Full Text Journal Articles by
Author Chao Xing

Advertisement

Find full text journal articles






Accelerated DNA tetrahedron-based molecular beacon for efficient microRNA imaging in living cells.

Chao Xing, Ziyi Chen, Yuhong Lin, Min Wang, Xin Xu, Junduan Dai, Jun Wang, Chunhua Lu,

Herein, we develop an accelerated DNA tetrahedron based molecular beacon for efficient detection and imaging of miRNA in living cells. Our study provides an improved strategy for fluorescence amplified RNA imaging in early clinical diagnosis. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(26):3251-3254]

Cited: 0 times

View full text PDF listing >>



Vagus nerve plays a pivotal role in CD4+ T cell differentiation during CVB3-induced murine acute myocarditis.

Li Yue-Chun, Xiao-Hong Gu, Ge Li-Sha, De-Pu Zhou, Chao Xing, Xiao-Ling Guo, Lu-Lu Pan, Shi-Yang Song, Li-Li Yu, Guang-Yi Chen, Jia-Feng Lin, Mao-Ping Chu,

Abnormalities in CD4<sup>+</sup> T cell (Th cell) differentiation play an important role in the pathogenesis of viral myocarditis (VMC). Our previous studies demonstrated that activation of the cholinergic anti-inflammatory pathway (CAP) alleviated the inflammatory response. In addition, we observed that right cervical vagotomy aggravates VMC by inhibiting CAP. However, the ... Read more >>

Virulence (Virulence)
[2021, 12(1):360-376]

Cited: 1 time

View full text PDF listing >>



Advertisement

Genome editing of Capsaspora owczarzaki suggests an ancestral function of the Hippo signaling effector YAP/TAZ/Yorkie in cytoskeletal dynamics but not proliferation

Jonathan Phillips, Maribel Santos, Mohammed Kanchwala, Chao Xing, Duojia Pan,

Many genes that function in animal development are present in the close unicellular relatives of animals, but little is known regarding the premetazoan function of these genes. Here, we develop techniques for genetic manipulation in the filasterean Capsaspora owczarzaki and use these tools to characterize the Capsaspora ortholog of the ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Tunable Graphene Oxide Nanofiltration Membrane for Effective Dye/Salt Separation and Desalination.

Chao Xing, Jing Han, Xin Pei, Yuting Zhang, Jing He, Rong Huang, Suhong Li, Changyu Liu, Chao Lai, Lingdi Shen, Ashok Kumar Nanjundan, Shanqing Zhang,

Effective dye separation and desalination are critical for the treatment of highly saline textile wastewater with dye mixtures. In this study, a graphene oxide (GO) membrane with a tunable interlayer distance (<i>d</i>) was fabricated to generate clean water <i>via</i> two-stage filtration, namely, the dye/salt separation and desalination stages. In the ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, 13(46):55339-55348]

Cited: 0 times

View full text PDF listing >>



STING mediates immune responses in the closest living relatives of animals.

Arielle Woznica, Ashwani Kumar, Carolyn R Sturge, Chao Xing, Nicole King, Julie K Pfeiffer,

Animals have evolved unique repertoires of innate immune genes and pathways that provide their first line of defense against pathogens. To reconstruct the ancestry of animal innate immunity, we have developed the choanoflagellate <i>Monosiga brevicollis</i>, one of the closest living relatives of animals, as a model for studying mechanisms underlying ... Read more >>

Elife (eLife)
[2021, 10:]

Cited: 0 times

View full text PDF listing >>



Identification of a Putative Enhancer RNA for EGFR in Hyper-Accessible Regions in Esophageal Squamous Cell Carcinoma Cells by Analysis of Chromatin Accessibility Landscapes.

