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Prevalence of SARS-Cov-2 Antibodies in Emergency Medicine Providers

Ralph C. Wang, Charles E. Murphy, Aaron E. Kornblith, Theodore Kurtz, Michael A. Kohn,

Ann Emerg Med (Annals of emergency medicine)
[2021, :]

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Opposing associations of depression with sexual behaviour: implications for epidemiological investigation among gay, bisexual and other men who have sex with men.

Ada R Miltz, Alison J Rodger, Andrew N Phillips, Janey Sewell, Simon Edwards, Sris Allan, Lorraine Sherr, Anne M Johnson, William J Burman, Fiona C Lampe, ,

<h4>Objective</h4>The aim of this report is to investigate the nature of the relationship between depression and condomless sex (CLS) among gay, bisexual and other men who have sex with men (GBMSM).<h4>Methods</h4>Data are from the Antiretrovirals, Sexual Transmission Risk and Attitude (ASTRA) study of people living with HIV and attending one ... Read more >>

Sex Transm Infect (Sexually transmitted infections)
[2021, :]

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Temporal proximity to the elicitation of curiosity is key for enhancing memory for incidental information.

Charlotte Murphy, Vera Dehmelt, Andrew P Yonelinas, Charan Ranganath, Matthias J Gruber,

Curiosity states benefit memory for target information, but also incidental information presented during curiosity states. However, it is not known whether incidental curiosity-enhanced memory depends on when incidental information during curiosity states is encountered. Here, participants incidentally encoded unrelated face images at different time points while they anticipated answers to ... Read more >>

Learn Mem (Learning & memory (Cold Spring Harbor, N.Y.))
[2021, 28(2):34-39]

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Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes.

P Elliott Miller, Fouad Chouairi, Alexander Thomas, Yukiko Kunitomo, Faisal Aslam, Maureen E Canavan, Christa Murphy, Krishna Daggula, Thomas Metkus, Saraschandra Vallabhajosyula, Anthony Carnicelli, Jason N Katz, Nihar R Desai, Tariq Ahmad, Eric J Velazquez, Joseph Brennan,

Background Several studies have shown improved outcomes in closed compared with open medical and surgical intensive care units. However, very little is known about the ideal organizational structure in the modern cardiac intensive care unit (CICU). Methods and Results We retrospectively reviewed consecutive unique admissions (n=3996) to our tertiary care ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2021, :e018182]

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Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine

Robert Wichers, James Findon, Auke Jelsma, Vincent Giampietro, Vladimira Stoencheva, Dene Roberton, Clodagh Murphy, Sarah Blainey, Grainne McAlonan, Christine Ecker, Katya Rubia, Declan Murphy, Eileen Daly,

<h4>Background: </h4> : Autism spectrum disorder (ASD) is associated with deficits in executive functioning (EF), and these have been suggested to contribute to core as well as co-occuring psychiatric symptoms. The biological basis of these deficits is unknown but may include the serotonergic system, which is involved in both regulating ... Read more >>

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GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

Roger Jie Liang, Samuel Taylor, Navid Nahiyaan, Junho Song, Charles Murphy, Ezequiel Dantas, Shuyuan Cheng, Ting-Wei Hsu, Shakti Ramsamooj, Rahul Grover, Seo-Kyoung Hwang, Bryan Ngo, Lewis Cantley, Kyu Rhee, Marcus DaSilva Goncalves,

<h4>Background: </h4> Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that acquire the ability to metabolize fructose have a fitness advantage over their neighboring cells, but the proteins that mediate fructose metabolism ... Read more >>

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A Pilot Study of Gut-Brain Signaling After Octreotide Therapy for Unintentional Weight Loss After Esophagectomy.

