Full Text Journal Articles by
Author Carmen Isache

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Rapidly progressive necrotizing cellulitis secondary to Candida tropicalis infection in an immunocompromised host.

Nithya Krishnan, Bijal Patel, William Palfrey, Carmen Isache,

The incidence of invasive fungal infection is increasing as the population of immunosuppressed patients grows. Many species that were previously thought to be benign are now known pathogens. The most commonly isolated organisms (>80 %) include Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. However, there are several new and emerging ... Read more >>

IDCases (IDCases)
[2020, 19:e00691]

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Clinical impact of a pharmacist-led antimicrobial stewardship initiative evaluating patients with Clostridioides difficile colitis.

Paige A Bishop, Carmen Isache, Yvette S McCarter, Carmen Smotherman, Shiva Gautam, Christopher A Jankowski,

Clostridioides difficile is the most common cause of healthcare-associated infection and gastroenteritis-associated death in the USA. Adherence to guideline recommendations for treatment of severe C. difficile infection (CDI) is associated with improved clinical success and reduced mortality. The purpose of this study was to determine whether implementation of a pharmacist-led ... Read more >>

J. Investig. Med. (Journal of investigative medicine : the official publication of the American Federation for Clinical Research)
[2020, 68(4):888-892]

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Multiple myeloma with extensive AL amyloidosis presenting as chronic diarrhoea.

William Kogler, Catarina Canha, Raafat Makary, Reeba Omman, Carmen Liliana Isache,

We present a 52-year-old man admitted to the hospital with diarrhoea and lower extremity weakness ongoing for the past 3 months. The patient was found to have malabsorptive diarrhoea, hypoproliferative anaemia and renal insufficiency with proteinuria. Extensive workup was performed including a bone marrow biopsy with 20% plasma cells, renal and ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(1):]

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Central nervous system nocardiosis masquerading as metastatic brain lesions.

Hamel Patel, Bijal Patel, Sonal Jadeja, Carmen Isache,

Nocardiosis is an uncommon infection, however it needs to be included in the differential diagnosis, especially in immunocompromised hosts. Central nervous system (CNS) nocardiosis, in particular, is an even rarer entity with a higher mortality. This is a case of CNS Nocardia infection with an atypical presentation that was initially ... Read more >>

IDCases (IDCases)
[2019, 18:e00652]

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Methicillin-resistant Staphylococcus aureus pericarditis causing cardiac tamponade.

Maedeh Ganji, Jose Ruiz, William Kogler, Joshua Lung, Jarelys Hernandez, Carmen Isache,

Community acquired methicillin-resistant Staphylococcus aureus (MRSA) is an organism that can cause life threatening injuries with 6 cases of purulent pericarditis secondary to MRSA being reported so far. We report a 66 year-old -female who presented to our hospital with a two-week history of worsening shortness of breath, associated with ... Read more >>

IDCases (IDCases)
[2019, 18:e00613]

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Methicillin-resistant Staphylococcus aureus (MRSA) sepsis complicated by warm autoimmune haemolytic anaemia secondary to antimicrobial therapy.

Jorge Verdecia, Jarelys Hernandez, Christopher Izzo, Elisa Sottile, Carmen Isache,

A 61-year-old Caucasian woman presented to the emergency room complaining of left-sided chest pain and altered mentation for 3 days. Her medical history included liver cirrhosis and coronary artery disease. On admission, she was found to have methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia. Due to a decline in mental status, a lumbar ... Read more >>

BMJ Case Rep (BMJ case reports)
[2019, 12(8):]

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Endocarditis caused by Stenotrophomonas maltophilia-A rare presentation of an emerging opportunistic pathogen.

William Kogler, Nancy Davison, Aaron Richardson, Fabiana Rollini, Carmen Isache,

First isolated in 1943, Stenotrophomonas maltophilia (S. maltophilia) has historically been of little significance as it was considered a pathogen of low virulence noted to rarely infect immunocompromised hosts. However, over the last 30 years the prevalence of infection caused by the organism has increased significantly. Bacterial endocarditis from S. ... Read more >>

IDCases (IDCases)
[2019, 17:e00556]

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Kaposi sarcoma with musculoskeletal manifestations in a well-controlled HIV patient.

