Full Text Journal Articles by
Author Bart N Lambrecht

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Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma.

Hamida Hammad, Bart N Lambrecht,

Nat Immunol (Nature immunology)
[2020, 21(11):1313-1314]

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Clarifying the translational potential of B-I09.

Juan R Del Valle, Brian C Betts, Xue-Zhong Yu, Sophie Janssens, Bart N Lambrecht, M Celeste Simon, Chih-Chi Andrew Hu,

Nat Chem Biol (Nature chemical biology)
[2020, 16(11):1152]

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Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells.

Annemiek Uvyn, Ruben De Coen, Olivier De Wever, Kim Deswarte, Bart N Lambrecht, Bruno G De Geest,

Triggering antibody-mediated innate immune mechanisms to kill cancer cells is an attractive therapeutic avenue. In this context, recruitment of endogenous antibodies to the cancer cell surface could be a viable alternative to the use of monoclonal antibodies. We report on antibody-recruiting polymers containing multiple antibody-binding hapten motifs and cyclooctynes that ... Read more >>

Chem. Commun. (Camb.) (Chemical communications (Cambridge, England))
[2019, 55(73):10952-10955]

Cited: 1 time

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Surgery in Nasal Polyp Patients: Outcome After a Minimum Observation of 10 Years.

Stephan Vlaminck, Frederic Acke, Emmanuel Prokopakis, Kato Speleman, Hideyuki Kawauchi, Jean-Christophe van Cutsem, Peter W Hellings, Mark Jorissen, Sven Seys, Claus Bachert, Thibaut Van Zele, Bart N Lambrecht, Philippe Gevaert,

BACKGROUND:Chronic rhinosinusitis with nasal polyps (CRSwNP) often requires surgery, but recurrence even after surgery is common. Recurrence rates largely vary in literature and asthma seems to be a comorbid factor. OBJECTIVE:In this study, we aim to estimate disease recurrence during a long-term follow-up, together with the investigation of possible predicting ... Read more >>

Am J Rhinol Allergy (American journal of rhinology & allergy)
[2020, :1945892420961964]

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Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene.

Lynn Backers, Bram Parton, Marieke De Bruyne, Simon J Tavernier, Kris Van Den Bogaert, Bart N Lambrecht, Filomeen Haerynck, Kathleen B M Claes,

Pathogenic biallelic variants in the BLM/RECQL3 gene cause a rare autosomal recessive disorder called Bloom syndrome (BS). This syndrome is characterized by severe growth delay, immunodeficiency, dermatological manifestations and a predisposition to a wide variety of cancers, often multiple and very early in life. Literature shows that the main mode ... Read more >>

Clin Genet (Clinical genetics)
[2020, :]

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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