Conor F Murphy, Nicholas Stratford, Neil G Docherty, Brendan Moran, Jessie A Elliott, Marie-Louise Healy, Jason P McMorrow, Narayanasamy Ravi, Anthony P Goldstone, John V Reynolds, Carel W le Roux,

<h4>Background</h4>Recurrence-free patients after esophageal cancer surgery face long-term nutritional consequences, occurring in the context of an exaggerated postprandial gut hormone response. Acute gut hormone suppression influences brain reward signaling and eating behavior. This study aimed to suppress gut hormone secretion and characterize reward responses and eating behavior among postesophagectomy patients ... Read more >>

J Clin Endocrinol Metab (The Journal of clinical endocrinology and metabolism)
[2021, 106(1):e204-e216]

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Beware the quiet eye: primary vitreoretinal lymphoma masquerading as posterior uveitis.

Talal Almas, Kirk Aj Stephenson, Maryam Ehtesham, Conor C Murphy,

BMJ Case Rep (BMJ case reports)
[2020, 13(12):]

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Horizontal and vertical transmission of transgenerational memories via the Cer1 transposon

Rebecca Moore, Rachel Kaletsky, Chen Lesnik, Vanessa Cota, Edith Blackman, Lance Parsons, Zemer Gitai, Coleen Murphy,

Animals face both external and internal dangers: pathogens threaten from the environment, and unstable genomic elements threaten from within. Previously, we discovered that C. elegans protects itself from pathogens by “reading” bacterial small RNAs and using this information to both induce avoidance and transmit memories for several generations. Here we ... Read more >>

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Alaska backcountry expeditionary hunting promotes rapid improvements in metabolic biomarkers in healthy males and females.

Melynda S Coker, Kaylee Ladd, Carl J Murphy, Brent C Ruby, Timothy C Shriver, Dale A Schoeller, Bradley R Newcomer, Terry Bateman, Larry Bartlett, Robert H Coker,

We have previously reported negative energy balance and health benefits during an Alaska backcountry expeditionary hunting (ABEH) immersion in two males. The purpose of our present study was to increase the number of participants, include females, and evaluate macronutrient intake and serum lipids. Four men (age: 46 ± 6 year, BMI: 26 ± 1 kg/m<sup>2</sup> ) ... Read more >>

Physiol Rep (Physiological reports)
[2021, 9(1):e14682]

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Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.

