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Author Cai Yun Zhang

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[Effect of moxibustion combined with Guifu Yuhe decoction on the conversion score of idiopathic constitution, serum total lgE and blood EOS in the patients with allergic acne].

Rui-Xue Zhang, Zhen Huang, Qing-Ping Zhang, Ya-Mei Yuan, Peng Zuo, Cai-Yun Zhang, Zheng-Qing Fang, Shu-Jie Hao,

<h4>Objective</h4>To observe the therapeutic effect of moxibustion combined with Guifu Yuhe decoction on allergic acne and the influence on immunologic function in the patients.<h4>Methods</h4>A total of 60 patients with allergic acne were rando-mized into an observation group (30 cases) and a control group (30 cases).Thirty healthy employees were in the ... Read more >>

Zhen Ci Yan Jiu (Zhen ci yan jiu = Acupuncture research)
[2021, 46(9):789-793]

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Comprehensive evaluation of intravitreal conbercept versus half-dose photodynamic therapy for chronic central serous chorioretinopathy.

Jian-Bo Mao, Cai-Yun Zhang, Chen-Yi Liu, Yun Zhang, Jing-Jing Lin, Zhao-Kai Xu, Yi-Qi Chen, Yuan-Yuan Fan, Shi-Xin Zhao, Li-Jun Shen,

<h4>Aim</h4>To compare the safety and efficacy of conbercept intravitreal injection and half-dose photodynamic therapy (PDT) in treating chronic central serous chorioretinopathy (CSC).<h4>Methods</h4>This study was retrospective. Thirty-seven patients (37 eyes) with chronic CSC received conbercept injections while 57 patients (57 eyes) were treated with half-dose PDT. All subjects were followed in ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2021, 14(5):719-724]

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Profile and removal of bisphenol analogues in hospital wastewater, landfill leachate, and municipal wastewater in South China.

Zheng Huang, Jian-Liang Zhao, Cai-Yun Zhang, Wan-Li Rao, Guo-Hai Liang, Hong Zhang, Yue-Hong Liu, Yu-Feng Guan, Hai-Yan Zhang, Guang-Guo Ying,

The presence of bisphenol analogues (BPs) in wastewater can have adverse effects to organisms in the environment. However, knowledge of the wastewater sources, such as hospitals and landfills, as well as the removal of BPs are still limited. Fifteen BPs were investigated in hospital, landfills, and municipal wastewater treatment plants ... Read more >>

Sci Total Environ (The Science of the total environment)
[2021, 790:148269]

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ARHGAP20 Expression Inhibited HCC Progression by Regulating the PI3K-AKT Signaling Pathway.

Gao Liu, Jia Li, Cai-Yun Zhang, Dong-Yang Huang, Ji-Wei Xu,

<h4>Introduction</h4>One of the most common cancers is hepatocellular carcinoma (HCC), which is an aggressive cancer that is associated with high mortality. The expression and role of ARHGAP20 in HCC remain unclear.<h4>Materials and methods</h4>The expression and clinical role of ARHGAP20 were investigated using online databases and HCC samples from Meizhou People's ... Read more >>

J Hepatocell Carcinoma (Journal of hepatocellular carcinoma)
[2021, 8:271-284]

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Characterization of the complete plastid genome of Lysimachia christinae Hance (Primulaceae).

Cai-Yun Zhang, Hai-Fei Yan, Feng-Ying Wang,

<i>Lysimachia christinae</i> Hance is widely distributed in subtropical China at the elevational range from 500-2300 m. The species is an important medicinal herb for treating jaundice, urinary disorders, and the liver. Here, we sequenced and characterized the whole plastid genome of <i>L. christinae</i>. It is 154,810 bp in length, containing two copies ... Read more >>

Mitochondrial DNA B Resour (Mitochondrial DNA. Part B, Resources)
[2021, 6(1):268-270]

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Simultaneous Measurement of Tadehaginoside and its Principal Metabolite in Rats by HPLC–MS/MS and its Application in Pharmacokinetics and Tissue Distribution Study

Cai-Yun Zhang, Ya-Ting Lu, Yin-Feng Tan, Lin Dong, Zhi-Heng Su, Xiao-Po Zhang,

<h4>Background: </h4> Tadehaginoside, an active ingredient isolated from Tadehagi triquetrum L., exhibited various biological activities. However, the pharmacokinetics and tissue-distribution which affects tadehaginoside’s therapeutic actions and application remain elusive.MethodsTo clarify the metabolism of tadehaginoside in vivo , a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established to detect the ... Read more >>

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Ivalin Induces Mitochondria-Mediated Apoptosis Associated with the NF-κB Activation in Human Hepatocellular Carcinoma SMMC-7721 Cells.

