Full Text Journal Articles by
Author Brent Egan

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Sociodemographic Determinants of Life's Simple 7: Implications for Achieving Cardiovascular Health and Health Equity Goals.

Brent M Egan, Jiexiang Li, Susan E Sutherland, Daniel W Jones, Keith C Ferdinand, Yuling Hong, Eduardo Sanchez,

Background:Life's Simple 7 (LS7; nutrition, physical activity, cigarette use, body mass index, blood pressure, cholesterol, glucose) predicts cardiovascular health. The principal objective of our study was to define demographic and socioeconomic factors associated with LS7 to better inform programs addressing cardiovascular health and health equity. Methods:National Health and Nutrition Examination ... Read more >>

Ethn Dis (Ethnicity & disease)
[2020, 30(4):637-650]

Cited: 0 times

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Antihypertensive Treatment in Elderly Frail Patients: Evidence From a Large Italian Database.

Brent M Egan, Susan E Sutherland,

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2020, 76(2):330-332]

Cited: 0 times

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Hypertension in military veterans is associated with combat exposure and combat injury.

Brent M Egan,

J. Hypertens. (Journal of hypertension)
[2020, 38(7):1255-1256]

Cited: 0 times

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Nicotine replacement therapy sampling for smoking cessation within primary care: results from a pragmatic cluster randomized clinical trial.

Matthew J Carpenter, Amy E Wahlquist, Jennifer Dahne, Kevin M Gray, Elizabeth Garrett-Mayer, K Michael Cummings, Robert Davis, Brent M Egan,

BACKGROUND AND AIMS:Within the context of busy clinical settings, health-care providers need practical, evidence-based options to engage smokers in quitting. Sampling of nicotine replacement therapy [i.e. provision of nicotine replacement therapy (NRT starter kits)] is a brief, pragmatic strategy to address this need. We aimed to compare the effects of ... Read more >>

Addiction (Addiction (Abingdon, England))
[2020, 115(7):1358-1367]

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The prevalence of concurrently raised blood glucose and blood pressure in India.

Brent M Egan,

J Hypertens (Journal of hypertension)
[2019, 37(9):1788-1789]

Cited: 0 times

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A cluster-based approach for integrating clinical management of Medicare beneficiaries with multiple chronic conditions.

Brent M Egan, Susan E Sutherland, Peter L Tilkemeier, Robert A Davis, Valinda Rutledge, Angelo Sinopoli,

BACKGROUND:Approximately 28% of adults have ≥3 chronic conditions (CCs), accounting for two-thirds of U.S. healthcare costs, and often having suboptimal outcomes. Despite Institute of Medicine recommendations in 2001 to integrate guidelines for multiple CCs, progress is minimal. The vast number of unique combinations of CCs may limit progress. METHODS AND ... Read more >>

PLoS ONE (PloS one)
[2019, 14(6):e0217696]

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Optimal Systolic Blood Pressure Target in Resistant Hypertension.

Brent M Egan,

Am. J. Med. (The American journal of medicine)
[2019, 132(7):e623]

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The global burden of hypertension exceeds 1.4 billion people: should a systolic blood pressure target below 130 become the universal standard?

Brent M Egan, Sverre E Kjeldsen, Guido Grassi, Murray Esler, Guiseppe Mancia,

: In 2010, 1.4 billion people globally had hypertension, with 14% controlled to systolic blood pressure (SBP, mmHg) below 140, which contributes to 18 million cardiovascular deaths annually. Recent hypertension guidelines endorsed SBP targets below 130 or lower for all or some hypertensive patients to reduce cardiovascular events (CVEs) more ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, 37(6):1148-1153]

Cited: 6 times

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Hypertensive heart disease: Benefit of carvedilol in hemodynamic, left ventricular remodeling, and survival.

Renata F Dominguez, Valeria A da Costa-Hong, Luan Ferretti, Fabio Fernandes, Luiz A Bortolotto, Fernanda M Consolim-Colombo, Brent M Egan, Heno F Lopes,

Objectives:The aim of this study was to determine if carvedilol improved structural and functional changes in the left ventricle and reduced mortality in patients with hypertensive heart disease. Methods:Blood pressure, heart rate, echocardiographic parameters, and laboratory variables, were assessed pre and post treatment with carvedilol in 98 eligible patients. Results:Carvedilol ... Read more >>

(SAGE open medicine)
[2019, 7:2050312118823582]

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Adherence in Hypertension.