Qian Zhang, Paul Bastard, Zhiyong Liu, Jérémie Le Pen, Marcela Moncada-Velez, Jie Chen, Masato Ogishi, Ira K D Sabli, Stephanie Hodeib, Cecilia Korol, Jérémie Rosain, Kaya Bilguvar, Junqiang Ye, Alexandre Bolze, Benedetta Bigio, Rui Yang, Andrés Augusto Arias, Qinhua Zhou, Yu Zhang, Fanny Onodi, Sarantis Korniotis, Léa Karpf, Quentin Philippot, Marwa Chbihi, Lucie Bonnet-Madin, Karim Dorgham, Nikaïa Smith, William M Schneider, Brandon S Razooky, Hans-Heinrich Hoffmann, Eleftherios Michailidis, Leen Moens, Ji Eun Han, Lazaro Lorenzo, Lucy Bizien, Philip Meade, Anna-Lena Neehus, Aileen Camille Ugurbil, Aurélien Corneau, Gaspard Kerner, Peng Zhang, Franck Rapaport, Yoann Seeleuthner, Jeremy Manry, Cecile Masson, Yohann Schmitt, Agatha Schlüter, Tom Le Voyer, Taushif Khan, Juan Li, Jacques Fellay, Lucie Roussel, Mohammad Shahrooei, Mohammed F Alosaimi, Davood Mansouri, Haya Al-Saud, Fahd Al-Mulla, Feras Almourfi, Saleh Zaid Al-Muhsen, Fahad Alsohime, Saeed Al Turki, Rana Hasanato, Diederik van de Beek, Andrea Biondi, Laura Rachele Bettini, Mariella D'Angio', Paolo Bonfanti, Luisa Imberti, Alessandra Sottini, Simone Paghera, Eugenia Quiros-Roldan, Camillo Rossi, Andrew J Oler, Miranda F Tompkins, Camille Alba, Isabelle Vandernoot, Jean-Christophe Goffard, Guillaume Smits, Isabelle Migeotte, Filomeen Haerynck, Pere Soler-Palacin, Andrea Martin-Nalda, Roger Colobran, Pierre-Emmanuel Morange, Sevgi Keles, Fatma Çölkesen, Tayfun Ozcelik, Kadriye Kart Yasar, Sevtap Senoglu, Şemsi Nur Karabela, Carlos Rodríguez-Gallego, Giuseppe Novelli, Sami Hraiech, Yacine Tandjaoui-Lambiotte, Xavier Duval, Cédric Laouénan, , , , , , , , , Andrew L Snow, Clifton L Dalgard, Joshua D Milner, Donald C Vinh, Trine H Mogensen, Nico Marr, András N Spaan, Bertrand Boisson, Bertrand Boisson, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Anne Puel, Michael J Ciancanelli, Isabelle Meyts, Tom Maniatis, Vassili Soumelis, Ali Amara, Michel Nussenzweig, Adolfo García-Sastre, Florian Krammer, Aurora Pujol, Darragh Duffy, Richard P Lifton, Shen-Ying Zhang, Guy Gorochov, Vivien Béziat, Emmanuelle Jouanguy, Vanessa Sancho-Shimizu, Charles M Rice, Laurent Abel, Luigi D Notarangelo, Aurélie Cobat, Helen C Su, Jean-Laurent Casanova,

Clinical outcome upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from silent infection to lethal coronavirus disease 2019 (COVID-19). We have found an enrichment in rare variants predicted to be loss-of-function (LOF) at the 13 human loci known to govern Toll-like receptor 3 (TLR3)- and interferon regulatory ... Read more >>

Science (Science (New York, N.Y.))
[2020, 370(6515):]

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Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study.

Isabelle Meyts, Giorgia Bucciol, Isabella Quinti, Bénédicte Neven, Alain Fischer, Elena Seoane, Eduardo Lopez-Granados, Carla Gianelli, Angel Robles-Marhuenda, Pierre-Yves Jeandel, Catherine Paillard, Vijay G Sankaran, Yesim Yilmaz Demirdag, Vassilios Lougaris, Alessandro Aiuti, Alessandro Plebani, Cinzia Milito, Virgil Ash Dalm, Kissy Guevara-Hoyer, Silvia Sánchez-Ramón, Liliana Bezrodnik, Federica Barzaghi, Luis Ignacio Gonzalez-Granado, Grant R Hayman, Gulbu Uzel, Leonardo Oliveira Mendonça, Carlo Agostini, Giuseppe Spadaro, Raffaele Badolato, Annarosa Soresina, François Vermeulen, Cedric Bosteels, Bart N Lambrecht, Michael Keller, Peter J Mustillo, Roshini S Abraham, Sudhir Gupta, Ahmet Ozen, Elif Karakoc-Aydiner, Safa Baris, Alexandra Freeman, Marco Yamazaki-Nakashimada, Selma Scheffler-Mendoza, Sara Espinosa-Padilla, Andrew R Gennery, Stephen Jolles, Yasmin Espinoza, M Cecilia Poli, Claire Fieschi, Fabian Hauck, Charlotte Cunningham-Rundles, Nizar Mahlaoui, , Klaus Warnatz, Kathleen E Sullivan, Stuart G Tangye,

BACKGROUND:There is uncertainty about the impact of SARS-CoV-2 infection in individuals with rare inborn errors of immunity (IEI), a population at risk of developing severe COVID-19. This is relevant not only for these patients but also the general population, as studies of IEIs can unveil key requirements for host defense. ... Read more >>

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2020, :]

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The global response to the COVID-19 pandemic: how have immunology societies contributed?