Sangyong Choi, Adwait Sathe, Ewy Mathé, Chao Xing, Zui Pan,

Abnormal genetic and epigenetic modifications play a key role in esophageal cancer. By Assay for Transposase-Accessible Chromatin by sequencing (ATAC-seq), this study compared chromatin accessibility landscapes among two esophageal squamous cell carcinoma (ESCC) cell lines, KYSE-30 and KYSE-150, and a non-cancerous esophageal epithelial cell line, HET-1A. Data showed that hyper-accessible regions ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:724687]

Cited: 0 times

View full text PDF listing >>



STAG2 promotes the myelination transcriptional program in oligodendrocytes

Ningyan Cheng, Mohammed Kanchwala, Bret Evers, Chao Xing, Hongtao Yu,

<h4>SUMMARY</h4> Cohesin folds chromosomes via DNA loop extrusion. Cohesin-mediated chromosome loops regulate transcription by shaping long-range enhancer-promoter interactions, among other mechanisms. Mutations of cohesin subunits and regulators cause human developmental diseases termed cohesinopathy. Vertebrate cohesin consists of SMC1, SMC3, RAD21, and either STAG1 or STAG2. To probe the physiological functions ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Recurrent urinary tract infection and estrogen shape the taxonomic ecology and functional potential of the postmenopausal urobiome

Michael Neugent, Ashwani Kumar, Neha Hulyalkar, Kevin Lutz, Vivian Nguyen, Jorge Fuentes, Cong Zhang, Amber Nguyen, Belle Sharon, Amy Kuprasertkul, Amanda Arute, Qiwei Li, Chao Xing, Vladimir Shulaev, Philippe Zimmern, Kelli Palmer, Nicole De Nisco,

Community-acquired urinary tract infection (UTI) is among the most common bacterial infections observed in humans. Postmenopausal women are a rapidly growing and underserved demographic group who are severely affected by rUTI with a >50% recurrence rate. In this population, rUTI can persist for years, reducing quality of life and imposing ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



"Don't eat me/eat me"-combined apoptotic body analogues for efficient targeted therapy of triple-negative breast cancer.

Kailong Zhang, Huanru Fu, Chao Xing, Yi Luo, Fangfang Cheng, Qiang Fu, Yujie Huang, Longxin Qiu,

For the purpose of efficient targeted therapies, suppressing phagocytosis by a mononuclear phagocyte system (MPS), enhancing the "active" targeted delivery, and meeting clinical production criteria are extremely critical for engineering strategies of novel drug delivery systems. Herein, we used a chemically-induced membrane blebbing and extrusion combined method to induce triple-negative ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2021, 9(40):8472-8479]

Cited: 0 times

View full text PDF listing >>



Assessment of Biosafety and Implantation Feasibility of Novel Phakic Refractive Lens

Shaohua Zhang, Chang Huang, Huamao Miao, Junyao Wu, Chao Xing, Zhaoxing Dai, Jianguo Sun,

<h4>Purpose: </h4> To investigate the biosafety and implantation feasibility of newly developed phakic refractive lens (PRL) in rabbit eyes. <h4>Methods: </h4>: The PRLs, including short PRL (S-PRL), large PRL (L-PRL), and large grooved PRL (LG-PRL), were prepared by molding liquid medical silicon. The in vitro cytotoxicity of the above PRLs ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Corrigendum: Rational Fabrication of Multiple Dimensional Assemblies from Tryptophan-Based Racemate.

Yaqian Zhang, Minggao Qin, Chao Xing, Changli Zhao, Xiaoqiu Dou, Chuanliang Feng,

Chemistry (Chemistry (Weinheim an der Bergstrasse, Germany))
[2021, 27(60):15013]

Cited: 0 times

View full text PDF listing >>



High precision measurement for the chamfered hole radius and spacing of a large-size workpiece based on binocular vision combined with plane dynamic adjustment.

Junhui Huang, Miaowei Qi, Zhao Wang, Chao Xing, Jianmin Gao,

A novel, to the best of our knowledge, hole radius and spacing measurement method is presented based on binocular vision combined with dynamic local plane for the large-size workpiece with plane feature. The novel method overcomes the problem of the ariable working distance and large location error of an abrupt ... Read more >>

Appl Opt (Applied optics)
[2021, 60(29):9232-9240]

Cited: 0 times

View full text PDF listing >>



Rational Fabrication of Multiple Dimensional Assemblies from Tryptophan-Based Racemate.

Yaqian Zhang, Minggao Qin, Chao Xing, Changli Zhao, Xiaoqiu Dou, Chuanliang Feng,

Fabricating structural complex assemblies from simple amino acid-based derivatives is attracting great research interests due to their easy accessibility and preparation. However, the morphological regulation of racemates (an equimolar mixture of enantiomers) were largely overlooked. In this work, through rational modulation of kinetic and thermodynamic parameters, we achieved multiple dimensional ... Read more >>

Chemistry (Chemistry (Weinheim an der Bergstrasse, Germany))
[2021, 27(60):14911-14920]

Cited: 0 times

View full text PDF listing >>



Identification and functional annotation of differentially expressed long noncoding RNAs in retinoblastoma.

