Full Text Journal Articles by
Author Camilla Muccini

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Brief Report: Syphilis Incidence and Effect on Viral Load, CD4, and CD4/CD8 Ratio in a Thai Cohort of Predominantly Men Who Have Sex With Men Living With HIV.

Camilla Muccini, Trevor A Crowell, Suteeraporn Pinyakorn, Eugène Kroon, Carlo Sacdalan, Jintanat Ananworanich, Sandhya Vasan, Nittaya Phanuphak, Donn J Colby, ,

<h4>Background</h4>Syphilis has been increasing in the past years, especially among men who have sex with men (MSM). The aim of the study was to assess syphilis prevalence and incidence and changes in CD4 count and viremia in the RV254 cohort of persons living with HIV who initiated antiretroviral therapy during ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):219-223]

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Cerebrospinal fluid viral replication and burden of resistance in three HIV-1-infected people taking Ibalizumab with multiple drug class-wide resistance.

Camilla Muccini, Vincenzo Spagnuolo, Diana Canetti, Alba Bigoloni, Massimo Cernuschi, Michela Franzin, Michela Sampaolo, Antonella Castagna,

AIDS (AIDS (London, England))
[2020, 34(14):2152-2155]

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Changes in homeostatic model assessment for insulin resistance (HOMA-IR) index in treated HIV-1 infected people on virological suppression who switched to a different antiretroviral regimen.

Camilla Muccini, Laura Galli, Andrea Poli, Matteo Chiurlo, Martina Ranzenigo, Hamid Hasson, Antonella Castagna,

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, :]

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SARS-CoV-2 IgG/IgM Rapid Test as a Diagnostic Tool in Hospitalized Patients and Healthcare Workers, at a large Teaching Hospital in northern Italy, during the 2020 COVID-19 Pandemic.

Diana Canetti, Raffaele Dell'Acqua, Niccolò Riccardi, Liviana Della Torre, Alba Bigoloni, Camilla Muccini, Elena Bruzzesi, Martina Ranzenigo, Matteo Chiurlo, Sara Racca, Cristina Galli, Antonella Castagna, Giuseppe Tambussi, Adriano Lazzarin,

We describe the outcome of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) IgG/IgM rapid test, and discuss the potential suitability of antibody testing. Retrospective single cohort study on patients with suspected Coronavirus Disease 2019 (COVID-19) and asymptomatic Healthcare Workers, enrolled from March to April 2020. Subjects had quantitative PCR ... Read more >>

New Microbiol (The new microbiologica)
[2020, 43(4):161-165]

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Candidemia in COVID-19 patients: incidence and characteristics in a prospective cohort compared to historical non-COVID-19 controls.

Andrea Mastrangelo, Bruno Nicolò Germinario, Marica Ferrante, Claudia Frangi, Raffaele Li Voti, Camilla Muccini, Marco Ripa, ,

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Secondary infections in patients hospitalized with COVID-19: incidence and predictive factors.

Marco Ripa, Laura Galli, Andrea Poli, Chiara Oltolini, Vincenzo Spagnuolo, Andrea Mastrangelo, Camilla Muccini, Giacomo Monti, Giacomo De Luca, Giovanni Landoni, Lorenzo Dagna, Massimo Clementi, Patrizia Rovere Querini, Fabio Ciceri, Moreno Tresoldi, Adriano Lazzarin, Alberto Zangrillo, Paolo Scarpellini, Antonella Castagna, ,

<h4>Objectives</h4>The aim of our study was to describe the incidence and predictive factors of secondary infections in patients with coronavirus disease 2019 (COVID-19).<h4>Methods</h4>This was a cohort study of patients hospitalized with COVID-19 at IRCCS San Raffaele Hospital between 25th February and 6th April 2020 (NCT04318366). We considered secondary bloodstream infections ... Read more >>

Clin Microbiol Infect (Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases)
[2020, :]

Cited: 1 time

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CSF viral replication and burden of resistance in three HIV-1-infected people taking Ibalizumab with multiple drug class-wide resistance.

Camilla Muccini, Vincenzo Spagnuolo, Diana Canetti, Alba Bigoloni, Massimo Cernuschi, Michela Franzin, Michela Sampaolo, Antonella Castagna,

AIDS (AIDS (London, England))
[2020, :]

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Central nervous system safety during brief analytic treatment interruption of antiretroviral therapy within four HIV remission trials: an observational study in acutely treated people living with HIV.