Michel Burnier, Brent M Egan,

The global epidemic of hypertension is largely uncontrolled and hypertension remains the leading cause of noncommunicable disease deaths worldwide. Suboptimal adherence, which includes failure to initiate pharmacotherapy, to take medications as often as prescribed, and to persist on therapy long-term, is a well-recognized factor contributing to the poor control of ... Read more >>

Circ. Res. (Circulation research)
[2019, 124(7):1124-1140]

Cited: 9 times

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Implementation of the 2017 American College of Cardiology/American Heart Association Hypertension Guideline.

Brent M Egan,

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2019, 73(2):288-290]

Cited: 1 time

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Prognostic value of blood pressure control delay in newly diagnosed hypertensive patients.

Brent M Egan,

J. Hypertens. (Journal of hypertension)
[2019, 37(2):290-291]

Cited: 0 times

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Improving Hypertension Control in Primary Care With the Measure Accurately, Act Rapidly, and Partner With Patients Protocol.

Brent M Egan, Susan E Sutherland, Michael Rakotz, Jianing Yang, R Bruce Hanlin, Robert A Davis, Gregory Wozniak,

Better blood pressure (BP; mm Hg) control is a pivotal national strategy for preventing cardiovascular events. Measure accurately, Act rapidly, and Partner with patients (MAP) with practice facilitation improved BP control (<140/<90 mm Hg) from 61.2% to 89.8% during a 6-month pilot study in one primary care clinic. Current study objectives included ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2018, 72(6):1320-1327]

Cited: 2 times

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Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.

Robert M Carey, David A Calhoun, George L Bakris, Robert D Brook, Stacie L Daugherty, Cheryl R Dennison-Himmelfarb, Brent M Egan, John M Flack, Samuel S Gidding, Eric Judd, Daniel T Lackland, Cheryl L Laffer, Christopher Newton-Cheh, Steven M Smith, Sandra J Taler, Stephen C Textor, Tanya N Turan, William B White, ,

Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a long-acting calcium channel blocker, a blocker of the renin-angiotensin system (angiotensin-converting enzyme inhibitor or angiotensin receptor blocker), and a diuretic. The antihypertensive drugs should ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2018, 72(5):e53-e90]

Cited: 32 times

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Cost-Utility of an Objective Biochemical Measure to Improve Adherence to Antihypertensive Treatment.

Brent M Egan, Caroline Rudisill,

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2018, 72(5):1090-1092]

Cited: 0 times

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Insights on β-blockers for the treatment of hypertension: A survey of health care practitioners.

Brent Egan, John Flack, Mehul Patel, Sofia Lombera,

A quantitative survey was completed by 103 primary care physicians (PCPs) and 59 cardiologists who regularly prescribed β-blockers to assess knowledge and use of this heterogeneous drug class for hypertension. More cardiologists than PCPs chose β-blockers as initial antihypertensive therapy (30% vs 17%, P < 0.01). Metoprolol and carvedilol were the most ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2018, 20(10):1464-1472]

Cited: 1 time

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Risk of Hospitalization for Cardiovascular Events with β-Blockers in Hypertensive Patients: A Retrospective Cohort Study.

Jan Basile, Brent Egan, Henry Punzi, Sanjida Ali, Qian Li, Mehul Patel, Joel Neutel,

INTRODUCTION:β-Blockers are a heterogenous class of drugs that are no longer recommended for initial antihypertension monotherapy due to unfavorable long-term cardiovascular events observed with non-vasodilatory β-blockers. However, the comparative cardiovascular event risk between the vasodilatory β1-selective antagonist/β3 agonist nebivolol and non-vasodilatory β1-blockers, atenolol and metoprolol, is unknown. METHODS:Incident nebivolol, atenolol, ... Read more >>

(Cardiology and therapy)
[2018, 7(2):173-183]

Cited: 1 time

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Nicotine replacement therapy sampling via primary care: Methods from a pragmatic cluster randomized clinical trial.

Jennifer Dahne, Amy E Wahlquist, Amy S Boatright, Elizabeth Garrett-Mayer, Douglas O Fleming, Robert Davis, Brent Egan, Matthew J Carpenter,

BACKGROUND:Primary care is the most important point of healthcare contact for smokers. Brief physician advice to quit, based on the 5As/AAR model, offers some efficacy but is inconsistently administered and has limited population impact. Nicotine replacement therapy (NRT) sampling, defined as provision of a brief NRT starter kit, when added ... Read more >>

Contemp Clin Trials (Contemporary clinical trials)
[2018, 72:1-7]

Cited: 1 time

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Defining Hypertension by Blood Pressure 130/80 mm Hg Leads to an Impressive Burden of Hypertension in Young and Middle-Aged Black Adults: Follow-Up in the CARDIA Study.

