Full Text Journal Articles by
Author C Owens

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Leptomeningeal Relapse of Embryonal Rhabdomyosarcoma after 15 years.

S Chew, J P Gleeson, A McCarthy, G A Watson, R O'Dwyer, S Nicholson, M Capra, C Owens, M McDermott, P Daly, C Grant,

Aim Rhabdomyosarcoma (RMS) is the most common malignant soft tissue tumour of childhood. We present the case of a late relapse of RMS to the leptomeninges after 15 years. Methods A 20 year old male presented with a 3 week history of headaches and nausea. He previously had RMS of ... Read more >>

Ir Med J (Irish medical journal)
[2020, 112(10):1026]

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Non-radiologist-performed point-of-care ultrasonography in paediatrics - European Society of Paediatric Radiology position paper.

Rick R van Rijn, Samuel Stafrace, Owen J Arthurs, Karen Rosendahl, ,

Non-radiologist point-of-care ultrasonography (US) is increasingly implemented in paediatric care because it is believed to facilitate a timely diagnosis, such as in ascites or dilated renal pelvicalyceal systems, and can be used to guide interventional procedures. To date, all policy statements have been published by non-radiologic societies. The European Society ... Read more >>

Pediatr Radiol (Pediatric radiology)
[2020, :]

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A Study to Evaluate the Need for Comminution in the Preparation of Food Materials for Testing of Listeria monocytogenes, Staphylococcus Species, and Generic Escherichia coli.

Patricia Hanson, Nicole Mitchell, S Brian Caudle, Lyndsey Caulkins, Cameron Owens, Patty Lewandowski, Diane Pickett,

BACKGROUND:Comminution reduces the sampling error arising from distributional heterogeneity of the target contaminant/target analyte in the material, facilitating the selection of a more representative test portion. A laboratory sampling method incorporating comminution prior to selection of the test portion (Sampling Method B) was compared to current sampling methods that used ... Read more >>

J AOAC Int (Journal of AOAC International)
[2020, 103(6):1639-1645]

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Pharmacists' Willingness to Provide Coronavirus Disease (COVID-19) Services and the Needs to Support COVID-19 Testing, Management, and Prevention.

Elaine Nguyen, Christopher T Owens, Tayler Daniels, Jeremy Boyle, Renee F Robinson,

The need for increased testing is pivotal in the response to the coronavirus disease (COVID-19) pandemic. Recently, through the Public Readiness and Emergency Preparedness (PREP) Act, pharmacists were given the ability to order and administer COVID-19 tests, giving them a better opportunity to engage in the pandemic response across the ... Read more >>

J Community Health (Journal of community health)
[2020, :]

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Georgia Rural Hospital Tax Credit: Perspectives of Rural Health Executives.

Samuel T Opoku, Bettye A Apenteng, Charles Owens, Linda Kimsey, Angie Peden, Imaobong Ekpo, William A Mase, Emmanuel Akowuah,

PURPOSE:In 2016, Georgia implemented a rural hospital tax credit program through a legislative mandate that allows individuals and corporations to donate to qualifying rural hospitals in exchange for state income tax credit. The study examines the importance, success, and challenges of the program, and opportunities for improvement, from the perspective ... Read more >>

J Rural Health (The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association)
[2020, :]

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Development and validation of an age-scalable cardiac model with substructures for dosimetry in late-effects studies of childhood cancer survivors.

Suman Shrestha, Aashish C Gupta, James E Bates, Choonsik Lee, Constance A Owens, Bradford S Hoppe, Louis S Constine, Susan A Smith, Ying Qiao, Rita E Weathers, Yutaka Yasui, Laurence E Court, Arnold C Paulino, Chelsea C Pinnix, Stephen F Kry, David S Followill, Gregory T Armstrong, Rebecca M Howell,

BACKGROUND AND PURPOSE:Radiation therapy is a risk factor for late cardiac disease in childhood cancer survivors. Several pediatric cohort studies have established whole heart dose and dose-volume response models. Emerging data suggest that dose to cardiac substructures may be more predictive than whole heart metrics. In order to develop substructure ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2020, :]

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Aspirin Discontinuation in Patients Requiring Oral Anticoagulation Undergoing Percutaneous Coronary Intervention, The Role of Procedural Complexity.

