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Author Catia Cilloniz

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Promoting the use of social networks in pneumonia.

Catia Cillóniz, Leith Greenslade, Cristina Dominedò, Carolina Garcia-Vidal,

BackgroundPneumonia is a serious health concern, but it does not attract the attention it warrants. Perhaps this is due to a lack of understanding of the real extent of this infectious disease in the general population.MethodsA literature review was performed to assess the role of social networks as a means ... Read more >>

(Pneumonia)
[2020, 12:]

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Difficult to Treat Microorganisms in Patients Over 80 Years with Community-Acquired Pneumonia: The Prevalence of PES Pathogens.

Catia Cilloniz, Cristina Dominedo, Héctor José Peroni, Pierluigi Di Giannatale, Carolina Garcia-Vidal, Albert Gabarrus, Adamanthia Liapikou, Adrian Ceccato, Antoni Torres,

Eur. Respir. J. (The European respiratory journal)
[2020, :]

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Advances in molecular diagnostic tests for pneumonia.

Catia Cilloniz, Adamanthia Liapikou, Antoni Torres,

PURPOSE OF REVIEW:Pneumonia is the main global cause of sepsis, and has been associated with high morbidity and high short and long-term mortality rates. As it may be caused by a wide spectrum of microorganisms, microbial diagnosis is challenging and the choice of adequate therapy remains an important problem. This ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2020, 26(3):241-248]

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Promoting the use of social networks in pneumonia.

Catia Cillóniz, Leith Greenslade, Cristina Dominedò, Carolina Garcia-Vidal,

Background:Pneumonia is a serious health concern, but it does not attract the attention it warrants. Perhaps this is due to a lack of understanding of the real extent of this infectious disease in the general population. Methods:A literature review was performed to assess the role of social networks as a ... Read more >>

Pneumonia (Nathan) (Pneumonia (Nathan Qld.))
[2020, 12:3]

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Gender differences in community-acquired pneumonia.

Elena Barbagelata, Catia Cillóniz, Cristina Dominedò, Antoni Torres, Antonello Nicolini, Paolo Solidoro,

INTRODUCTION:Community-acquired pneumonia (CAP) is the most common type of lower respiratory tract infection and a major cause of morbidity and mortality in adults worldwide. Sex and gender play an active role in the incidence and outcomes of major infectious diseases, including CAP. EVIDENCE ACQUISITION:We searched the following electronic databases from ... Read more >>

Minerva Med. (Minerva medica)
[2020, 111(2):153-165]

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Are macrolides as effective as fluoroquinolones in Legionella pneumonia?: YES, but….

Antoni Torres, Catia Cillóniz,

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Epidemiology, etiology, and risk factors of bacterial pneumonia.

Antoni Torres, Catia Cillóniz,

Hospital-acquired pneumonia (HAP) is the second most common nosocomial infection after urinary tract infections. The incidence of HAP ranges from 5 to 15 cases per 1000 hospital admissions, and is a frequent problem in general wards (incidence ranging from 1.6 to 3.67 cases per 1000 admissions). ... Read more >>

(Clinical Management of Bacterial Pneumonia)
[0, :7-28]

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Community-acquired pneumonia in critically ill very old patients: a growing problem.

Catia Cillóniz, Cristina Dominedò, Juan M Pericàs, Diana Rodriguez-Hurtado, Antoni Torres,

Very old (aged ≥80 years) adults constitute an increasing proportion of the global population. Currently, this subgroup of patients represents an important percentage of patients admitted to the intensive care unit. Community-acquired pneumonia (CAP) frequently affects very old adults. However, there are no specific recommendations for the management of critically ill ... Read more >>

Eur Respir Rev (European respiratory review : an official journal of the European Respiratory Society)
[2020, 29(155):]

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Community-Acquired Pneumonia. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) Guidelines. 2020 Update.

