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Author Chao Wang

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Cyclo-γ-polyglutamic acid-coated dual-responsive nanomicelles loaded with doxorubicin for synergistic chemo-photodynamic therapy.

Chao Wang, Beilei Wang, Shuaijun Zou, Bo Wang, Guoyan Liu, Fuhai Zhang, Qianqian Wang, Qian He, Liming Zhang,

Nanodrug delivery systems have been used extensively to improve the tumor-targeting ability and reduce the side effects of anticancer drugs. In this study, nanomicelles responsive to dual stimuli were designed and developed as drug carriers for delivering doxorubicin (DOX). The hydrophobic group of the nanomicelles was composed of the photosensitizer ... Read more >>

Biomater Sci (Biomaterials science)
[2021, 9(17):5977-5987]

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A high-accuracy machine-learning water model for exploring water nanocluster structures.

Hao Zhou, Ya-Juan Feng, Chao Wang, Teng Huang, Yi-Rong Liu, Shuai Jiang, Chun-Yu Wang, Wei Huang,

Water, the most important molecule on the Earth, possesses many essential and unique physical properties that are far from completely understood, partly due to serious difficulties in identifying the precise microscopic structures of water. Hence, identifying the structures of water nanoclusters is a fundamental and challenging issue for studies on ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(28):12212-12222]

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The effect of lipid metabolism regulator anthocyanins from Aronia melanocarpa on 3T3-L1 preadipocytes and C57BL/6 mice via activating AMPK signaling and gut microbiota.

Chunping Chen, Ximing Yang, Siqi Liu, Mingyan Zhang, Chao Wang, Xinxiu Xia, Yuhang Lou, Hongyan Xu,

This study investigated lipid metabolism regulation by anthocyanins from Aronia melanocarpa (AAM) in 3T3-L1 preadipocytes and high fat diet (HFD) mice. Ultra-performance liquid chromatography/ion mobility quadrupole time-of-flight mass spectrometry analysis identified the constituents of AAM, which decreased lipid content and inflammation in 3T3-L1 cells without cytotoxicity. Meanwhile, taking normal diet ... Read more >>

Food Funct (Food & function)
[2021, 12(14):6254-6270]

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Ant-nest-like Cu2-x[email protected] with biomimetic channels boosts the cycling performance for lithium storage.

Wanshu Luo, Meng Cao, Hanqing Pan, Qingqing Wang, Yinglan Ma, Chao Wang, Ying Wang, Yingqiu Gu, Lei Zhang,

Controlling the microstructure and composition of electrodes is crucial to enhance their rate capability and cycling stability for lithium storage. Inspired by the highly interconnected network and good mechanical integrity of an ant-nest architecture, herein, a biomimetic strategy is proposed to enhance the electrochemical performance of Cu2-xSe. After facile carbonization ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2021, 50(24):8330-8337]

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A hierarchical structure of a Co0.85[email protected]/[email protected] yolk-double-shell polyhedron for long-term lithium storage.

Meng Cao, Hanqing Pan, Wanshu Luo, Qingqing Wang, Yinglan Ma, Ying Wang, Chao Wang,

Constructing nanostructures with multi-components and delicate architecture exhibits huge potential to improve the lithium storage performance of electrodes. Herein, we report a novel yolk-double-shell structure with complex chemical compositions. Starting with a core-shell structured [email protected] as a precursor via a simple selenization process, yolk-double-shell polyhedra that assembled by nanosized Co<sub>0.85</sub>[email protected] ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(15):7244-7251]

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A high-performance asymmetric supercapacitor-based (CuCo)Se2/GA cathode and FeSe2/GA anode with enhanced kinetics matching.

Zhen Tian, Zhenxin Zhao, Xiaomin Wang, Yanjun Chen, Dan Li, Yaoyao Linghu, Yongzhen Wang, Chao Wang,

The performance of asymmetric supercapacitors (ASCs) is limited by the poorly matched electrochemical kinetics of available electrode materials, which generally results in reduced energy density and inadequate voltage utilization. Herein, a porous conductive graphene aerogel (GA) scaffold was decorated with copper cobalt selenide ((CuCo)Se<sub>2</sub>) or iron selenide (FeSe<sub>2</sub>) to construct ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(13):6489-6498]

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Reversible room-temperature phosphorescence in response to light stimulation based on a photochromic copolymer.