Mohammad Alkhalil, Michael Shahmohammadi, Mark S Spence, Colum G Owens,

BACKGROUND:The prognostic role of procedural complexity when discontinuing aspirin in patients on oral anticoagulation undergoing percutaneous coronary intervention (PCI) has never been studied. METHODS:Ischaemic events were compared in 256 consecutive patients according to procedural complexity and aspirin on discharge. PCI complexity was defined according to the high-risk features for ischaemic ... Read more >>

Cardiovasc Drugs Ther (Cardiovascular drugs and therapy)
[2020, 34(5):659-662]

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An observational study of the lung clearance index throughout childhood in cystic fibrosis: early years matter.

Gwyneth Davies, Sanja Stanojevic, Emma Raywood, Julie A Duncan, Janet Stocks, Sooky Lum, Andrew Bush, Laura Viviani, Angie Wade, Alistair Calder, Catherine M Owens, Christophe Goubau, Siobhán B Carr, Cara J Bossley, Caroline Pao, Paul Aurora, ,

Eur Respir J (The European respiratory journal)
[2020, 56(4):]

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Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: A report from the Innovative Therapies for Children with Cancer (ITCC) consortium.

Alba Rubio-San-Simón, Nicolas André, Maria Giuseppina Cefalo, Isabelle Aerts, Alicia Castañeda, Sarah Benezech, Guy Makin, Natasha van Eijkelenburg, Karsten Nysom, Lynley Marshall, Marion Gambart, Raquel Hladun, Claudia Rossig, Luca Bergamaschi, Franca Fagioli, Ben Carpenter, Stephane Ducassou, Cormac Owens, Ingrid Øra, Antonio Juan Ribelles, Bram De Wilde, Pilar Guerra-García, Marion Strullu, Carmelo Rizzari, Torben Ek, Simone Hettmer, Nicolas U Gerber, Christine Rawlings, Manuel Diezi, Sauli Palmu, Antonio Ruggiero, Jaime Verdú, Teresa de Rojas, Gilles Vassal, Birgit Geoerger, Lucas Moreno, Francisco Bautista,

INTRODUCTION:Data regarding real-world impact on cancer clinical research during COVID-19 are scarce. We analysed the impact of the COVID-19 pandemic on the conduct of paediatric cancer phase I-II trials in Europe through the experience of the Innovative Therapies for Children with Cancer (ITCC). METHODS:A survey was sent to all ITCC-accredited ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2020, 141:82-91]

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Use of e-Cigarettes and Development of Respiratory Conditions in Women of Childbearing Age.

Tarang Parekh, Constance Owens, Kathryn Fay, Joseph Phillips, Panagiota Kitsantas,

OBJECTIVE:Women of childbearing age are encouraged not to smoke because of well-documented adverse health outcomes. This study examines the association between e-cigarette use and respiratory conditions (asthma and chronic obstructive pulmonary disease [COPD]) among women of childbearing age. METHODS:The study used data from the Behavioral Risk Factor Surveillance System 2016-2017. ... Read more >>

South Med J (Southern medical journal)
[2020, 113(10):488-494]

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Outcomes in patients with DLBCL treated with commercial CAR T cells compared with alternate therapies.

David Sermer, Connie Batlevi, M Lia Palomba, Gunjan Shah, Richard J Lin, Miguel-Angel Perales, Michael Scordo, Parastoo Dahi, Martina Pennisi, Aishat Afuye, Mari Lynne Silverberg, Caleb Ho, Jessica Flynn, Sean Devlin, Philip Caron, Audrey Hamilton, Paul Hamlin, Steven Horwitz, Erel Joffe, Anita Kumar, Matthew Matasar, Ariela Noy, Colette Owens, Alison Moskowitz, David Straus, Gottfried von Keudell, Ildefonso Rodriguez-Rivera, Lorenzo Falchi, Andrew Zelenetz, Joachim Yahalom, Anas Younes, Craig Sauter,

The prognosis of patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) is poor. Chimeric antigen receptor (CAR) T-cell therapy has been approved for R/R DLBCL after 2 prior lines of therapy based on data from single-arm phase 2 trials, with complete responses (CRs) in 40% to 60% ... Read more >>

Blood Adv (Blood advances)
[2020, 4(19):4669-4678]

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A Remembrance of John B. McGinty MD (1930-2019).