Faith Osier, Jenny P Y Ting, John Fraser, Bart N Lambrecht, Marta Romano, Ricardo T Gazzinelli, Karina R Bortoluci, Dario S Zamboni, Arne N Akbar, Jennie Evans, Doug E Brown, Kamala D Patel, Yuzhang Wu, Ana B Perez, Oliver Pérez, Thomas Kamradt, Christine Falk, Mira Barda-Saad, Amiram Ariel, Angela Santoni, Francesco Annunziato, Marco A Cassatella, Hiroshi Kiyono, Valeriy Chereshnev, Alioune Dieye, Moustapha Mbow, Babacar Mbengue, Maguette D S Niang, Melinda Suchard,

The COVID-19 pandemic is shining a spotlight on the field of immunology like never before. To appreciate the diverse ways in which immunologists have contributed, Nature Reviews Immunology invited the president of the International Union of Immunological Societies and the presidents of 15 other national immunology societies to discuss how ... Read more >>

Nat Rev Immunol (Nature reviews. Immunology)
[2020, 20(10):594-602]

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TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.

Zan Li, Hwanhee Oh, Michelle Cung, Sofia Jenia Marquez, Jun Sun, Hamida Hammad, Sophie Janssens, Philippe Pouliot, Bart N Lambrecht, Yeon-Suk Yang, Jae-Hyuck Shim, Matthew B Greenblatt,

Current anabolic drugs to treat osteoporosis and other disorders of low bone mass all have important limitations in terms of toxicity, contraindications, or poor efficacy in certain contexts. Addressing these limitations will require a better understanding of the molecular pathways, such as the mitogen activated protein kinase (MAPK) pathways, that ... Read more >>

Biochem Biophys Res Commun (Biochemical and biophysical research communications)
[2020, 531(4):497-502]

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Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease.

Thomas Naessens, Yannick Morias, Eva Hamrud, Ulf Gehrmann, Ramachandramouli Budida, Johan Mattsson, Tina Baker, Gabriel Skogberg, Elisabeth Israelsson, Kristofer Thörn, Martijn J Schuijs, Bastian Angermann, Faye Melville, Karl J Staples, Danen M Cunoosamy, Bart N Lambrecht,

Rationale: Emerging evidence supports a crucial role for tertiary lymphoid organs (TLOs) in chronic obstructive pulmonary disease (COPD) progression. However, mechanisms of immune cell activation leading to TLOs in COPD remain to be defined.Objectives: To examine the role of lung dendritic cells (DCs) in T follicular helper (Tfh)-cell induction, a ... Read more >>

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 202(4):535-548]

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Correction to: Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial.

Cedric Bosteels, Bastiaan Maes, Karel Van Damme, Elisabeth De Leeuw, Jozefien Declercq, Anja Delporte, Bénédicte Demeyere, Stéfanie Vermeersch, Marnik Vuylsteke, Joren Willaert, Laura Bollé, Yuri Vanbiervliet, Jana Decuypere, Frederick Libeer, Stefaan Vandecasteele, Isabelle Peene, Bart N Lambrecht,

An amendment to this paper has been published and can be accessed via the original article. ... Read more >>

Trials (Trials)
[2020, 21(1):554]

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Correction to: Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial.

Bastiaan Maes, Cedric Bosteels, Elisabeth De Leeuw, Jozefien Declercq, Karel Van Damme, Anja Delporte, Bénédicte Demeyere, Stéfanie Vermeersch, Marnik Vuylsteke, Joren Willaert, Laura Bollé, Yuri Vanbiervliet, Jana Decuypere, Frederick Libeer, Stefaan Vandecasteele, Isabelle Peene, Bart N Lambrecht,

An amendment to this paper has been published and can be accessed via the original article. ... Read more >>

Trials (Trials)
[2020, 21(1):556]

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An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells.