Zhuo Han, Fang-Yuan Liu, Shi-Qi Lin, Cai-Yun Zhang, Jia-Hui Ma, Chao Guo, Fu-Juan Jia, Qian Zhang, Wei-Dong Xie, Xia Li,

Ivalin, a natural compound isolated from Carpesium divaricatum, showed excellent microtubule depolymerization activities among human hepatocellular carcinoma in our previous work. Here, we investigated its functions on mitochondria-mediated apoptosis in hepatocellular carcinoma SMMC-7721 cells. DAPI (4',6-diamidino-2-phenylindole) staining, annexin V-fluorexcein isothiocyanate (FITC) apoptosis detection, and western blotting were applied to explore ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2019, 24(20):]

Cited: 1 time

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Actinomycin V Suppresses Human Non-Small-Cell Lung Carcinoma A549 Cells by Inducing G2/M Phase Arrest and Apoptosis via the p53-Dependent Pathway.

Shi-Qi Lin, Fu-Juan Jia, Cai-Yun Zhang, Fang-Yuan Liu, Jia-Hui Ma, Zhuo Han, Wei-Dong Xie, Xia Li,

Actinomycin V, extracted and separated from marine-derived actinomycete <i>Streptomyces sp.</i>, as the superior potential replacement of actinomycin D (which showed defect for its hepatotoxicity) has revealed an ideal effect in the suppression of migration and invasion in human breast cancer cells as referred to in our previous study. In this ... Read more >>

Mar Drugs (Marine drugs)
[2019, 17(10):]

Cited: 6 times

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[Effects of exogenous nitrogen addition on litter decomposition and nutrient release in a temperate desert].

Cai-Yun Zhang, Hong-Mei Zhao, Hui Liu, Wen-Tai Zhang, Yan-Gui Su, Jun-Hui Cheng, Wei-Jun Yang,

A litterbag decomposition experiment was carried out in southern Gurbantunggut Desert, with four nitrogen treatments: N<sub>0</sub>(0 g N·m<sup>-2</sup>·a<sup>-1</sup>), N<sub>5</sub>(5 g N·m<sup>-2</sup>·a<sup>-1</sup>), N<sub>10</sub>(10 g N·m<sup>-2</sup>·a<sup>-1</sup>) and N<sub>20</sub>(20 g N·m<sup>-2</sup>·a<sup>-1</sup>). The aims were to examine the effects of exogenous nitrogen addition on decomposition rate and nutrient release of <i>Tamarix ramosissima</i>, <i>Salicornia europaea</i> ... Read more >>

Ying Yong Sheng Tai Xue Bao (Ying yong sheng tai xue bao = The journal of applied ecology)
[2020, 31(11):3631-3638]

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The anti-inflammatory effect of ent-kaur-15-en-17-al-18-oic acid on lipopolysaccharide-stimulated RAW264.7 cells associated with NF-κB and P38/MAPK pathways.

Cai-Yun Zhang, Shi-Qi Lin, Fang-Yuan Liu, Jia-Hui Ma, Fu-Juan Jia, Zhuo Han, Wei-Dong Xie, Xia Li,

<i>Ent</i>-kaur-15-en-17-al-18-oic acid (LL-3) was demonstrated that it can inhibit LPS-induced nitric oxide (NO) production and macrophage migration, maintain homeostasis of oxidative stress, including increased mitochondrial membrane potential (MMP), decreased levels of reactive oxygen species (ROS) and malondialdehyde (MDA), and maintenance of superoxide dismutase (SOD) and glutathione (GSH) activities and inhibit ... Read more >>

J Asian Nat Prod Res (Journal of Asian natural products research)
[2021, 23(6):570-583]

Cited: 3 times

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Identification of METTL3 as an Adverse Prognostic Biomarker in Hepatocellular Carcinoma.

Gao-Min Liu, Hua-Dong Zeng, Cai-Yun Zhang, Ji-Wei Xu,

<h4>Introduction</h4>N6-methyladenosine (m6A), the most prominent mRNA modification, plays a critical role in many physiological and pathological processes. However, the roles of m6A RNA modification in hepatocellular carcinoma (HCC) remain largely unknown.<h4>Materials and methods</h4>We investigated the mRNA expression and clinical significance of m6A-related genes using data from The Cancer Genome Atlas ... Read more >>

Dig Dis Sci (Digestive diseases and sciences)
[2021, 66(4):1110-1126]

Cited: 14 times

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Identification of a four-gene metabolic signature predicting overall survival for hepatocellular carcinoma.

Gao-Min Liu, Wen-Xuan Xie, Cai-Yun Zhang, Ji-Wei Xu,

While hundreds of consistently altered metabolic genes had been identified in hepatocellular carcinoma (HCC), the prognostic role of them remains to be further elucidated. Messenger RNA expression profiles and clinicopathological data were downloaded from The Cancer Genome Atlas-Liver Hepatocellular Carcinoma and GSE14520 data set from the Gene Expression Omnibus database. ... Read more >>

J Cell Physiol (Journal of cellular physiology)
[2020, 235(2):1624-1636]

Cited: 36 times

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The associations of TNF-α gene polymorphisms with bone mineral density and risk of osteoporosis: A meta-analysis.

