Full Text Journal Articles by
Author Biljana Stankovic

Advertisement

Find full text journal articles






Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection

Kristel Klaassen, Biljana Stankovic, Branka Zukic, Nikola Kotur, Vladimir Gasic, Sonja Pavlovic, Maja Stojiljkovic,

Abstract New coronavirus SARS-CoV-2 is capable to infect humans and cause a novel disease COVID-19. Aiming to understand a host genetic component of COVID-19, we focused on variants in genes encoding proteases and genes involved in innate immunity that could be important for susceptibility and resistance to SARS-CoV-2 infection. Analysis ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Pharmacogenomic Markers of Methotrexate Response in the Consolidation Phase of Pediatric Acute Lymphoblastic Leukemia Treatment.

Nikola Kotur, Jelena Lazic, Bojan Ristivojevic, Biljana Stankovic, Vladimir Gasic, Lidija Dokmanovic, Nada Krstovski, Goran Milosevic, Dragana Janic, Branka Zukic, Sonja Pavlovic,

Methotrexate (MTX) is one of the staples of pediatric acute lymphoblastic leukemia (ALL) treatment. MTX targets the folate metabolic pathway (FMP). Abnormal function of the enzymes in FMP, due to genetic aberrations, leads to adverse drug reactions. The aim of this study was to investigate variants in pharmacogenes involved in ... Read more >>

Genes (Basel) (Genes)
[2020, 11(4):]

Cited: 0 times

View full text PDF listing >>



Advertisement

Clinical Application of Thiopurine Pharmacogenomics in Pediatrics.

Sonja Pavlovic, Nikola Kotur, Biljana Stankovic, Vladimir Gasic, Marianna Lucafo, Giuliana Decorti, Branka Zukic,

BACKGROUND:Thiopurine drugs are used for the treatment of pediatric diseases. Inter-individual differences in the metabolism of these drugs greatly influence the risk of thiopurine induced toxicity and therapy failure. These differences are the consequence of genomic, epigenomic and transcriptomic variability among patients. Pharmacogenomics aims to individualize therapy according to the ... Read more >>

Curr. Drug Metab. (Current drug metabolism)
[2020, 21(1):53-62]

Cited: 0 times

View full text PDF listing >>



Exploring inflammatory and apoptotic signatures in distinct Crohn's disease phenotypes: Way towards molecular stratification of patients and targeted therapy.

Biljana Stankovic, Sanja Dragasevic, Kristel Klaassen, Nikola Kotur, Sanja Srzentic Drazilov, Branka Zukic, Aleksandra Sokic Milutinovic, Tamara Milovanovic, Snezana Lukic, Dragan Popovic, Sonja Pavlovic, Gordana Nikcevic,

BACKGROUND:Crohn's disease (CD) is chronic inflammatory bowel disease with different phenotypic characteristics influencing disease prognosis and therapeutic strategies. The aim of this pilot study was to analyze selected inflammatory and apoptotic markers in non-inflamed and inflamed samples of ileal mucosa of non-stricturing/non-penetrating (NS/NP) and stricturing (S) CD mucosal phenotypes in ... Read more >>

Pathol. Res. Pract. (Pathology, research and practice)
[2020, 216(6):152945]

Cited: 0 times

View full text PDF listing >>



Metabolic Syndrome in Inflammatory Bowel Disease: Association with Genetic Markers of Obesity and Inflammation.

Sanja Dragasevic, Biljana Stankovic, Nikola Kotur, Aleksandra Sokic-Milutinovic, Tamara Milovanovic, Snezana Lukic, Tomica Milosavljevic, Sanja Srzentic Drazilov, Kristel Klaassen, Sonja Pavlovic, Dragan Popovic,

Background: This study analyzed poorly understood relationship of two overlapping conditions: metabolic syndrome (MeS) and inflammatory bowel disease (IBD), both associated with inflammation in the visceral adipose tissue. Methods: Newly diagnosed 104 IBD patients, of which 50 Crohn's disease (CD) and 54 ulcerative colitis (UC), and 45 non-IBD controls were ... Read more >>

Metab Syndr Relat Disord (Metabolic syndrome and related disorders)
[2020, 18(1):31-38]

Cited: 0 times

View full text PDF listing >>



Influence of variants in folate metabolism genes on 6-mercaptopurine induced toxicity during treatment for childhood acute lymphocytic leukemia.

