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The α-arrestin ARRDC3 is an Emerging Multifunctional Adaptor Protein in Cancer.

Helen Wedegaertner, Wen-An Pan, Carlos C Gonzalez, David J Gonzalez, Joann Trejo,

<h4>Significance</h4>Adaptor proteins control the spatial and temporal dynamics of cellular signaling. Dysregulation of adaptor protein function can cause aberrant cell signaling and promote cancer. The arrestin adaptor proteins are known to regulate signaling by the superfamily of G protein-coupled receptors (GPCRs). GPCRs are highly druggable and implicated in cancer progression. ... Read more >>

Antioxid Redox Signal (Antioxidants & redox signaling)
[2021, :]

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