, , , , , , Yash Patel, Nadine Parker, Jean Shin, Derek Howard, Leon French, Sophia I Thomopoulos, Elena Pozzi, Yoshinari Abe, Christoph Abé, Alan Anticevic, Martin Alda, Andre Aleman, Clara Alloza, Silvia Alonso-Lana, Stephanie H Ameis, Evdokia Anagnostou, Andrew A McIntosh, Celso Arango, Paul D Arnold, Philip Asherson, Francesca Assogna, Guillaume Auzias, Rosa Ayesa-Arriola, Geor Bakker, Nerisa Banaj, Tobias Banaschewski, Cibele E Bandeira, Alexandr Baranov, Núria Bargalló, Claiton H D Bau, Sarah Baumeister, Bernhard T Baune, Mark A Bellgrove, Francesco Benedetti, Alessandro Bertolino, Premika S W Boedhoe, Marco Boks, Irene Bollettini, Caterina Del Mar Bonnin, Tiana Borgers, Stefan Borgwardt, Daniel Brandeis, Brian P Brennan, Jason M Bruggemann, Robin Bülow, Geraldo F Busatto, Sara Calderoni, Vince D Calhoun, Rosa Calvo, Erick J Canales-Rodríguez, Dara M Cannon, Vaughan J Carr, Nicola Cascella, Mara Cercignani, Tiffany M Chaim-Avancini, Anastasia Christakou, David Coghill, Annette Conzelmann, Benedicto Crespo-Facorro, Ana I Cubillo, Kathryn R Cullen, Renata B Cupertino, Eileen Daly, Udo Dannlowski, Christopher G Davey, Damiaan Denys, Christine Deruelle, Annabella Di Giorgio, Erin W Dickie, Danai Dima, Katharina Dohm, Stefan Ehrlich, Benjamin A Ely, Tracy Erwin-Grabner, Thomas Ethofer, Damien A Fair, Andreas J Fallgatter, Stephen V Faraone, Mar Fatjó-Vilas, Jennifer M Fedor, Kate D Fitzgerald, Judith M Ford, Thomas Frodl, Cynthia H Y Fu, Janice M Fullerton, Matt C Gabel, David C Glahn, Gloria Roberts, Tinatin Gogberashvili, Jose M Goikolea, Ian H Gotlib, Roberto Goya-Maldonado, Hans J Grabe, Melissa J Green, Eugenio H Grevet, Nynke A Groenewold, Dominik Grotegerd, Oliver Gruber, Patricia Gruner, Amalia Guerrero-Pedraza, Raquel E Gur, Ruben C Gur, Shlomi Haar, Bartholomeus C M Haarman, Jan Haavik, Tim Hahn, Tomas Hajek, Benjamin J Harrison, Neil A Harrison, Catharina A Hartman, Heather C Whalley, Dirk J Heslenfeld, Derrek P Hibar, Eva Hilland, Yoshiyuki Hirano, Tiffany C Ho, Pieter J Hoekstra, Liesbeth Hoekstra, Sarah Hohmann, L E Hong, Cyril Höschl, Marie F Høvik, Fleur M Howells, Igor Nenadic, Maria Jalbrzikowski, Anthony C James, Joost Janssen, Fern Jaspers-Fayer, Jian Xu, Rune Jonassen, Georgii Karkashadze, Joseph A King, Tilo Kircher, Matthias Kirschner, Kathrin Koch, Peter Kochunov, Gregor Kohls, Kerstin Konrad, Bernd Krämer, Axel Krug, Jonna Kuntsi, Jun Soo Kwon, Mikael Landén, Nils I Landrø, Luisa Lazaro, Irina S Lebedeva, Elisabeth J Leehr, Sara Lera-Miguel, Klaus-Peter Lesch, Christine Lochner, Mario R Louza, Beatriz Luna, Astri J Lundervold, Frank P MacMaster, Luigi A Maglanoc, Charles B Malpas, Maria J Portella, Rachel Marsh, Fiona M Martyn, David Mataix-Cols, Daniel H Mathalon, Hazel McCarthy, Colm McDonald, Genevieve McPhilemy, Susanne Meinert, José M Menchón, Luciano Minuzzi, Philip B Mitchell, Carmen Moreno, Pedro Morgado, Filippo Muratori, Clodagh M Murphy, Declan Murphy, Benson Mwangi, Leila Nabulsi, Akiko Nakagawa, Takashi Nakamae, Leyla Namazova, Janardhanan Narayanaswamy, Neda Jahanshad, Danai D Nguyen, Rosa Nicolau, Ruth L O'Gorman Tuura, Kirsten O'Hearn, Jaap Oosterlaan, Nils Opel, Roel A Ophoff, Bob Oranje, Victor Ortiz García de la Foz, Bronwyn J Overs, Yannis Paloyelis, Christos Pantelis, Mara Parellada, Paul Pauli, Maria Picó-Pérez, Felipe A Picon, Fabrizio Piras, Federica Piras, Kerstin J Plessen, Edith Pomarol-Clotet, Adrian Preda, Olga Puig, Yann Quidé, Joaquim Radua, J Antoni Ramos-Quiroga, Paul E Rasser, Lisa Rauer, Janardhan Reddy, Ronny Redlich, Andreas Reif, Liesbeth Reneman, Jonathan Repple, Alessandra Retico, Vanesa Richarte, Anja Richter, Pedro G P Rosa, Katya K Rubia, Ryota Hashimoto, Matthew D Sacchet, Raymond Salvador, Javier Santonja, Kelvin Sarink, Salvador Sarró, Theodore D Satterthwaite, Akira Sawa, Ulrich Schall, Peter R Schofield, Anouk Schrantee, Jochen Seitz, Mauricio H Serpa, Esther Setién-Suero, Philip Shaw, Devon Shook, Tim J Silk, Kang Sim, Schmitt Simon, Helen Blair Simpson, Aditya Singh, Antonin Skoch, Norbert Skokauskas, Jair C Soares, Noam Soreni, Carles Soriano-Mas, Gianfranco Spalletta, Filip Spaniel, Stephen M Lawrie, Emily R Stern, S Evelyn Stewart, Yoichiro Takayanagi, Henk S Temmingh, David F Tolin, David Tomecek, Diana Tordesillas-Gutiérrez, Michela Tosetti, Anne Uhlmann, Therese van Amelsvoort, Nic J A van der Wee, Steven J A van der Werff, Neeltje E M van Haren, Guido A van Wingen, Alasdair Vance, Javier Vázquez-Bourgon, Daniela Vecchio, Ganesan Venkatasubramanian, Eduard Vieta, Oscar Vilarroya, Yolanda Vives-Gilabert, Aristotle N Voineskos, Henry Völzke, Georg G von Polier, Esther Walton, Thomas W Weickert, Cynthia Shannon Weickert, Andrea S Weideman, Katharina Wittfeld, Daniel H Wolf, Mon-Ju Wu, T T Yang, Kun Yang, Yuliya Yoncheva, Je-Yeon Yun, Yuqi Cheng, Marcus V Zanetti, Georg C Ziegler, Barbara Franke, Martine Hoogman, Jan K Buitelaar, Daan van Rooij, Ole A Andreassen, Christopher R K Ching, Dick J Veltman, Lianne Schmaal, Dan J Stein, Odile A van den Heuvel, Jessica A Turner, Theo G M van Erp, Zdenka Pausova, Paul M Thompson, Tomáš Paus,