Suo-Chao Fu, Ping Wang, Ming-Xing Qi, Jing-Ping Peng, Xiao-Qian Lin, Cai-Yun Zhang, Gui-Xin Zhao, Gong-Hao He,

OBJECTIVE:Fracture is a common consequence of osteoporosis and is associated with high morbidity and mortality. Recently, increasing evidence has suggested that polymorphisms in tumor necrosis factor-α (TNF-α) gene were associated with osteoporosis risk and bone mineral density (BMD), but results remain conflicting. We herein performed a meta-analysis based on evidence ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2019, 22(9):1619-1629]

Cited: 2 times

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STAT3 Targets ERR-α to Promote Epithelial-Mesenchymal Transition, Migration, and Invasion in Triple-Negative Breast Cancer Cells.

Jia-Hui Ma, Jie Qi, Shi-Qi Lin, Cai-Yun Zhang, Fang-Yuan Liu, Wei-Dong Xie, Xia Li,

STAT3 is constitutively activated in many malignant tumor types and plays an important role in multiple aspects of cancer aggressiveness. In this study, we found that estrogen-related receptor α (ERR-α) correlating with STAT3 was highly expressed in triple-negative breast cancer (TNBC) cell lines and tissues, which was associated with both ... Read more >>

Mol Cancer Res (Molecular cancer research : MCR)
[2019, 17(11):2184-2195]

Cited: 10 times

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Key genes associated with diabetes mellitus and hepatocellular carcinoma.

Gao-Min Liu, Hua-Dong Zeng, Cai-Yun Zhang, Ji-Wei Xu,

Accumulating evidence indicates a strong correlation between type 2 diabetes mellitus (T2DM) and hepatocellular carcinoma (HCC), but the underlying pathophysiology is still elusive. We aimed to identify unrecognized but important genes and pathways related to T2DM and HCC by bioinformatic analysis. The GSE64998 and GSE15653 datasets (for T2DM), the GSE121248 ... Read more >>

Pathol Res Pract (Pathology, research and practice)
[2019, 215(11):152510]

Cited: 9 times

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Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma.

Gao-Min Liu, Hua-Dong Zeng, Cai-Yun Zhang, Ji-Wei Xu,

<h4>Background</h4>Hepatocellular carcinoma (HCC) remains a major challenge for public health worldwide. Considering the great heterogeneity of HCC, more accurate prognostic models are urgently needed. To identify a robust prognostic gene signature, we conduct this study.<h4>Materials and methods</h4>Level 3 mRNA expression profiles and clinicopathological data were obtained in The Cancer Genome ... Read more >>

Cancer Cell Int (Cancer cell international)
[2019, 19:138]

Cited: 47 times

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[Effects of Photosynthesis of Submerged Aquatic Plants on CDOM in a Karst Water System: A Case Study from Xueyu Cave, Chongqing, China].

Jia-Xin Fan, Yong-Jun Jiang, Qiu-Fang He, Jia-Nan Wang, Rui-Liang He, Cai-Yun Zhang, Li-Na Ma, Qi-Rong Wang,

Dissolved organic matter (DOM) in karst water is one of the most important carbon sink components, whose origins, distributions, and transport processes are of significance to carbon sink studies. Chromophoric dissolved organic matter (CDOM) can be utilized to express the composition and structural properties of DOM. In this paper, water ... Read more >>

Huan Jing Ke Xue (Huan jing ke xue= Huanjing kexue)
[2019, 40(6):2657-2666]

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Ivalin Inhibits Proliferation, Migration and Invasion by Suppressing Epithelial Mesenchymal Transition in Breast Cancer Cells.

Jia-Hui Ma, Jie Qi, Fang-Yuan Liu, Shi-Qi Lin, Cai-Yun Zhang, Wei-Dong Xie, Hang-Yu Zhang, Xia Li,

Ivalin, an eudesmane-type sesquiterpene compound, was isolated from the Chinese herb Carpesium divaricatum in our chemistry group. In this study, we investigated the anti-migration and anti-invasion activities and underlying mechanisms of Ivalin in breast cancer cells in vitro. Cell viability was evaluated using the MTT assay, Western blotting was used ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2018, 70(8):1330-1338]

Cited: 3 times

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Production of interleukin‑4 in CD133+ cervical cancer stem cells promotes resistance to apoptosis and initiates tumor growth.

