Full Text Journal Articles by
Author Carlos Brotons

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Educational Impact on Apixaban Adherence in Atrial Fibrillation (the AEGEAN STUDY): A Randomized Clinical Trial.

Gilles Montalescot, Carlos Brotons, Bernard Cosyns, Harry J Crijns, Armando D'Angelo, Ludovic Drouet, Franz Eberli, Deirdre A Lane, Bruno Besse, Anthony Chan, Eric Vicaut, Harald Darius, ,

INTRODUCTION:Adherence to non-vitamin-K oral anticoagulants (NOACs) may be lower than to vitamin K antagonists because NOACs do not require routine monitoring. OBJECTIVE:We assessed the impact of an educational program on adherence and persistence with apixaban in patients with non-valvular atrial fibrillation (NVAF). METHODS:Patients with NVAF eligible for NOACs with one ... Read more >>

Am J Cardiovasc Drugs (American journal of cardiovascular drugs : drugs, devices, and other interventions)
[2020, 20(1):61-71]

Cited: 0 times

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Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology.

Massimo F Piepoli, Ana Abreu, Christian Albus, Marco Ambrosetti, Carlos Brotons, Alberico L Catapano, Ugo Corra, Bernard Cosyns, Christi Deaton, Ian Graham, Arno Hoes, Maja-Lisa Lochen, Benedetta Matrone, Josep Redon, Naveed Sattar, Yvo Smulders, Monica Tiberi,

European guidelines on cardiovascular prevention in clinical practice were first published in 1994 and have been regularly updated, most recently in 2016, by the Sixth European Joint Task Force. Given the amount of new information that has become available since then, components from the task force and experts from the ... Read more >>

Eur J Prev Cardiol (European journal of preventive cardiology)
[2020, 27(2):181-205]

Cited: 0 times

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Lifestyle behaviours in patients with established cardiovascular diseases: a European observational study.

Diana Fernández, Carlos Brotons, Irene Moral, Mateja Bulc, Mélanie Afonso, Hülya Akan, Susana Pinto, Jasna Vucak, Carlos Manuel da Silva Martins,

BACKGROUND:Patients who have experienced a cardiovascular clinical event such as a myocardial infarction or stroke qualify for intensive risk factor evaluation and management. The aim of this study is to explore lifestyle changes as well as the achievement of targets for risk factors in patients with established cardiovascular disease. METHODS:Cross-sectional ... Read more >>

BMC Fam Pract (BMC family practice)
[2019, 20(1):162]

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Predictive validity of the risk SCORE model in a Mediterranean population with dyslipidemia.

Vicente Bertomeu-González, Cristina Soriano Maldonado, Jesús Bleda-Cano, Sara Carrascosa-Gonzalvo, Jorge Navarro-Perez, Adriana López-Pineda, Concepción Carratalá-Munuera, Vicente F Gil Guillén, Jose A Quesada, Carlos Brotons, Domingo Orozco-Beltrán,

BACKGROUND AND AIMS:Cholesterol treatment for the primary prevention of cardiovascular disease is based on cardiovascular risk, as assessed by the SCORE (Systematic COronary Risk Evaluation) scale. This study aimed to assess the predictive value and clinical utility of the SCORE scale for preventing cardiovascular events and all-cause mortality in people ... Read more >>

Atherosclerosis (Atherosclerosis)
[2019, 290:80-86]

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Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium.

Bradley C Johnston, Dena Zeraatkar, Mi Ah Han, Robin W M Vernooij, Claudia Valli, Regina El Dib, Catherine Marshall, Patrick J Stover, Susan Fairweather-Taitt, Grzegorz Wójcik, Faiz Bhatia, Russell de Souza, Carlos Brotons, Joerg J Meerpohl, Chirag J Patel, Benjamin Djulbegovic, Pablo Alonso-Coello, Malgorzata M Bala, Gordon H Guyatt,

This article has been corrected. The original version (PDF) is appended to this article as a Supplement. Description:Dietary guideline recommendations require consideration of the certainty in the evidence, the magnitude of potential benefits and harms, and explicit consideration of people's values and preferences. A set of recommendations on red meat ... Read more >>

Ann. Intern. Med. (Annals of internal medicine)
[2019, 171(10):756-764]

Cited: 2 times

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Epidemiology, risk factors, and opportunities for prevention of cardiovascular disease in individuals of South Asian ethnicity living in Europe.