<h4>Importance</h4>Large-scale neuroimaging studies have revealed group differences in cortical thickness across many psychiatric disorders. The underlying neurobiology behind these differences is not well understood.<h4>Objective</h4>To determine neurobiologic correlates of group differences in cortical thickness between cases and controls in 6 disorders: attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), ... Read more >>

JAMA Psychiatry (JAMA psychiatry)
[2021, 78(1):47-63]

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Major obstetric haemorrhage: Incidence, management and quality of care in Irish maternity units.

Richard A Greene, Joye McKernan, Edel Manning, Paul Corcoran, Bridgette Byrne, Sharon Cooley, Deirdre Daly, Anne Fallon, Mary Higgins, Claire Jones, Ita Kinsella, Cliona Murphy, Janet Murphy, Meabh Ni Bhuinneain, ,

<h4>Objective</h4>To assess major obstetric haemorrhage incidence, management and quality of care in Irish maternity units.<h4>Design</h4>In collaboration with Irish maternity units the National Perinatal Epidemiology Centre (Leitao et al., 2020) carried out a national clinical audit and surveillance of major obstetric haemorrhage (MOH).<h4>Methods</h4>MOH was defined as blood loss of at least ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 257:114-120]

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Uterine Fibroid in a 16-year-old adolescent managed with a fertility sparing approach: A Case Report and Review of the Literature.

Courtney A Murphy, Oxana Zarudskaya, Carmen Kakish, Dani Zoorob, Sonyoung Seo-Patel,

<h4>Background</h4>Uterine fibroids are the most common benign tumor of the uterus in adult women. However, it is exceedingly rare in adolescent girls.<h4>Case</h4>A 16-year-old girl presented with severe anemia and abnormal uterine bleeding. MRI of the pelvis demonstrated a 9-cm mass within the uterus concerning for leiomyoma or leiomyosarcoma. A fertility ... Read more >>

J Pediatr Adolesc Gynecol (Journal of pediatric and adolescent gynecology)
[2020, :]

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Racial and ethnic disparities in germline genetic testing of patients with young-onset colorectal cancer.

Pooja Dharwadkar, Garrett Greenan, Elena M Stoffel, Ezra Burstein, Sara Pirzadeh-Miller, Sayoni Lahiri, Caitlin Mauer, Amit G Singal, Caitlin C Murphy,

<h4>Background and aims</h4>Up to 20% of younger patients (age <50 years) diagnosed with colorectal cancer (CRC) have germline mutations in cancer susceptibility genes. Germline genetic testing may guide clinical management and facilitate earlier intervention in affected relatives. Few studies have characterized differences in genetic testing by race/ethnicity.<h4>Methods</h4>We identified young adults ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2020, :]

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Young-onset colorectal cancer risk among individuals with iron-deficiency anaemia and haematochezia.