Sheena C Kerr, Jeanmarie R Gonzalez, Julia Schanin, Michael C Peters, Bart N Lambrecht, Emily C Brock, Annabelle Charbit, K Mark Ansel, Bradford A Youngblood, John V Fahy,

BACKGROUND:Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is expressed on mast cells and eosinophils, but information about Siglec-8 expression and function in the lung is limited. A humanized antibody, AK002, targeting Siglec-8 is undergoing development for treatment of diseases associated with mast cell and eosinophil-driven inflammation. OBJECTIVE:To characterize Siglec-8 expression in the ... Read more >>

Clin Exp Allergy (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology)
[2020, :]

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Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.

Vivien Béziat, Simon J Tavernier, Yin-Huai Chen, Cindy S Ma, Marie Materna, Arian Laurence, Jens Staal, Dominik Aschenbrenner, Lisa Roels, Lisa Worley, Kathleen Claes, Lisa Gartner, Lisa A Kohn, Marieke De Bruyne, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Sevgi Keles, Justine Nammour, Natasha Vladikine, Majistor Raj Luxman Maglorius Renkilaraj, Yoann Seeleuthner, Mélanie Migaud, Jérémie Rosain, Mohamed Jeljeli, Bertrand Boisson, Eva Van Braeckel, Jill A Rosenfeld, Hongzheng Dai, Lindsay C Burrage, David R Murdock, Bart N Lambrecht, Véronique Avettand-Fenoel, Tiphanie P Vogel, , Charles R Esther, Sule Haskologlu, Figen Dogu, Peter Ciznar, David Boutboul, Marie Ouachée-Chardin, Jean Amourette, Marie-Noëlle Lebras, Clément Gauvain, Colas Tcherakian, Aydan Ikinciogullari, Rudi Beyaert, Laurent Abel, Joshua D Milner, Bodo Grimbacher, Louis-Jean Couderc, Manish J Butte, Alexandra F Freeman, Émilie Catherinot, Claire Fieschi, Talal A Chatila, Stuart G Tangye, Holm H Uhlig, Filomeen Haerynck, Jean-Laurent Casanova, Anne Puel,

Autosomal dominant hyper-IgE syndrome (AD-HIES) is typically caused by dominant-negative (DN) STAT3 mutations. Patients suffer from cold staphylococcal lesions and mucocutaneous candidiasis, severe allergy, and skeletal abnormalities. We report 12 patients from 8 unrelated kindreds with AD-HIES due to DN IL6ST mutations. We identified seven different truncating mutations, one of ... Read more >>

J. Exp. Med. (The Journal of experimental medicine)
[2020, 217(6):]

Cited: 1 time

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Tnfaip3 expression in pulmonary conventional type 1 Langerin-expressing dendritic cells regulates T helper 2-mediated airway inflammation in mice.

Heleen Vroman, Denise van Uden, Ingrid M Bergen, Jennifer A C van Hulst, Melanie Lukkes, Geert van Loo, Björn E Clausen, Louis Boon, Bart N Lambrecht, Hamida Hammad, Rudi W Hendriks, Mirjam Kool,

BACKGROUND:Conventional type 1 dendritic cells (cDC1s) control anti-viral and anti-tumor immunity by inducing antigen-specific cytotoxic CD8+ T-cell responses. Controversy exists whether cDC1s also control CD4+ T helper 2 (Th2) cell responses, since suppressive and activating roles have been reported. DC activation status, controlled by the transcription factor NF-κB, might determine ... Read more >>

Allergy (Allergy)
[2020, 75(10):2587-2598]

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Correction: Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.

