Full Text Journal Articles by
Author Caizhi Liu

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Anoctamin 1 controls bone resorption by coupling Cl- channel activation with RANKL-RANK signaling transduction.

Weijia Sun, Shuai Guo, Yuheng Li, JianWei Li, Caizhi Liu, Yafei Chen, Xuzhao Wang, Yingjun Tan, Hua Tian, Cheng Wang, Ruikai Du, Guohui Zhong, Sai Shi, Biao Ma, Chang Qu, Jingxuan Fu, Xiaoyan Jin, Dingsheng Zhao, Yong Zhan, Shukuan Ling, Hailong An, Yingxian Li,

Osteoclast over-activation leads to bone loss and chloride homeostasis is fundamental importance for osteoclast function. The calcium-activated chloride channel Anoctamin 1 (also known as TMEM16A) is an important chloride channel involved in many physiological processes. However, its role in osteoclast remains unresolved. Here, we identified the existence of Anoctamin 1 in ... Read more >>

Nat Commun (Nature communications)
[2022, 13(1):2899]

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Comprehensive Transcriptome Profiling of NAFLD- and NASH-Induced Skeletal Muscle Dysfunction.

Mingwei Guo, Liping Xiang, Jing Yao, Jun Zhang, Shuangshuang Zhu, Dongmei Wang, Caizhi Liu, Guoqiang Li, Jiawen Wang, Yuqing Gao, Cen Xie, Xinran Ma, Lingyan Xu, Jian Zhou,

Nonalcoholic fatty liver disease (NAFLD), characterized by extensive triglyceride accumulation in hepatocytes, may progress to nonalcoholic steatohepatitis (NASH) with liver fibrosis and inflammation and increase the risk of cirrhosis, cancer, and death. It has been reported that physical exercise is effective in ameliorating NAFLD and NASH, while skeletal muscle dysfunctions, ... Read more >>

Front Endocrinol (Lausanne) (Frontiers in endocrinology)
[2022, 13:851520]

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