Joshua Demb, Lin Liu, Caitlin C Murphy, Chyke A Doubeni, María Elena Martínez, Samir Gupta,

<h4>Objective</h4>Young-onset colorectal cancer (YCRC) incidence is rising. Scant data exist on YCRC risk after presentation with concerning symptoms such as iron-deficiency anaemia (IDA) or haematochezia. We examined the association between IDA and YCRC, and haematochezia and YCRC.<h4>Design</h4>Cohort study of US Veterans aged 18-49 years receiving Veterans Health Administration (VHA) care ... Read more >>

Gut (Gut)
[2020, :]

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Increased care at discharge from COVID-19: The association between pre-admission frailty and increased care needs after hospital discharge; a multicentre European observational cohort study.

A Vilches-Moraga, A Price, P Braude, L Pearce, R Short, A Verduri, M Stechman, J T Collins, E Mitchell, A G Einarsson, S J Moug, T J Quinn, B Stubbs, K McCarthy, P K Myint, J Hewitt, B Carter, ,

<h4>Background</h4>The COVID-19 pandemic has placed significant pressure on health and social care. Survivors of COVID-19 may be left with substantial functional deficits requiring ongoing care. We aimed to determine whether pre-admission frailty was associated with increased care needs at discharge for patients admitted to hospital with COVID-19.<h4>Methods</h4>Patients were included if ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):408]

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Randomized, Controlled Comparison of Valveless Trocar (AirSeal®) versus Standard Insufflator with Ultralow Pneuomoperitoneum during Robotic Prostatectomy.

Ronney Abaza, Oscar E Martinez, Christopher Murphy,

<h4>Objective</h4>To compare valveless insufflation (Airseal®) with a conventional insufflation system (CIS) during robotic prostatectomy and the ability to use ultralow pneumoperitoneum at 6mmHg with each system as well as comparison of physiologic outcomes and pain scores.<h4>Methods</h4>We conducted a prospective study of 100 patients randomized to Airseal® or CIS during RP. ... Read more >>

J Endourol (Journal of endourology)
[2020, :]

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Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction.

David Shahnazaryan, Rana Khalil, Claire Wynne, Caroline A Jefferies, Joan Ní Gabhann-Dromgoole, Conor C Murphy,

Herpes simplex keratitis (HSK), caused by herpes simplex virus type 1 (HSV-1) infection, is the commonest cause of infectious blindness in the developed world. Following infection the virus is initially suspended in the tear film, where it encounters a multi-pronged immune response comprising enzymes, complement, immunoglobulins and crucially, a range ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):22216]

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Exercise Recovery Practices of Wheelchair Court Sports Athletes.

Conor J Murphy, Barry S Mason, Vicky L Goosey-Tolfrey,

<h4>Abstract</h4>Murphy, CJ, Mason, BS, and Goosey-Tolfrey, VL. Exercise recovery practices of wheelchair court sports athletes. J Strength Cond Res XX(X): 000-000, 2020-Research that describes the recovery practices of Para-athletes around training and competition is limited. This study investigated if and why athletes in wheelchair court sports (basketball, rugby, and tennis) ... Read more >>

J Strength Cond Res (Journal of strength and conditioning research)
[2020, Publish Ahead of Print:]

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Combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells.

Angelos Papadopoulos, Varvara Chalmantzi, Olga Mikhaylichenko, Marko Hyvönen, Dimitris Stellas, Aditi Kanhere, John Heath, Debbie L Cunningham, Theodore Fotsis, Carol Murphy,

Human embryonic stem cells (hESCs) are an invaluable tool in the fields of embryology and regenerative medicine. Activin A and BMP4 are well-characterised growth factors implicated in pluripotency and differentiation. In the current study, hESCs are cultured in a modified version of mTeSR1, where low concentrations of ActivinA substitute for ... Read more >>

Stem Cell Res (Stem cell research)
[2020, 50:102133]

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Problems faced by people living at home with dementia and incontinence: causes, consequences and potential solutions.