Goran Milosevic, Nikola Kotur, Jelena Lazic, Nada Krstovski, Biljana Stankovic, Branka Zukic, Dragana Janic, Vladimir Jurisic, Sonja Pavlovic, Lidija Dokmanovic,

PURPOSE:To analyze influence of variants in TYMS, MTHFR, SLC19A1 and DHFR genes on 6-mercaptopurine (MP) induced toxicity during maintenance phase of treatment for childhood acute lymphocytic leukemia (ALL). METHODS:One-hundred twenty-seven children with ALL that received maintenance therapy were involved in this study. All patients were treated according to Berlin-Frankfurt-Muenster (BFM) ... Read more >>

J BUON (Journal of B.U.ON. : official journal of the Balkan Union of Oncology)
[2019, 24(5):2075-2083]

Cited: 0 times

View full text PDF listing >>



Expression Pattern of Long Non-coding RNA Growth Arrest-specific 5 in the Remission Induction Therapy in Childhood Acute Lymphoblastic Leukemia.

Vladimir Gasic, Biljana Stankovic, Branka Zukic, Dragana Janic, Lidija Dokmanovic, Nada Krstovski, Jelena Lazic, Goran Milosevic, Marianna Lucafò, Gabriele Stocco, Giuliana Decorti, Sonja Pavlovic, Nikola Kotur,

Background:Long non-coding RNA growth arrest-specific 5 (GAS5) is deregulated in many cancers because of its role in cell growth arrest and apoptosis. Additionally, GAS5 interacts with glucocorticoid receptor, making it a potential pharmacotranscription marker of glucocorticoid (GC) therapy. In this study, we aimed at analysing GAS5 expression in the remission ... Read more >>

J Med Biochem (Journal of medical biochemistry)
[2019, 38(3):292-298]

Cited: 1 time

View full text PDF listing >>



Pharmacogenomic and Pharmacotranscriptomic Profiling of Childhood Acute Lymphoblastic Leukemia: Paving the Way to Personalized Treatment.

Sonja Pavlovic, Nikola Kotur, Biljana Stankovic, Branka Zukic, Vladimir Gasic, Lidija Dokmanovic,

Personalized medicine is focused on research disciplines which contribute to the individualization of therapy, like pharmacogenomics and pharmacotranscriptomics. Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood. It is one of the pediatric malignancies with the highest cure rate, but still a lethal outcome due to therapy accounts ... Read more >>

Genes (Basel) (Genes)
[2019, 10(3):]

Cited: 0 times

View full text PDF listing >>



How (Ir)rational Is it to Believe in Contradictory Conspiracy Theories?

Petar Lukić, Iris Žeželj, Biljana Stanković,

There is evidence that not only believing in one conspiracy theory (CT) makes a person more probable to believe in others, however unrelated their content is, but that people can even believe in contradictory CTs about a single event. After piloting locally relevant conspiracy theories on a convenient Serbian speaking ... Read more >>

Eur J Psychol (Europe's journal of psychology)
[2019, 15(1):94-107]

Cited: 1 time

View full text PDF listing >>



Pharmacogenomic markers of glucocorticoid response in the initial phase of remission induction therapy in childhood acute lymphoblastic leukemia.

Vladimir Gasic, Branka Zukic, Biljana Stankovic, Dragana Janic, Lidija Dokmanovic, Jelena Lazic, Nada Krstovski, Vita Dolzan, Janez Jazbec, Sonja Pavlovic, Nikola Kotur,

Background Response to glucocorticoid (GC) monotherapy in the initial phase of remission induction treatment in childhood acute lymphoblastic leukemia (ALL) represents important biomarker of prognosis and outcome. We aimed to study variants in several pharmacogenes (NR3C1, GSTs and ABCB1) that could contribute to improvement of GC response through personalization of ... Read more >>

Radiol Oncol (Radiology and oncology)
[2018, 52(3):296-306]

Cited: 1 time

View full text PDF listing >>



Importance of TLR9-IL23-IL17 axis in inflammatory bowel disease development: Gene expression profiling study.