Colleen T Owens,

Clin Orthop Relat Res (Clinical orthopaedics and related research)
[2020, 478(10):2410-2411]

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Graduate Student Literature Review: Potential mechanisms of interaction between bacteria and the reproductive tract of dairy cattle.

C E Owens, K M Daniels, A D Ealy, K F Knowlton, R R Cockrum,

Although the presence of bacteria has been characterized throughout the reproductive tracts of multiple species, how these bacteria may interact with the host has yet to be described. Previous reviews have described how pathogenic bacteria interact with the reproductive tract to cause infections such as metritis. This review aimed to ... Read more >>

J Dairy Sci (Journal of dairy science)
[2020, 103(11):10951-10960]

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A pan-cancer analysis of PD-L1 immunohistochemistry and gene amplification, tumor mutation burden and microsatellite instability in 48,782 cases.

Richard S P Huang, James Haberberger, Eric Severson, Daniel L Duncan, Amanda Hemmerich, Claire Edgerly, Naomi Lynn Ferguson, Erik Williams, Julia Elvin, Jo-Anne Vergilio, Jonathan Keith Killian, Douglas I Lin, Julie Tse, Matthew Hiemenz, Clarence Owens, Natalie Danziger, Priti S Hegde, Jeffrey Venstrom, Brian Alexander, Jeffrey S Ross, Shakti H Ramkissoon,

PD-L1 immunohistochemistry (IHC) currently has the most Food and Drug Administration (FDA) approvals as a companion diagnostic (CDx) for immunotherapies in specific tumor types; however, multiple other immunotherapy biomarkers exist. We performed this study to examine and report the prevalence of PD-L1 expression in a wide variety of tumor types ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2020, :]

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Two Years of Improved Neurological Function With Nusinersen in a 48-Year-Old Patient With Spinal Muscular Atrophy Type 3.

Jaimin S Shah, Devon I Rubin, Elliot L Dimberg, Christina R Owens, Angelica R Gicalone, Gleydiane De Oliveira, Björn E Oskarsson,

INTRODUCTION:Nusinersen antisense oligonucleotide infusions have been shown to be effective in the treatment spinal muscular atrophy. The majority of the evidence has been collected in young type 1 and type 2 patients, and evidence of efficacy in adult patients is limited. CASE REPORT:A 48-year-old woman with spinal muscular atrophy type ... Read more >>

Neurologist (The neurologist)
[2020, 25(5):141-143]

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Thoracic imaging of coronavirus disease 2019 (COVID-19) in children: a series of 91 cases.

Pablo Caro-Dominguez, Susan Cheng Shelmerdine, Seema Toso, Aurelio Secinaro, Paolo Toma, Maria Beatrice Damasio, María Navallas, Lucia Riaza-Martin, David Gomez-Pastrana, Maryam Ghadimi Mahani, Sarah M Desoky, Carlos F Ugas Charcape, Judith Almanza-Aranda, Maria Elena Ucar, Jovan Lovrenski, Sureyya Burcu Gorkem, Efthymia Alexopoulou, Pierluigi Ciet, Joost van Schuppen, Hubert Ducou le Pointe, Hyun Woo Goo, Christian J Kellenberger, Maria Raissaki, Catherine M Owens, Franz Wolfgang Hirsch, Rick R van Rijn, ,

BACKGROUND:Pulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic. OBJECTIVE:To collect paediatric COVID-19 cases worldwide and to summarize both clinical and imaging findings in children who tested positive on polymerase chain reaction testing for SARS-CoV-2. MATERIALS AND METHODS:Data ... Read more >>

Pediatr Radiol (Pediatric radiology)
[2020, 50(10):1354-1368]

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The Reply.