Xiaofen Feng, Jian Gong, Qian Li, Chao Xing, Jiandong Pan, Ruitao Zou, Liya Zheng, Feng Chen,

Retinoblastoma (RB), the most common intraocular malignancy, typically occurs in pediatric patients under the age of 6 years. The present study aimed to explore the long noncoding RNA (lncRNA) expression profile in RB and identify novel lncRNA biomarkers to facilitate the investigation of molecular mechanisms of RB and improve clinical ... Read more >>

Exp Ther Med (Experimental and therapeutic medicine)
[2021, 22(6):1447]

Cited: 0 times

View full text PDF listing >>



Identification of Potential Biomarkers and Therapy Targets involved in Gastric Cancer Using Bioinformatics Analysis

YangYang Teng, Na Shan, GuangRong Lu, LeYi Ni, ZeJun Gao, Yao Shen, Sheng Xu, QinJian Wang, QingJi Ying, Jing Zhang, HeJie Yu, ZhanXiong Xue, Chao Xing, ZhenZhai Cai,

Gastric cancer remains one of the five major malignant tumors in the world, posing a great threat to public life and health. As gene sequencing technology develops, it is urgent to find out specific molecular markers for cancer therapy. In this study, datasets of GSE13911, GSE30727, GSE63089 and GSE118916 were ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



IncRNA LUCAT1 acts as a Potential Biomarker and Demonstrates Malignant Biological Behaviors in Gastric Cancer.

Yang-Yang Teng, He-Jie Yu, Le-Yi Ni, Guang-Rong Lu, Yue-Sheng Zhu, Ling-Ling Zhou, Jing Zhang, Zhan-Xiong Xue, Zhen-Zhai Cai, Chao Xing,

<h4>Background</h4>Gastric cancer (GC) remains the fourth-leading malignancy worldwide and has a high mortality rate. Accumulating evidence reveals that long noncoding RNAs (lncRNAs) play essential roles in tumorigenesis and metastasis and can be used as potential biomarkers for diagnosis and prognosis.<h4>Methods</h4>We downloaded gene expression profiles from the National Center of Biotechnology ... Read more >>

Clin Lab (Clinical laboratory)
[2021, 67(8):]

Cited: 0 times

View full text PDF listing >>



An electrochemical sensor based on enzyme-free recycling amplification for sensitive and specific detection of miRNAs from cancer cells.

Lili Jiang, Yuling Yang, Yuhong Lin, Ziyi Chen, Chao Xing, Chunhua Lu, Huanghao Yang, Shusheng Zhang,

MicroRNAs (miRNAs) are desirable targets for the diagnosis, prognosis and treatment of diverse human diseases. In this study, we developed a universal and enzyme-free signal amplification approach for the quick, sensitive and specific electrochemical detection of diverse miRNAs from tumor cells using a catalyzed hairpin assembly (CHA) and the DNA ... Read more >>

Analyst (The Analyst)
[2020, 145(9):3353-3358]

Cited: 0 times

View full text PDF listing >>



TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling

Sushama Sivakumar, Shutao Qi, Ningyan Cheng, Adwait Sathe, Mohammed Kanchwala, Ashwani Kumar, Bret Evers, Chao Xing, Hongtao Yu,

<h4>SUMMARY</h4> Aneuploidy, defective differentiation, and inactivation of the tumor suppressor TP53 all occur frequently during tumorigenesis. Here, we probe the potential links among these cancer traits by inactivating TP53 in human embryonic stem cells (hESCs). TP53 −/− hESCs exhibit increased proliferation rates, mitotic errors, and low-grade structural aneuploidy; produce poorly ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Monogenic and polygenic causes of low and extremely low LDL-C levels in patients referred to specialty lipid clinics: Genetics of low LDL-C.