Sanja Dragasevic, Biljana Stankovic, Aleksandra Sokic-Milutinovic, Tomica Milosavljevic, Tamara Milovanovic, Snezana Lukic, Sanja Srzentic Drazilov, Kristel Klaassen, Nikola Kotur, Sonja Pavlovic, Dragan Popovic,

BACKGROUND AND AIMS:Mucosal gene expression have not been fully enlightened in inflammatory bowel disease (IBD). Aim of this study was to define IL23A, IL17A, IL17F and TLR9 expression in different IBD phenotypes. METHODS:Evaluation of mRNA levels was performed in paired non-inflamed and inflamed mucosal biopsies of newly diagnosed 50 Crohn's ... Read more >>

Clin. Immunol. (Clinical immunology (Orlando, Fla.))
[2018, 197:86-95]

Cited: 1 time

View full text PDF listing >>



Variants in TPMT, ITPA, ABCC4 and ABCB1 Genes As Predictors of 6-mercaptopurine Induced Toxicity in Children with Acute Lymphoblastic Leukemia.

Goran Milosevic, Nikola Kotur, Nada Krstovski, Jelena Lazic, Branka Zukic, Biljana Stankovic, Dragana Janic, Theodora Katsila, George P Patrinos, Sonja Pavlovic, Lidija Dokmanovic,

Background:Acute lymphoblastic leukemia is the most common childhood malignancy. Optimal use of anti leukemic drugs has led to less toxicity and adverse reactions, and a higher survival rate. Thiopurine drugs, including 6-mercaptopurine, are mostly used as antileukemic medications in the maintenance phase of treatment for children with acute lymphoblastic leukemia. ... Read more >>

J Med Biochem (Journal of medical biochemistry)
[2018, 37(3):320-327]

Cited: 4 times

View full text PDF listing >>



Pharmacotranscriptomic Biomarkers in Glucocorticoid Treatment of Pediatric Inflammatory Bowel Disease.

Marianna Lucafò, Biljana Stankovic, Nikola Kotur, Alessia Di Silvestre, Stefano Martelossi, Alessandro Ventura, Branka Zukic, Sonja Pavlovic, Giuliana Decorti,

Pharmacotranscriptomics aims to reach more accurate drug dosing based on interindividual transcriptome variations. Here, we provide an overview of RNA biomarkers that could predict the response to glucocorticoids (GCs), considered the standard for treatment of inflammatory bowel diseases (IBD), both in adult and pediatric patients. Although new biological agents are ... Read more >>

Curr. Med. Chem. (Current medicinal chemistry)
[2018, 25(24):2855-2871]

Cited: 4 times

View full text PDF listing >>



Women's Experiences of Childbirth in Serbian Public Healthcare Institutions: a Qualitative Study.

Biljana Stankovic,

The aim of the present study was to explore how women, users of public maternity healthcare services in Serbia, experience birth and what the most problematic relational aspects of institutional context associated with negative or even traumatic aspects of birth experiences are, as described by the women themselves.An exploratory qualitative ... Read more >>

Int J Behav Med (International journal of behavioral medicine)
[2017, 24(6):803-814]

Cited: 1 time

View full text PDF listing >>



Dietary amino acid and vitamin complex protects honey bee from immunosuppression caused by Nosema ceranae.

Uros Glavinic, Biljana Stankovic, Vladimir Draskovic, Jevrosima Stevanovic, Tamas Petrovic, Nada Lakic, Zoran Stanimirovic,

Microsporidium Nosema ceranae is well known for exerting a negative impact on honey bee health, including down-regulation of immunoregulatory genes. Protein nutrition has been proven to have beneficial effects on bee immunity and other aspects of bee health. Bearing this in mind, the aim of our study was to evaluate ... Read more >>

PLoS ONE (PloS one)
[2017, 12(11):e0187726]

Cited: 6 times

View full text PDF listing >>



Genetic and environmental factors significant for the presentation and development of inflammatory bowel disease.

