Full Text Journal Articles by
Author Carlos Coronell


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Does oxidative stress modulate limb muscle atrophy in severe COPD patients?

Clara Fermoselle, Roberto Rabinovich, Pilar Ausín, Ester Puig-Vilanova, Carlos Coronell, Francisco Sanchez, Josep Roca, Joaquim Gea, Esther Barreiro,

Oxidative stress may differentially regulate protein loss within peripheral muscles of severe chronic obstructive pulmonary disease (COPD) patients exhibiting different body composition. Oxidation levels of proteins, myosin heavy chain (MyHC) and myonuclei, superoxide anion, antioxidants, actin, creatine kinase, carbonic anhydrase-3, ubiquitin-proteasome system, redox-signalling pathways, inflammation and muscle structure, and damage ... Read more >>

Eur Respir J (The European respiratory journal)
[2012, 40(4):851-862]

Cited: 73 times

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Injury of peripheral muscles in smokers with chronic obstructive pulmonary disease.

Mauricio Orozco-Levi, Carlos Coronell, Alba Ramírez-Sarmiento, Josep Lloreta, Juana Martínez-Llorens, Juan B Galdiz, Joaquim Gea,

Muscle injury has clinical relevance in diseased individuals because it is associated with muscle dysfunction in terms of decreased strength and/or endurance. This study was aimed at answering three questions: whether the presence of chronic obstructive pulmonary disease (COPD) is associated with peripheral muscle injury; whether muscle injury is associated ... Read more >>

Ultrastruct Pathol (Ultrastructural pathology)
[2012, 36(4):228-238]

Cited: 12 times

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Clinical correlates of apathy in patients recently diagnosed with Parkinson's disease: the ANIMO study.

Esther Cubo, Julián Benito-León, Carlos Coronell, Diana Armesto, ,

<h4>Objective</h4>Little is known about apathy in the early stages of Parkinson's disease (PD). We determined the clinical correlates of apathy in a large representative sample of patients recently diagnosed with PD (ANIMO study).<h4>Methods</h4>PD patients, diagnosed within 2 years of inclusion, were recruited in 102 outpatient clinics situated in 82 populations ... Read more >>

Neuroepidemiology (Neuroepidemiology)
[2012, 38(1):48-55]

Cited: 29 times

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Impact of apathy on health-related quality of life in recently diagnosed Parkinson's disease: the ANIMO study.

Julián Benito-León, Esther Cubo, Carlos Coronell, ,

The impact of apathy on health-related quality of life (HRQOL) in recently diagnosed Parkinson's disease (PD) has not been systematically investigated. The objective of this cross-sectional survey (ANIMO study) was to examine the contribution of apathy to HRQOL in a Spanish sample of recently diagnosed PD patients. PD patients, diagnosed ... Read more >>

Mov Disord (Movement disorders : official journal of the Movement Disorder Society)
[2012, 27(2):211-218]

Cited: 51 times

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Global muscle dysfunction as a risk factor of readmission to hospital due to COPD exacerbations.

Jordi Vilaró, Alba Ramirez-Sarmiento, Juana M A Martínez-Llorens, Teresa Mendoza, Miguel Alvarez, Natalia Sánchez-Cayado, Angeles Vega, Elena Gimeno, Carlos Coronell, Joaquim Gea, Josep Roca, Mauricio Orozco-Levi,

<h4>Unlabelled</h4>Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with several modifiable (sedentary life-style, smoking, malnutrition, hypoxemia) and non-modifiable (age, co-morbidities, severity of pulmonary function, respiratory infections) risk factors. We hypothesise that most of these risk factors may have a converging and deleterious effects on both respiratory and peripheral muscle ... Read more >>

Respir Med (Respiratory medicine)
[2010, 104(12):1896-1902]

Cited: 41 times

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Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease.