Rosario Menéndez, Catia Cilloniz, Pedro Pablo España, Jordi Almirall, Ane Uranga, Raúl Méndez, David Rigau, Antoni Torres,

The guidelines for community-acquired pneumonia, last published in 2010, have been updated to provide recommendations based on a critical summary of the latest literature to help health professionals make the best decisions in the care of immunocompetent adult patients. The methodology was based on 6 PICO questions (on etiological studies, ... Read more >>

Arch. Bronconeumol. (Archivos de bronconeumologia)
[2020, 56 Suppl 1:1-10]

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Ceftaroline for severe community-acquired pneumonia: A real-world two-centre experience in Italy and Spain.

Matteo Bassetti, Alessandro Russo, Catia Cilloniz, Daniele Roberto Giacobbe, Antonio Vena, Rosanel Amaro, Elena Graziano, Alex Soriano, Antoni Torres,

BACKGROUND:Ceftaroline is one of latest additions to the armamentarium for treating community-acquired pneumonia (CAP). This study aimed to describe the outcome of severe CAP (SCAP) in a cohort of hospitalised patients treated with ceftaroline. METHODS:A retrospective, observational study of patients with SCAP treated with ceftaroline in two hospitals in Spain ... Read more >>

Int. J. Antimicrob. Agents (International Journal of Antimicrobial Agents)
[2020, 55(4):105921]

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Can Artificial Intelligence Improve the Management of Pneumonia.

Mariana Chumbita, Catia Cillóniz, Pedro Puerta-Alcalde, Estela Moreno-García, Gemma Sanjuan, Nicole Garcia-Pouton, Alex Soriano, Antoni Torres, Carolina Garcia-Vidal,

The use of artificial intelligence (AI) to support clinical medical decisions is a rather promising concept. There are two important factors that have driven these advances: the availability of data from electronic health records (EHR) and progress made in computational performance. These two concepts are interrelated with respect to complex ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(1):]

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Macrolide combination therapy for hospitalised CAP patients? An individualised approach supported by machine learning.

Carolina Garcia-Vidal, Catia Cillóniz, Antoni Torres,

Eur. Respir. J. (The European respiratory journal)
[2019, 54(6):]

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Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection.

Sudhir Venkatesan, Puja R Myles, Kirsty J Bolton, Stella G Muthuri, Tarig Al Khuwaitir, Ashish P Anovadiya, Eduardo Azziz-Baumgartner, Tahar Bajjou, Matteo Bassetti, Bojana Beovic, Barbara Bertisch, Isabelle Bonmarin, Robert Booy, Victor H Borja-Aburto, Heinz Burgmann, Bin Cao, Jordi Carratala, Tserendorj Chinbayar, Catia Cilloniz, Justin T Denholm, Samuel R Dominguez, Pericles A D Duarte, Gal Dubnov-Raz, Sergio Fanella, Zhancheng Gao, Patrick Gérardin, Maddalena Giannella, Sophie Gubbels, Jethro Herberg, Anjarath Lorena Higuera Iglesias, Peter H Hoeger, Xiao Yun Hu, Quazi T Islam, Mirela F Jiménez, Gerben Keijzers, Hossein Khalili, Gabriela Kusznierz, Ilija Kuzman, Eduard Langenegger, Kamran B Lankarani, Yee-Sin Leo, Romina P Libster, Rita Linko, Faris Madanat, Efstratios Maltezos, Abdullah Mamun, Toshie Manabe, Gokhan Metan, Auksė Mickiene, Dragan Mikić, Kristin G I Mohn, Maria E Oliva, Mehpare Ozkan, Dhruv Parekh, Mical Paul, Barbara A Rath, Samir Refaey, Alejandro H Rodríguez, Bunyamin Sertogullarindan, Joanna Skręt-Magierło, Ayper Somer, Ewa Talarek, Julian W Tang, Kelvin To, Dat Tran, Timothy M Uyeki, Wendy Vaudry, Tjasa Vidmar, Paul Zarogoulidis, , Jonathan S Nguyen-Van-Tam,

BACKGROUND:The effect of neuraminidase inhibitor (NAI) treatment on length of stay (LoS) in patients hospitalized with influenza is unclear. METHODS:We conducted a one-stage individual participant data (IPD) meta-analysis exploring the association between NAI treatment and LoS in patients hospitalized with 2009 influenza A(H1N1) virus (A[H1N1]pdm09) infection. Using mixed-effects negative binomial ... Read more >>

J. Infect. Dis. (The Journal of infectious diseases)
[2020, 221(3):356-366]

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Reply to Dr. Daniel Musher.