Mohammad Alkhalil, Colum G Owens, Mark S Spence,

Am J Med (The American journal of medicine)
[2020, 133(8):e447]

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Clinical Characteristics and Outcomes of Extranodal Stage I Diffuse Large B Cell Lymphoma in The Rituximab-Era.

Sabela Bobillo, Erel Joffe, Jessica A Lavery, David Sermer, Paola Ghione, Ariela Noy, Philip Charles Caron, Audrey May Hamilton, Paul A Hamlin, Steven M Horwitz, Anita Kumar, Matthew J Matasar, Alison J Moskowitz, Colette Owens, Maria Lia Palomba, Connie Batlevi, David J Straus, Gottfried von Keudell, Andrew D Zelenetz, Joachim Yahalom, Ahmet Dogan, Venkatraman E Seshan, Anas Younes,

This retrospective study aimed to better define the characteristics and outcomes of extranodal stage I DLBCL in the rituximab era. Patients diagnosed with stage I DLBCL from 2001-2015 treated with rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP) or R-CHOP-like regimens with or without radiation (RT) were included. We identified 1955 patients ... Read more >>

Blood (Blood)
[2020, :]

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Prespecified Risk Criteria Facilitate Adequate Discharge and Long-Term Outcomes After Transfemoral Transcatheter Aortic Valve Implantation.

Mark S Spence, Jan Baan, Fortunato Iacovelli, Gian Luca Martinelli, Douglas F Muir, Francesco Saia, Alessandro Santo Bortone, Cameron G Densem, Colum G Owens, Frank van der Kley, Marije Vis, Martijn S van Mourik, Giuliano Costa, Lenka Sykorova, Claudia M Lüske, Cornelia Deutsch, Jana Kurucova, Martin Thoenes, Peter Bramlage, Corrado Tamburino, Marco Barbanti,

Background Despite the availability of guidelines for the performance of transcatheter aortic valve implantation (TAVI), current treatment pathways vary between countries and institutions, which impact on the mean duration of postprocedure hospitalization. Methods and Results This was a prospective, multicenter registry of 502 patients to validate the appropriateness of discharge ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2020, 9(15):e016990]

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A review on the woody breast condition, detection methods, and product utilization in the contemporary poultry industry.

Juan P Caldas-Cueva, Casey M Owens,

In recent years, the global poultry industry has been facing increasing and challenging myopathies such as the woody breast (WB) condition that has caused significant economic losses. Even though the etiological causes of WB myopathy are still unknown or partially understood, the intensive genetic selection for rapid-growth rates and high ... Read more >>

J Anim Sci (Journal of animal science)
[2020, 98(8):]

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Influence of Surgical Excision on the Survival of Patients With Stage 4 High-Risk Neuroblastoma: A Report From the HR-NBL1/SIOPEN Study.

Keith Holmes, Ulrike Pötschger, Andrew D J Pearson, Sabine Sarnacki, Giovanni Cecchetto, Javier Gomez-Chacon, Roly Squire, Enrique Freud, Adam Bysiek, Lucas E Matthyssens, Martin Metzelder, Tom Monclair, Jakob Stenman, Michal Rygl, Lars Rasmussen, Jean-Marc Joseph, Sabine Irtan, Stefano Avanzini, Jan Godzinski, Kristin Björnland, Martin Elliott, Roberto Luksch, Victoria Castel, Shifra Ash, Walentyna Balwierz, Geneviève Laureys, Ellen Ruud, Vassilios Papadakis, Josef Malis, Cormac Owens, Henrik Schroeder, Maja Beck-Popovic, Toby Trahair, Ana Forjaz de Lacerda, Peter F Ambros, Mark N Gaze, Kieran McHugh, Dominique Valteau-Couanet, Ruth Lydia Ladenstein, ,

PURPOSE:To evaluate the impact of surgeon-assessed extent of primary tumor resection on local progression and survival in patients in the International Society of Pediatric Oncology Europe Neuroblastoma Group High-Risk Neuroblastoma 1 trial. PATIENTS AND METHODS:Patients recruited between 2002 and 2015 with stage 4 disease > 1 year or stage 4/4S ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2020, 38(25):2902-2915]

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Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.

