Full Text Journal Articles by
Author Brendan Major


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Diffusion Imaging Reveals Sex Differences in the White Matter Following Sports-Related Concussion.

David K Wright, Georgia F Symons, William T O'Brien, Stuart J McDonald, Akram Zamani, Brendan Major, Zhibin Chen, Daniel Costello, Rhys D Brady, Mujun Sun, Meng Law, Terence J O'Brien, Richelle Mychasiuk, Sandy R Shultz,

Sports-related concussion (SRC) is a serious health concern. However, the temporal profile of neuropathophysiological changes after SRC and how these relate to biological sex are still poorly understood. This preliminary study investigated whether diffusion-weighted magnetic resonance imaging (dMRI) was sensitive to neuropathophysiological changes following SRC; whether these changes were sex-specific; ... Read more >>

Cereb Cortex (Cerebral cortex (New York, N.Y. : 1991))
[2021, 31(10):4411-4419]

Cited: 0 times

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Visible Signs of Concussion and Cognitive Screening in Community Sports.

Jonathan Reyes, Biswadev Mitra, Michael Makdissi, Patrick Clifton, Jack V K Nguyen, Peter Harcourt, Teresa S Howard, Peter A Cameron, Jeffrey V Rosenfeld, Brendan P Major, Catherine Willmott,

Video surveillance and detection of players with visible signs of concussion by experienced medical staff facilitates rapid on-field screening of suspected concussion in professional sports. This method, however has not been validated in community sports where video footage is unavailable. This study aimed to explore the utility of visible signs ... Read more >>

J Neurotrauma (Journal of neurotrauma)
[2021, :]

Cited: 0 times

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Targeting the Cerebrovascular System: Next-Generation Biomarkers and Treatment for Mild Traumatic Brain Injury.

Tamara L Baker, Denes V Agoston, Rhys D Brady, Brendan Major, Stuart J McDonald, Richelle Mychasiuk, David K Wright, Glenn R Yamakawa, Mujun Sun, Sandy R Shultz,

The diagnosis, prognosis, and treatment of mild traumatic brain injuries (mTBIs), such as concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI adversely affect the cerebral vasculature, making cerebrovascular injury (CVI) a pathophysiological hallmark of mTBI. Given the importance of a healthy cerebrovascular system in overall ... Read more >>

Neuroscientist (The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry)
[2021, :10738584211012264]

Cited: 0 times

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Cerebral Cortical Activity Following Non-invasive Cerebellar Stimulation-a Systematic Review of Combined TMS and EEG Studies.

Lara Fernandez, Nigel C Rogasch, Michael Do, Gillian Clark, Brendan P Major, Wei-Peng Teo, Linda K Byrne, Peter G Enticott,

The cerebellum sends dense projections to both motor and non-motor regions of the cerebral cortex via the cerebellarthalamocortical tract. The integrity of this tract is crucial for healthy motor and cognitive function. This systematic review examines research using transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) to the ... Read more >>

Cerebellum (Cerebellum (London, England))
[2020, 19(2):309-335]

Cited: 4 times

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Concussion incidence and time-loss in Australian football: A systematic review.

Claire McNeel, Gillian M Clark, Charlotte B Davies, Brendan P Major, Jarrad A G Lum,

OBJECTIVES:Australian football is associated with a risk of concussion. However, despite the extensive and varied nature of literature devoted to this issue, concussion incidence has not been systematically evaluated. To address this, we aimed to conduct a meta-analysis of concussion incidence in Australian football. DESIGN:Systematic review. Prospero registration number: CRD42017064290. ... Read more >>

J Sci Med Sport (Journal of science and medicine in sport)
[2020, 23(2):125-133]

Cited: 1 time

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Learning to Expect: Predicting Sounds During Movement Is Related to Sensorimotor Association During Listening.

Jed D Burgess, Brendan P Major, Claire McNeel, Gillian M Clark, Jarrad A G Lum, Peter G Enticott,

Sensory experiences, such as sound, often result from our motor actions. Over time, repeated sound-producing performance can generate sensorimotor associations. However, it is not clear how sensory and motor information are associated. Here, we explore if sensory prediction is associated with the formation of sensorimotor associations during a learning task. ... Read more >>

Front Hum Neurosci (Frontiers in human neuroscience)
[2019, 13:215]

Cited: 0 times

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Effects of eccentric versus concentric contractions of the biceps brachii on intracortical inhibition and facilitation.

Christopher Latella, Alicia M Goodwill, Makii Muthalib, Ashlee M Hendy, Brendan Major, Kazunori Nosaka, Wei-Peng Teo,

Differences in the neural mechanisms underpinning eccentric (ECC) and concentric (CON) contractions exist; however, the acute effects of fatiguing muscle contractions on intracortical and corticospinal excitability are not well understood. Therefore, we compared maximal ECC and CON contractions of the right biceps brachii (BB) muscle for changes in corticospinal excitability, ... Read more >>

Scand J Med Sci Sports (Scandinavian journal of medicine & science in sports)
[2019, 29(3):369-379]

Cited: 2 times

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The Impact of Stimulation Intensity and Coil Type on Reliability and Tolerability of Cerebellar Brain Inhibition (CBI) via Dual-Coil TMS.