Sanja Dragasevic, Biljana Stankovic, Tomica Milosavljevic, Aleksandra Sokic-Milutinovic, Snezana Lukic, Tamara Alempijevic, Branka Zukic, Nikola Kotur, Gordana Nikcevic, Sonja Pavlovic, Dragan Popovic,

The aim of the study was to evaluate associations between inflammatory bowel disease (IBD) presentation and variants in NOD2, TLR4, TNF-α, IL-6, IL-1β, and IL-RN genes in order to identify possible environmental factors that may affect IBD occurrence, investigate potential predictors for surgical treatment of IBD, and correlate the presence ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2017, 29(8):909-915]

Cited: 1 time

View full text PDF listing >>



Genetic predictors of celiac disease, lactose intolerance, and vitamin D function and presence of peptide morphins in urine of children with neurodevelopmental disorders.

Katarina Bojović, Biljana Stanković, Nikola Kotur, Dijana Krstić-Milošević, Vladimir Gašić, Sonja Pavlović, Branka Zukić, Đurđica Ignjatović,

Gastrointestinal disturbances, nutritional deficiencies, and food intolerances are frequently observed in children with neurodevelopmental disorders (NDD). To reveal possible association of celiac disease risk variants (HLA-DQ), lactose intolerance associated variant (LCT-13910C>T) as well as variant associated with vitamin D function (VDR FokI) with NDD, polymerase chain reaction-based methodology was used. ... Read more >>

Nutr Neurosci (Nutritional neuroscience)
[2019, 22(1):40-50]

Cited: 0 times

View full text PDF listing >>



118.2 The Signature of Trauma in Psychosis: A Preliminary Genetic and Epigenetic Analyses of FK506-Binding Protein 5 Regulation.

Nadja Maric, Marina Mihaljevic, Dusanka Franic, Ivan Soldatovic, Sanja Andric, Iva Lukic, Tijana Mirjanic, Biljana Stankovic, Branka Zukic, Valerija Dobricic, Ivana Novakovic, Sonja Pavlovic, Miroslav Adzic,

Abstract Epigenetic changes of the FKBP5 locus in adults were reported to be allele specific and trauma related in different patient populations. However, DNA methylation status of FKBP5 and its relation to the circulating protein levels are still unknown in schizophrenia spectrum disorders. This pilot study of homogeneous ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2017, 43(Suppl 1):S66-S66]

Cited: 0 times

View full text PDF listing >>



Novel genetic risk variants for pediatric celiac disease.

Angeliki Balasopoulou, Biljana Stanković, Angeliki Panagiotara, Gordana Nikčevic, Brock A Peters, Anne John, Effrosyni Mendrinou, Apostolos Stratopoulos, Aigli Ioanna Legaki, Vasiliki Stathakopoulou, Aristoniki Tsolia, Nikolaos Govaris, Sofia Govari, Zoi Zagoriti, Konstantinos Poulas, Maria Kanariou, Nikki Constantinidou, Maro Krini, Kleopatra Spanou, Nedeljko Radlovic, Bassam R Ali, Joseph Borg, Radoje Drmanac, George Chrousos, Sonja Pavlovic, Eleftheria Roma, Branka Zukic, George P Patrinos, Theodora Katsila,

Celiac disease is a complex chronic immune-mediated disorder of the small intestine. Today, the pathobiology of the disease is unclear, perplexing differential diagnosis, patient stratification, and decision-making in the clinic.Herein, we adopted a next-generation sequencing approach in a celiac disease trio of Greek descent to identify all genomic variants with ... Read more >>

Hum. Genomics (Human genomics)
[2016, 10(1):34]

Cited: 2 times

View full text PDF listing >>



Situated technology in reproductive health care: Do we need a new theory of the subject to promote person-centred care?

Biljana Stankovic,

Going through reproductive experiences (especially pregnancy and childbirth) in contemporary Western societies almost inevitably involves interaction with medical practitioners and various medical technologies in institutional context. This has important consequences for women as embodied subjects. A critical appraisal of these consequences-coming dominantly from feminist scholarship-relied on a problematic theory of ... Read more >>

Nurs Philos (Nursing philosophy : an international journal for healthcare professionals)
[2017, 18(1):]

Cited: 0 times

View full text PDF listing >>



New PAH gene promoter KLF1 and 3'-region C/EBPalpha motifs influence transcription in vitro.

