Full Text Journal Articles by
Author Bryan Baker

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Impact of Isolated Burns on Major Organs: A Large Animal Model Characterized.

David M Burmeister, Matthew K McIntyre, Bryan A Baker, Julie A Rizzo, Ammon Brown, Shanmugasundaram Natesan, Kevin K Chung, Robert J Christy,

Severe burn results in systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction (MOD). Currently, large-animal models of burn-induced SIRS/MOD mostly use secondary insults resulting in a paucity of knowledge on the effect of burn alone on different organ systems. The objective of the current study was to develop and ... Read more >>

Shock (Shock (Augusta, Ga.))
[2016, 46(3 Suppl 1):137-147]

Cited: 4 times

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Ontology analysis of global gene expression differences of human bone marrow stromal cells cultured on 3D scaffolds or 2D films.

Bryan A Baker, P Scott Pine, Kaushik Chatterjee, Girish Kumar, Nancy J Lin, Jennifer H McDaniel, Marc L Salit, Carl G Simon,

Differences in gene expression of human bone marrow stromal cells (hBMSCs) during culture in three-dimensional (3D) nanofiber scaffolds or on two-dimensional (2D) films were investigated via pathway analysis of microarray mRNA expression profiles. Previous work has shown that hBMSC culture in nanofiber scaffolds can induce osteogenic differentiation in the absence ... Read more >>

Biomaterials (Biomaterials)
[2014, 35(25):6716-6726]

Cited: 13 times

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Biopolymer/Calcium phosphate scaffolds for bone tissue engineering.

Jianhua Li, Bryan A Baker, Xiaoning Mou, Na Ren, Jichuan Qiu, Robert I Boughton, Hong Liu,

With nearly 30 years of progress, tissue engineering has shown promise in developing solutions for tissue repair and regeneration. Scaffolds, together with cells and growth factors, are key components of this development. Recently, an increasing number of studies have reported on the design and fabrication of scaffolding materials. In particular, ... Read more >>

Adv Healthc Mater (Advanced healthcare materials)
[2014, 3(4):469-484]

Cited: 26 times

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Twenty percent of a representative sample of patients taking bupropion have abnormal, asymptomatic electroencephalographic findings.

Matthew Macaluso, Rosey Zackula, Inna D'Empaire, Bryan Baker, Kore Liow, Sheldon H Preskorn,

The risk of dose-dependent seizures is a safety issue with bupropion hydrochloride. To evaluate the presence of specific electroencephalographic (EEG) waveforms, 210 adult subjects taking stable doses of bupropion hydrochloride were recruited to undergo 2 EEGs in a prospective, single-center cohort study. The occurrence of spike waves, sharp waves, and ... Read more >>

J Clin Psychopharmacol (Journal of clinical psychopharmacology)
[2010, 30(3):312-317]

Cited: 6 times

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An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder.

Sheldon H Preskorn, Bryan Baker, Sheela Kolluri, Frank S Menniti, Michael Krams, Jaren W Landen,

This randomized, placebo-controlled, double-blind study was the first to evaluate the antidepressant efficacy, safety, and tolerability of an NR2B subunit-selective N-methyl-D-aspartate receptor antagonist, CP-101,606. Subjects had major depression, according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and a history of treatment refractoriness to least 1 adequate ... Read more >>

J Clin Psychopharmacol (Journal of clinical psychopharmacology)
[2008, 28(6):631-637]

Cited: 279 times

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Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers.

Sheldon H Preskorn, David J Greenblatt, David Flockhart, Yan Luo, Elke S Perloff, Jerold S Harmatz, Bryan Baker, Alisa Klick-Davis, Zereusenay Desta, Tal Burt,

This study is the first to directly compare the relative effects of duloxetine, escitalopram, and sertraline on the functional activity of the drug-metabolizing cytochrome P450 2D6 enzyme as assessed by changes in the pharmacokinetics of the cytochrome P450 2D6 model substrate drug, metoprolol. Single-dose pharmacokinetics of metoprolol were measured before ... Read more >>

J Clin Psychopharmacol (Journal of clinical psychopharmacology)
[2007, 27(1):28-34]

Cited: 34 times

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Effect of study criteria on recruitment and generalizability of the results.

Ahsan Y Khan, Sheldon H Preskorn, Bryan Baker,

<h4>Objective</h4>Clinical trials are indispensable to drug approval process. This research examined the effect of a specific study criteria on recruitment and generalizability of the results.<h4>Methods</h4>The following were reviewed: (a) the usual inclusion and exclusion criteria for the antipsychotic trials performed at the Institute; (b) epidemiologic data, to determine the effect ... Read more >>

J Clin Psychopharmacol (Journal of clinical psychopharmacology)
[2005, 25(3):271-275]

Cited: 24 times

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The overlap of DSM-IV syndromes: potential implications for the practice of polypsychopharmacology, psychiatric drug development, and the human genome project.

Sheldon H Preskorn, Bryan Baker,

J Psychiatr Pract (Journal of psychiatric practice)
[2002, 8(3):170-177]

Cited: 14 times

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