Full Text Journal Articles by
Author Brian P Johnson

Advertisement

Find full text journal articles






Chronic Poststroke Deficits in Gross and Fine Motor Control of the Ipsilesional Upper Limb.

Brian P Johnson, Kelly P Westlake,

<h4>Objectives</h4>Individuals with stroke often experience contralesional and ipsilesional arm motor deficits. The aim of this study was to compare fine and gross motor hand dexterity of the ipsilesional hand post-stroke with controls, normative values, and the contralesional hand.<h4>Design</h4>Data were collected from right-handed individuals with chronic stroke (n = 20), age-/sex-matched ... Read more >>

Am J Phys Med Rehabil (American journal of physical medicine & rehabilitation)
[2021, 100(4):345-348]

Cited: 0 times

View full text PDF listing >>



Crowdsourcing in Cognitive and Systems Neuroscience.

Brian P Johnson, Eran Dayan, Nitzan Censor, Leonardo G Cohen,

Behavioral research in cognitive and human systems neuroscience has been largely carried out in-person in laboratory settings. Underpowering and lack of reproducibility due to small sample sizes have weakened conclusions of these investigations. In other disciplines, such as neuroeconomics and social sciences, crowdsourcing has been extensively utilized as a data ... Read more >>

Neuroscientist (The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry)
[2021, :10738584211017018]

Cited: 0 times

View full text PDF listing >>



Advertisement

The Intersection of Offline Learning and Rehabilitation.

Brian P Johnson, Leonardo G Cohen, Kelly P Westlake,

Front Hum Neurosci (Frontiers in human neuroscience)
[2021, 15:667574]

Cited: 0 times

View full text PDF listing >>



A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development.

Brian P Johnson, Ross A Vitek, Molly M Morgan, Dustin M Fink, Tyler G Beames, Peter G Geiger, David J Beebe, Robert J Lipinski,

Paracrine signaling in the tissue microenvironment is a central mediator of morphogenesis, and modeling this dynamic intercellular activity <i>in vitro</i> is critical to understanding normal and abnormal development. For example, Sonic Hedgehog (Shh) signaling is a conserved mechanism involved in multiple developmental processes and strongly linked to human birth defects ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2021, 9:621442]

Cited: 0 times

View full text PDF listing >>



Engineered Perineural Vascular Plexus for Modeling Developmental Toxicity.

Gaurav Kaushik, Kartik Gupta, Victoria Harms, Elizabeth Torr, Jonathan Evans, Hunter J Johnson, Cheryl Soref, Suehelay Acevedo-Acevedo, Jessica Antosiewicz-Bourget, Daniel Mamott, Peyton Uhl, Brian P Johnson, Sean P Palecek, David J Beebe, James A Thomson, William T Daly, William L Murphy,

There is a vital need to develop in vitro models of the developing human brain to recapitulate the biological effects that toxic compounds have on the brain. To model perineural vascular plexus (PNVP) in vitro, which is a key stage in embryonic development, human embryonic stem cells (hESC)-derived endothelial cells ... Read more >>

Adv Healthc Mater (Advanced healthcare materials)
[2020, 9(16):e2000825]

Cited: 2 times

View full text PDF listing >>



Sensorimotor performance is improved by targeted memory reactivation during a daytime nap in healthy older adults.

Brian P Johnson, Steven M Scharf, Avelino C Verceles, Kelly P Westlake,

Sensorimotor consolidation occurs during sleep. However, the benefit of sleep-based consolidation decreases with age due to decreased sleep quality and quantity. This study aimed to enhance sensorimotor performance through repetitive delivery of task-based auditory cues during sleep, known as targeted memory reactivation (TMR). Healthy older adults performed a non-dominant arm ... Read more >>

Neurosci Lett (Neuroscience letters)
[2020, 731:134973]

Cited: 1 time

View full text PDF listing >>



Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro.

Molly M Morgan, Linda A Schuler, Jordan C Ciciliano, Brian P Johnson, Elaine T Alarid, David J Beebe,

Accumulating evidence suggests that our ability to predict chemical effects on breast cancer is limited by a lack of physiologically relevant in vitro models; the typical in vitro breast cancer model consists of the cancer cell and excludes the mammary microenvironment. As the effects of the microenvironment on cancer cell ... Read more >>

Integr Biol (Camb) (Integrative biology : quantitative biosciences from nano to macro)
[2020, 12(2):21-33]

Cited: 2 times

View full text PDF listing >>



Systematic Review Investigating the Effects of Nonpharmacological Interventions During Sleep to Enhance Physical Rehabilitation Outcomes in People With Neurological Diagnoses.

Brian P Johnson, Andrea G Shipper, Kelly P Westlake,

<h4>Objective</h4>Conduct a systematic review of nonpharmacological interventions applied during sleep to enhance physical rehabilitation outcomes of individuals with a neurological diagnosis.<h4>Data sources</h4>Three online databases were searched for original research.<h4>Study selection</h4>Intervention studies were included that used outcome measures of impairment, activity, and/or participation.<h4>Data extraction</h4>Two reviewers independently screened 2287 titles and abstracts, ... Read more >>

Neurorehabil Neural Repair (Neurorehabilitation and neural repair)
[2019, 33(5):345-354]

Cited: 1 time

View full text PDF listing >>



Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model.