Brent M Egan,

J Am Heart Assoc (Journal of the American Heart Association)
[2018, 7(14):]

Cited: 0 times

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Differences in primary cardiovascular disease prevention between the 2013 and 2016 cholesterol guidelines and impact of the 2017 hypertension guideline in the United States.

Brent M Egan, Jiexiang Li, Robert A Davis, Kevin A Fiscella, Jonathan N Tobin, Daniel W Jones, Angelo Sinopoli,

The US Preventive Services Task Force cholesterol guideline recommended statins for fewer adults than the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline by setting a higher 10-year atherosclerotic cardiovascular disease threshold (≥10.0% vs ≥7.5%) and requiring concomitant diabetes mellitus, hypertension, dyslipidemia, or cigarette smoking. The 2017 ACC/AHA hypertension ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2018, 20(6):991-1000]

Cited: 0 times

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Measure Accurately, Act Rapidly, and Partner With Patients (MAP) improves hypertension control in medically underserved patients: Care Coordination Institute and American Medical Association Hypertension Control Project Pilot Study results.

Robert B Hanlin, Irfan M Asif, Gregory Wozniak, Susan E Sutherland, Bijal Shah, Jianing Yang, Robert A Davis, Sean T Bryan, Michael Rakotz, Brent M Egan,

Measure Accurately, Act Rapidly, and Partner With Patients (MAP) is an evidence-based protocol implemented to improve hypertension control in a clinic for underserved patients (49.9% Medicaid and 50.2% black). Patients with hypertension seen during the year before intervention and with at least one visit during the 6-month intervention (N = 714) were ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2018, 20(1):79-87]

Cited: 6 times

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Cholesterol Control Among Uninsured Adults Did Not Improve From 2001-2004 to 2009-2012 as Disparities With Both Publicly and Privately Insured Adults Doubled.

Brent M Egan, Jiexiang Li, Sara M Sarasua, Robert A Davis, Kevin A Fiscella, Jonathan N Tobin, Daniel W Jones, Angelo Sinopoli,

BACKGROUND:Low-density lipoprotein cholesterol (LDL-C) control is higher among insured than uninsured adults, but data on time trends and contributing factors are incomplete and important for improving health equity. METHODS AND RESULTS:Awareness, treatment, and control of elevated LDL-C were compared among insured versus uninsured and publicly versus privately insured adults, aged ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2017, 6(11):]

Cited: 2 times

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Trends in Prehypertension and Hypertension Risk Factors in US Adults: 1999-2012.

John N Booth, Jiexiang Li, Lu Zhang, Liwei Chen, Paul Muntner, Brent Egan,

Prehypertension is associated with increased risk for hypertension and cardiovascular disease. Data are limited on the temporal changes in the prevalence of prehypertension and risk factors for hypertension and cardiovascular disease among US adults with prehypertension. We analyzed data from 30 958 US adults ≥20 years of age who participated ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2017, 70(2):275-284]

Cited: 23 times

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Opportunities for improving cardiovascular health outcomes in adults younger than 65 years with guideline-recommended statin therapy.

Sara M Sarasua, Jiexiang Li, German T Hernandez, Keith C Ferdinand, Jonathan N Tobin, Kevin A Fiscella, Daniel W Jones, Angelo Sinopoli, Brent M Egan,

The impact of age, race/ethnicity, healthcare insurance, and selected clinical variables on statin-preventable ASCVD were quantified in adults aged 21 to 79 years from National Health and Nutrition Examination Surveys 2007-2012 using the 2013 American College of Cardiology/American Heart Association guideline on the treatment of cholesterol. Among ≈42.4 million statin-eligible, untreated ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2017, 19(9):850-860]

Cited: 0 times

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Relationship between risk factor control and vascular events in the SAMMPRIS trial.

Tanya N Turan, Azhar Nizam, Michael J Lynn, Brent M Egan, Ngoc-Anh Le, Maria F Lopes-Virella, Kathie L Hermayer, Jamie Harrell, Colin P Derdeyn, David Fiorella, L Scott Janis, Bethany Lane, Jean Montgomery, Marc I Chimowitz,

OBJECTIVE:The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) study is the first stroke prevention trial to include protocol-driven intensive management of multiple risk factors. In this prespecified analysis, we aimed to investigate the relationship between risk factor control during follow-up and outcome of patients ... Read more >>

Neurology (Neurology)
[2017, 88(4):379-385]

Cited: 13 times

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