Miguel Cainzos-Achirica, Ugo Fedeli, Naveed Sattar, Charles Agyemang, Anne K Jenum, John W McEvoy, Jack D Murphy, Carlos Brotons, Roberto Elosua, Usama Bilal, Alka M Kanaya, Namratha R Kandula, Pablo Martinez-Amezcua, Josep Comin-Colet, Xavier Pinto,

South Asian (SA) individuals represent a large, growing population in a number of European countries. These individuals, particularly first-generation SA immigrants, are at higher risk of developing type 2 diabetes, atherogenic dyslipidaemia, and coronary heart disease than most other racial/ethnic groups living in Europe. SAs also have an increased risk ... Read more >>

Atherosclerosis (Atherosclerosis)
[2019, 286:105-113]

Cited: 1 time

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Circulating non-coding RNAs in biomarker-guided cardiovascular therapy: a novel tool for personalized medicine?

David de Gonzalo-Calvo, Angela Vea, Christian Bär, Jan Fiedler, Liam S Couch, Carlos Brotons, Vicenta Llorente-Cortes, Thomas Thum,

Current clinical guidelines emphasize the unmet need for technological innovations to guide physician decision-making and to transit from conventional care to personalized cardiovascular medicine. Biomarker-guided cardiovascular therapy represents an interesting approach to inform tailored treatment selection and monitor ongoing efficacy. However, results from previous publications cast some doubts about the ... Read more >>

Eur. Heart J. (European heart journal)
[2019, 40(20):1643-1650]

Cited: 9 times

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Nalmefene, Given as Needed, in the Routine Treatment of Patients with Alcohol Dependence: An Interventional, Open-Label Study in Primary Care.

Philippe Castera, Edmund Stewart, Josef Großkopf, Carlos Brotons, Maiken Brix Schou, Doris Zhang, Björn Steiniger Brach, Didier Meulien, ,

AIMS:This 12-week, open-label, primary care study (NCT02195817) evaluated the efficacy and safety of nalmefene, taken as needed, to reduce alcohol consumption in adults with a diagnosis of alcohol dependence and drinking at least at high drinking risk levels (DRL, > 60 g/day for men, > 40 g/day for women). METHODS:Following ... Read more >>

Eur Addict Res (European addiction research)
[2018, 24(6):293-303]

Cited: 1 time

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Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.

J Michael Gaziano, Carlos Brotons, Rosa Coppolecchia, Claudio Cricelli, Harald Darius, Philip B Gorelick, George Howard, Thomas A Pearson, Peter M Rothwell, Luis Miguel Ruilope, Michal Tendera, Gianni Tognoni, ,

BACKGROUND:The use of aspirin in the primary prevention of cardiovascular events remains controversial. We aimed to assess the efficacy and safety of aspirin versus placebo in patients with a moderate estimated risk of a first cardiovascular event. METHODS:ARRIVE is a randomised, double-blind, placebo-controlled, multicentre study done in seven countries. Eligible ... Read more >>

Lancet (Lancet (London, England))
[2018, 392(10152):1036-1046]

Cited: 44 times

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Estimation of Lifetime Risk of Cardiovascular Disease (IBERLIFERISK): A New Tool for Cardiovascular Disease Prevention in Primary Care.

Carlos Brotons, Irene Moral, Diana Fernández, Mireia Puig, Eva Calvo Bonacho, Paloma Martínez Muñoz, Carlos Catalina Romero, Luis Javier Quevedo Aguado,

INTRODUCTION AND OBJECTIVES:To develop a predictive function of lifetime cardiovascular risk, including morbidity and mortality, in a healthy working population in Spain. METHODS:Retrospective cohort study. We selected healthy workers, aged 18 to 65 years, with no history of cardiovascular disease, who underwent a health assessment between 2004 and 2007. We ... Read more >>

Rev Esp Cardiol (Engl Ed) (Revista Espanola De Cardiologia (English Ed.))
[2019, 72(7):562-568]

Cited: 1 time

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EUROPREV (European Network for Prevention and Health Promotion).

Carlos Brotons,

Aten Primaria (Atencion primaria)
[2018, 50 Suppl 1:3]

Cited: 0 times

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The Ideal Lipid Report: A Need for Consensus.

Juan Pedro-Botet, Luis Rodríguez-Padial, Carlos Brotons, Margarita Esteban-Salán, Aurora García-Lerín, Xavier Pintó, Iñaki Lekuona, Jordi Ordóñez-Llanos,

Rev Esp Cardiol (Engl Ed) (Revista Espanola De Cardiologia (English Ed.))
[2018, 71(7):512-514]

Cited: 0 times

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Urinary Proteome Analysis Identified Neprilysin and VCAM as Proteins Involved in Diabetic Nephropathy.

Elena Guillén-Gómez, Beatriz Bardají-de-Quixano, Sílvia Ferrer, Carlos Brotons, Mark A Knepper, Montserrat Carrascal, Joaquin Abian, José M Mas, Francesca Calero, José A Ballarín, Patricia Fernández-Llama,

Urinary proteome was analyzed and quantified by tandem mass tag (TMT) labeling followed by bioinformatics analysis to study diabetic nephropathy (DN) pathophysiology and to identify biomarkers of a clinical outcome. We included type 2 diabetic normotensive non-obese males with (n = 9) and without (n = 11) incipient DN (microalbuminuria). ... Read more >>

J Diabetes Res (Journal of diabetes research)
[2018, 2018:6165303]

Cited: 1 time

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Homogenization of the lipid profile values.