Molly M Morgan, Lisa M Arendt, Elaine T Alarid, David J Beebe, Brian P Johnson,

Aromatase inhibitors are the preferred treatment for certain women with estrogen receptor (ER)-positive breast cancer, but evidence suggests that women with obesity experience aromatase inhibitor resistance at higher rates. To compare how stromal cells derived from women who are lean or obese influence response to the aromatase inhibitor (anastrazole), we ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2019, 33(7):8623-8633]

Cited: 8 times

View full text PDF listing >>



Use of targeted memory reactivation enhances skill performance during a nap and enhances declarative memory during wake in healthy young adults.

Brian P Johnson, Steven M Scharf, Avelino C Verceles, Kelly P Westlake,

Sleep is an important component of motor memory consolidation and learning, providing a critical tool to enhance training and rehabilitation. Following initial skill acquisition, memory consolidation is largely a result of non-rapid eye movement sleep over either a full night or a nap. Targeted memory reactivation is one method used ... Read more >>

J Sleep Res (Journal of sleep research)
[2019, 28(5):e12832]

Cited: 2 times

View full text PDF listing >>



Evaluation of PEG-based hydrogel influence on estrogen receptor driven responses in MCF7 breast cancer cells.

Megan K Livingston, Molly M Morgan, William T Daly, William L Murphy, Brian P Johnson, David J Beebe, Maria Virumbrales-Muñoz,

Extracellular matrix (ECM) mimicking hydrogel scaffolds have greatly improved the physiological relevance of <i>in vitro</i> assays, but introduce another dimension that creates variability in cell related readouts when compared to traditional 2D cells-on-plastic assays. We have developed a synthetic poly(ethylene glycol) (PEG) based ECM mimicking hydrogel and tested it against ... Read more >>

ACS Biomater Sci Eng (ACS biomaterials science & engineering)
[2019, 5(11):6089-6098]

Cited: 2 times

View full text PDF listing >>



Mammary fibroblasts reduce apoptosis and speed estrogen-induced hyperplasia in an organotypic MCF7-derived duct model.

Molly M Morgan, Megan K Livingston, Jay W Warrick, Eli M Stanek, Elaine T Alarid, David J Beebe, Brian P Johnson,

The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We exposed an organotypic mammary model ... Read more >>

Sci Rep (Scientific reports)
[2018, 8(1):7139]

Cited: 19 times

View full text PDF listing >>



New Look, and More Often.

Brian P Johnson Johnson,

Chem Rec (Chemical record (New York, N.Y.))
[2018, 18(1):2-3]

Cited: 0 times

View full text PDF listing >>



Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment.

Brian P Johnson, Ross A Vitek, Peter G Geiger, Wei Huang, David F Jarrard, Joshua M Lang, David J Beebe,

Cellular heterogeneity within the tissue microenvironment may underlie chemotherapeutic resistance and response, enabling tumor evolution; however, this heterogeneity it is difficult to characterize. Here, we present a new approach-pathology-guided micropunching (PGM)-that enables identification and characterization of heterogeneous foci identified in viable human and animal model tissue slices. This technique consists ... Read more >>

Biotechniques (BioTechniques)
[2018, 64(1):13-19]

Cited: 1 time

View full text PDF listing >>



Further examination of embedded performance validity indicators for the Conners' Continuous Performance Test and Brief Test of Attention in a large outpatient clinical sample.

Michael J Sharland, Stephen C Waring, Brian P Johnson, Allise M Taran, Travis A Rusin, Andrew M Pattock, Jeanette A Palcher,

<h4>Objective</h4>Assessing test performance validity is a standard clinical practice and although studies have examined the utility of cognitive/memory measures, few have examined attention measures as indicators of performance validity beyond the Reliable Digit Span. The current study further investigates the classification probability of embedded Performance Validity Tests (PVTs) within the ... Read more >>

Clin Neuropsychol (The Clinical neuropsychologist)
[2018, 32(1):98-108]

Cited: 2 times

View full text PDF listing >>



Targeted Memory Reactivation During Sleep, But Not Wake, Enhances Sensorimotor Skill Performance: A Pilot Study.

Brian P Johnson, Steven M Scharf, Kelly P Westlake,

The benefits of sleep on memory consolidation have been enhanced for declarative and motor sequence learning through replaying classically conditioned auditory stimuli during sleep, known as targeted memory reactivation (TMR). However, it is unknown if TMR can influence performance of a sensorimotor skill, in the absence of the cognitive requirements ... Read more >>

J Mot Behav (Journal of motor behavior)
[2018, 50(2):202-209]

Cited: 2 times

View full text PDF listing >>



Link Between Parkinson Disease and Rapid Eye Movement Sleep Behavior Disorder With Dream Enactment: Possible Implications for Early Rehabilitation.