Catia Cilloniz, Antoni Torres,

J. Infect. Dis. (The Journal of infectious diseases)
[2019, :]

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An overview of guidelines for the management of hospital-acquired and ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria.

Catia Cillóniz, Cristina Dominedò, Antoni Torres,

PURPOSE OF REVIEW:Multidrug-resistant (MDR) Gram-negative pathogens in hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are associated with poor clinical outcomes. These pathogens represent a global threat with few therapeutic options. In this review, we discuss current guidelines for the empiric management of HAP/VAP caused by MDR Gram-negative pathogens. RECENT FINDINGS:The ... Read more >>

Curr. Opin. Infect. Dis. (Current opinion in infectious diseases)
[2019, 32(6):656-662]

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The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study.

Bertrand Guidet, Dylan W de Lange, Ariane Boumendil, Susannah Leaver, Ximena Watson, Carol Boulanger, Wojciech Szczeklik, Antonio Artigas, Alessandro Morandi, Finn Andersen, Tilemachos Zafeiridis, Christian Jung, Rui Moreno, Sten Walther, Sandra Oeyen, Joerg C Schefold, Maurizio Cecconi, Brian Marsh, Michael Joannidis, Yuriy Nalapko, Muhammed Elhadi, Jesper Fjølner, Hans Flaatten, ,

PURPOSE:Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival after ICU admission. The primary aim of this study was to describe the prevalence of frailty, cognition decline and ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(1):57-69]

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Emerging antibiotics for community-acquired pneumonia.

Adamantia Liapikou, Catia Cilloniz, Andrea Palomeque, Toni Torres,

Introduction: Community-acquired pneumonia is the most common infection leading to hospitalization and death in all age groups, especially in elderly populations. Increasing antibiotic resistance among the common bacterial pathogens associated with community-acquired pneumonia, especially Streptococcus pneumoniae and staphylococci, has made its empirical treatment increasingly problematic, highlighting the need for effective ... Read more >>

Expert Opin Emerg Drugs (Expert opinion on emerging drugs)
[2019, 24(4):221-231]

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A multicentre analysis of Nocardia pneumonia in Spain: 2010-2016.

Maria Ercibengoa, Jordi Càmara, Fe Tubau, Dolores García-Somoza, Alicia Galar, Pablo Martín-Rabadán, Mercedes Marin, Lourdes Mateu, Ignasi García-Olivé, Cristina Prat, Catia Cilloniz, Antonio Torres, Maria-Luisa Pedro-Botet, Carmen Ardanuy, Patricia Muñoz, Jose María Marimón,

OBJECTIVE:To analyse all cases of Nocardia pneumonia occurring between 2010 and 2016 in five Spanish hospitals. METHODS:This was a retrospective observational analysis of clinical and microbiological data collected from 55 cases of Nocardia pneumonia. RESULTS:There were one to 20 cases per hospital and six to nine cases per year. Chronic ... Read more >>

Int. J. Infect. Dis. (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2020, 90:161-166]

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Ceftobiprole for the treatment of pneumonia.

C Cillóniz, C Dominedò, C Garcia-Vidal, A Torres,

Ceftobiprole is a fifth-generation cephalosporin with potent antimicrobial activity against Gram positive and Gram-negative bacteria. It has been approved in major European countries for the treatment of community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP), excluding ventilator-associated pneumonia (VAP). Ceftobiprole is currently in a phase 3 clinical program for registration in ... Read more >>

Rev Esp Quimioter (Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia)
[2019, 32 Suppl 3:17-23]

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Effect of Corticosteroids on C-Reactive Protein in Patients with Severe Community-Acquired Pneumonia and High Inflammatory Response: The Effect of Lymphopenia.