Jorge Verdecia, Firas Warda, Kevin Rechcigl, Mladen Sokanovic, Carmen Isache,

We present here a case of relapsed HIV-related Kaposi Sarcoma (KS), manifesting as a plantar ulcer with underlying bone involvement in a patient with well-controlled HIV. Radiographic and magnetic resonance imaging of the patient's right foot showed bone destruction suggestive of osteomyelitis. However, when a bone biopsy was done, this ... Read more >>

IDCases (IDCases)
[2019, 17:e00571]

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Trivalvular infective endocarditis secondary to Granulicatella adiacens and Peptostreptococcus spp.

Jorge Verdecia, Kelia Vahdat, Carmen Isache,

We present a case of a 42-year-old Caucasian man that came to our facility complaining of dyspnea and subjective fevers and was found to have infective endocarditis. His blood cultures initially grew Peptostreptococcus spp and he was started on penicillin and gentamicin. Repeat blood cultures, drawn 48 h later, became positive ... Read more >>

IDCases (IDCases)
[2019, 17:e00545]

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A case of West Nile virus encephalitis accompanied by diabetic ketoacidosis and rhabdomyolysis.

Zachary Burden, Madeline Fasen, Benjamin L Judkins, Carmen Isache,

Introduction:We present here a case of West Nile Virus (WNV) encephalitis that initially presented with diabetic ketoacidosis and rhabdomyolysis. Case presentation:A 35-year-old male with no past medical history presented to the emergency department complaining of polydipsia, generalized weakness, lightheadedness, and visual disturbances of one week duration. He was found to ... Read more >>

IDCases (IDCases)
[2019, 15:e00505]

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A Challenging Diagnosis of Ascites: A Case Report of Peritoneal Tuberculosis.

Jose Ruiz, Maedeh Ganji, Catarina Canha, Carmen Isache,

Approximately 2 billion people, which is about one third of the world's population, are infected with tuberculosis (TB). Around 10% of infected people will develop active TB at one point in their lifetime. We present a rare case of a 68-year-old male who presented to the emergency department with a ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2018, 2018:8136476]

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Sarcoidosis presenting with facial swelling (Heerfordt syndrome).

Satish Maharaj, Megan Brown, Karan Seegobin, Carmen Isache,

Sarcoidosis is one of the "great masqueraders" of medicine and can present with atypical facial swelling. Imaging and biopsy confirm the diagnosis. ... Read more >>

Clin Case Rep (Clinical case reports)
[2018, 6(10):2023-2024]

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Thalamic bacterial abscess presenting with hemiparesis and expressive aphasia.

Jarelys M Hernandez Jimenez, Kelia Vahdat, Ivan A Serrano Santiago, Maria Del Mar Morales Hernandez, Carmen L Isache, Michael Sands,

Brain abscesses are relative rare in the developing world, with an incidence of 2% of all space occupying lesions. Deep-seated abscesses such as thalamic and basal ganglia abscesses are much rarer than abscesses in other locations of the brain, comprising 1.3-6% of all brain abscesses. These abscesses may present with ... Read more >>

IDCases (IDCases)
[2018, 13:e00417]

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Avascular necrosis: a growing concern for the HIV population.

Kevin R Green, Jarelys M Hernandez-Jimenez, Carmen Liliana Isache, Rafik Jacob,

A 33-year-old woman with history of HIV presented with 4 months of gradually progressing right hip pain and was found to have avascular necrosis (AVN) of both femoral heads. She had no other risk factors for AVN including sickle cell disease, systemic lupus erythematosus, prolonged steroid used or trauma. She initially ... Read more >>

BMJ Case Rep (BMJ case reports)
[2018, 2018:]

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Paraneoplastic acral vascular syndrome.

Satish Maharaj, Simone Chang, Karan Seegobin, Carmen Isache,

Cleve Clin J Med (Cleveland Clinic journal of medicine)
[2018, 85(2):101-102]

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Mycobacteria Bovis osteomyelitis following intravesical BCG for bladder cancer.

Karan Seegobin, Satish Maharaj, Cherisse Baldeo, Carmen Isache, Bharatsinh Gharia, Lara Zuberi,

Mycobacteria Bovis osteomyelitis is a rare adverse effect after Bacillus Calmette-Guerin (BCG) intravesical therapy. A 62-year-old male presented with acute spinal cord compression three months after completing his second course of therapy for bladder cancer. The first course with intravesical BCG was complicated with an episode of hematuria. He reported ... Read more >>

IDCases (IDCases)
[2017, 10:75-78]

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Necrotizing Pseudomonas aeruginosa Community-Acquired Pneumonia: A Case Report and Review of the Literature.