Bingbing Ding, Hao Gao, Chao Wang, Xiang Ma,

In the field of intelligent luminescence materials, it is a great challenge to regulate organic room-temperature phosphorescence by light irradiation. Herein, benzothiadiazole was modified with viologen derivatives and copolymerized to achieve amorphous RTP emission. The photo-stimulated color change in both emission and absorption has a good reversibility after cycles of ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(25):3154-3157]

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Detection of ascorbic acid based on its quenching effect on luminol-artemisinin chemiluminescence.

Chao Wang, Mohamed Ibrahim Halawa, Baohua Lou, Wenyue Gao, Jianping Li, Guobao Xu,

We find that luminol can react with artemisinin (ART) to produce chemiluminescence (CL) in the absence of a catalyst and ascorbic acid (AA) can quench luminol-ART CL. Based on its efficient inhibition effect on luminol-ART CL, a new AA detection method is established. The calibration curve for the determination of ... Read more >>

Analyst (The Analyst)
[2021, 146(6):1981-1985]

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Correction to: Impact of Ipsilateral Supraclavicular Lymph Node Dissection (ISLND) for Breast Cancer Patients and a Nomogram for Predicting Ipsilateral Supraclavicular Pathological Complete Response (ispCR).

Minhao Lv, Juntao Li, Huihui Guo, Chao Wang, Peiqi Tian, Youzhao Ma, Xiuchun Chen, Suxia Luo,

Ann Surg Oncol (Annals of surgical oncology)
[2021, 28(Suppl 3):871]

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Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers.

Chao Wang, Yuelin Li, Zi Liu, Zeyu Wang, Zihan Liu, Shuai Man, Yujing Zhang, Kai Bao, Yingliang Wu, Qi Guan, Daiying Zuo, Weige Zhang,

A series of 1-aryl-5-(4-arylpiperazine-1-carbonyl)-1<i>H</i>-tetrazols as microtubule destabilizers were designed, synthesised and evaluated for anticancer activity. Based on bioisosterism, we introduced the tetrazole moiety containing the hydrogen-bond acceptors as B-ring of XRP44X analogues. The key intermediates ethyl 1-aryl-1<i>H</i>-tetrazole-5-carboxylates <b>10</b> can be simply and efficiently prepared <i>via</i> a microwave-assisted continuous operation process. ... Read more >>

J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2021, 36(1):549-560]

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Blocking hsa_circ_0074027 suppressed non-small cell lung cancer chemoresistance via the miR-379-5p/IGF1 axis.

Shizhen Zheng, Chao Wang, Hao Yan, Yuejun Du,

Cancer cell chemoresistance is the primary reason behind cancer treatment failure. Previous reports suggest that circular RNA (circRNA) hsa_circ_0074027 (HC0074027) is a crucial modulator of non-small cell lung cancer (NSCLC) disease progression. Herein, we delineated the underlying mechanism of HC0074027-regulated chemoresistance in NSCLC. We employed quantitative real-time polymerase chain reaction ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):8347-8357]

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Major Challenges and Recent Advances in Characterizing Biomass Thermochemical Reactions

Zhennan Han, Junrong Yue, Xi Zeng, Jian Yu, Fang Wang, Yu Guan, Xuejing Liu, Fu Ding, Liangliang Fu, Xin Jia, Xingfei Song, Chao Wang, Yanbin Cui, Lei Shi, Kangjun Wang, Raffaella Ocone, Dingrong Bai, Guangwen Xu,

Thermochemical conversions are pathways for the utilization of biomass to produce a variety of value-added energy and chemical products. For the development of novel thermochemical conversion technologies, an accurate understanding of the reaction performance and kinetics is essential. Given the diversity of the thermal analysis techniques, it is necessary to ... Read more >>

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[Corrigendum] Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats.