Lara Fernandez, Brendan P Major, Wei-Peng Teo, Linda K Byrne, Peter G Enticott,

Cerebellar brain inhibition (CBI) describes the inhibitory tone the cerebellum exerts on the primary motor cortex (M1). CBI can be indexed via a dual-coil transcranial magnetic stimulation protocol, whereby a conditioning stimulus (CS) is delivered to the cerebellum in advance of a test stimulus (TS) to M1. The CS is ... Read more >>

Cerebellum (Cerebellum (London, England))
[2018, 17(5):540-549]

Cited: 8 times

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Assessing cerebellar brain inhibition (CBI) via transcranial magnetic stimulation (TMS): A systematic review.

Lara Fernandez, Brendan P Major, Wei-Peng Teo, Linda K Byrne, Peter G Enticott,

The inhibitory tone that the cerebellum exerts on the primary motor cortex (M1) is known as cerebellar brain inhibition (CBI). Studies show CBI to be relevant to several motor functions, including adaptive motor learning and muscle control. CBI can be assessed noninvasively via transcranial magnetic stimulation (TMS) using a double-coil ... Read more >>

Neurosci Biobehav Rev (Neuroscience and biobehavioral reviews)
[2018, 86:176-206]

Cited: 19 times

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Effects of acute resistance training modality on corticospinal excitability, intra-cortical and neuromuscular responses.

Christopher Latella, Wei-Peng Teo, Dale Harris, Brendan Major, Dan VanderWesthuizen, Ashlee M Hendy,

<h4>Objective</h4>Although neural adaptations from strength training are known to occur, the acute responses associated with heavy-strength (HST) and hypertrophy training (HYT) remain unclear. Therefore, we aimed to compare the acute behaviour of corticospinal responses following a single session of HST vs HYT over a 72-h period.<h4>Methods</h4>Fourteen participants completed a random ... Read more >>

Eur J Appl Physiol (European journal of applied physiology)
[2017, 117(11):2211-2224]

Cited: 5 times

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Efficacy of neurostimulation to treat symptoms of Mal de Debarquement Syndrome. A preliminary study using repetitive transcranial magnetic stimulation.

Alan J Pearce, Charlotte P Davies, Brendan P Major,

Mal de debarquement syndrome (MdDS) is a rare and poorly understood condition of perceived continual motion. Using a multiple-case design (n = 13; 8 f; 63.5 ± 12.6 years), this study investigated the efficacy of eight 20-min sessions, over 4 weeks, of repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral pre-frontal cortex. Compared to sham, rTMS ... Read more >>

J Neuropsychol (Journal of neuropsychology)
[2015, 9(2):336-341]

Cited: 4 times

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Using transcranial magnetic stimulation to quantify electrophysiological changes following concussive brain injury: a systematic review.

Brendan P Major, Mark A Rogers, Alan J Pearce,

Mild traumatic brain injury (mTBI) and sports concussion are a growing public health concern, with increasing demands for more rigorous methods to quantify changes in the brain post-injury. Electrophysiology, and in particular, transcranial magnetic stimulation (TMS), have been demonstrated to provide prognostic value in a range of neurological conditions; however, ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2015, 42(4):394-405]

Cited: 16 times

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Faster VO(2) kinetics after eccentric contractions is explained by better matching of O(2) delivery to O(2) utilization.

Joshua P Nederveen, Brendan Major, Donald H Paterson, Juan M Murias,

<h4>Purpose</h4>This study examined the impact of eccentric exercise-induced muscle damage on the rate of adjustment in muscle deoxygenation and pulmonary O2 uptake (VO(2p)) kinetics during moderate exercise.<h4>Methods</h4>Fourteen males (25 ± 3 year; mean ± SD) completed three step transitions to 90 % θL before (Pre), 24 h (Post24) and 48 ... Read more >>

Eur J Appl Physiol (European journal of applied physiology)
[2014, 114(10):2169-2181]

Cited: 2 times

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Skeletal muscle morphology and contractile function in relation to muscle denervation in diabetic neuropathy.

Matti D Allen, Brendan Major, Kurt Kimpinski, Timothy J Doherty, Charles L Rice,

The objective of the study was to assess the effects of diabetic polyneuropathy (DPN) on muscle contractile properties in humans, and how these changes are related to alterations in muscle morphology and denervation. Patients with DPN (n = 12) were compared with age- and sex-matched controls (n = 12). Evoked ... Read more >>

J Appl Physiol (1985) (Journal of applied physiology (Bethesda, Md. : 1985))
[2014, 116(5):545-552]

Cited: 24 times

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