Joanna Hellmuth, Camilla Muccini, Donn J Colby, Eugène Kroon, Mark de Souza, Trevor A Crowell, Phillip Chan, Carlo Sacdalan, Jintana Intasan, Khunthalee Benjapornpong, Somporn Tipsuk, Suwanna Puttamaswin, Nitiya Chomchey, Victor Valcour, Michal Sarnecki, Frank Tomaka, Shelly J Krebs, Bonnie M Slike, Linda L Jagodzinski, Netsiri Dumrongpisutikul, Napapon Sailasuta, Vishal Samboju, Nelson L Michael, Merlin L Robb, Sandhya Vasan, Jintanat Ananworanich, Praphan Phanuphak, Nittaya Phanuphak, Robert Paul, Serena Spudich,

<h4>Background</h4>The central nervous system (CNS) is a likely reservoir of HIV, vulnerable to viral rebound, inflammation, and clinical changes upon stopping antiretroviral therapy (ART). It is critical to evaluate the CNS safety of studies using analytic treatment interruption (ATI) to assess HIV remission.<h4>Methods</h4>Thirty participants who started ART during acute HIV ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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How to RESPOND to Modern Challenges for People Living with HIV: A Profile for a New Cohort Consortium.

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<h4>Background</h4>the International Cohort Consortium of Infectious Disease (RESPOND) is a collaboration dedicated to research on HIV and other infectious diseases.<h4>Methods</h4>RESPOND is a flexible organization, with several independent substudies operating under one shared governance. HIV-related variables, including full antiretroviral therapy (ART) history, are collected annually for all participants and merged with ... Read more >>

Microorganisms (Microorganisms)
[2020, 8(8):]

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Dynamics of HIV-1 POL antibodies after ART in chronic HIV-1 infection.

Francesca Rinaldi, Serena Rolla, Laura Galli, Andrea Poli, Camilla Muccini, Andrea Mastrangelo, Cinzia Tavano, Adriano Lazzarin, Alessandro Bartoloni, Antonella Castagna,

The aim of this retrospective study was to evaluate Western Blot (WB) antibody response against HIV-1 Pol proteins in people on ≥12 months of Antiretroviral Therapy (ART) and factors associated with a negative HIV-1 Pol response or with its seroreversion from positive to negative. Multivariate logistic regression models were performed ... Read more >>

New Microbiol (The new microbiologica)
[2020, 43(2):55-57]

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Brief Report: Association Between Low HIV-1 DNA and Western Blot Reactivity to HIV-1 Pol in Chronically Infected Individuals.

Camilla Muccini, Laura Galli, Vincenzo Spagnuolo, Andrea Poli, Serena Rolla, Andrea Mastrangelo, Francesca Rinaldi, Antonella Castagna,

BACKGROUND:The aim of the study was to evaluate whether negative HIV-1 pol on Western blot (WB) was associated with low HIV-DNA in adults with chronic HIV-1 infection and suppressive antiretroviral therapy. METHODS:Cross-sectional parent study of the APACHE trial, conducted in subjects with chronic infection, HIV-1 RNA <50 copies/mL for ≥10 ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 82(4):373-376]

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Retrospective study on the outcome of two-drug regimens based on dolutegravir plus one reverse transcriptase inhibitor in virologically-suppressed HIV-infected patients.

Nadia Galizzi, Andrea Poli, Laura Galli, Camilla Muccini, Andrea Mastrangelo, Raffaele Dell'Acqua, Myriam Maillard, Simona Bossolasco, Paola Cinque, Adriano Lazzarin, Antonella Castagna, Nicola Gianotti,

This was a retrospective study on the efficacy and drug resistance mutations selected at virological failure (VF) in prospectively-followed HIV-infected patients switched to dolutegravir plus rilpivirine (DTG+RPV) or lamivudine (DTG+3TC) while virologically suppressed (HIV-RNA <50 copies/mL). VF was defined as HIV-RNA >50 copies/mL in two consecutive determinations or in a ... Read more >>

Int J Antimicrob Agents (International journal of antimicrobial agents)
[2020, 55(3):105893]

Cited: 1 time

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Homeostatic model assessment for insulin resistance index trajectories in HIV-infected patients treated with different first-line antiretroviral regimens.

Nicola Gianotti, Camilla Muccini, Laura Galli, Andrea Poli, Vincenzo Spagnuolo, Andrea Andolina, Nadia Galizzi, Marco Ripa, Emanuela Messina, Pier Marco Piatti, Adriano Lazzarin, Antonella Castagna,

<h4>Objective</h4>To describe the trajectories of the homeostatic model assessment for insulin resistance (HOMA-IR) index in a cohort of HIV-1 infected patients during their first-line antiretroviral (ART) regimen.<h4>Methods</h4>Retrospective analysis of naïve patients who started ART from 2007 at the Infectious Diseases Unit of the San Raffaele Hospital, Milan. We included patients ... Read more >>

J Med Virol (Journal of medical virology)
[2019, 91(11):1937-1943]

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Analytical treatment interruption in chronic HIV-1 infection: time and magnitude of viral rebound in adults with 10 years of undetectable viral load and low HIV-DNA (APACHE study).