Antoni Torres, Adrian Ceccato, Miquel Ferrer, Albert Gabarrus, Oriol Sibila, Catia Cilloniz, Raúl Mendez, Rosario Menendez, Jesus Bermejo-Martin, Michael S Niederman,

BACKGROUND:Lymphopenic patients with community-acquired pneumonia (CAP) have shown high mortality rates. Corticosteroids have immunomodulatory properties and regulate cytokine storm in CAP. However, it is not known whether their modulatory effect on cytokine secretion differs in lymphopenic and non-lymphopenic patients with CAP. Therefore, we aimed to test whether the presence of ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 8(9):]

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Pneumocystis pneumonia in the twenty-first century: HIV-infected versus HIV-uninfected patients.

Catia Cillóniz, Cristina Dominedò, Míriam J Álvarez-Martínez, Asunción Moreno, Felipe García, Antoni Torres, José M Miro,

Introduction: Pneumocystis pneumonia (PcP) has classically been described as a serious complication in patients infected with the human immunodeficiency virus (HIV). However, the emerging number of conditions associated with immunosuppression has led to its appearance in other patient populations. Areas covered: This article reviews the most recent publications on PcP ... Read more >>

Expert Rev Anti Infect Ther (Expert review of anti-infective therapy)
[2019, 17(10):787-801]

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Impact of Cefotaxime Non-susceptibility on the Clinical Outcomes of Bacteremic Pneumococcal Pneumonia

Catia Cilloniz, Cristina de la Calle, Crsitina Dominedò, Carolina Garcia-Vidal, Celia Cardozo, Albert Gabarrus, Francesc Marco, Antoni Torres, Alex Soriano,

Background: We aimed to analyze the impact of cefotaxime non-susceptibility on the 30-day mortality rate in patients receiving a third-generation cephalosporin for pneumococcal bacteremic pneumonia. Methods: We conducted a retrospective observational study of prospectively collected data from the Hospital Clinic of Barcelona. All adult patients with monomicrobial bacteremic pneumonia due ... Read more >>

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Ventilator-Associated Pneumonia and PaO2/FIO2 Diagnostic Accuracy: Changing the Paradigm?

Miquel Ferrer, Telma Sequeira, Catia Cilloniz, Cristina Dominedo, Gianluigi Li Bassi, Ignacio Martin-Loeches, Antoni Torres,

BACKGROUND:Ventilator-associated pneumonia (VAP) is associated to longer stay and poor outcomes. Lacking definitive diagnostic criteria, worsening gas exchange assessed by PaO2/FIO2 ≤ 240 in mmHg has been proposed as one of the diagnostic criteria for VAP. We aim to assess the adequacy of PaO2/FIO2 ≤ 240 to diagnose VAP. METHODS:Prospective ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 8(8):]

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Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia.

David Villafuerte, Stefano Aliberti, Nilam J Soni, Paola Faverio, Pedro J Marcos, Richard G Wunderink, Alejandro Rodriguez, Oriol Sibila, Francisco Sanz, Ignacio Martin-Loeches, Francesco Menzella, Luis F Reyes, Mateja Jankovic, Marc Spielmanns, Marcos I Restrepo, ,

BACKGROUND AND OBJECTIVE:Enterobacteriaceae (EB) spp. family is known to include potentially multidrug-resistant (MDR) microorganisms, and remains as an important cause of community-acquired pneumonia (CAP) associated with high mortality. The aim of this study was to determine the prevalence and specific risk factors associated with EB and MDR-EB in a cohort ... Read more >>

Respirology (Respirology (Carlton, Vic.))
[2020, 25(5):543-551]

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Impact of Cefotaxime Non-susceptibility on the Clinical Outcomes of Bacteremic Pneumococcal Pneumonia.

Catia Cillóniz, Cristina de la Calle, Cristina Dominedò, Carolina García-Vidal, Celia Cardozo, Albert Gabarrús, Francesc Marco, Antoni Torres, Alex Soriano,

BACKGROUND:We aimed to analyze the impact of cefotaxime non-susceptibility on the 30-day mortality rate in patients receiving a third-generation cephalosporin for pneumococcal bacteremic pneumonia. METHODS:We conducted a retrospective observational study of prospectively collected data from the Hospital Clinic of Barcelona. All adult patients with monomicrobial bacteremic pneumonia due to Streptococcus ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 8(8):]

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