Minchun Chen, Mingming Wang, Qiong Yang, Min Wang, Zhipeng Wang, Yanrong Zhu, Yikai Zhang, Chao Wang, Yanyan Jia, Yuwen Li, Aidong Wen,

Subsequently to the publication of the above article, an interested reader drew to the authors' attention that the OGD + HYSA and OGD + HYSA + AKBA plots in Fig. 5B on p. 1507 appeared to share a similar patterning with respect to many of the data points. The authors have re-examined their original data and realize that ... Read more >>

Int J Mol Med (International journal of molecular medicine)
[2022, 49(1):]

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Response to the Comment on "Efficacy and Safety of Complete Mesocolic Excision in Patients With Colon Cancer: Three-year Results from a Prospective, Nonrandomized, Double-blind, Controlled Trial".

Zhidong Gao, Chao Wang, Kewei Jiang, Zhanlong Shen, Shan Wang, Yingjiang Ye,

Ann Surg (Annals of surgery)
[2021, 274(6):e789-e790]

Cited: 2 times

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Enzymatic deamination of the epigenetic nucleoside N6-methyladenosine regulates gene expression.

Zhuoran Jiang, Chao Wang, Zixin Wu, Kun Chen, Wei Yang, Hexiang Deng, Heng Song, Xiang Zhou,

N6-methyladenosine (m6A) modification is the most extensively studied epigenetic modification due to its crucial role in regulating an array of biological processes. Herein, Bsu06560, formerly annotated as an adenine deaminase derived from Bacillus subtilis 168, was recognized as the first enzyme capable of metabolizing the epigenetic nucleoside N6-methyladenosine. A model ... Read more >>

Nucleic Acids Res (Nucleic acids research)
[2021, :]

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Genetic alterations in gastric amphicrine carcinomas and comparison with gastric mixed neuroendocrine-non-neuroendocrine neoplasms.

Lin Sun, Chao Wang, Jingyi Zhang, Bing Shao, Shuai Zhao, Yuhong Guo, XiangChun Li, Yan Sun,

Gastric amphicrine carcinoma, in which endocrine and epithelial cell features are present within the same cells, is often confused with gastric mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN). In this study, we performed high-resolution copy number (CN) profiling and whole exome sequencing (WES) of formalin-fixed and paraffin-embedded (FFPE) tissues from eight gastric amphicrine ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2021, :]

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Qingluoyin granules protect against adjuvant-induced arthritis in rats via downregulating the CXCL12/CXCR4-NF-κB signalling pathway.

Min Si, Zheng Ma, Jie Zhang, Xinwei Li, Rui Li, Chao Wang, Huiyu Jia, Shengyong Luo,

<h4>Context</h4>Qingluoyin (QLY) is a traditional Chinese medicine (TCM) formula which has been used in treating human rheumatoid arthritis (RA) for years in China.<h4>Objective</h4>This study investigates the effect of QLY granules on adjuvant arthritis (AA) and the possible mechanism.<h4>Materials and methods</h4>Sprague-Dawley (SD) rats were injected with Complete Freund's adjuvant (CFA) to ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):1441-1451]

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Effects of heat stress on virus transmission and virus-mediated apoptosis in whitefly Bemisia tabaci.

Xin-Ru Wang, Yue Shao, Chao Wang, Yin-Quan Liu,

Tomato yellow leaf curl virus (TYLCV), a plant DNA virus of the genus Begomovirus, is transmitted by whiteflies of the Bemisia tabaci species complex in a persistent manner. Our previous study indicated that activation of the apoptosis pathway in whiteflies could facilitate TYLCV accumulation and transmission. Considering that temperature change ... Read more >>

Arch Insect Biochem Physiol (Archives of insect biochemistry and physiology)
[2021, :e21857]

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Injectable Erythrocyte Gel Loaded with Bulleyaconitine A for the Treatment of Rheumatoid Arthritis.

Hao Chen, Bo Tian, Xiyao Fang, Jinyu Bai, Qingle Ma, Yue Zhang, Jialu Xu, Beilei Wang, Qin Fan, Ziying Fei, Huaxing Dai, Huajian Shan, Xiang Gao, Qirong Dong, Chao Wang, Xiaozhong Zhou,

Rheumatoid arthritis (RA) is a systemic autoimmune disease with clinical manifestations including joint cartilage, synovitis, and bone damage. Here we developed an injectable erythrocyte gel loaded with Bulleyaconitine A (BLA) for the treatment of RA and demonstrated its anti-inflammatory effects <i>in vivo</i> and <i>in vitro</i>. <i>In vitro</i> experiments showed that ... Read more >>

ACS Biomater Sci Eng (ACS biomaterials science & engineering)
[2021, :]

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Roburic acid attenuates osteoclastogenesis and bone resorption by targeting RANKL-induced intracellular signaling pathways.