Juan Pedro-Botet, Luis Rodríguez-Padial, Carlos Brotons, Margarita Esteban-Salán, Aurora García-Lerín, Xavier Pintó, Iñaki Lekuona, Jordi Ordóñez-Llanos,

Analytical reports from the clinical laboratory are essential to guide clinicians about what lipid profile values should be considered altered and, therefore, require intervention. Unfortunately, there is a great heterogeneity in the lipid values reported as "normal, desirable, recommended or referenced" by clinical laboratories. This can difficult clinical decisions and ... Read more >>

Clin Investig Arterioscler (Clinica E Investigacion En Arteriosclerosis)
[2018, 30(1):36-48]

Cited: 0 times

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Perception of preventive care and readiness for lifestyle change in rural and urban patients in Poland: a questionnaire study.

Maciek Godycki-Cwirko, Lech Panasiuk, Carlos Brotons, Mateja Bulc, Izabela Zakowska,

The idiosyncrasies of rural health demand further research to instigate rural health initiatives and to monitor progress in rural health care. In 2008, a study examined health-related behaviour, perception of importance of preventive interventions, readiness to change lifestyle and willingness to receive support from GPs, according to gender and place ... Read more >>

Ann Agric Environ Med (Annals of agricultural and environmental medicine : AAEM)
[2017, 24(4):732-738]

Cited: 0 times

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Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European Union.

Jürgen Rehm, Peter Anderson, Jose Angel Arbesu Prieto, Iain Armstrong, Henri-Jean Aubin, Michael Bachmann, Nuria Bastida Bastus, Carlos Brotons, Robyn Burton, Manuel Cardoso, Joan Colom, Daniel Duprez, Gerrit Gmel, Antoni Gual, Ludwig Kraus, Reinhold Kreutz, Helena Liira, Jakob Manthey, Lars Møller, Ľubomír Okruhlica, Michael Roerecke, Emanuele Scafato, Bernd Schulte, Lidia Segura-Garcia, Kevin David Shield, Cristina Sierra, Konstantin Vyshinskiy, Marcin Wojnar, José Zarco,

BACKGROUND:Hazardous and harmful alcohol use and high blood pressure are central risk factors related to premature non-communicable disease (NCD) mortality worldwide. A reduction in the prevalence of both risk factors has been suggested as a route to reach the global NCD targets. This study aims to highlight that screening and ... Read more >>

BMC Med (BMC Medicine)
[2017, 15(1):173]

Cited: 6 times

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Main messages for primary care from the 2016 European Guidelines on cardiovascular disease prevention in clinical practice.

Massimo F Piepoli, Arno W Hoes, Carlos Brotons, Richard F D Hobbs, Ugo Corra, ,

In 2016, a new version of the European Guidelines on Cardiovascular Prevention was released, representing a partnership between the European Association for Cardiovascular Prevention and Rehabilitation of the European Society of Cardiology (ESC) and nine European societies, including Wonca-Europe. The ESC guidelines underscore the importance of a lifetime approach to ... Read more >>

Eur J Gen Pract (The European journal of general practice)
[2018, 24(1):51-56]

Cited: 7 times

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[2016 European guidelines on cardiovascular disease prevention in clinical practice. The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts. Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation].

Massimo F Piepoli, Arno W Hoes, Stefan Agewall, Christian Albus, Carlos Brotons, Alberico L Catapano, Marie-Therese Cooney, Ugo Corrà, Bernard Cosyns, Christi Deaton, Ian Graham, Michael Stephen Hall, F D Richard Hobbs, Maja-Lisa Løchen, Herbert Löllgen, Pedro Marques-Vidal, Joep Perk, Eva Prescott, Josep Redon, Dimitrios J Richter, Naveed Sattar, Yvo Smulders, Monica Tiberi, H Bart van der Worp, Ineke van Dis, W M Monique Verschuren,

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2017, 18(7):547-612]

Cited: 12 times

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Association Between Improvement in Cardiovascular Risk Profile and Changes in Sickness Absence: Results of the ICARIA Study.