Antonella Castagna, Camilla Muccini, Laura Galli, Alba Bigoloni, Andrea Poli, Vincenzo Spagnuolo, Silvia Nozza, Sara Racca, Andrea Galli, Paola Cinque, Elisabetta Carini, Adriano Lazzarin,

<h4>Objectives</h4>Despite the fact that there are individuals who have chronic HIV infection, few studies have investigated ART interruption in this setting. The aim of this study was to evaluate the ability to spontaneously control viral replication during analytical treatment interruption (ATI) in adults with chronic HIV-1 infection, on ART, with ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2019, 74(7):2039-2046]

Cited: 3 times

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Increased dose of dolutegravir as a potential rescue therapy in multi-experienced patients.

Davide Ferrari, Vincenzo Spagnuolo, Monica Manca, Alba Bigoloni, Camilla Muccini, Giuseppe Banfi, Massimo Locatelli, Antonella Castagna,

<h4>Background</h4>The pilot Phase IIb VIKING study suggested that dolutegravir (DTG), an HIV integrase inhibitor (INI), is efficacious in INI-resistant patients at the 50 mg twice-daily dose. However, DTG response was most reduced in subjects carrying resistance-associated mutations at position G140 and Q148. These mutations can cause a 10-20-fold reduced susceptibility ... Read more >>

Antivir Ther (Antiviral therapy)
[2019, 24(1):69-72]

Cited: 1 time

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Brief Report: Hyperbilirubinemia Is Associated With a Decreased Risk of Carotid Atherosclerosis in HIV-Infected Patients on Virological Suppression.

Camilla Muccini, Laura Galli, Andrea Poli, Alessia Carbone, Myriam Maillard, Maria Cristina Giusti, Vincenzo Spagnuolo, Alba Bigoloni, Monica Guffanti, Nicola Gianotti, Adriano Lazzarin, Antonella Castagna,

<h4>Objective</h4>To investigate the association between total, direct, and indirect bilirubin and the presence of carotid lesions in a large sample of HIV-1-infected patients on virological suppression.<h4>Design</h4>Retrospective study on adult HIV-1-infected patients, with a carotid ultrasound (CUS) examination performed between January 2008 and August 2016, with HIV-RNA <50 copies per milliliter ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2018, 79(5):617-623]

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Immune activation, inflammation and HIV DNA after 96 weeks of ATV/r monotherapy: a MODAt substudy.

Esther Merlini, Laura Galli, Camilla Tincati, Elvira S Cannizzo, Andrea Galli, Nicola Gianotti, Giuseppe Ancona, Camilla Muccini, Antonella d'Arminio Monforte, Giulia Marchetti, Antonella Castagna, ,

Antivir Ther (Antiviral therapy)
[2018, 23(7):633-637]

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Efficacy and safety of switching from branded to generic antiretrovirals in virologically suppressed HIV-infected patients.

Nicola Gianotti, Andrea Poli, Laura Galli, Michela Franzin, Patrizia Tadini, Nadia Galizzi, Alessia Carbone, Marco Merli, Camilla Muccini, Chiara Oltolini, Andrea Andolina, Vincenzo Spagnuolo, Adriano Lazzarin, Antonella Castagna,

<h4>Background</h4>Aim of this study was to evaluate the efficacy and the safety of switching from branded to generic antiretrovirals in patients with HIV-RNA <50 copies/mL.<h4>Methods</h4>Matched-cohort study of patients followed at a single clinical center. Since September 2014, all patients with HIV-RNA <50 copies/mL who were receiving branded lamivudine or zidovudine/lamivudine ... Read more >>

PLoS One (PloS one)
[2017, 12(8):e0182007]

Cited: 3 times

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An observational, retrospective analysis evaluating switching to raltegravir plus abacavir/lamivudine in HIV-1-infected patients: the ORASWIRAL study.

Laura Galli, Andrea Poli, Camilla Muccini, Nadia Galizzi, Anna Danise, Vincenzo Spagnuolo, Nicola Gianotti, Elisabetta Carini, Adriano Lazzarin, Antonella Castagna,

Infect Dis (Lond) (Infectious diseases (London, England))
[2018, 50(3):220-222]

Cited: 0 times

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