Full Text Journal Articles by
Author Chao Yu

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DCBLD2 regulates vascular hyperplasia by modulating the platelet derived growth factor receptor-β endocytosis through Caveolin-1 in vascular smooth muscle cells.

Shuai Wang, Xiaoning Liu, Zeqi Meng, Qi Feng, Yanling Lin, Honglin Niu, Chao Yu, Yanhong Zong, Lingling Guo, Weiwei Yang, Yuehua Ma, Wenjun Zhang, Chenyang Li, Yunran Yang, Wenjuan Wang, Xurui Gao, Yaxin Hu, Chao Liu, Lei Nie,

DCBLD2 is a neuropilin-like transmembrane protein that is up-regulated during arterial remodeling in humans, rats, and mice. Activation of PDGFR-β via PDGF triggers receptor phosphorylation and endocytosis. Subsequent activation of downstream signals leads to the stimulation of phenotypic conversion of VSMCs and arterial wall proliferation, which are common pathological changes ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2022, 36(9):e22488]

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Platelet count and clinical outcomes among ischemic stroke patients with endovascular thrombectomy in DIRECT-MT.

Tian Xu, Yu Zhou, Xinmin Wu, Hongzhi Zhou, Yunfeng Zhang, Chao Yu, Shuang He, Meiyun Lv, Pengfei Yang, Yongwei Zhang, Pengfei Xing, Lei Zhang, Xiaofei Ye, Ya Peng, Sheng Liu, Liyong Zhang, Qiyi Zhu, Kaifu Ke, Jianmin Liu, ,

<h4>Objectives</h4>The prognostic role of baseline platelet count (PLT) in acute ischemic stroke patients with large vessel occlusion undergoing endovascular thrombectomy is unclear. Whether PLT modifies alteplase treatment effect on clinical outcome in those patients is also uncertain.<h4>Methods</h4>We derived data from a multicenter randomized clinical trial (DIRECT-MT) comparing intravenous alteplase before ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2022, :]

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