Eva Calvo-Bonacho, Carlos Catalina-Romero, Martha Cabrera, Carlos Fernández-Labandera, Miguel Ángel Sánchez Chaparro, Carlos Brotons, Luis Miguel Ruilope,

The purpose of this study was to investigate whether changes in cardiovascular risk (CVR) are associated with the length and cost of sickness absence.A prospective cohort of 179 186 participants was evaluated. Each participant's CVR (SCORE) was assessed on 2 consecutive medical examinations, approximately 1 year apart (365 ± 90 days). ... Read more >>

Rev Esp Cardiol (Engl Ed) (Revista Espanola De Cardiologia (English Ed.))
[2017, 70(11):941-951]

Cited: 0 times

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Erratum to "Clinical consequences of using the new cardiovascular risk tables SCORE OP in patients aged over 65 years".

Carlos Brotons, Irene Moral, Diana Fernández, Lluis Cuixart, Alex Muñoz, Anna Soteras, Mireia Puig, Xavier Joaniquet, Albert Casasa,

Med Clin (Barc) (Medicina clinica)
[2017, 148(5):241]

Cited: 0 times

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[2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)].

Marco Roffi, Carlo Patrono, Jean-Philippe Collet, Christian Mueller, Marco Valgimigli, Felicita Andreotti, Jeroen J Bax, Michael A Borger, Carlos Brotons, Derek P Chew, Baris Gencer, Gerd Hasenfuss, Keld Kjeldsen, Patrizio Lancellotti, Ulf Landmesser, Julinda Mehilli, Debabrata Mukherjee, Robert F Storey, Stephan Windecker,

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2016, 17(10):831-872]

Cited: 15 times

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2016 European Guidelines on cardiovascular disease prevention in clinical practice.

Massimo F Piepoli, Arno W Hoes, Stefan Agewall, Christian Albus, Carlos Brotons, Alberico L Catapano, Marie-Therese Cooney, Ugo Corrà, Bernard Cosyns, Christi Deaton, Ian Graham, Michael Stephen Hall, F D Richard Hobbs, Maja-Lisa Løchen, Herbert Löllgen, Pedro Marques-Vidal, Joep Perk, Eva Prescott, Josep Redon, Dimitrios J Richter, Naveed Sattar, Yvo Smulders, Monica Tiberi, H Bart van der Worp, Ineke van Dis, W M Monique Verschuren,

Rev Esp Cardiol (Engl Ed) (Revista Espanola De Cardiologia (English Ed.))
[2016, 69(10):939]

Cited: 18 times

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Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older.

Anthony L Cunningham, Himal Lal, Martina Kovac, Roman Chlibek, Shinn-Jang Hwang, Javier Díez-Domingo, Olivier Godeaux, Myron J Levin, Janet E McElhaney, Joan Puig-Barberà, Carline Vanden Abeele, Timo Vesikari, Daisuke Watanabe, Toufik Zahaf, Anitta Ahonen, Eugene Athan, Jose F Barba-Gomez, Laura Campora, Ferdinandus de Looze, H Jackson Downey, Wayne Ghesquiere, Iris Gorfinkel, Tiina Korhonen, Edward Leung, Shelly A McNeil, Lidia Oostvogels, Lars Rombo, Jan Smetana, Lily Weckx, Wilfred Yeo, Thomas C Heineman, ,

A trial involving adults 50 years of age or older (ZOE-50) showed that the herpes zoster subunit vaccine (HZ/su) containing recombinant varicella-zoster virus glycoprotein E and the AS01B adjuvant system was associated with a risk of herpes zoster that was 97.2% lower than that associated with placebo. A second trial ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2016, 375(11):1019-1032]

Cited: 172 times

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2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR).

, Massimo F Piepoli, Arno W Hoes, Stefan Agewall, Christian Albus, Carlos Brotons, Alberico L Catapano, Marie-Therese Cooney, Ugo Corrà, Bernard Cosyns, Christi Deaton, Ian Graham, Michael Stephen Hall, F D Richard Hobbs, Maja-Lisa Løchen, Herbert Löllgen, Pedro Marques-Vidal, Joep Perk, Eva Prescott, Josep Redon, Dimitrios J Richter, Naveed Sattar, Yvo Smulders, Monica Tiberi, H Bart van der Worp, Ineke van Dis, W M Monique Verschuren,

Atherosclerosis (Atherosclerosis)
[2016, 252:207-274]

Cited: 96 times

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[Clinical consequences of using the new cardiovascular risk tables SCORE OP in patients aged over 65 years].

Carlos Brotons, Irene Moral, Diana Fernández, Lluis Cuixart, Alex Muñoz, Anna Soteras, Mireia Puig, Xavier Joaniquet, Albert Casasa,

Estimating cardiovascular risk with SCORE is not recommended in persons over 65 years. SCORE investigators have recently published specific tables for older people (SCORE Older Persons [SCORE OP]). The aim of this study is to assess the impact of using SCORE OP tables on a Spanish population aged over 64 ... Read more >>

Med Clin (Barc) (Medicina clinica)
[2016, 147(9):381-386]

Cited: 4 times

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