Brandon Jakubowski, Yanqiu Shao, Catherine McNeal, Chao Xing, Zahid Ahmad,

<h4>Background</h4>In clinical setting, current standard-of-care does not include genetic testing for patients with low (<50 mg/dL) and extremely low (<20 mg/dL) levels of serum low-density lipoprotein-cholesterol (LDL-C).<h4>Objective</h4>We aimed identify the underlying molecular cause - both monogenic and polygenic - of low and extremely low LDL-C levels in a cohort of patients presenting ... Read more >>

J Clin Lipidol (Journal of clinical lipidology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease.

Fei Luo, Chao Xing, Sumeet K Asrani, Shili Li, Guosheng Liang, Helen H Hobbs, Jonathan C Cohen,

A missense variant in the cytoplasmic domain of the insulin receptor (INSR) was identified by exome sequencing in affected members of a four-generation family with fatty liver disease (FLD). The variant (rs766457461, c.4063T>C, p.Y1355H) results in the substitution of histidine for a tyrosine that undergoes autophosphorylation in response to insulin ... Read more >>

Mol Metab (Molecular metabolism)
[2021, 53:101299]

Cited: 0 times

View full text PDF listing >>



Ultrasensitive electrochemical detection of microRNA based on in-situ catalytic hairpin assembly actuated DNA tetrahedral interfacial probes.

Zhangcheng Fu, Tong Lv, Lili Jiang, Chao Xing, Chunhua Lu,

Selective and sensitive detection of microRNA is crucial for early diagnosis and pathogenesis of disease. Here, we established a novel electrochemical biosensor for simple and accurate analysis of the tumor biomarker microRNA-141, which was based on in-situ catalytic hairpin assembly (CHA) actuated DNA tetrahedral (DTN) interfacial probes. Two hairpin structures ... Read more >>

Talanta (Talanta)
[2021, 233:122600]

Cited: 0 times

View full text PDF listing >>



Biallelic variants in RNU12 cause CDAGS syndrome.

Chao Xing, Mohammed Kanchwala, Jonathan J Rios, Tommy Hyatt, Richard C Wang, An Tran, Irene Dougherty, Andrea Tovar-Garza, Christy Purnadi, Monique G Kumar, David Berk, Marwan Shinawi, Alan D Irvine, Mirna Toledo-Bahena, Nnenna G Agim, Donald A Glass,

CDAGS Syndrome is a rare congenital disorder characterized by Craniosynostosis, Delayed closure of the fontanelles, cranial defects, clavicular hypoplasia, Anal and Genitourinary malformations, and Skin manifestations. We performed whole exome and Sanger sequencing to identify the underlying molecular cause in five patients with CDAGS syndrome from four distinct families. Whole ... Read more >>

Hum Mutat (Human mutation)
[2021, 42(8):1042-1052]

Cited: 0 times

View full text PDF listing >>



Gaussian process regression for direct laser absorption spectroscopy in complex combustion environments.

Weitian Wang, Zhenhai Wang, Xing Chao,

Tunable diode laser absorption spectroscopy (TDLAS) has been proved to be a powerful diagnostic tool in combustion research. However, current methods for post-processing a large number of blended spectral lines are often inadequate both in terms of processing speed and accuracy. The present study verifies the application of Gaussian process ... Read more >>

Opt Express (Optics express)
[2021, 29(12):17926-17939]

Cited: 0 times

View full text PDF listing >>



Low-intensity, Long-wavelength Red Light Slows the Progression of Myopia in Children: an Eastern China-based Cohort

Lei Zhou, Chao Xing, Wei Qiang, Chaoqun Hua, Liyang Tong,

Myopia is prevalent worldwide, particularly in East and Southeast Asia. Recent studies have suggested that the spectral composition of ambient lighting influences refractive development, especially in humans. We aimed to determine the effect of 650-nm single-wavelength red light on the inhibition of myopia progression in children. In this retrospective cohort ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



STING mediates immune responses in the closest living relatives of animals

Arielle Woznica, Ashwani Kumar, Carolyn Sturge, Chao Xing, Nicole King, Julie Pfeiffer,

Animals have evolved unique repertoires of innate immune genes and pathways that provide their first line of defense against pathogens. To reconstruct the ancestry of animal innate immunity, we have developed the choanoflagellate Monosiga brevicollis , one of the closest living relatives of animals, as a model for studying mechanisms ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.3347 s