Vivien Béziat, Simon J Tavernier, Yin-Huai Chen, Cindy S Ma, Marie Materna, Arian Laurence, Jens Staal, Dominik Aschenbrenner, Lisa Roels, Lisa Worley, Kathleen Claes, Lisa Gartner, Lisa A Kohn, Marieke De Bruyne, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Sevgi Keles, Justine Nammour, Natasha Vladikine, Majistor Raj Luxman Maglorius Renkilaraj, Yoann Seeleuthner, Mélanie Migaud, Jérémie Rosain, Mohamed Jeljeli, Bertrand Boisson, Eva Van Braeckel, Jill A Rosenfeld, Hongzheng Dai, Lindsay C Burrage, David R Murdock, Bart N Lambrecht, Véronique Avettand-Fenoel, Tiphanie P Vogel, Undiagnosed Diseases Network, Charles R Esther, Sule Haskologlu, Figen Dogu, Peter Ciznar, David Boutboul, Marie Ouachée-Chardin, Jean Amourette, Marie-Noëlle Lebras, Clément Gauvain, Colas Tcherakian, Aydan Ikinciogullari, Rudi Beyaert, Laurent Abel, Joshua D Milner, Bodo Grimbacher, Louis-Jean Couderc, Manish J Butte, Alexandra F Freeman, Émilie Catherinot, Claire Fieschi, Talal A Chatila, Stuart G Tangye, Holm H Uhlig, Filomeen Haerynck, Jean-Laurent Casanova, Anne Puel,

J. Exp. Med. (The Journal of experimental medicine)
[2020, 217(7):]

Cited: 0 times

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Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.

Cedric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary J van Helden, Dorine Sichien, Nincy Debeuf, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens, Yvan Saeys, Els Louagie, Manon Lesage, David L Williams, Shiau-Choot Tang, Johannes U Mayer, Franca Ronchese, Charlotte L Scott, Hamida Hammad, Martin Guilliams, Bart N Lambrecht,

The phenotypic and functional dichotomy between IRF8+ type 1 and IRF4+ type 2 conventional dendritic cells (cDC1s and cDC2s, respectively) is well accepted; it is unknown how robust this dichotomy is under inflammatory conditions, when additionally monocyte-derived cells (MCs) become competent antigen-presenting cells (APCs). Using single-cell technologies in models of ... Read more >>

Immunity (Immunity)
[2020, 52(6):1039-1056.e9]

Cited: 0 times

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Rbm7 in Structural Cells: A NEAT Way to Control Fibrosis.

Hamida Hammad, Bart N Lambrecht,

The initial molecular events and the cell type(s) responsible for the development of fibrosis are unclear. Fukushima, Satoh, et al. find that increased expression of the nuclear exosome targeting complex component Rbm7 in lung epithelial cells promotes the degradation of the long non-coding RNA NEAT1, impairs DNA repair, and triggers apoptosis. ... Read more >>

Immunity (Immunity)
[2020, 52(3):429-431]

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Short-term preoperative protein restriction attenuates vein graft disease via induction of cystathionine γ-lyase.

Kaspar M Trocha, Peter Kip, Ming Tao, Michael R MacArthur, J Humberto Treviño-Villarreal, Alban Longchamp, Wendy Toussaint, Bart N Lambrecht, Margreet R de Vries, Paul H A Quax, James R Mitchell, C Keith Ozaki,

AIMS:Therapies to prevent vein graft disease, a major problem in cardiovascular and lower extremity bypass surgeries, are currently lacking. Short-term preoperative protein restriction holds promise as an effective preconditioning method against surgical stress in rodent models, but whether it can improve vein graft patency after bypass surgery is undetermined. Here, ... Read more >>

Cardiovasc. Res. (Cardiovascular research)
[2020, 116(2):416-428]

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GATA2 deficiency and haematopoietic stem cell transplantation: challenges for the clinical practitioner.

Delfien J Bogaert, Genevieve Laureys, Leslie Naesens, Dominiek Mazure, Marieke De Bruyne, Amy P Hsu, Victoria Bordon, Erik Wouters, Simon J Tavernier, Bart N Lambrecht, Elfride De Baere, Filomeen Haerynck, Tessa Kerre,

GATA2 deficiency, first described in 2011, is a bone marrow failure disorder resulting in a complex haematological and immunodeficiency syndrome characterised by cytopenias, severe infections, myelodysplasia and leukaemia. The only curative treatment is allogeneic haematopoietic stem cell transplantation (HSCT). Although knowledge on this syndrome has greatly expanded, in clinical practice ... Read more >>

Br J Haematol (British journal of haematology)
[2020, 188(5):768-773]

Cited: 0 times

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Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy.