Michael T Borchers, Scott C Wesselkamper, Victor Curull, Alba Ramirez-Sarmiento, Albert Sánchez-Font, Judith Garcia-Aymerich, Carlos Coronell, Josep Lloreta, Alvar G Agusti, Joaquim Gea, John A Howington, Michael F Reed, Sandra L Starnes, Nathaniel L Harris, Mark Vitucci, Bryan L Eppert, Gregory T Motz, Kevin Fogel, Dennis W McGraw, Jay W Tichelaar, Mauricio Orozco-Levi,

Chronic obstructive pulmonary disease (COPD) is a lethal progressive lung disease culminating in permanent airway obstruction and alveolar enlargement. Previous studies suggest CTL involvement in COPD progression; however, their precise role remains unknown. Here, we investigated whether the CTL activation receptor NK cell group 2D (NKG2D) contributes to the development ... Read more >>

J Clin Invest (The Journal of clinical investigation)
[2009, 119(3):636-649]

Cited: 53 times

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[Inflammatory cytokines and repair factors in the intercostal muscles of patients with severe COPD].

Carme Casadevall, Carlos Coronell, Pilar Ausín, Juana Martínez-Llorens, Mauricio Orozco-Levi, Esther Barreiro, Joaquim Gea, ,

<h4>Objective</h4>There is disagreement regarding the local action of cytokines in the respiratory muscles of patients with chronic obstructive pulmonary disease (COPD). The objective of this study was to analyze the relationships between cytokine expression and genetic activation of the mechanisms of muscle repair.<h4>Patients and methods</h4>Twenty-five patients with severe COPD and ... Read more >>

Arch Bronconeumol (Archivos de bronconeumologia)
[2009, 45(6):279-285]

Cited: 5 times

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[Determination of maximal diaphragm strength in chronic obstructive pulmonary disease: cervical magnetic stimulation versus traditional sniff maneuver].

Juana Martínez-Llorens, Carlos Coronell, Alba Ramírez-Sarmiento, Mauricio Orozco-Levi, Josep M Espadaler, Juan Bautista Gáldiz, Joaquim Gea, ,

<h4>Objective</h4>Magnetic stimulation of the diaphragm allows its strength to be assessed. The clinical applications of this technique are becoming more widespread given that the patient's cooperation is not required. The aim of the present study was to compare this inhalation technique with traditional voluntary forced inspiration (sniff test) in a ... Read more >>

Arch Bronconeumol (Archivos de bronconeumologia)
[2006, 42(10):509-515]

Cited: 4 times

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Aging, sex differences, and oxidative stress in human respiratory and limb muscles.

Esther Barreiro, Carlos Coronell, Barbara Laviña, Alba Ramírez-Sarmiento, Mauricio Orozco-Levi, Joaquim Gea, ,

Oxidative stress is involved in the sarcopenia of aging muscles. On the grounds that ventilatory muscles are permanently active, and their activity may even increase with aging, we hypothesized that the levels of oxidative stress would probably be increased in the external intercostals of elderly healthy individuals. We conducted a ... Read more >>

Free Radic Biol Med (Free radical biology & medicine)
[2006, 41(5):797-809]

Cited: 38 times

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[Global muscle dysfunction and exacerbation of COPD: a cohort study].

Juana M Martínez-Llorens, Mauricio Orozco-Levi, María José Masdeu, Carlos Coronell, Alba Ramírez-Sarmiento, Carles Sanjuas, Joan M Broquetas, Joaquim Gea,

BACKGROUND AND OBJECTIVE:The purpose of this study was to evaluate on a prospective fashion the effects of clinical relapses of chronic obstructive pulmonary disease (COPD) on both peripheral and respiratory skeletal muscle functions. PATIENTS AND METHOD:We included 49 patients (males, 63 [11] years) who were assigned to three cohorts: a) ... Read more >>

Med Clin (Barc) (Medicina clinica)
[2004, 122(14):521-527]

Cited: 9 times

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COPD and body weight in a Mediterranean population.

Carlos Coronell, Mauricio Orozco-Levi, Joaquim Gea,

Clin Nutr (Clinical nutrition (Edinburgh, Scotland))
[2002, 21(5):437; author reply 437-8]

Cited: 9 times

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