Satish Maharaj, Carmen Isache, Karan Seegobin, Simone Chang, Grant Nelson,

Lung cavities are not typically associated with community-acquired pneumonia (CAP). CAP due to P. aeruginosa is rare and even less commonly causes necrotizing pneumonia. We report a case of P. aeruginosa CAP that progressed to necrotizing pneumonia and was eventually fatal. Procalcitonin (PCT) has been well investigated in guiding antibiotic ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2017, 2017:1717492]

Cited: 1 time

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Malignant syphilis: ostraceous, ulceronecrotic lesions in a patient with human immunodeficiency virus.

Girish C Mohan, Robert A Ali, Carmen L Isache, Rohit K Sharma, Charles Perniciaro,

We present a 36-year-old HIV-positive man with a sixweek history of spreading, ulcerative, and necroticcutaneous lesions. Laboratory and histopathologicexamination revealed syphilis. This case of malignantsyphilis, also known as lues maligna, is an uncommonvariant of this sexually transmitted infection. This casehighlights the importance of including malignantsyphilis in the differential diagnosis of ... Read more >>

Dermatol. Online J. (Dermatology online journal)
[2017, 23(1):]

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An unusual case of acute transverse myelitis caused by HSV-1 infection.

Danisha Figueroa, Carmen Isache, Michael Sands, Nilmarie Guzman,

Transverse myelitis is a neurological disorder of the spinal cord that can have a variety of etiologies. Herpes simplex virus (HSV) infection has been described as one of the causes, most commonly HSV type 2. We report here a case of an 18 year old male who presented with weakness that ... Read more >>

IDCases (IDCases)
[2016, 5:29-31]

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Challenges in Treating Secondary Syphilis Osteitis in an Immunocompromised Patient with a Penicillin Allergy: Case Report and Review of the Literature.

Robert Ali, Julio Perez-Downes, Firas Baidoun, Bashar Al Turk, Carmen Isache, Girish Mohan, Charles Perniciaro,

Syphilis is a sexually transmitted infection that remains fairly commonplace. The introduction of penicillin aided in curbing the incidence of disease; however, with the advent of the human immunodeficiency virus (HIV), syphilis is now on a resurgence with sometimes curious presentations. We present a case of a 36-year-old Caucasian gentleman ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2016, 2016:4983504]

Cited: 1 time

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Tuberculous Enteritis: A Rare Complication of Miliary Tuberculosis.

Danisha Figueroa, Nilmarie Guzman, Carmen Isache,

Tuberculous enteritis is a clinical rarity even in immunocompromised patients. We present a case of miliary tuberculosis with gastrointestinal involvement. A 47-year-old homosexual male from Philippines with no significant medical history presented with productive cough, night sweats, subjective fevers, shortness of breath, watery diarrhea, and 25-pound weight loss in past ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2016, 2016:6949834]

Cited: 1 time

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HTLV-1 and HIV-1 co-infection: A case report and review of the literature.

Carmen Isache, Michael Sands, Nilmarie Guzman, Danisha Figueroa,

HTLV type 1 and 2 are both involved in actively spreading epidemics, affecting over 15 million people worldwide. HTLV-1 has been described as the more clinically significant one, being associated with diseases such as adult T-cell leukemia and tropical spastic paraparesis. We report here a case of tropical spastic paraparesis ... Read more >>

IDCases (IDCases)
[2016, 4:53-55]

Cited: 1 time

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A case of disseminated intravascular coagulation secondary to Acinetobacter lwoffii and Acinetobacter baumannii bacteremia.

Candice Baldeo, Carmen Isache, Cherisse Baldeo, Abubakr Bajwa,

Bacteremia is currently one of the infections with the highest mortality in hospitals [1]. Acinetobacter lwoffii and Acinetobacter baumannii are gram-negative bacteria and both represent opportunistic pathogens. In certain cases, the management can be challenging since these organisms can be highly resistant to antimicrobial agents. Clinical illnesses associated with Acinetobacter ... Read more >>

IDCases (IDCases)
[2015, 2(3):70-71]

Cited: 1 time

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