Chun-Tao Liu, Ying Xin, Chun-Yan Tong, Bing Li, Hong-Li Bao, Cai-Yun Zhang, Xue-Hui Wang,

The cancer stem cell (CSC) theory suggests that cancer growth and invasion is dictated by the small population of CSCs within the heterogenous tumor. The aim of the present study was to elucidate the cause for chemotherapy failure and the resistance of CSCs to apoptosis. A total of ~2.3% cluster ... Read more >>

Mol Med Rep (Molecular medicine reports)
[2016, 13(6):5068-5076]

Cited: 2 times

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What explains high plant richness in East Asia? Time and diversification in the tribe Lysimachieae (Primulaceae).

Hai-Fei Yan, Cai-Yun Zhang, Arne A Anderberg, Gang Hao, Xue-Jun Ge, John J Wiens,

What causes the disparity in biodiversity among regions is a fundamental question in biogeography, ecology, and evolutionary biology. Evolutionary and biogeographic processes (speciation, extinction, dispersal) directly determine species richness patterns, and can be studied using integrative phylogenetic approaches. However, the strikingly high richness of East Asia relative to other Northern ... Read more >>

New Phytol (The New phytologist)
[2018, 219(1):436-448]

Cited: 7 times

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Protective effects of 3β-angeloyloxy-8β, 10β-dihydroxyeremophila-7(11)-en-12, 8α-lactone on paraquat-induced oxidative injury in SH-SY5Y cells.

Qi-Lin Wang, Chao Guo, Jie Qi, Jia-Hui Ma, Fang-Yuan Liu, Shi-Qi Lin, Cai-Yun Zhang, Wei-Dong Xie, Jing-Jing Zhuang, Xia Li,

3β-Angeloyloxy-8β,10β-dihydroxyeremophila-7(11)-en-12,8α-lactone (FJ1) inhibited effectively paraquat (PQ)-induced injury in SH-SY5Y cells. In this way, FJ1 was shown to reverse the PQ-induced activation of caspase-9 and caspase-3, the increase in Bax/Bcl-2 ratio, and the release of cytochrome c. The mechanism was associated with a reduction of oxidative stress, including the decrease in ... Read more >>

J Asian Nat Prod Res (Journal of Asian natural products research)
[2019, 21(4):364-376]

Cited: 2 times

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Repetitive infusion of levosimendan in patients with chronic heart failure: a meta-analysis.

Gui-Yan Yi, Jun-Xia Li, Jian Zhang, Li-Li Niu, Cai-Yun Zhang,

<h4>Background</h4>Repetitive or intermittent levosimendan infusion is gradually becoming more commonly considered for patients with advanced chronic heart failure. However, previous randomized controlled studies (RCTs) reported conflicting results on the effects of levosimendan when administered repetitively. The aim of this meta-analysis was to generate up-to-date evidence to assess the effect of ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2015, 21:895-901]

Cited: 4 times

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[Retracted] Production of interleukin‑4 in CD133+ cervical cancer stem cells promotes resistance to apoptosis and initiates tumor growth.

Chun-Tao Liu, Ying Xin, Chun-Yan Tong, Bing Li, Hong-Li Bao, Cai-Yun Zhang, Xue-Hui Wang,

Following the publication of this article, an investigation conducted internally within our Department has revealed that the data published in Fig.  5a are not reproducible. Consequently, confidence in the conclusions drawn from the reported results in the paper has been undermined and, as a result, all authors involved have unanimously ... Read more >>

Mol Med Rep (Molecular medicine reports)
[2016, 14(4):4008]

Cited: 0 times

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Characterization of polymorphic microsatellite markers for Primula sikkimensis (Primulaceae) using a 454 sequencing approach.

Chang-Han Li, Yun-Jiao Liu, Cai-Yun Zhang, Hai-Fei Yan, Xue-Jun Ge, Gang Hao,

<h4>Premise of the study</h4>Microsatellite markers from Primula sikkimensis (Primulaceae) were developed for testing deep lineage divergence and speciation events.<h4>Methods and results</h4>A total of 3112 microsatellites were identified from 61,755 unique reads though 454 pyrosequencing technology. Twenty-nine microsatellite loci were selected for PCR amplification and polymorphic analyses. Among the 29 tested ... Read more >>

Appl Plant Sci (Applications in plant sciences)
[2016, 4(7):]

Cited: 0 times

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Complete plastid genome sequence of Primula sinensis (Primulaceae): structure comparison, sequence variation and evidence for accD transfer to nucleus.

Tong-Jian Liu, Cai-Yun Zhang, Hai-Fei Yan, Lu Zhang, Xue-Jun Ge, Gang Hao,

Species-rich genus Primula L. is a typical plant group with which to understand genetic variance between species in different levels of relationships. Chloroplast genome sequences are used to be the information resource for quantifying this difference and reconstructing evolutionary history. In this study, we reported the complete chloroplast genome sequence ... Read more >>

PeerJ (PeerJ)
[2016, 4:e2101]

Cited: 15 times

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