Cristina Gil-Cruz, Christian Perez-Shibayama, Angelina De Martin, Francesca Ronchi, Katrien van der Borght, Rebekka Niederer, Lucas Onder, Mechthild Lütge, Mario Novkovic, Veronika Nindl, Gustavo Ramos, Markus Arnoldini, Emma M C Slack, Valérie Boivin-Jahns, Roland Jahns, Madeleine Wyss, Catherine Mooser, Bart N Lambrecht, Micha T Maeder, Hans Rickli, Lukas Flatz, Urs Eriksson, Markus B Geuking, Kathy D McCoy, Burkhard Ludewig,

Myocarditis can develop into inflammatory cardiomyopathy through chronic stimulation of myosin heavy chain 6-specific T helper (TH)1 and TH17 cells. However, mechanisms governing the cardiotoxicity programming of heart-specific T cells have remained elusive. Using a mouse model of spontaneous autoimmune myocarditis, we show that progression of myocarditis to lethal heart ... Read more >>

Science (Science (New York, N.Y.))
[2019, 366(6467):881-886]

Cited: 3 times

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Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists.

Jana De Vrieze, Benoit Louage, Kim Deswarte, Zifu Zhong, Ruben De Coen, Simon Van Herck, Lutz Nuhn, Camilla Kaas Frich, Alexander N Zelikin, Stefan Lienenklaus, Niek N Sanders, Bart N Lambrecht, Sunil A David, Bruno G De Geest,

Uncontrolled systemic inflammatory immune triggering has hampered the clinical translation of several classes of small-molecule immunomodulators, such as imidazoquinoline TLR7/8 agonists for vaccine design and cancer immunotherapy. By taking advantage of the inherent serum-protein-binding property of lipid motifs and their tendency to accumulate in lymphoid tissue, we designed amphiphilic lipid-polymer ... Read more >>

Angew Chem Int Ed Engl (Angewandte Chemie (International ed. in English))
[2019, 58(43):15390-15395]

Cited: 1 time

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Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.

Johnny Bonnardel, Wouter T'Jonck, Djoere Gaublomme, Robin Browaeys, Charlotte L Scott, Liesbet Martens, Bavo Vanneste, Sofie De Prijck, Sergei A Nedospasov, Anna Kremer, Evelien Van Hamme, Peter Borghgraef, Wendy Toussaint, Pieter De Bleser, Inge Mannaerts, Alain Beschin, Leo A van Grunsven, Bart N Lambrecht, Tom Taghon, Saskia Lippens, Dirk Elewaut, Yvan Saeys, Martin Guilliams,

Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific identities of macrophages in their respective niches. Using conditional depletion of liver Kupffer cells, we traced the developmental stages of monocytes differentiating into Kupffer cells and mapped the cellular ... Read more >>

Immunity (Immunity)
[2019, 51(4):638-654.e9]

Cited: 12 times

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How a farming environment protects from atopy.

Julie Deckers, Bart N Lambrecht, Hamida Hammad,

It is now well established that the exposure to certain environments such as farms has the potential to protect from the development of allergies later in life. This protection is achieved when repeated exposure to the farming environment occurs early in life, but persists when children spend sufficient amount of ... Read more >>

Curr. Opin. Immunol. (Current opinion in immunology)
[2019, 60:163-169]

Cited: 2 times

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Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis.

Elien Gevaert, Tim Delemarre, Joyceline De Volder, Nan Zhang, Gabriele Holtappels, Natalie De Ruyck, Emma Persson, Ines Heyndrickx, Kenneth Verstraete, Helena Aegerter, Hans Nauwynck, Savvas N Savvides, Bart N Lambrecht, Claus Bachert,

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2020, 145(1):427-430.e4]

Cited: 1 time

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