Full Text Journal Articles by
Author Bennett W Fox

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Toward spatially resolved metabolomics.

Bennett W Fox, Frank C Schroeder,

Nat. Chem. Biol. (Nature chemical biology)
[2020, 16(10):1039-1040]

Cited: 0 times

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Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach.

Jason S Hoki, Henry H Le, Karlie E Mellott, Ying K Zhang, Bennett W Fox, Pedro R Rodrigues, Yan Yu, Maximilian J Helf, Joshua A Baccile, Frank C Schroeder,

Untargeted metabolomics indicates that the number of unidentified small-molecule metabolites may exceed the number of protein-coding genes for many organisms, including humans, by orders of magnitude. Uncovering the underlying metabolic networks is essential for elucidating the physiological and ecological significance of these biogenic small molecules. Here we develop a click-chemistry-based ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2020, :]

Cited: 0 times

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A neurotransmitter produced by gut bacteria modulates host sensory behaviour.

Michael P O'Donnell, Bennett W Fox, Pin-Hao Chao, Frank C Schroeder, Piali Sengupta,

Animals coexist in commensal, pathogenic or mutualistic relationships with complex communities of diverse organisms, including microorganisms1. Some bacteria produce bioactive neurotransmitters that have previously been proposed to modulate nervous system activity and behaviours of their hosts2,3. However, the mechanistic basis of this microbiota-brain signalling and its physiological relevance are largely ... Read more >>

Nature (Nature)
[2020, 583(7816):415-420]

Cited: 0 times

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Neurodegeneration: Problems at the nuclear pore.

Bennett W Fox, Randal S Tibbetts,

Nature (Nature)
[2015, 525(7567):36-37]

Cited: 6 times

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Pheromone sensing regulates Caenorhabditis elegans lifespan and stress resistance via the deacetylase SIR-2.1.

Andreas H Ludewig, Yevgeniy Izrayelit, Donha Park, Rabia U Malik, Anna Zimmermann, Parag Mahanti, Bennett W Fox, Axel Bethke, Frank Doering, Donald L Riddle, Frank C Schroeder,

Lifespan in Caenorhabditis elegans, Drosophila, and mice is regulated by conserved signaling networks, including the insulin/insulin-like growth factor 1 (IGF-1) signaling cascade and pathways depending on sirtuins, a family of NAD(+)-dependent deacetylases. Small molecules such as resveratrol are of great interest because they increase lifespan in many species in a ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2013, 110(14):5522-5527]

Cited: 42 times

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A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans.

Chirag Pungaliya, Jagan Srinivasan, Bennett W Fox, Rabia U Malik, Andreas H Ludewig, Paul W Sternberg, Frank C Schroeder,

Small molecule metabolites play important roles in Caenorhabditis elegans biology, but effective approaches for identifying their chemical structures are lacking. Recent studies revealed that a family of glycosides, the ascarosides, differentially regulate C. elegans development and behavior. Low concentrations of ascarosides attract males and thus appear to be part of ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2009, 106(19):7708-7713]

Cited: 113 times

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