Gang Wang, Kai Chen, Chao Ma, Chao Wang, Delong Chen, Jianbo He, Yuhao Liu, Tao Jiang, Jinbo Yuan, Leilei Chen, Wei He, Jiake Xu,

Excessive activity of osteoclasts contributes to skeletal diseases such as osteoporosis and osteolysis. However, current drugs targeting osteoclast have various deficiencies, placing natural compounds as substitutions of great potential. Roburic acid (RA) is a triterpenoid exacted from Radix Gentianae Macrophyllae, which exhibits inhibitory effects on inflammation and oxidation. By employing ... Read more >>

J Cell Physiol (Journal of cellular physiology)
[2021, :]

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Molecular characterization, receptor binding property, and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls, and wild birds in eastern China.

Jing Guo, Yanwen Wang, Conghui Zhao, Xinxin Gao, Yaping Zhang, Jiqing Li, Mengjing Wang, Hong Zhang, Wenqiang Liu, Chao Wang, Yingju Xia, Lu Xu, Guimei He, Jinyan Shen, Xiaohong Sun, Wenting Wang, Xinyu Han, Xiaoxuan Zhang, Zhengyang Hou, Xinlin Jin, Na Peng, Yubao Li, Guohua Deng, Pengfei Cui, Qianyi Zhang, Xuyong Li, Hualan Chen,

H9N2 avian influenza viruses are widely prevalent in birds and pose an increasing threat to humans because of their enhanced virulence and transmissibility in mammals. Active surveillance on the prevalence and evolution of H9N2 viruses in different avian hosts will help develop eradication measures. We isolated 16 H9N2 viruses from ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):2098-2112]

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Response to the Comment on "Efficacy and Safety of Complete Mesocolic Excision in Patients With Colon Cancer: Three-year Results From a Prospective, Nonrandomized, Double-blind, Controlled Trial".

Zhidong Gao, Chao Wang, Zhuang Tao, Yingjiang Ye,

Ann Surg (Annals of surgery)
[2021, 274(6):e755-e756]

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Unusual structural transformation and luminescence response of magic-size silver(I) chalcogenide clusters via ligand-exchange.

Wei-Hong Wu, Hui-Min Zeng, Ze-Nan Yu, Chao Wang, Zhan-Guo Jiang, Cai-Hong Zhan,

Structural transformations of nanoclusters provide a platform to tune their properties and understand the fundamental science due to their intimate structure-property correlation. Here, we present an alkynyl ligand-exchange induced growth of atomically precise silver(I) clusters, which are particularly of interest because of their luminescence response at room temperature. SCXRD and ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, :]

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Enhanced selective copper precipitation by mechanochemically activated benzene tricarboxylic acid.

Qing Shi, Shanshan Yan, Chao Wang, Chaocheng Zeng, Huimin Hu, Mengfei Chen, Min Chen, Qiwu Zhang,

<b>Abstract</b>Toward the treatment of waste solution containing heavy metals, direct precipitation of the metal ions from an acidic solution without alkaline neutralization is still the greatest challenge. Based on the ligand properties of benzene tricarboxylic acid (BTC) to copper ions, a simple ball milling with 90 min at 400 rpm was used ... Read more >>

Environ Technol (Environmental technology)
[2021, :1-24]

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Integration of a Metal-Organic Framework Film with a Tubular Whispering-Gallery-Mode Microcavity for Effective CO2 Sensing.

Ye Kong, Zhe Zhao, Yunqi Wang, Shuo Yang, Gaoshan Huang, Yang Wang, Chang Liu, Chunyu You, Ji Tan, Chao Wang, Borui Xu, Jizhai Cui, Xuanyong Liu, Yongfeng Mei,

Carbon dioxide (CO<sub>2</sub>) sensing using an optical technique is of great importance in the environment and industrial emission monitoring. However, limited by the poor specific adsorption of gas molecules as well as insufficient coupling efficiency, there is still a long way to go toward realizing a highly sensitive optical CO<sub>2</sub> ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, :]

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