Full Text Journal Articles by
Author Cameron O Scarlett


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A randomized, double-blind, dose-ranging, pilot trial of piperine with resveratrol on the effects on serum levels of resveratrol.

Howard H Bailey, Jeremy J Johnson, Taja Lozar, Cameron O Scarlett, Barbara W Wollmer, KyungMann Kim, Thomas Havinghurst, Nihal Ahmad,

Resveratrol (3,4,5-trihydroxystilbene) is a naturally occurring phytoalexin with purported health-promoting effects, but with limited oral bioavailability. Our prior murine modeling research observed enhanced resveratrol bioavailability with piperine co-administration. In this study, single-dose pharmacokinetics of resveratrol with or without piperine and the associated toxicities were studied on a cohort of healthy ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, 30(3):285-290]

Cited: 0 times

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Trehalose Synthesis Contributes to Osmotic Stress Tolerance and Virulence of the Bacterial Wilt Pathogen Ralstonia solanacearum.

April M MacIntyre, John X Barth, Molly C Pellitteri Hahn, Cameron O Scarlett, Stéphane Genin, Caitilyn Allen,

The xylem-dwelling plant pathogen <i>Ralstonia solanacearum</i> changes the chemical composition of host xylem sap during bacterial wilt disease. The disaccharide trehalose, implicated in stress tolerance across all kingdoms of life, is enriched in sap from <i>R. solanacearum</i>-infected tomato plants. Trehalose in xylem sap could be synthesized by the bacterium, the ... Read more >>

Mol Plant Microbe Interact (Molecular plant-microbe interactions : MPMI)
[2020, 33(3):462-473]

Cited: 3 times

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Low-fat yogurt consumption reduces biomarkers of chronic inflammation and inhibits markers of endotoxin exposure in healthy premenopausal women: a randomised controlled trial.

Ruisong Pei, Diana M DiMarco, Kelley K Putt, Derek A Martin, Qinlei Gu, Chureeporn Chitchumroonchokchai, Heather M White, Cameron O Scarlett, Richard S Bruno, Bradley W Bolling,

The anti-inflammatory mechanisms of low-fat dairy product consumption are largely unknown. The objective of this study was to determine whether low-fat yogurt reduces biomarkers of chronic inflammation and endotoxin exposure in women. Premenopausal women (BMI 18·5-27 and 30-40 kg/m2) were randomised to consume 339 g of low-fat yogurt (yogurt non-obese ... Read more >>

Br J Nutr (The British journal of nutrition)
[2017, 118(12):1043-1051]

Cited: 17 times

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Enhancing the bioavailability of resveratrol by combining it with piperine.

Jeremy J Johnson, Minakshi Nihal, Imtiaz A Siddiqui, Cameron O Scarlett, Howard H Bailey, Hasan Mukhtar, Nihal Ahmad,

<h4>Scope</h4>Resveratrol (3,5,4'-trihydroxystilbene) is a phytoalexin shown to possess a multitude of health-promoting properties in pre-clinical studies. However, the poor in vivo bioavailability of resveratrol due to its rapid metabolism is being considered as a major obstacle in translating its effects in humans. In this study, we examined the hypothesis that ... Read more >>

Mol Nutr Food Res (Molecular nutrition & food research)
[2011, 55(8):1169-1176]

Cited: 111 times

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Data Self-Recalibration and Mixture Mass Fingerprint Searching (DASER-MMF) to enhance protein identification within complex mixtures.

Ryan M Danell, Severine A Ouvry-Patat, Cameron O Scarlett, J Paul Speir, Christoph H Borchers,

A novel algorithm based on Data Self-Recalibration and a subsequent Mixture Mass Fingerprint search (DASER-MMF) has been developed to improve the performance of protein identification from online 1D and 2D-LC-MS/MS experiments conducted on high-resolution mass spectrometers. Recalibration of 40% to 75% of the MS spectra in a human serum dataset ... Read more >>

J Am Soc Mass Spectrom (Journal of the American Society for Mass Spectrometry)
[2008, 19(12):1914-1925]

Cited: 2 times

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Ubiquitylation of proliferating cell nuclear antigen and recruitment of human DNA polymerase eta.

Nana Nikolaishvili-Feinberg, G Scott Jenkins, Kathleen R Nevis, Dean P Staus, Cameron O Scarlett, Keziban Unsal-Kaçmaz, William K Kaufmann, Marila Cordeiro-Stone,

This study investigated the requirement for ubiquitylation of PCNA at lysine 164 during polymerase eta-dependent translesion synthesis (TLS) of site-specific cis-syn cyclobutane thymine dimers (T (wedge)T). The in vitro assay recapitulated origin-dependent initiation, fork assembly, and semiconservative, bidirectional replication of double-stranded circular DNA substrates. A phosphocellulose column was used to ... Read more >>

Biochemistry (Biochemistry)
[2008, 47(13):4141-4150]

Cited: 14 times

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Three male germline-specific aldolase A isozymes are generated by alternative splicing and retrotransposition.

Soumya A Vemuganti, Timothy A Bell, Cameron O Scarlett, Carol E Parker, Fernando Pardo-Manuel de Villena, Deborah A O'Brien,

Enzymes in the glycolytic pathway of mammalian sperm are modified extensively and are localized in the flagellum, where several are tightly bound to the fibrous sheath. This study provides the first evidence for three novel aldolase isozymes in mouse sperm, two encoded by Aldoart1 and Aldoart2 retrogenes on different chromosomes ... Read more >>

Dev Biol (Developmental biology)
[2007, 309(1):18-31]

Cited: 29 times

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Identification of components of protein complexes.

Carol E Parker, Maria R Warren, David R Loiselle, Nedyalka N Dicheva, Cameron O Scarlett, Christoph H Borchers,

Protocols are given for a variety of techniques used in protein identification of complexes, including identification of in-gel separated proteins and LC-MS/MS. Gels, staining procedures, and peptide extraction protocols that are compatible with mass spectrometry are described. The detection limits of the various staining procedures and their compatibility with mass ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2005, 301:117-151]

Cited: 20 times

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Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro.

Gunnar Boysen, Cameron O Scarlett, Brenda Temple, Terry P Combs, Natasha L Brooks, Christoph H Borchers, James A Swenberg,

1,3-Butadiene is metabolized mainly by cytochrome P450 2E1 to several epoxides that are considered toxic and carcinogenic. The first step of BD metabolism is oxidation to 1,2-epoxy-3-butene (EB), a reactive metabolite. It has been shown that P450s can be inactivated by covalent binding of reactive metabolites to protein or heme. ... Read more >>

Chem Biol Interact (Chemico-biological interactions)
[2007, 166(1-3):170-175]

Cited: 13 times

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Neuroanatomical development in the absence of PKC phosphorylation of the myristoylated alanine-rich C-kinase substrate (MARCKS) protein.

Cameron O Scarlett, Perry J Blackshear,

The myristoylated alanine-rich C-kinase substrate protein (MARCKS) is a widely expressed target of protein kinase C (PKC) phosphorylation. Disruption of Marcks in mice leads to a number of developmental defects within the central nervous system that are completely prevented by expression of an epitope-tagged wild-type human MARCKS transgene. In the ... Read more >>

Brain Res Dev Brain Res (Brain research. Developmental brain research)
[2003, 144(1):25-42]

Cited: 12 times

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