Kristel Klaassen, Biljana Stankovic, Nikola Kotur, Maja Djordjevic, Branka Zukic, Gordana Nikcevic, Milena Ugrin, Vesna Spasovski, Sanja Srzentic, Sonja Pavlovic, Maja Stojiljkovic,

Phenylketonuria (PKU) is a metabolic disease caused by mutations in the phenylalanine hydroxylase (PAH) gene. Although the PAH genotype remains the main determinant of PKU phenotype severity, genotype-phenotype inconsistencies have been reported. In this study, we focused on unanalysed sequences in non-coding PAH gene regions to assess their possible influence ... Read more >>

J. Appl. Genet. (Journal of applied genetics)
[2017, 58(1):79-85]

Cited: 1 time

View full text PDF listing >>



Frequencies of EGFR single nucleotide polymorphisms in non-small cell lung cancer patients and healthy individuals in the Republic of Serbia: a preliminary study.

Jasmina Obradović, Natasa Djordjević, Natasa Tošic, Jasminka Mrdjanović, Biljana Stanković, Jelena Stanić, Bojan Zarić, Branislav Perin, Sonja Pavlović, Vladimir Jurišić,

The purpose of this study was to determine the frequencies of EGFR -216G>T, -191C>A, and 181946C>T in Serbian non-small cell lung cancer (NSCLC) patients, as well as to compare it with healthy individuals, in order to assess their potential importance for lung cancer in Serbia. The study involved 56 NSCLC ... Read more >>

Tumour Biol. (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine)
[2016, 37(8):10479-10486]

Cited: 2 times

View full text PDF listing >>



TPMT gene expression is increased during maintenance therapy in childhood acute lymphoblastic leukemia patients in a TPMT gene promoter variable number of tandem repeat-dependent manner.

Nikola Kotur, Lidija Dokmanovic, Dragana Janic, Biljana Stankovic, Nada Krstovski, Natasa Tosic, Theodora Katsila, George P Patrinos, Branka Zukic, Sonja Pavlovic,

6-mercaptopurine influences in vitro TPMT gene expression in a TPMT promoter variable number of tandem repeats (VNTR)-dependent manner. We studied TPMT expression following 6-mercaptopurine and methotrexate administration in childhood acute lymphoblastic leukemia (ALL) patients and the pharmacogenomic potential of the VNTR architecture.TPMT gene expression was determined in childhood ALL patients ... Read more >>

Pharmacogenomics (Pharmacogenomics)
[2015, 16(15):1701-1712]

Cited: 9 times

View full text PDF listing >>



Variations in inflammatory genes as molecular markers for prediction of inflammatory bowel disease occurrence.

Biljana Stankovic, Sanja Dragasevic, Dragan Popovic, Branka Zukic, Nikola Kotur, Aleksandra Sokic-Milutinovic, Tamara Alempijevic, Snezana Lukic, Tomica Milosavljevic, Gordana Nikcevic, Sonja Pavlovic,

Research on inflammatory bowel disease (IBD) has highlighted genes involved in the regulation of inflammatory responses as contributors to disease pathogenesis. This study aimed to evaluate the associations between IBD and variations in NOD2, TLR4, TNF-α, IL-6, IL-1β and IL-1RN genes, and to use the genetic data obtained in predictive ... Read more >>

J Dig Dis (Journal of digestive diseases)
[2015, 16(12):723-733]

Cited: 4 times

View full text PDF listing >>



Association of gene variants in TLR4 and IL-6 genes with Perthes disease.

Sanja Srzentić, Vesna Spasovski, Dusko Spasovski, Zorica Zivković, Dragana Matanović, Zoran Bascarević, Zorica Terzić Supić, Maja Stojiljković, Teodora Karan-Djurasević, Biljana Stanković, Sonja Pavlović, Gordana Nikcević, Zoran Vukasinović,

Perthes disease is idiopathic avascular osteonecrosis of the hip in children, with unknown etiology. Inflammation is present during development of Perthes disease and it is known that this process influences bone remodeling.Since genetic studies related to inflammation have not been performed in Perthes disease so far, the aim of this ... Read more >>

Srp Arh Celok Lek (Srpski arhiv za celokupno lekarstvo)
[2014, 142(7-8):450-456]

Cited: 8 times

View full text PDF listing >>



Advertisement

Disclaimer
1.0746 s