Catherine Murphy, Christine De Laine, Margaret Macaulay, Kelly Hislop Lennie, Mandy Fader,

<h4>Background</h4>many people living at home with dementia (PLWD) also have poorly managed toilet-use or incontinence problems with damaging consequences for both people with dementia, unpaid carers and healthcare professionals (HCPs). Currently, there are no theoretically or empirically based interventions to help. The underlying causes and subsequent consequences of these problems ... Read more >>

Age Ageing (Age and ageing)
[2020, :]

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Irish National Diabetic RetinaScreen Programme: report on five rounds of retinopathy screening and screen-positive referrals. (INDEAR study report no. 1).

Rajiv Pandey, Margaret M Morgan, Colette Murphy, Helen Kavanagh, Robert Acheson, Mark Cahill, Patricia McGettrick, Louise O'Toole, Fatima Hamroush, Therese Mooney, Helen Byrne, Patricia Fitzpatrick, David J Keegan,

<h4>Objective</h4>To study the uptake of annual diabetic retinopathy screening and study the 5-year trends in the detection of screen-positive diabetic retinopathy and non-diabetes-related eye disease in a cohort of annually screened individuals.<h4>Design</h4>Retrospective retinopathy screening attendance and retinopathy grading analysis.<h4>Setting</h4>Community-based retinopathy screening centres for the Diabetic RetinaScreen Programme.<h4>Participants</h4>171 557 were identified ... Read more >>

Br J Ophthalmol (The British journal of ophthalmology)
[2020, :]

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Randomized Clinical Trial of Inreach With or Without Mailed Outreach to Promote Hepatitis C Screening in a Difficult-to-Reach Patient Population.

Nirali Desai, Nicole E Rich, Mamta K Jain, James-Michael Blackwell, Caitlin C Murphy, Patrice Perryman, Jennifer McBryde, Lisa Quirk, Christopher Clark, Deyaun Villarreal, Akbar K Waljee, Purva Gopal, Amit G Singal,

<h4>Introduction</h4>Hepatitis C virus (HCV) treatment can significantly reduce the risk of liver-related mortality; however, many patients remain unaware of their infection in clinical practice. The aim of this study is to compare the effectiveness of inreach, with and without mailed outreach, to increase HCV screening and follow-up in a large, ... Read more >>

Am J Gastroenterol (The American journal of gastroenterology)
[2020, Publish Ahead of Print:]

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Multidimensional elements of impulsivity as shared and unique risk factors for food addiction and alcohol misuse.

Meenu Minhas, Cara M Murphy, Iris M Balodis, Samuel F Acuff, Joanna Buscemi, James G Murphy, James MacKillop,

Food addiction (FA) and alcohol misuse tend to co-occur, which suggests shared factors in the etiology and persistence of these health behaviors. One shared factor that has been linked to both is impulsivity, a multidimensional construct reflecting multiple facets of self-regulatory capacity. However, co-occurrence also raises issues of possible confounding ... Read more >>

Appetite (Appetite)
[2021, 159:105052]

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NIH Workshop Report: sensory nutrition and disease.

Danielle R Reed, Amber L Alhadeff, Gary K Beauchamp, Nirupa Chaudhari, Valerie B Duffy, Monica Dus, Alfredo Fontanini, John I Glendinning, Barry G Green, Paule V Joseph, George A Kyriazis, Mark Lyte, Padma Maruvada, John P McGann, John T McLaughlin, Timothy H Moran, Claire Murphy, Emily E Noble, M Yanina Pepino, Jennifer L Pluznick, Kristina I Rother, Enrique Saez, Alan C Spector, Catia Sternini, Richard D Mattes,

In November 2019, the NIH held the "Sensory Nutrition and Disease" workshop to challenge multidisciplinary researchers working at the interface of sensory science, food science, psychology, neuroscience, nutrition, and health sciences to explore how chemosensation influences dietary choice and health. This report summarizes deliberations of the workshop, as well as ... Read more >>

Am J Clin Nutr (The American journal of clinical nutrition)
[2020, :]

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