Lucas Moreno, Giuseppe Barone, Steven G DuBois, Jan Molenaar, Matthias Fischer, Johannes Schulte, Angelika Eggert, Gudrun Schleiermacher, Frank Speleman, Louis Chesler, Birgit Geoerger, Michael D Hogarty, Meredith S Irwin, Nick Bird, Guy B Blanchard, Sean Buckland, Hubert Caron, Susan Davis, Bram De Wilde, Hedwig E Deubzer, Emmy Dolman, Martin Eilers, Rani E George, Sally George, Štěrba Jaroslav, John M Maris, Lynley Marshall, Melinda Merchant, Peter Mortimer, Cormac Owens, Anna Philpott, Evon Poon, Jerry W Shay, Roberto Tonelli, Dominique Valteau-Couanet, Gilles Vassal, Julie R Park, Andrew D J Pearson,

Only one class of targeted agents (anti-GD2 antibodies) has been incorporated into front-line therapy for neuroblastoma since the 1980s. The Neuroblastoma New Drug Development Strategy (NDDS) initiative commenced in 2012 to accelerate the development of new drugs for neuroblastoma. Advances have occurred, with eight of nine high-priority targets being evaluated ... Read more >>

Eur. J. Cancer (European journal of cancer (Oxford, England : 1990))
[2020, 136:52-68]

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In vivo collagen and mixed muscle protein turnover in 2 meat-type broiler strains in relation to woody breast myopathy.

Pramir Maharjan, Jordan Weil, Antonio Beitia, Nawin Suesuttajit, Katie Hilton, Justina Caldas, Cole Umberson, Diego Martinez, Casey M Owens, Craig Coon,

Two meat-type broiler strains, strain A and strain B, were reared in floor pens (25 birds/pen; 45 pens/strain) for pectoralis (P) major collagen and mixed muscle protein turnover (PT) study from 0-56 D using primary breeder nutrition and husbandry guidelines. Forty broilers (n = 10/strain for collagen PT; n = 10/strain for ... Read more >>

Poult Sci (Poultry science)
[2020, 99(10):5055-5064]

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Extra copies of MYC, BCL2, and BCL6 and outcome in patients with diffuse large B-cell lymphoma.

David Sermer, Sabela Bobillo, Ahmet Dogan, Yanming Zhang, Venkatraman Seshan, Jessica A Lavery, Connie Batlevi, Philip Caron, Audrey Hamilton, Paul Hamlin, Steven Horwitz, Erel Joffe, Anita Kumar, Matthew Matasar, Ariela Noy, Colette Owens, Alison Moskowitz, M Lia Palomba, David Straus, Gottfried von Keudell, Ildefonso Rodriguez-Rivera, Lorenzo Falchi, Andrew Zelenetz, Joachim Yahalom, Anas Younes,

High-grade B-cell lymphoma (HGBL) with translocations involving MYC and BCL2 or BCL6 comprises ∼10% of cases of diffuse large B-cell lymphoma (DLBCL) and carries a poor prognosis. The incidence, prognosis, and optimal therapy for DLBCL harboring extra copies of the genes MYC, BCL2, and BCL6, rather than their genetic translocations, ... Read more >>

Blood Adv (Blood advances)
[2020, 4(14):3382-3390]

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Predictors of response for elagolix with add-back therapy in women with heavy menstrual bleeding associated with uterine fibroids.

Ayman Al-Hendy, Linda Bradley, Charlotte D Owens, Hui Wang, Kurt T Barnhart, Eve Feinberg, William D Schlaff, Elizabeth E Puscheck, Alice Wang, Veronica Gillispie, Sandra Hurtado, Ozgul Muneyyirci-Delale, David F Archer, Bruce R Carr, James A Simon, Elizabeth A Stewart,

BACKGROUND:Uterine fibroids are one of the most common neoplasms found among women globally, with a prevalence of approximately 11 million women in the United States alone. The morbidity of this common disease is significant because it is the leading cause of hysterectomy and causes significant functional impairment for women of ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2020, :]

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