Brian P Johnson, Kelly P Westlake,

The purpose of this article is 2-fold: first, to inform readers of the link between the loss of motor inhibition during rapid eye movement (REM) sleep dreaming, diagnosed as REM sleep behavior disorder, and the future onset of neurodegenerative disorders, such as Parkinson disease and dementia with Lewy bodies; it ... Read more >>

Arch Phys Med Rehabil (Archives of physical medicine and rehabilitation)
[2018, 99(2):411-415]

Cited: 4 times

View full text PDF listing >>



Well-Covered.

Brian P Johnson,

Chem Rec (Chemical record (New York, N.Y.))
[2017, 17(1):2-3]

Cited: 0 times

View full text PDF listing >>



The Nozoe Autograph Books Project: An Assessment.

Jeffrey I Seeman, Brian P Johnson,

Bonding beyond Borders is a fitting title to the Nozoe Autograph Books project, as the books and their publication involved innumerable contributors from around the globe all in the spirit of personal collaboration. The editors of this project share details of how the project came into being and give their ... Read more >>

Chem Rec (Chemical record (New York, N.Y.))
[2015, 15(6):1165-1174]

Cited: 1 time

View full text PDF listing >>



cyclo-P4 Building Blocks: Achieving Non-Classical Fullerene Topology and Beyond.

Fabian Dielmann, Eugenia V Peresypkina, Barbara Krämer, Florian Hastreiter, Brian P Johnson, Manfred Zabel, Claudia Heindl, Manfred Scheer,

The cyclo-P<sub>4</sub> complexes [Cp<sup>R</sup> Ta(CO)<sub>2</sub> (η<sup>4</sup> -P<sub>4</sub> )] (Cp<sup>R</sup> : Cp''=1,3-C<sub>5</sub> H<sub>3</sub> tBu<sub>2</sub> , Cp'''=1,2,4-C<sub>5</sub> H<sub>2</sub> tBu<sub>3</sub> ) turned out to be predestined for the formation of hollow spherical supramolecules with non-classical fullerene-like topology. The resulting assemblies constructed with CuX (X=Cl, Br) showed a highly symmetric 32-vertex core of solely ... Read more >>

Angew Chem Int Ed Engl (Angewandte Chemie (International ed. in English))
[2016, 55(47):14833-14837]

Cited: 5 times

View full text PDF listing >>



Personalized in vitro cancer models to predict therapeutic response: Challenges and a framework for improvement.

Molly M Morgan, Brian P Johnson, Megan K Livingston, Linda A Schuler, Elaine T Alarid, Kyung E Sung, David J Beebe,

Personalized cancer therapy focuses on characterizing the relevant phenotypes of the patient, as well as the patient's tumor, to predict the most effective cancer therapy. Historically, these methods have not proven predictive in regards to predicting therapeutic response. Emerging culture platforms are designed to better recapitulate the in vivo environment, ... Read more >>

Pharmacol Ther (Pharmacology & therapeutics)
[2016, 165:79-92]

Cited: 24 times

View full text PDF listing >>



Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virus.

William D Arndt, Stacy D White, Brian P Johnson, Trung Huynh, Jeffrey Liao, Heather Harrington, Samantha Cotsmire, Karen V Kibler, Jeffrey Langland, Bertram L Jacobs,

Monkeypox virus (MPXV) infection fails to activate the host anti-viral protein, PKR, despite lacking a full-length homologue of the vaccinia virus (VACV) PKR inhibitor, E3. Since PKR can be activated by dsRNA produced during a viral infection, we have analyzed the accumulation of dsRNA in MPXV-infected cells. MPXV infection led ... Read more >>

Virology (Virology)
[2016, 497:125-135]

Cited: 9 times

View full text PDF listing >>



Variation and Trends in Lower Extremity Amputation Rates in Los Angeles County Hospitals 2000-2010.

Ayad Jindeel, Charles Gessert, Brian P Johnson,

Lower extremity amputation (LEA) is a preventable complication of diabetes and peripheral vascular disease. Hospital-related factors associated with higher LEA are low hospital LEA revascularization volume, rural setting, and nonteaching status. In this study, we describe LEA rates in health care systems and hospitals in Los Angeles County from 2000 ... Read more >>

Int J Low Extrem Wounds (The international journal of lower extremity wounds)
[2016, 15(3):232-240]

Cited: 3 times

View full text PDF listing >>



Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression.

Xiao-Min Yu, Renata Jaskula-Sztul, Maria R Georgen, Zviadi Aburjania, Yash R Somnay, Glen Leverson, Rebecca S Sippel, Ricardo V Lloyd, Brian P Johnson, Herbert Chen,

<h4>Purpose</h4>Notch1, a transmembrane receptor, has been recently shown to aid in the determination of thyroid cell fate associated with tumorigenesis. This study aimed to investigate the clinical relevance of Notch1 and its role in the regulation of differentiated thyroid cancer (DTC) behavior.<h4>Experimental design</h4>We examined Notch1 expression level and its relationship ... Read more >>

Clin Cancer Res (Clinical cancer research : an official journal of the American Association for Cancer Research)
[2016, 22(14):3582-3592]

Cited: 17 times

View full text PDF listing >>



Up Close and Personal.

Brian P Johnson,

Chem Rec (Chemical record (New York, N.Y.))
[2016, 16(1):2-3]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.0616 s