Helen Pilmore, Gillian Hughes, Charles A Herzog, Steven Chadban, John S Gill,

Transplantation is the preferred treatment for patients with kidney failure, but the need exceeds the supply of transplantable kidneys, and patients routinely wait >5 years on dialysis for a transplant. Coronary artery disease (CAD) is common in kidney failure and can exclude patients from transplantation or result in death before or ... Read more >>

Am Heart J (American heart journal)
[2019, 214:175-183]

Cited: 1 time

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Prophylactic Use of Implantable Cardioverter-Defibrillators in the Prevention of Sudden Cardiac Death in Dialysis Patients.

J Wouter Jukema, Rohit J Timal, Joris I Rotmans, Liselotte C R Hensen, Maurits S Buiten, Mihaly K de Bie, Hein Putter, Aeilko H Zwinderman, Lieselot van Erven, M Jacqueline Krol-van Straaten, Nienke Hommes, Bas Gabreëls, Wim van Dorp, Bastiaan van Dam, Charles A Herzog, Martin J Schalij, Ton J Rabelink, ,

BACKGROUND:Patients with end-stage renal disease who are undergoing dialysis are reported to be at high risk of sudden cardiac death (SCD), and to date, no therapy has been shown to be effective in reducing this risk. The feasibility and value of prophylactic implantable cardioverter-defibrillator (ICD) implantation to prevent SCD is ... Read more >>

Circulation (Circulation)
[2019, 139(23):2628-2638]

Cited: 3 times

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Relationship between dialytic parameters and reviewer confirmed arrhythmias in hemodialysis patients in the monitoring in dialysis study.

James A Tumlin, Prabir Roy-Chaudhury, Bruce A Koplan, Alexandru I Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M Charytan, ,

BACKGROUND:Hemodialysis patients have high rates of sudden death, but relationships between serum electrolytes, the dialysis prescription, and intra-dialytic shifts in fluid and electrolyte with arrhythmia are uncertain. METHODS:We analyzed sixty-six hemodialysis patients who underwent loop recorder implantation with continuous electrocardiographic monitoring, weekly to bi-weekly testing of pre- and post-dialysis electrolytes, ... Read more >>

BMC Nephrol (BMC nephrology)
[2019, 20(1):80]

Cited: 1 time

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Cardiovascular events and death after myocardial infarction or ischemic stroke in an older Medicare population.

Suying Li, Yi Peng, Xinyue Wang, Yi Qian, Pin Xiang, Sally W Wade, Haifeng Guo, J Antonio G Lopez, Charles A Herzog, Yehuda Handelsman,

<h4>Background</h4>Survivors of myocardial infarction (MI) or ischemic stroke (IS) are at high risk for subsequent cardiovascular events.<h4>Hypothesis</h4>Older patients with prior MI or IS are at risk for recurrent cardiovascular events, and comorbidities such as diabetes may increase this risk.<h4>Methods</h4>Two cohorts were studied in a retrospective Medicare 20% random sample-a 2008 ... Read more >>

Clin Cardiol (Clinical cardiology)
[2019, 42(3):391-399]

Cited: 4 times

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Excess Deaths Attributable to Influenza-Like Illness in the ESRD Population.

David T Gilbertson, Kenneth J Rothman, Glenn M Chertow, Brian D Bradbury, M Alan Brookhart, Jiannong Liu, Wolfgang C Winkelmayer, Til Stürmer, Keri L Monda, Charles A Herzog, Akhtar Ashfaq, Allan J Collins, James B Wetmore,

BACKGROUND:Morbidity and mortality vary seasonally. Timing and severity of influenza seasons contribute to those patterns, especially among vulnerable populations such as patients with ESRD. However, the extent to which influenza-like illness (ILI), a syndrome comprising a range of potentially serious respiratory tract infections, contributes to mortality in patients with ESRD ... Read more >>

J Am Soc Nephrol (Journal of the American Society of Nephrology : JASN)
[2019, 30(2):346-353]

Cited: 5 times

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Temporal Trends in Utilization of Cardiac Therapies and Outcomes for Myocardial Infarction by Degree of Chronic Kidney Disease: A Report From the NCDR Chest Pain-MI Registry.

Akshay Bagai, Di Lu, Joseph Lucas, Abhinav Goyal, Charles A Herzog, Tracy Y Wang, Shaun G Goodman, Matthew T Roe,

Background We sought to determine temporal trends in use of evidence-based therapies and clinical outcomes among myocardial infarction ( MI) patients with chronic kidney disease ( CKD ). Methods and Results MI patients from the NCDR (National Cardiovascular Data Registry) Chest Pain- MI Registry between January 2007 and December 2015 ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2018, 7(24):e010394]

Cited: 1 time

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Flow convergence visualized in mitral regurgitation with spontaneous echo contrast.

Aaron A H Smith, Michael Megaly, Melissa Madsen, Amy Waska, Bradley A Bart, Charles A Herzog,

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2019, 35(3):439-440]

Cited: 0 times

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